Compile Data Set for Download or QSAR

Found 580 hits Enz. Inhib. hit(s) with Target = 'Polymerase acidic protein'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polymerase acidic protein (Hepatitis C virus)	BDBM50509167 (CHEMBL4539596) Show SMILES CCc1ccccc1-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C14H13NO4/c1-2-8-5-3-4-6-9(8)10-7-11(16)13(17)12(15-10)14(18)19/h3-7,17H,2H2,1H3,(H,15,16)(H,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	<2	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair				3D Structure (crystal)
Polymerase acidic protein (Hepatitis C virus)	BDBM50509167 (CHEMBL4539596) Show SMILES CCc1ccccc1-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C14H13NO4/c1-2-8-5-3-4-6-9(8)10-7-11(16)13(17)12(15-10)14(18)19/h3-7,17H,2H2,1H3,(H,15,16)(H,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	>2	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair				3D Structure (crystal)
Polymerase acidic protein (Hepatitis C virus)	BDBM50509165 (CHEMBL4459575) Show SMILES OC(=O)c1ccc(cc1)-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C13H9NO6/c15-9-5-8(14-10(11(9)16)13(19)20)6-1-3-7(4-2-6)12(17)18/h1-5,16H,(H,14,15)(H,17,18)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509159 (CHEMBL4588964) Show SMILES OC(=O)c1[nH]c(cc(=O)c1O)-c1ccccc1C(F)(F)F Show InChI InChI=1S/C13H8F3NO4/c14-13(15,16)7-4-2-1-3-6(7)8-5-9(18)11(19)10(17-8)12(20)21/h1-5,19H,(H,17,18)(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<2	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509161 (CHEMBL4563716) Show SMILES OC(=O)c1[nH]c(cc(=O)c1O)-c1cccc(c1)-c1nnn[nH]1 Show InChI InChI=1S/C13H9N5O4/c19-9-5-8(14-10(11(9)20)13(21)22)6-2-1-3-7(4-6)12-15-17-18-16-12/h1-5,20H,(H,14,19)(H,21,22)(H,15,16,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	<2	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair				3D Structure (crystal)
Polymerase acidic protein (Hepatitis C virus)	BDBM50509169 (CHEMBL4545631) Show SMILES Cc1ccccc1-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C13H11NO4/c1-7-4-2-3-5-8(7)9-6-10(15)12(16)11(14-9)13(17)18/h2-6,16H,1H3,(H,14,15)(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	>2	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair				3D Structure (crystal)
Polymerase acidic protein (Hepatitis C virus)	BDBM50509169 (CHEMBL4545631) Show SMILES Cc1ccccc1-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C13H11NO4/c1-7-4-2-3-5-8(7)9-6-10(15)12(16)11(14-9)13(17)18/h2-6,16H,1H3,(H,14,15)(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	<2	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair				3D Structure (crystal)
Polymerase acidic protein (Hepatitis C virus)	BDBM50509165 (CHEMBL4459575) Show SMILES OC(=O)c1ccc(cc1)-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C13H9NO6/c15-9-5-8(14-10(11(9)16)13(19)20)6-1-3-7(4-2-6)12(17)18/h1-5,16H,(H,14,15)(H,17,18)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<2	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509161 (CHEMBL4563716) Show SMILES OC(=O)c1[nH]c(cc(=O)c1O)-c1cccc(c1)-c1nnn[nH]1 Show InChI InChI=1S/C13H9N5O4/c19-9-5-8(14-10(11(9)20)13(21)22)6-2-1-3-7(4-6)12-15-17-18-16-12/h1-5,20H,(H,14,19)(H,21,22)(H,15,16,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	>2	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair				3D Structure (crystal)
Polymerase acidic protein (Hepatitis C virus)	BDBM50509155 (CHEMBL4440123) Show SMILES OC(=O)c1[nH]c(cc(=O)c1O)-c1ccc(cc1)-c1nnn[nH]1 Show InChI InChI=1S/C13H9N5O4/c19-9-5-8(14-10(11(9)20)13(21)22)6-1-3-7(4-2-6)12-15-17-18-16-12/h1-5,20H,(H,14,19)(H,21,22)(H,15,16,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509159 (CHEMBL4588964) Show SMILES OC(=O)c1[nH]c(cc(=O)c1O)-c1ccccc1C(F)(F)F Show InChI InChI=1S/C13H8F3NO4/c14-13(15,16)7-4-2-1-3-6(7)8-5-9(18)11(19)10(17-8)12(20)21/h1-5,19H,(H,17,18)(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509155 (CHEMBL4440123) Show SMILES OC(=O)c1[nH]c(cc(=O)c1O)-c1ccc(cc1)-c1nnn[nH]1 Show InChI InChI=1S/C13H9N5O4/c19-9-5-8(14-10(11(9)20)13(21)22)6-1-3-7(4-2-6)12-15-17-18-16-12/h1-5,20H,(H,14,19)(H,21,22)(H,15,16,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<2	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509160 (CHEMBL4570983) Show SMILES COc1ccccc1-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C13H11NO5/c1-19-10-5-3-2-4-7(10)8-6-9(15)12(16)11(14-8)13(17)18/h2-6,16H,1H3,(H,14,15)(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509170 (CHEMBL4440338) Show SMILES OC(=O)c1cccc(c1)-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C13H9NO6/c15-9-5-8(14-10(11(9)16)13(19)20)6-2-1-3-7(4-6)12(17)18/h1-5,16H,(H,14,15)(H,17,18)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair				3D Structure (crystal)
Polymerase acidic protein (Hepatitis C virus)	BDBM50509160 (CHEMBL4570983) Show SMILES COc1ccccc1-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C13H11NO5/c1-19-10-5-3-2-4-7(10)8-6-9(15)12(16)11(14-8)13(17)18/h2-6,16H,1H3,(H,14,15)(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50612273 (BALOXAVIR | Baloxavir | S-033447) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	UniChem		n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509170 (CHEMBL4440338) Show SMILES OC(=O)c1cccc(c1)-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C13H9NO6/c15-9-5-8(14-10(11(9)16)13(19)20)6-2-1-3-7(4-6)12(17)18/h1-5,16H,(H,14,15)(H,17,18)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair				3D Structure (crystal)
Polymerase acidic protein (Hepatitis C virus)	BDBM50509157 (CHEMBL4530222) Show SMILES CC(C)c1ccccc1-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C15H15NO4/c1-8(2)9-5-3-4-6-10(9)11-7-12(17)14(18)13(16-11)15(19)20/h3-8,18H,1-2H3,(H,16,17)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509166 (CHEMBL4550646) Show SMILES CSc1ccccc1-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C13H11NO4S/c1-19-10-5-3-2-4-7(10)8-6-9(15)12(16)11(14-8)13(17)18/h2-6,16H,1H3,(H,14,15)(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509166 (CHEMBL4550646) Show SMILES CSc1ccccc1-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C13H11NO4S/c1-19-10-5-3-2-4-7(10)8-6-9(15)12(16)11(14-8)13(17)18/h2-6,16H,1H3,(H,14,15)(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509157 (CHEMBL4530222) Show SMILES CC(C)c1ccccc1-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C15H15NO4/c1-8(2)9-5-3-4-6-10(9)11-7-12(17)14(18)13(16-11)15(19)20/h3-8,18H,1-2H3,(H,16,17)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509172 (CHEMBL4553243) Show SMILES Cc1cccc(c1)-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C13H11NO4/c1-7-3-2-4-8(5-7)9-6-10(15)12(16)11(14-9)13(17)18/h2-6,16H,1H3,(H,14,15)(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50508967 (CHEMBL3944613) Show SMILES OC(=O)c1cn(CC2(CCCC2)n2ccc3cccnc23)cc(O)c1=O Show InChI InChI=1S/C19H19N3O4/c23-15-11-21(10-14(16(15)24)18(25)26)12-19(6-1-2-7-19)22-9-5-13-4-3-8-20-17(13)22/h3-5,8-11,23H,1-2,6-7,12H2,(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Company Curated by ChEMBL					Assay Description Inhibition of Influenza A virus CEN				J Med Chem 62: 8101-8114 (2019) Article DOI: 10.1021/acs.jmedchem.9b00861 BindingDB Entry DOI: 10.7270/Q2K35XZJ
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509172 (CHEMBL4553243) Show SMILES Cc1cccc(c1)-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C13H11NO4/c1-7-3-2-4-8(5-7)9-6-10(15)12(16)11(14-9)13(17)18/h2-6,16H,1H3,(H,14,15)(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509173 (CHEMBL4469796) Show SMILES OC(=O)c1[nH]c(cc(=O)c1O)-c1ccccc1 Show InChI InChI=1S/C12H9NO4/c14-9-6-8(7-4-2-1-3-5-7)13-10(11(9)15)12(16)17/h1-6,15H,(H,13,14)(H,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509173 (CHEMBL4469796) Show SMILES OC(=O)c1[nH]c(cc(=O)c1O)-c1ccccc1 Show InChI InChI=1S/C12H9NO4/c14-9-6-8(7-4-2-1-3-5-7)13-10(11(9)15)12(16)17/h1-6,15H,(H,13,14)(H,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509168 (CHEMBL4460007) Show SMILES OC(=O)c1[nH]c(cc(=O)c1O)-c1ccccc1Oc1ccccc1 Show InChI InChI=1S/C18H13NO5/c20-14-10-13(19-16(17(14)21)18(22)23)12-8-4-5-9-15(12)24-11-6-2-1-3-7-11/h1-10,21H,(H,19,20)(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509154 (CHEMBL4453833) Show SMILES CC(C)c1cccc(c1)-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C15H15NO4/c1-8(2)9-4-3-5-10(6-9)11-7-12(17)14(18)13(16-11)15(19)20/h3-8,18H,1-2H3,(H,16,17)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509154 (CHEMBL4453833) Show SMILES CC(C)c1cccc(c1)-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C15H15NO4/c1-8(2)9-4-3-5-10(6-9)11-7-12(17)14(18)13(16-11)15(19)20/h3-8,18H,1-2H3,(H,16,17)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509168 (CHEMBL4460007) Show SMILES OC(=O)c1[nH]c(cc(=O)c1O)-c1ccccc1Oc1ccccc1 Show InChI InChI=1S/C18H13NO5/c20-14-10-13(19-16(17(14)21)18(22)23)12-8-4-5-9-15(12)24-11-6-2-1-3-7-11/h1-10,21H,(H,19,20)(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509152 (CHEMBL4535893) Show SMILES Cc1ccc(cc1)-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C13H11NO4/c1-7-2-4-8(5-3-7)9-6-10(15)12(16)11(14-9)13(17)18/h2-6,16H,1H3,(H,14,15)(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509152 (CHEMBL4535893) Show SMILES Cc1ccc(cc1)-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C13H11NO4/c1-7-2-4-8(5-3-7)9-6-10(15)12(16)11(14-9)13(17)18/h2-6,16H,1H3,(H,14,15)(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474361 ((S)-6-benzhydryl-11-hydroxy-3-(1H-pyrazol- 4-yl)-5...) Show SMILES Oc1c2-c3ncc(-c4cn[nH]c4)n3C[C@H](C(c3ccccc3)c3ccccc3)n2ccc1=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474361 ((S)-6-benzhydryl-11-hydroxy-3-(1H-pyrazol- 4-yl)-5...) Show SMILES Oc1c2-c3ncc(-c4cn[nH]c4)n3C[C@H](C(c3ccccc3)c3ccccc3)n2ccc1=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z60S8G
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474346 ((S)-6-benzhydryl-3-bromo-11-hydroxy-5H- imidazo[1,...) Show SMILES Oc1c2-c3ncc(Br)n3C[C@H](C(c3ccccc3)c3ccccc3)n2ccc1=O |r| Show InChI InChI=1S/C23H18BrN3O2/c24-19-13-25-23-21-22(29)18(28)11-12-26(21)17(14-27(19)23)20(15-7-3-1-4-8-15)16-9-5-2-6-10-16/h1-13,17,20,29H,14H2/t17-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z60S8G
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474354 ((S)-6-((S)-(3-fluorophenyl)(4- fluorophenyl)methyl...) Show SMILES Oc1c2-c3nccn3C[C@H]([C@@H](c3ccc(F)cc3)c3cccc(F)c3)n2ncc1=O |r| Show InChI InChI=1S/C22H16F2N4O2/c23-15-6-4-13(5-7-15)19(14-2-1-3-16(24)10-14)17-12-27-9-8-25-22(27)20-21(30)18(29)11-26-28(17)20/h1-11,17,19,30H,12H2/t17-,19+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z60S8G
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474346 ((S)-6-benzhydryl-3-bromo-11-hydroxy-5H- imidazo[1,...) Show SMILES Oc1c2-c3ncc(Br)n3C[C@H](C(c3ccccc3)c3ccccc3)n2ccc1=O |r| Show InChI InChI=1S/C23H18BrN3O2/c24-19-13-25-23-21-22(29)18(28)11-12-26(21)17(14-27(19)23)20(15-7-3-1-4-8-15)16-9-5-2-6-10-16/h1-13,17,20,29H,14H2/t17-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474354 ((S)-6-((S)-(3-fluorophenyl)(4- fluorophenyl)methyl...) Show SMILES Oc1c2-c3nccn3C[C@H]([C@@H](c3ccc(F)cc3)c3cccc(F)c3)n2ncc1=O |r| Show InChI InChI=1S/C22H16F2N4O2/c23-15-6-4-13(5-7-15)19(14-2-1-3-16(24)10-14)17-12-27-9-8-25-22(27)20-21(30)18(29)11-26-28(17)20/h1-11,17,19,30H,12H2/t17-,19+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474343 ((S)-6-Benzhydryl-11-hydroxy-5H- imidazo[1,2-a]pyri...) Show SMILES Oc1c2-c3nccn3C[C@H](C(c3ccccc3)c3ccccc3)n2ccc1=O |r| Show InChI InChI=1S/C23H19N3O2/c27-19-11-13-26-18(15-25-14-12-24-23(25)21(26)22(19)28)20(16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-14,18,20,28H,15H2/t18-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474343 ((S)-6-Benzhydryl-11-hydroxy-5H- imidazo[1,2-a]pyri...) Show SMILES Oc1c2-c3nccn3C[C@H](C(c3ccccc3)c3ccccc3)n2ccc1=O |r| Show InChI InChI=1S/C23H19N3O2/c27-19-11-13-26-18(15-25-14-12-24-23(25)21(26)22(19)28)20(16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-14,18,20,28H,15H2/t18-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z60S8G
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474367 ((S)-6-((S)-(3-bromophenyl)(4- fluorophenyl)methyl)...) Show SMILES Oc1c2-c3nccn3C[C@H]([C@@H](c3ccc(F)cc3)c3cccc(Br)c3)n2ncc1=O |r| Show InChI InChI=1S/C22H16BrFN4O2/c23-15-3-1-2-14(10-15)19(13-4-6-16(24)7-5-13)17-12-27-9-8-25-22(27)20-21(30)18(29)11-26-28(17)20/h1-11,17,19,30H,12H2/t17-,19+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z60S8G
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474357 ((S)-6-((R)-(2-bromo-4-fluorophenyl)(4- fluoropheny...) Show SMILES Oc1c2-c3nccn3C[C@H]([C@H](c3ccc(F)cc3)c3ccc(F)cc3Br)n2ncc1=O |r| Show InChI InChI=1S/C22H15BrF2N4O2/c23-16-9-14(25)5-6-15(16)19(12-1-3-13(24)4-2-12)17-11-28-8-7-26-22(28)20-21(31)18(30)10-27-29(17)20/h1-10,17,19,31H,11H2/t17-,19-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z60S8G
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474367 ((S)-6-((S)-(3-bromophenyl)(4- fluorophenyl)methyl)...) Show SMILES Oc1c2-c3nccn3C[C@H]([C@@H](c3ccc(F)cc3)c3cccc(Br)c3)n2ncc1=O |r| Show InChI InChI=1S/C22H16BrFN4O2/c23-15-3-1-2-14(10-15)19(13-4-6-16(24)7-5-13)17-12-27-9-8-25-22(27)20-21(30)18(29)11-26-28(17)20/h1-11,17,19,30H,12H2/t17-,19+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474357 ((S)-6-((R)-(2-bromo-4-fluorophenyl)(4- fluoropheny...) Show SMILES Oc1c2-c3nccn3C[C@H]([C@H](c3ccc(F)cc3)c3ccc(F)cc3Br)n2ncc1=O |r| Show InChI InChI=1S/C22H15BrF2N4O2/c23-16-9-14(25)5-6-15(16)19(12-1-3-13(24)4-2-12)17-11-28-8-7-26-22(28)20-21(31)18(30)10-27-29(17)20/h1-10,17,19,31H,11H2/t17-,19-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM105203 (6-(4-Fluorophenyl)-3-hydroxy-5-[4-(1H-1, 2, 3, 4-t...) Show SMILES Oc1cc(-c2ccc(cc2)-c2nnn[nH]2)c([nH]c1=O)-c1ccc(F)cc1 Show InChI InChI=1S/C18H12FN5O2/c19-13-7-5-11(6-8-13)16-14(9-15(25)18(26)20-16)10-1-3-12(4-2-10)17-21-23-24-22-17/h1-9,25H,(H,20,26)(H,21,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Chiba University Curated by ChEMBL					Assay Description Inhibition of Influenza A/Puerto Rico/8/34 (H1N1) PA N-terminal domain endonuclease activity expressed in Escherichia coli BL21 (RIL) cells using (6-...				Bioorg Med Chem 23: 5466-75 (2015) Article DOI: 10.1016/j.bmc.2015.07.046 BindingDB Entry DOI: 10.7270/Q2N87CK3
					More data for this Ligand-Target Pair
Polymerase acidic protein [1-204,T86I,G186S] (2009 H1N1 Influenza)	BDBM105203 (6-(4-Fluorophenyl)-3-hydroxy-5-[4-(1H-1, 2, 3, 4-t...) Show SMILES Oc1cc(-c2ccc(cc2)-c2nnn[nH]2)c([nH]c1=O)-c1ccc(F)cc1 Show InChI InChI=1S/C18H12FN5O2/c19-13-7-5-11(6-8-13)16-14(9-15(25)18(26)20-16)10-1-3-12(4-2-10)17-21-23-24-22-17/h1-9,25H,(H,20,26)(H,21,22,23,24)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Rutgers University					Assay Description Cocktails of 4-8 compounds were used for the initial screening with single compound soaks to verify the bound fragment identity and to rule out coope...				ACS Chem Biol 8: 2501-8 (2013) Article DOI: 10.1021/cb400400j BindingDB Entry DOI: 10.7270/Q28W3BZW
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM105203 (6-(4-Fluorophenyl)-3-hydroxy-5-[4-(1H-1, 2, 3, 4-t...) Show SMILES Oc1cc(-c2ccc(cc2)-c2nnn[nH]2)c([nH]c1=O)-c1ccc(F)cc1 Show InChI InChI=1S/C18H12FN5O2/c19-13-7-5-11(6-8-13)16-14(9-15(25)18(26)20-16)10-1-3-12(4-2-10)17-21-23-24-22-17/h1-9,25H,(H,20,26)(H,21,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Company Curated by ChEMBL					Assay Description Inhibition of Influenza A virus CEN				J Med Chem 62: 8101-8114 (2019) Article DOI: 10.1021/acs.jmedchem.9b00861 BindingDB Entry DOI: 10.7270/Q2K35XZJ
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50409783 (CHEMBL1626982 | CHEMBL2068710 | CHEMBL2068711 | CH...) Show SMILES [O-]C(=O)C(=O)[CH-]C(=O)C1(Cc2ccc(Cl)cc2)CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C23H23ClNO4/c24-19-8-6-17(7-9-19)15-23(21(27)14-20(26)22(28)29)10-12-25(13-11-23)16-18-4-2-1-3-5-18/h1-9,14H,10-13,15-16H2,(H,28,29)/q-1/p-1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Roche Discovery Welwyn Curated by ChEMBL					Assay Description Inhibitory concentration against cap-dependent endonuclease activity of influenza A/PR/8/34 RNP				J Med Chem 46: 1153-64 (2003) Article DOI: 10.1021/jm020334u BindingDB Entry DOI: 10.7270/Q22J6B6V
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509158 (CHEMBL4438546) Show SMILES OC(=O)c1[nH]c(cc(=O)c1O)-c1cccc(Oc2ccccc2)c1 Show InChI InChI=1S/C18H13NO5/c20-15-10-14(19-16(17(15)21)18(22)23)11-5-4-8-13(9-11)24-12-6-2-1-3-7-12/h1-10,21H,(H,19,20)(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50508966 (CHEMBL4452342) Show SMILES CN(Cc1cc(=O)c(O)cn1-c1ccc(cc1)-c1nnn[nH]1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H17ClN6O2/c1-26(15-8-4-14(21)5-9-15)11-17-10-18(28)19(29)12-27(17)16-6-2-13(3-7-16)20-22-24-25-23-20/h2-10,12,29H,11H2,1H3,(H,22,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of 8-histidine tagged influenza virus H1N1 N-terminal PA endonuclease expressed in Escherichia coli BL21 cells using single-stranded 5'-FA...				J Med Chem 59: 6444-54 (2016) Article DOI: 10.1021/acs.jmedchem.6b00628 BindingDB Entry DOI: 10.7270/Q2W95DPM
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 580 total )  |  Next  |  Last  >>

Jump to: