Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Coagulation factor X (Homo sapiens (Human)) | BDBM19023 (1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-y...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank MMDB PDB Article PubMed | 0.410 | -53.6 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bristol-Myers Squibb Company | Assay Description For comparison with the prothrombinase reaction the assays were also conducted with S2765 at 25 and 37°C in a similar buffer: 20 mM HEPES, pH 7.5 con... | J Enzyme Inhib Med Chem 26: 514-26 (2011) Article DOI: 10.3109/14756366.2010.535793 BindingDB Entry DOI: 10.7270/Q2VX0FDF | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM19023 (1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-y...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank MMDB PDB Article PubMed | 0.720 | -54.3 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
Bristol-Myers Squibb Company | Assay Description For comparison with the prothrombinase reaction the assays were also conducted with S2765 at 25 and 37°C in a similar buffer: 20 mM HEPES, pH 7.5 con... | J Enzyme Inhib Med Chem 26: 514-26 (2011) Article DOI: 10.3109/14756366.2010.535793 BindingDB Entry DOI: 10.7270/Q2VX0FDF | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |