Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM50403738 (CHEMBL351483) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.955 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research Foundation Curated by ChEMBL | Assay Description Binding affinity at human Alpha-2B adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement. | Bioorg Med Chem Lett 10: 71-4 (2000) BindingDB Entry DOI: 10.7270/Q2T72JMX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM50403740 (CHEMBL165350) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research Foundation Curated by ChEMBL | Assay Description Binding affinity at human Alpha-2B adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement. | Bioorg Med Chem Lett 10: 71-4 (2000) BindingDB Entry DOI: 10.7270/Q2T72JMX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM50403739 (CHEMBL163247) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research Foundation Curated by ChEMBL | Assay Description Binding affinity at human Alpha-2B adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement. | Bioorg Med Chem Lett 10: 71-4 (2000) BindingDB Entry DOI: 10.7270/Q2T72JMX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM50403755 (CHEMBL163190) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research Foundation Curated by ChEMBL | Assay Description Binding affinity at human Alpha-2B adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement. | Bioorg Med Chem Lett 10: 71-4 (2000) BindingDB Entry DOI: 10.7270/Q2T72JMX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM50403752 (CHEMBL162370) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research Foundation Curated by ChEMBL | Assay Description Binding affinity at human Alpha-2B adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement. | Bioorg Med Chem Lett 10: 71-4 (2000) BindingDB Entry DOI: 10.7270/Q2T72JMX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM50403747 (CHEMBL162826) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research Foundation Curated by ChEMBL | Assay Description Binding affinity at human Alpha-2B adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement. | Bioorg Med Chem Lett 10: 71-4 (2000) BindingDB Entry DOI: 10.7270/Q2T72JMX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM50403746 (CHEMBL162147) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research Foundation Curated by ChEMBL | Assay Description Binding affinity at human Alpha-2B adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement. | Bioorg Med Chem Lett 10: 71-4 (2000) BindingDB Entry DOI: 10.7270/Q2T72JMX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM50403745 (CHEMBL162490) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research Foundation Curated by ChEMBL | Assay Description Binding affinity at human Alpha-2B adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement. | Bioorg Med Chem Lett 10: 71-4 (2000) BindingDB Entry DOI: 10.7270/Q2T72JMX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM50403753 (CHEMBL162682) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research Foundation Curated by ChEMBL | Assay Description Binding affinity at human Alpha-2B adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement. | Bioorg Med Chem Lett 10: 71-4 (2000) BindingDB Entry DOI: 10.7270/Q2T72JMX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM50403750 (CHEMBL351200) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research Foundation Curated by ChEMBL | Assay Description Binding affinity at human Alpha-2B adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement. | Bioorg Med Chem Lett 10: 71-4 (2000) BindingDB Entry DOI: 10.7270/Q2T72JMX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM50403744 (LUSAPERIDONE) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research Foundation Curated by ChEMBL | Assay Description Binding affinity at human Alpha-2B adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement. | Bioorg Med Chem Lett 10: 71-4 (2000) BindingDB Entry DOI: 10.7270/Q2T72JMX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM50403748 (CHEMBL162232) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research Foundation Curated by ChEMBL | Assay Description Binding affinity at human Alpha-2B adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement. | Bioorg Med Chem Lett 10: 71-4 (2000) BindingDB Entry DOI: 10.7270/Q2T72JMX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM50403742 (CHEMBL165796) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research Foundation Curated by ChEMBL | Assay Description Binding affinity at human Alpha-2B adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement. | Bioorg Med Chem Lett 10: 71-4 (2000) BindingDB Entry DOI: 10.7270/Q2T72JMX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM50403751 (CHEMBL162436) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research Foundation Curated by ChEMBL | Assay Description Binding affinity at human Alpha-2B adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement. | Bioorg Med Chem Lett 10: 71-4 (2000) BindingDB Entry DOI: 10.7270/Q2T72JMX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM50403754 (CHEMBL164612) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research Foundation Curated by ChEMBL | Assay Description Binding affinity at human Alpha-2B adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement. | Bioorg Med Chem Lett 10: 71-4 (2000) BindingDB Entry DOI: 10.7270/Q2T72JMX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM50403737 (CHEMBL165776) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research Foundation Curated by ChEMBL | Assay Description Binding affinity at human Alpha-2B adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement. | Bioorg Med Chem Lett 10: 71-4 (2000) BindingDB Entry DOI: 10.7270/Q2T72JMX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM50403749 (CHEMBL165181) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research Foundation Curated by ChEMBL | Assay Description Binding affinity at human Alpha-2B adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement. | Bioorg Med Chem Lett 10: 71-4 (2000) BindingDB Entry DOI: 10.7270/Q2T72JMX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM50019848 (2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research Foundation Curated by ChEMBL | Assay Description Binding affinity at human Alpha-2B adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement. | Bioorg Med Chem Lett 10: 71-4 (2000) BindingDB Entry DOI: 10.7270/Q2T72JMX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM50403741 (CHEMBL165677) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 79 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research Foundation Curated by ChEMBL | Assay Description Binding affinity at human Alpha-2B adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement. | Bioorg Med Chem Lett 10: 71-4 (2000) BindingDB Entry DOI: 10.7270/Q2T72JMX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM50403743 (CHEMBL162058) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 195 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research Foundation Curated by ChEMBL | Assay Description Binding affinity at human Alpha-2B adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement. | Bioorg Med Chem Lett 10: 71-4 (2000) BindingDB Entry DOI: 10.7270/Q2T72JMX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM50115644 ((+/-)-12-Methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-tri...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 224 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research Foundation Curated by ChEMBL | Assay Description Binding affinity at human Alpha-2B adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement. | Bioorg Med Chem Lett 10: 71-4 (2000) BindingDB Entry DOI: 10.7270/Q2T72JMX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM626148 (US11786528, Example 35) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 530 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM626022 (US11786528, Example 11) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 580 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (NEONATAL RAT) | BDBM50083342 (7-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-4H-be...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 630 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company Curated by ChEMBL | Assay Description Inhibition of [3H]- Yohimbine binding against rat kidney cortex Alpha-2B adrenergic receptor | J Med Chem 42: 5181-7 (2000) BindingDB Entry DOI: 10.7270/Q23T9HZ0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM626015 (US11786528, Example 10) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 690 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM50244809 ((2R)-2-[3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(triflu...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 770 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of radioligand from adrenergic alpha2B receptor | Bioorg Med Chem Lett 18: 4798-801 (2008) Article DOI: 10.1016/j.bmcl.2008.07.103 BindingDB Entry DOI: 10.7270/Q2BC3ZC5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM50511341 (CHEMBL4483761) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 790 | n/a | n/a | n/a | n/a | n/a | n/a |
Division of Janssen-Cilag S.A. Curated by ChEMBL | Assay Description Displacement of [3H]RX 821002 from human recombinant adrenergic alpha-2B receptor expressed in CHO cells | ACS Med Chem Lett 11: 303-308 (2020) Article DOI: 10.1021/acsmedchemlett.9b00350 BindingDB Entry DOI: 10.7270/Q2GB27DF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM50065660 (CHEMBL3403995) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma AG Curated by ChEMBL | Assay Description Inhibition of alpha-adrenoceptor 2B (unknown origin) | Bioorg Med Chem Lett 25: 1787-91 (2015) Article DOI: 10.1016/j.bmcl.2015.02.040 BindingDB Entry DOI: 10.7270/Q2RF5WPJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM50174702 ((R)-N-(2-(3-(4-(4-fluorobenzyl)-2-methylpiperazin-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of human adrenergic alpha-2B receptor | Bioorg Med Chem Lett 15: 5160-4 (2005) Article DOI: 10.1016/j.bmcl.2005.08.057 BindingDB Entry DOI: 10.7270/Q2C53MMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM626057 (US11786528, Example 19) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 1.45E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM626180 (US11786528, Example 40) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 1.46E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM625944 (2-[(3-methylphenyl)methyl]-6-(1,2-thiazol-3-yl)-2H...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | MCE PC cid PC sid UniChem | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM50092139 (CHEMBL3582472) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.49E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of adrenergic alpha-2B receptor (unknown origin) | ACS Med Chem Lett 6: 573-8 (2015) Article DOI: 10.1021/acsmedchemlett.5b00054 BindingDB Entry DOI: 10.7270/Q2K64KT8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM625941 (US11786528, Comparative Example 1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 4.91E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM50319673 (1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Siena Biotech SpA Curated by ChEMBL | Assay Description Binding affinity to adrenergic alpha2B receptor | J Med Chem 53: 4379-89 (2010) Article DOI: 10.1021/jm901692q BindingDB Entry DOI: 10.7270/Q2S46S4Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM50240277 (CHEMBL4061793) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Discovery Chemistry Merck& Co. Curated by ChEMBL | Assay Description Antagonist activity at human alpha2B-adrenergic receptor | Bioorg Med Chem Lett 27: 2087-2093 (2017) Article DOI: 10.1016/j.bmcl.2017.03.085 BindingDB Entry DOI: 10.7270/Q29025XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM626028 (US11786528, Example 12) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM50304075 (3-(5-(4-tert-butylphenyl)-3-((dimethylamino)methyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School and the Informatics Institute of UMDNJ Curated by ChEMBL | Assay Description Inhibition of alpha2B adrenergic receptor | Bioorg Med Chem 17: 6442-50 (2009) Article DOI: 10.1016/j.bmc.2009.07.007 BindingDB Entry DOI: 10.7270/Q2QZ2B14 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM50318666 ((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute Curated by ChEMBL | Assay Description Binding affinity to human recombinant alpha2b receptor | Science 329: 1175-80 (2010) Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM50212239 (5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H](-)CGP-12177 from adrenergic beta2 receptor | Proc Natl Acad Sci USA 104: 8520-5 (2007) Article DOI: 10.1073/pnas.0611364104 BindingDB Entry DOI: 10.7270/Q2J10411 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM626170 (US11786528, Example 38) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 1.17E+4 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM626100 (US11786528, Example 24) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 2.56E+4 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM50401271 (CHEMBL2203713 | CHEMBL3216328) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NeurAxon Inc. Curated by ChEMBL | Assay Description Inhibition of alpha2B adrenergic receptor | Eur J Med Chem 55: 94-107 (2012) Article DOI: 10.1016/j.ejmech.2012.07.006 BindingDB Entry DOI: 10.7270/Q2GQ6ZWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM626206 (US11786528, Example 46) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair |