BDBM50024594 (R)-1-Ammonium-3-methyl-butane-1-phosphonic acid anion::CHEMBL40422::LEUCINE PHOSPHONIC ACID

SMILES: CC(C)C[C@H]([NH3+])P(O)([O-])=O

InChI Key: InChIKey=HGCAUCAWEADMPM-RXMQYKEDSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50024594   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine aminopeptidase (LAP) (Sus scrofa (Pig))	BDBM50024594 ((R)-1-Ammonium-3-methyl-butane-1-phosphonic acid a...) Show SMILES CC(C)C[C@H]([NH3+])P(O)([O-])=O Show InChI InChI=1S/C5H14NO3P/c1-4(2)3-5(6)10(7,8)9/h4-5H,3,6H2,1-2H3,(H2,7,8,9)/t5-/m1/s1	GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens Curated by ChEMBL					Assay Description Inhibition of pig recombinant leucine aminopeptidase after 30 to 60 mins by morrison's equation				J Med Chem 57: 8140-51 (2014) Article DOI: 10.1021/jm501071f BindingDB Entry DOI: 10.7270/Q2CF9RQF
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50024594 ((R)-1-Ammonium-3-methyl-butane-1-phosphonic acid a...) Show SMILES CC(C)C[C@H]([NH3+])P(O)([O-])=O Show InChI InChI=1S/C5H14NO3P/c1-4(2)3-5(6)10(7,8)9/h4-5H,3,6H2,1-2H3,(H2,7,8,9)/t5-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens Curated by ChEMBL					Assay Description Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equation				J Med Chem 57: 8140-51 (2014) Article DOI: 10.1021/jm501071f BindingDB Entry DOI: 10.7270/Q2CF9RQF
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50024594 ((R)-1-Ammonium-3-methyl-butane-1-phosphonic acid a...) Show SMILES CC(C)C[C@H]([NH3+])P(O)([O-])=O Show InChI InChI=1S/C5H14NO3P/c1-4(2)3-5(6)10(7,8)9/h4-5H,3,6H2,1-2H3,(H2,7,8,9)/t5-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens Curated by ChEMBL					Assay Description Inhibition of pig recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equation				J Med Chem 57: 8140-51 (2014) Article DOI: 10.1021/jm501071f BindingDB Entry DOI: 10.7270/Q2CF9RQF
					More data for this Ligand-Target Pair
Leucine aminopeptidase (Homo sapiens (Human))	BDBM50024594 ((R)-1-Ammonium-3-methyl-butane-1-phosphonic acid a...) Show SMILES CC(C)C[C@H]([NH3+])P(O)([O-])=O Show InChI InChI=1S/C5H14NO3P/c1-4(2)3-5(6)10(7,8)9/h4-5H,3,6H2,1-2H3,(H2,7,8,9)/t5-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Leucine aminopeptidase isolated from porcine kidney.				J Med Chem 30: 1603-9 (1987) BindingDB Entry DOI: 10.7270/Q2W66MCD
					More data for this Ligand-Target Pair