Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Synaptic vesicular amine transporter (Rattus norvegicus (Rat)) | BDBM50433783 (CHEMBL2381721) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arkansas for Medical Sciences Curated by ChEMBL | Assay Description Inhibition of VMAT2 in rat striatal synaptic vesicle assessed as reduction of [3H]dopamine uptake after 8 mins by liquid scintillation spectrometric ... | Bioorg Med Chem Lett 26: 2422-7 (2016) Article DOI: 10.1016/j.bmcl.2016.03.119 BindingDB Entry DOI: 10.7270/Q2BC41DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Synaptic vesicular amine transporter (Rattus norvegicus (Rat)) | BDBM50157190 (CHEMBL3793321) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arkansas for Medical Sciences Curated by ChEMBL | Assay Description Inhibition of VMAT2 in rat striatal synaptic vesicle assessed as reduction of [3H]dopamine uptake after 8 mins by liquid scintillation spectrometric ... | Bioorg Med Chem Lett 26: 2422-7 (2016) Article DOI: 10.1016/j.bmcl.2016.03.119 BindingDB Entry DOI: 10.7270/Q2BC41DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Synaptic vesicular amine transporter (Rattus norvegicus (Rat)) | BDBM50157301 (CHEMBL3792786) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arkansas for Medical Sciences Curated by ChEMBL | Assay Description Inhibition of VMAT2 in rat striatal synaptic vesicle assessed as reduction of [3H]dopamine uptake after 8 mins by liquid scintillation spectrometric ... | Bioorg Med Chem Lett 26: 2422-7 (2016) Article DOI: 10.1016/j.bmcl.2016.03.119 BindingDB Entry DOI: 10.7270/Q2BC41DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Synaptic vesicular amine transporter (Rattus norvegicus (Rat)) | BDBM50157199 (CHEMBL3793860) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arkansas for Medical Sciences Curated by ChEMBL | Assay Description Inhibition of VMAT2 in rat striatal synaptic vesicle assessed as reduction of [3H]dopamine uptake after 8 mins by liquid scintillation spectrometric ... | Bioorg Med Chem Lett 26: 2422-7 (2016) Article DOI: 10.1016/j.bmcl.2016.03.119 BindingDB Entry DOI: 10.7270/Q2BC41DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Synaptic vesicular amine transporter (Rattus norvegicus (Rat)) | BDBM50157191 (CHEMBL3793365) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 39 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arkansas for Medical Sciences Curated by ChEMBL | Assay Description Inhibition of VMAT2 in rat striatal synaptic vesicle assessed as reduction of [3H]dopamine uptake after 8 mins by liquid scintillation spectrometric ... | Bioorg Med Chem Lett 26: 2422-7 (2016) Article DOI: 10.1016/j.bmcl.2016.03.119 BindingDB Entry DOI: 10.7270/Q2BC41DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Synaptic vesicular amine transporter (Rattus norvegicus (Rat)) | BDBM50157214 (CHEMBL3793720) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arkansas for Medical Sciences Curated by ChEMBL | Assay Description Inhibition of VMAT2 in rat striatal synaptic vesicle assessed as reduction of [3H]dopamine uptake after 8 mins by liquid scintillation spectrometric ... | Bioorg Med Chem Lett 26: 2422-7 (2016) Article DOI: 10.1016/j.bmcl.2016.03.119 BindingDB Entry DOI: 10.7270/Q2BC41DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Synaptic vesicular amine transporter (Rattus norvegicus (Rat)) | BDBM50157154 (CHEMBL3793401) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 46 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arkansas for Medical Sciences Curated by ChEMBL | Assay Description Inhibition of VMAT2 in rat striatal synaptic vesicle assessed as reduction of [3H]dopamine uptake after 8 mins by liquid scintillation spectrometric ... | Bioorg Med Chem Lett 26: 2422-7 (2016) Article DOI: 10.1016/j.bmcl.2016.03.119 BindingDB Entry DOI: 10.7270/Q2BC41DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Synaptic vesicular amine transporter (Rattus norvegicus (Rat)) | BDBM50080827 ((2R,6S)-1-Methyl-2,6-diphenethyl-piperidine | (2S,...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 67 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arkansas for Medical Sciences Curated by ChEMBL | Assay Description Inhibition of VMAT2 in rat striatal synaptic vesicle assessed as reduction of [3H]dopamine uptake after 8 mins by liquid scintillation spectrometric ... | Bioorg Med Chem Lett 26: 2422-7 (2016) Article DOI: 10.1016/j.bmcl.2016.03.119 BindingDB Entry DOI: 10.7270/Q2BC41DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Synaptic vesicular amine transporter (Rattus norvegicus (Rat)) | BDBM50157153 (CHEMBL3793722) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 71 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arkansas for Medical Sciences Curated by ChEMBL | Assay Description Inhibition of VMAT2 in rat striatal synaptic vesicle assessed as reduction of [3H]dopamine uptake after 8 mins by liquid scintillation spectrometric ... | Bioorg Med Chem Lett 26: 2422-7 (2016) Article DOI: 10.1016/j.bmcl.2016.03.119 BindingDB Entry DOI: 10.7270/Q2BC41DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Synaptic vesicular amine transporter (Rattus norvegicus (Rat)) | BDBM50157302 (CHEMBL3792927) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arkansas for Medical Sciences Curated by ChEMBL | Assay Description Inhibition of VMAT2 in rat striatal synaptic vesicle assessed as reduction of [3H]dopamine uptake after 8 mins by liquid scintillation spectrometric ... | Bioorg Med Chem Lett 26: 2422-7 (2016) Article DOI: 10.1016/j.bmcl.2016.03.119 BindingDB Entry DOI: 10.7270/Q2BC41DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Synaptic vesicular amine transporter (Rattus norvegicus (Rat)) | BDBM50157071 (CHEMBL3793895) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arkansas for Medical Sciences Curated by ChEMBL | Assay Description Inhibition of VMAT2 in rat striatal synaptic vesicle assessed as reduction of [3H]dopamine uptake after 8 mins by liquid scintillation spectrometric ... | Bioorg Med Chem Lett 26: 2422-7 (2016) Article DOI: 10.1016/j.bmcl.2016.03.119 BindingDB Entry DOI: 10.7270/Q2BC41DT | |||||||||||
More data for this Ligand-Target Pair |