Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Thioredoxin reductase (Plasmodium falciparum (isolate 3D7)) | BDBM50182122 (CHEMBL204688 | bis(2,4-dinitrophenyl)sulfane) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan Curated by ChEMBL | Assay Description Inhibition of Plasmodium falciparum TrxR | Bioorg Med Chem Lett 16: 2283-92 (2006) Article DOI: 10.1016/j.bmcl.2006.01.027 BindingDB Entry DOI: 10.7270/Q2FB52HJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thioredoxin reductase (Plasmodium falciparum (isolate 3D7)) | BDBM50182128 (4-nitrobenzo[c][1,2,5]thiadiazole | CHEMBL383084) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan Curated by ChEMBL | Assay Description Inhibition of Plasmodium falciparum TrxR | Bioorg Med Chem Lett 16: 2283-92 (2006) Article DOI: 10.1016/j.bmcl.2006.01.027 BindingDB Entry DOI: 10.7270/Q2FB52HJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thioredoxin reductase (Plasmodium falciparum (isolate 3D7)) | BDBM50182124 (6,7-dinitroquinoxaline | CHEMBL380953) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan Curated by ChEMBL | Assay Description Inhibition of Plasmodium falciparum TrxR | Bioorg Med Chem Lett 16: 2283-92 (2006) Article DOI: 10.1016/j.bmcl.2006.01.027 BindingDB Entry DOI: 10.7270/Q2FB52HJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thioredoxin reductase (Plasmodium falciparum (isolate 3D7)) | BDBM50068343 (2-Chloro-1,3-dinitro-5-trifluoromethyl-benzene | 2...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan Curated by ChEMBL | Assay Description Inhibition of Plasmodium falciparum TrxR | Bioorg Med Chem Lett 16: 2283-92 (2006) Article DOI: 10.1016/j.bmcl.2006.01.027 BindingDB Entry DOI: 10.7270/Q2FB52HJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thioredoxin reductase (Plasmodium falciparum (isolate 3D7)) | BDBM50182129 (5-nitrobenzo[c][1,2,5]thiadiazole | CHEMBL206713) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan Curated by ChEMBL | Assay Description Inhibition of Plasmodium falciparum TrxR | Bioorg Med Chem Lett 16: 2283-92 (2006) Article DOI: 10.1016/j.bmcl.2006.01.027 BindingDB Entry DOI: 10.7270/Q2FB52HJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thioredoxin reductase (Plasmodium falciparum (isolate 3D7)) | BDBM50182121 (4,5-dinitrobenzo[d][1,3]dioxole | CHEMBL206829) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan Curated by ChEMBL | Assay Description Inhibition of Plasmodium falciparum TrxR | Bioorg Med Chem Lett 16: 2283-92 (2006) Article DOI: 10.1016/j.bmcl.2006.01.027 BindingDB Entry DOI: 10.7270/Q2FB52HJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thioredoxin reductase (Plasmodium falciparum (isolate 3D7)) | BDBM50182130 (4,6-dinitrobenzo[c][1,2,5]thiadiazole | CHEMBL2061...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan Curated by ChEMBL | Assay Description Inhibition of Plasmodium falciparum TrxR | Bioorg Med Chem Lett 16: 2283-92 (2006) Article DOI: 10.1016/j.bmcl.2006.01.027 BindingDB Entry DOI: 10.7270/Q2FB52HJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thioredoxin reductase (Plasmodium falciparum (isolate 3D7)) | BDBM50182125 (CHEMBL204687 | bis(2-nitro-4-(trifluoromethyl)phen...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan Curated by ChEMBL | Assay Description Inhibition of Plasmodium falciparum TrxR | Bioorg Med Chem Lett 16: 2283-92 (2006) Article DOI: 10.1016/j.bmcl.2006.01.027 BindingDB Entry DOI: 10.7270/Q2FB52HJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thioredoxin reductase (Plasmodium falciparum (isolate 3D7)) | BDBM50182126 (1,3-dinitro-5-(trifluoromethyl)benzene | CHEMBL380...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan Curated by ChEMBL | Assay Description Inhibition of Plasmodium falciparum TrxR | Bioorg Med Chem Lett 16: 2283-92 (2006) Article DOI: 10.1016/j.bmcl.2006.01.027 BindingDB Entry DOI: 10.7270/Q2FB52HJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thioredoxin reductase (Plasmodium falciparum (isolate 3D7)) | BDBM50182127 (6-nitroquinoxaline | CHEMBL380630 | TCMDC-123943) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan Curated by ChEMBL | Assay Description Inhibition of Plasmodium falciparum TrxR | Bioorg Med Chem Lett 16: 2283-92 (2006) Article DOI: 10.1016/j.bmcl.2006.01.027 BindingDB Entry DOI: 10.7270/Q2FB52HJ | |||||||||||
More data for this Ligand-Target Pair |