Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50346951 (CHEMBL1795711 | CHEMBL1795714) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 0.0270 | n/a | n/a | n/a | n/a | n/a |
Memorial Sloan-Kettering Cancer Center Curated by ChEMBL | Assay Description Binding affinity to KOR-1 expressed in CHO cells after 90 mins | Bioorg Med Chem Lett 21: 4001-4 (2011) Article DOI: 10.1016/j.bmcl.2011.05.008 BindingDB Entry DOI: 10.7270/Q29C6ZDF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50001714 (2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(1S,2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 0.0290 | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Dissociation constant against wild type EL-2 Opioid receptor kappa 1 expressed in HEK cells | J Med Chem 43: 1251-2 (2001) BindingDB Entry DOI: 10.7270/Q270824F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50001714 (2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(1S,2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 0.0380 | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Dissociation constant against E203Q,D204N,D206N,E209Q EL-2 Opioid receptor kappa 1 expressed in HEK cells | J Med Chem 43: 1251-2 (2001) BindingDB Entry DOI: 10.7270/Q270824F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50001714 (2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(1S,2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 0.0500 | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Dissociation constant against D216N,D217N,E218Q EL-2 Opioid receptor kappa 1 expressed in HEK cells | J Med Chem 43: 1251-2 (2001) BindingDB Entry DOI: 10.7270/Q270824F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50346952 (CHEMBL1795712 | CHEMBL1795715) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 0.0500 | n/a | n/a | n/a | n/a | n/a |
Memorial Sloan-Kettering Cancer Center Curated by ChEMBL | Assay Description Binding affinity to KOR-1 expressed in CHO cells after 90 mins | Bioorg Med Chem Lett 21: 4001-4 (2011) Article DOI: 10.1016/j.bmcl.2011.05.008 BindingDB Entry DOI: 10.7270/Q29C6ZDF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50001714 (2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(1S,2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 0.0500 | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Dissociation constant against E203Q,D204N,D206N EL-2 Opioid receptor kappa 1 expressed in HEK cells | J Med Chem 43: 1251-2 (2001) BindingDB Entry DOI: 10.7270/Q270824F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50021328 (3-Cyclopropylmethyl-11-ethyl-8-hydroxy-6-methyl-3,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for Opioid receptor kappa 1 affinity against the receptor site model site 4(kappa) | J Med Chem 29: 531-7 (1986) BindingDB Entry DOI: 10.7270/Q2WH2QKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50491417 (22-THIOCYANATOSALVINORIN A) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 0.590 | n/a | n/a | n/a | n/a | n/a |
University of Catania Curated by ChEMBL | Assay Description Binding affinity to kappa opioid receptor (unknown origin) | Eur J Med Chem 183: (2019) Article DOI: 10.1016/j.ejmech.2019.111701 BindingDB Entry DOI: 10.7270/Q2668HN9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50000788 ((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for Opioid receptor kappa 1 affinity against the receptor site model site 4(kappa) | J Med Chem 29: 531-7 (1986) BindingDB Entry DOI: 10.7270/Q2WH2QKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM21130 (N-methyl-2-phenyl-N-[(5R,7S,8S)-7-(pyrrolidin-1-yl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a |
University of Kansas Specialized Chemistry Center Curated by ChEMBL | Assay Description Binding affinity to rat kappa opioid receptor expressed in HEK293 cell membranes | Bioorg Med Chem 23: 3948-56 (2015) Article DOI: 10.1016/j.bmc.2014.12.033 BindingDB Entry DOI: 10.7270/Q2R49SJX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50001714 (2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(1S,2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 1.10 | n/a | n/a | n/a | 7.4 | 25 |
University of North Carolina School of Medicine | Assay Description Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar... | J Biol Chem 288: 34470-83 (2013) Article DOI: 10.1074/jbc.M113.515668 BindingDB Entry DOI: 10.7270/Q2P849RP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Mus musculus (Mouse)) | BDBM82551 (C18130 | CAS_105618-26-6 | NOR-BNI (HCI)2 | NORBNI) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.65 | n/a | n/a | n/a | n/a | n/a |
University of Washington Curated by ChEMBL | Assay Description Displacement of [3H]U69,593 from kappa opioid receptor in mouse brain tissue | J Biol Chem 282: 29803-11 (2007) Article DOI: 10.1074/jbc.M705540200 BindingDB Entry DOI: 10.7270/Q2MS3TNQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50528964 (CHEMBL4464797) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a |
University of Catania Curated by ChEMBL | Assay Description Binding affinity to kappa opioid receptor (unknown origin) | Eur J Med Chem 183: (2019) Article DOI: 10.1016/j.ejmech.2019.111701 BindingDB Entry DOI: 10.7270/Q2668HN9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50035471 (2-(3,4-Dichloro-phenyl)-N-[(S)-1-(3-isothiocyanato...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Tested for competitive covalent binding of compound against k opioid receptor in guinea pig brain membrane using [3H]-U-69,593 as radioligand | J Med Chem 37: 4490-8 (1995) BindingDB Entry DOI: 10.7270/Q2MW2G5Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50035476 (CHEMBL413530 | N-[(S)-1-(3-Amino-phenyl)-2-pyrroli...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Tested for competitive covalent binding of compound against k opioid receptor in guinea pig brain membrane; using [3H]-U-69,593 as radioligand | J Med Chem 37: 4490-8 (1995) BindingDB Entry DOI: 10.7270/Q2MW2G5Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM21130 (N-methyl-2-phenyl-N-[(5R,7S,8S)-7-(pyrrolidin-1-yl...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Binding affinity at Opioid receptor kappa 1 in guinea pig brain membrane determined by using [3H]U-69593 as radioligand | J Med Chem 31: 2015-21 (1988) BindingDB Entry DOI: 10.7270/Q2KP82Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50000788 ((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 4.5 | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd. Curated by ChEMBL | Assay Description Inhibition against binding of radioligand [N-allyl-2-3-3H]-naloxone to membrane of baby hamster kidney cells infected with forest virus encoding the... | Bioorg Med Chem Lett 10: 831-4 (2000) BindingDB Entry DOI: 10.7270/Q2N29XG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50511257 (CHEMBL4577693) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a |
Julius Maximilian University of W£rzburg Curated by ChEMBL | Assay Description Binding affinity to recombinant human KOR transiently expressed in CHOK1 cells measured after 20 mins by TIRF microscopic analysis | J Med Chem 63: 3596-3609 (2020) Article DOI: 10.1021/acs.jmedchem.9b02011 BindingDB Entry DOI: 10.7270/Q2445QTK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50511255 (CHEMBL4463414) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 9.5 | n/a | n/a | n/a | n/a | n/a |
Julius Maximilian University of W£rzburg Curated by ChEMBL | Assay Description Binding affinity to recombinant human KOR transiently expressed in CHOK1 cells measured after 20 mins by TIRF microscopic analysis | J Med Chem 63: 3596-3609 (2020) Article DOI: 10.1021/acs.jmedchem.9b02011 BindingDB Entry DOI: 10.7270/Q2445QTK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50511259 (CHEMBL4459592) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a |
Julius Maximilian University of W£rzburg Curated by ChEMBL | Assay Description Binding affinity to recombinant human KOR transiently expressed in CHOK1 cells measured after 20 mins by TIRF microscopic analysis | J Med Chem 63: 3596-3609 (2020) Article DOI: 10.1021/acs.jmedchem.9b02011 BindingDB Entry DOI: 10.7270/Q2445QTK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50021324 (3-(1-Cyclopropylmethyl-3-methyl-piperidin-3-yl)-ph...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Opioid receptor affinity against Opioid receptor kappa 1 by using the curve-fitting program LIGAND | J Med Chem 29: 531-7 (1986) BindingDB Entry DOI: 10.7270/Q2WH2QKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50021324 (3-(1-Cyclopropylmethyl-3-methyl-piperidin-3-yl)-ph...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Opioid receptor affinity against Opioid receptor kappa 1 by using the curve-fitting program LIGAND | J Med Chem 29: 531-7 (1986) BindingDB Entry DOI: 10.7270/Q2WH2QKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50019093 (1-Cyclopropylmethyl-3-(3-hydroxy-phenyl)-piperidin...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Binding affinity at Opioid receptor kappa 1 in guinea pig brain membrane determined by using [3H]U-69593 as radioligand | J Med Chem 31: 2015-21 (1988) BindingDB Entry DOI: 10.7270/Q2KP82Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50021323 (3-(1-Allyl-3-methyl-piperidin-3-yl)-phenol | 3-(1-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 137 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Opioid receptor affinity against Opioid receptor kappa 1 by using the curve-fitting program LIGAND | J Med Chem 29: 531-7 (1986) BindingDB Entry DOI: 10.7270/Q2WH2QKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50021323 (3-(1-Allyl-3-methyl-piperidin-3-yl)-phenol | 3-(1-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 137 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Opioid receptor affinity against Opioid receptor kappa 1 by using the curve-fitting program LIGAND | J Med Chem 29: 531-7 (1986) BindingDB Entry DOI: 10.7270/Q2WH2QKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50021322 (3-(3-Methyl-1-phenethyl-piperidin-3-yl)-phenol | 3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 179 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Opioid receptor affinity against Opioid receptor kappa 1 by using the curve-fitting program LIGAND | J Med Chem 29: 531-7 (1986) BindingDB Entry DOI: 10.7270/Q2WH2QKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50021322 (3-(3-Methyl-1-phenethyl-piperidin-3-yl)-phenol | 3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 179 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Opioid receptor affinity against Opioid receptor kappa 1 by using the curve-fitting program LIGAND | J Med Chem 29: 531-7 (1986) BindingDB Entry DOI: 10.7270/Q2WH2QKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50019094 (1-Allyl-3-(3-hydroxy-phenyl)-piperidine-3-carboxyl...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Binding affinity at Opioid receptor kappa 1 in guinea pig brain membrane determined by using [3H]U-69593 as radioligand | J Med Chem 31: 2015-21 (1988) BindingDB Entry DOI: 10.7270/Q2KP82Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM21015 ((2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 509 | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Binding affinity against kappa opioid receptor using [35S]GTP-gamma-S, binding assay in guinea pig caudate membranes blocked with 6 nM nor-BNI | Bioorg Med Chem Lett 9: 3347-50 (2000) BindingDB Entry DOI: 10.7270/Q2MK6DDP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM21015 ((2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 509 | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Binding affinity against kappa opioid receptor using [35S]GTP-gamma-S, binding assay in guinea pig caudate membranes blocked with 6 nM nor-BNI | Bioorg Med Chem Lett 9: 3053-6 (1999) BindingDB Entry DOI: 10.7270/Q28916BJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM21025 ((2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydro...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 625 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for Opioid receptor kappa 1 affinity against the receptor site model site 4(kappa) | J Med Chem 29: 531-7 (1986) BindingDB Entry DOI: 10.7270/Q2WH2QKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50021327 (3-(1,3-Dimethyl-piperidin-3-yl)-phenol | 3-(1,3-Di...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 625 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Opioid receptor affinity against Opioid receptor kappa 1 by using the curve-fitting program LIGAND | J Med Chem 29: 531-7 (1986) BindingDB Entry DOI: 10.7270/Q2WH2QKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50021327 (3-(1,3-Dimethyl-piperidin-3-yl)-phenol | 3-(1,3-Di...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 625 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Opioid receptor affinity against Opioid receptor kappa 1 by using the curve-fitting program LIGAND | J Med Chem 29: 531-7 (1986) BindingDB Entry DOI: 10.7270/Q2WH2QKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50039029 ((+)-4-((alpha R)-((2S,5R)-4-allyl-2,5-dimethylpipe...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 629 | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Binding affinity against kappa opioid receptor using [35S]GTP-gamma-S, binding assay in guinea pig caudate membranes blocked with 6 nM nor-BNI | Bioorg Med Chem Lett 9: 3053-6 (1999) BindingDB Entry DOI: 10.7270/Q28916BJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50019097 (1-Cyclopropylmethyl-3-(3-hydroxy-phenyl)-2-methyl-...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 830 | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Binding affinity at Opioid receptor kappa 1 in guinea pig brain membrane determined by using [3H]U-69593 as radioligand | J Med Chem 31: 2015-21 (1988) BindingDB Entry DOI: 10.7270/Q2KP82Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50019095 (1-Allyl-3-(3-hydroxy-phenyl)-2-methyl-piperidine-3...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 830 | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Binding affinity at Opioid receptor kappa 1 in guinea pig brain membrane determined by using [3H]U-69593 as radioligand | J Med Chem 31: 2015-21 (1988) BindingDB Entry DOI: 10.7270/Q2KP82Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50452273 (Dihydromorphine) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 830 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for Opioid receptor kappa 1 affinity against the receptor site model site 4(kappa) | J Med Chem 29: 531-7 (1986) BindingDB Entry DOI: 10.7270/Q2WH2QKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50019098 (3-(3-Hydroxy-phenyl)-1,2-dimethyl-piperidine-3-car...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Binding affinity at Opioid receptor kappa 1 in guinea pig brain membrane determined by using [3H]U-69593 as radioligand | J Med Chem 31: 2015-21 (1988) BindingDB Entry DOI: 10.7270/Q2KP82Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50019092 (3-(3-Hydroxy-phenyl)-1-methyl-piperidine-3-carboxy...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Binding affinity at Opioid receptor kappa 1 in guinea pig brain membrane determined by using [3H]U-69593 as radioligand | J Med Chem 31: 2015-21 (1988) BindingDB Entry DOI: 10.7270/Q2KP82Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50019091 (3-(3-Hydroxy-phenyl)-2-methyl-1-phenethyl-piperidi...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Binding affinity at Opioid receptor kappa 1 in guinea pig brain membrane determined by using [3H]U-69593 as radioligand | J Med Chem 31: 2015-21 (1988) BindingDB Entry DOI: 10.7270/Q2KP82Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50082341 (4-[((3R,4S)-1-Allyl-3-methyl-piperidin-4-yl)-pheny...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 2.95E+3 | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Binding affinity against kappa opioid receptor using [35S]GTP-gamma-S, binding assay in guinea pig caudate membranes blocked with 6 nM nor-BNI | Bioorg Med Chem Lett 9: 3347-50 (2000) BindingDB Entry DOI: 10.7270/Q2MK6DDP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50082339 (4-[((S)-1-Allyl-3-methyl-piperidin-4-yl)-phenyl-am...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 3.72E+3 | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Binding affinity against kappa opioid receptor using [35S]GTP-gamma-S, binding assay in guinea pig caudate membranes blocked with 6 nM nor-BNI | Bioorg Med Chem Lett 9: 3053-6 (1999) BindingDB Entry DOI: 10.7270/Q28916BJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50083636 (4-[(1-Allyl-3-methyl-piperidin-4-yl)-phenyl-amino]...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 3.72E+3 | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Binding affinity against kappa opioid receptor using [35S]GTP-gamma-S, binding assay in guinea pig caudate membranes blocked with 6 nM nor-BNI | Bioorg Med Chem Lett 9: 3347-50 (2000) BindingDB Entry DOI: 10.7270/Q2MK6DDP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM21130 (N-methyl-2-phenyl-N-[(5R,7S,8S)-7-(pyrrolidin-1-yl...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 4.89E+3 | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Binding affinity against Mu opioid receptor using [35S]GTP-gamma-S, binding assay in guinea pig caudate membranes blocked with 6000 nM CTAP | Bioorg Med Chem Lett 9: 3347-50 (2000) BindingDB Entry DOI: 10.7270/Q2MK6DDP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM21130 (N-methyl-2-phenyl-N-[(5R,7S,8S)-7-(pyrrolidin-1-yl...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 4.89E+3 | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Binding affinity against Delta opioid receptor in using [35S]GTP-gamma-S, binding assay in guinea pig caudate membranes blocked with 20 nM NTI | Bioorg Med Chem Lett 9: 3053-6 (1999) BindingDB Entry DOI: 10.7270/Q28916BJ | |||||||||||
More data for this Ligand-Target Pair |