Compile Data Set for Download or QSAR

Found 26 hits Enz. Inhib. hit(s) with Target = 'Ectonucleoside triphosphate diphosphohydrolase 8'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ectonucleoside triphosphate diphosphohydrolase 8 (Homo sapiens (Human))	BDBM50029031 (1-Amino-4-{4-[4-chloro-6-(3-sulfo-phenylamino)-[1,...) Show SMILES Nc1c(cc(Nc2ccc(Nc3nc(Cl)nc(Nc4cccc(c4)S([O-])(=O)=O)n3)c(c2)S([O-])(=O)=O)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O Show InChI InChI=1S/C29H20ClN7O11S3/c30-27-35-28(33-13-4-3-5-15(10-13)49(40,41)42)37-29(36-27)34-18-9-8-14(11-20(18)50(43,44)45)32-19-12-21(51(46,47)48)24(31)23-22(19)25(38)16-6-1-2-7-17(16)26(23)39/h1-12,32H,31H2,(H,40,41,42)(H,43,44,45)(H,46,47,48)(H2,33,34,35,36,37)/p-3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human NTPDase 8 expressed in COS7 cells				J Med Chem 51: 4518-28 (2008) Article DOI: 10.1021/jm800175e BindingDB Entry DOI: 10.7270/Q2XW4KQX
					More data for this Ligand-Target Pair
Ectonucleoside triphosphate diphosphohydrolase 8 (Homo sapiens (Human))	BDBM50336799 (5,5',5''-[1,3,6-naphthalenetriyltris(sulfonylimino...) Show SMILES Cc1ccc(cc1NC(=O)c1cccc(NC(=O)Nc2cccc(c2)C(=O)Nc2cc(ccc2C)C(=O)Nc2ccc(c3cc(cc(c23)S(O)(=O)=O)S(O)(=O)=O)S(O)(=O)=O)c1)C(=O)Nc1ccc(c2cc(cc(c12)S(O)(=O)=O)S(O)(=O)=O)S(O)(=O)=O Show InChI InChI=1S/C51H40N6O23S6/c1-25-9-11-29(49(60)54-37-13-15-41(83(69,70)71)35-21-33(81(63,64)65)23-43(45(35)37)85(75,76)77)19-39(25)56-47(58)27-5-3-7-31(17-27)52-51(62)53-32-8-4-6-28(18-32)48(59)57-40-20-30(12-10-26(40)2)50(61)55-38-14-16-42(84(72,73)74)36-22-34(82(66,67)68)24-44(46(36)38)86(78,79)80/h3-24H,1-2H3,(H,54,60)(H,55,61)(H,56,58)(H,57,59)(H2,52,53,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human NTPDase 8 expressed in COS7 cells				J Med Chem 51: 4518-28 (2008) Article DOI: 10.1021/jm800175e BindingDB Entry DOI: 10.7270/Q2XW4KQX
					More data for this Ligand-Target Pair
Ectonucleoside triphosphate diphosphohydrolase 8 (Homo sapiens (Human))	BDBM50195359 (ARL-67156 | CHEMBL223145) Show SMILES CCN(CC)c1ncnc2n(cnc12)[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)C(Br)(Br)P([O-])([O-])=O)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C15H24Br2N5O12P3/c1-3-21(4-2)12-9-13(19-6-18-12)22(7-20-9)14-11(24)10(23)8(33-14)5-32-37(30,31)34-36(28,29)15(16,17)35(25,26)27/h6-8,10-11,14,23-24H,3-5H2,1-2H3,(H,28,29)(H,30,31)(H2,25,26,27)/p-4/t8-,10-,11-,14-/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human NTPDase 8 expressed in COS7 cells				J Med Chem 51: 4518-28 (2008) Article DOI: 10.1021/jm800175e BindingDB Entry DOI: 10.7270/Q2XW4KQX
					More data for this Ligand-Target Pair
Ectonucleoside triphosphate diphosphohydrolase 8 (Homo sapiens (Human))	BDBM50262251 (4-[4-((2S,3R,4S,5R)-5-(2,4-Dioxo-3,4-dihydropyrimi...) Show SMILES CCOP(=O)(Cc1ccc(NC(=O)CCCNC(=O)[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)cc1)OCC |r| Show InChI InChI=1S/C24H33N4O10P/c1-3-36-39(35,37-4-2)14-15-7-9-16(10-8-15)26-17(29)6-5-12-25-22(33)21-19(31)20(32)23(38-21)28-13-11-18(30)27-24(28)34/h7-11,13,19-21,23,31-32H,3-6,12,14H2,1-2H3,(H,25,33)(H,26,29)(H,27,30,34)/t19-,20+,21-,23+/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.42E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human NTPDase 8 expressed in COS7 cells				J Med Chem 51: 4518-28 (2008) Article DOI: 10.1021/jm800175e BindingDB Entry DOI: 10.7270/Q2XW4KQX
					More data for this Ligand-Target Pair
Ectonucleoside triphosphate diphosphohydrolase 8 (Homo sapiens (Human))	BDBM50262373 (4-[4-((2S,3R,4S,5R)-5-(6-Amino-9H-purin-9-yl)-3,4-...) Show SMILES CCOP(=O)(Cc1ccc(NC(=O)CCCNC(=O)[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cnc3c(N)ncnc23)cc1)OCC |r| Show InChI InChI=1S/C25H34N7O8P/c1-3-38-41(37,39-4-2)12-15-7-9-16(10-8-15)31-17(33)6-5-11-27-24(36)21-19(34)20(35)25(40-21)32-14-30-18-22(26)28-13-29-23(18)32/h7-10,13-14,19-21,25,34-35H,3-6,11-12H2,1-2H3,(H,27,36)(H,31,33)(H2,26,28,29)/t19-,20+,21-,25+/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.55E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human NTPDase 8 expressed in COS7 cells				J Med Chem 51: 4518-28 (2008) Article DOI: 10.1021/jm800175e BindingDB Entry DOI: 10.7270/Q2XW4KQX
					More data for this Ligand-Target Pair
Ectonucleoside triphosphate diphosphohydrolase 8 (Homo sapiens (Human))	BDBM50546288 (CHEMBL4743437) Show SMILES C[C@H](Nc1nc(Cl)nc2n(ncc12)[C@@H]1O[C@H](COP(O)(=O)CP(O)(O)=O)[C@@H](O)[C@H]1O)c1ccccc1 |r| Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of NTPDase 8 (unknown origin) expressed in CHO cells using ATP as substrate preincubated for 1 hr followed by substrate addition and measu...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00525 BindingDB Entry DOI: 10.7270/Q29W0K29
					More data for this Ligand-Target Pair
Ectonucleoside triphosphate diphosphohydrolase 8 (Homo sapiens (Human))	BDBM50546280 (CHEMBL4761506) Show SMILES C[C@H](Nc1cc(Cl)nc2n(ncc12)[C@@H]1O[C@H](COP(O)(=O)CP(O)(O)=O)[C@@H](O)[C@H]1O)c1ccc(F)cc1 |r| Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of NTPDase 8 (unknown origin) expressed in CHO cells using ATP as substrate preincubated for 1 hr followed by substrate addition and measu...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00525 BindingDB Entry DOI: 10.7270/Q29W0K29
					More data for this Ligand-Target Pair
Ectonucleoside triphosphate diphosphohydrolase 8 (Homo sapiens (Human))	BDBM50527134 (CHEMBL4471306 | US20230295213, Compound a) Show SMILES C[C@H](Nc1cc(Cl)nc2n(ncc12)[C@@H]1O[C@H](COP(O)(=O)CP(O)(O)=O)[C@@H](O)[C@H]1O)c1ccccc1F |r| Show InChI InChI=1S/C20H24ClFN4O9P2/c1-10(11-4-2-3-5-13(11)22)24-14-6-16(21)25-19-12(14)7-23-26(19)20-18(28)17(27)15(35-20)8-34-37(32,33)9-36(29,30)31/h2-7,10,15,17-18,20,27-28H,8-9H2,1H3,(H,24,25)(H,32,33)(H2,29,30,31)/t10-,15+,17+,18+,20+/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of NTPDase 8 (unknown origin) expressed in CHO cells using ATP as substrate preincubated for 1 hr followed by substrate addition and measu...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00525 BindingDB Entry DOI: 10.7270/Q29W0K29
					More data for this Ligand-Target Pair
Ectonucleoside triphosphate diphosphohydrolase 8 (Homo sapiens (Human))	BDBM50561221 (CHEMBL4745473 | US11377469, Example 95) Show SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COCP(O)(O)=O)n1ncc2c(NC3CCCC3)nc(Cl)nc12 |r| Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human NTPDase-8 expressed in CHO-K1 cells in presence of DNA/LTX mixture				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01835 BindingDB Entry DOI: 10.7270/Q2NG4VF1
					More data for this Ligand-Target Pair
Ectonucleoside triphosphate diphosphohydrolase 8 (Homo sapiens (Human))	BDBM50527649 (CHEMBL4467828) Show SMILES Clc1cc(cc2n(nnc12)-c1ccc2cn[nH]c2c1)-c1ccnn1Cc1ccc(cc1)C#N Show InChI InChI=1S/C24H15ClN8/c25-20-9-18(22-7-8-28-32(22)14-16-3-1-15(12-26)2-4-16)10-23-24(20)30-31-33(23)19-6-5-17-13-27-29-21(17)11-19/h1-11,13H,14H2,(H,27,29)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Arcus Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human NTPDase 8 expressed in CHO cells using ATP as substrate preincubated for 1 hr followed by substrate addition and measured after 5...				J Med Chem 63: 3935-3955 (2020) Article DOI: 10.1021/acs.jmedchem.9b01713 BindingDB Entry DOI: 10.7270/Q2G1648T
					More data for this Ligand-Target Pair
Ectonucleoside triphosphate diphosphohydrolase 8 (Homo sapiens (Human))	BDBM50552128 (CHEMBL4787368) Show SMILES OS(=O)(=O)C1=CC\C(=N/C(=O)C2=C\C(C=CC2)=N\C(=O)C2=CC=C\C(C2)=N/C(=O)/N=C2/CC(=CC=C2)C(=O)\N=C2\CC(=CC=C2)C(=O)\N=C2/CC=C(c3cc(cc(c23)S(O)(=O)=O)S(O)(=O)=O)S(O)(=O)=O)c2c1cc(cc2S(O)(=O)=O)S(O)(=O)=O |c:14,23,34,36,44,46,54,t:4,11,21| Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human NTPDase8 expressed in green monkey Cos-7 cells using ATP as substrate preincubated for 3 mins followed by substrate addition by m...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01044 BindingDB Entry DOI: 10.7270/Q2B27ZZ6
					More data for this Ligand-Target Pair
Ectonucleoside triphosphate diphosphohydrolase 8 (Homo sapiens (Human))	BDBM50179360 (CHEMBL3040216) Show SMILES CC1=CCC(=C\C1=N\C(=O)C1=CC=C\C(C1)=N/C(=O)/N=C1/CC(=CC=C1)C(=O)\N=C1\CC(=CC=C1C)C(=O)\N=C1/CC=C(c2cc(cc(c12)S(O)(=O)=O)S(O)(=O)=O)S(O)(=O)=O)C(=O)\N=C1/CC=C(c2cc(cc(c12)S(O)(=O)=O)S(O)(=O)=O)S(O)(=O)=O |c:4,13,24,26,34,36,45,72,t:1,11| Show InChI InChI=1S/C51H40N6O23S6/c1-25-9-11-29(49(60)54-37-13-15-41(83(69,70)71)35-21-33(81(63,64)65)23-43(45(35)37)85(75,76)77)19-39(25)56-47(58)27-5-3-7-31(17-27)52-51(62)53-32-8-4-6-28(18-32)48(59)57-40-20-30(12-10-26(40)2)50(61)55-38-14-16-42(84(72,73)74)36-22-34(82(66,67)68)24-44(46(36)38)86(78,79)80/h3-11,15-16,20-24H,12-14,17-19H2,1-2H3,(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80)/b52-31+,53-32+,54-37+,55-38+,56-39-,57-40-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Rostock Curated by ChEMBL					Assay Description Inhibition of human NTPDase8 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...				Eur J Med Chem 138: 816-829 (2017) Article DOI: 10.1016/j.ejmech.2017.07.017 BindingDB Entry DOI: 10.7270/Q20R9RXT
					More data for this Ligand-Target Pair
Ectonucleoside triphosphate diphosphohydrolase 8 (Homo sapiens (Human))	BDBM50179360 (CHEMBL3040216) Show SMILES CC1=CCC(=C\C1=N\C(=O)C1=CC=C\C(C1)=N/C(=O)/N=C1/CC(=CC=C1)C(=O)\N=C1\CC(=CC=C1C)C(=O)\N=C1/CC=C(c2cc(cc(c12)S(O)(=O)=O)S(O)(=O)=O)S(O)(=O)=O)C(=O)\N=C1/CC=C(c2cc(cc(c12)S(O)(=O)=O)S(O)(=O)=O)S(O)(=O)=O |c:4,13,24,26,34,36,45,72,t:1,11| Show InChI InChI=1S/C51H40N6O23S6/c1-25-9-11-29(49(60)54-37-13-15-41(83(69,70)71)35-21-33(81(63,64)65)23-43(45(35)37)85(75,76)77)19-39(25)56-47(58)27-5-3-7-31(17-27)52-51(62)53-32-8-4-6-28(18-32)48(59)57-40-20-30(12-10-26(40)2)50(61)55-38-14-16-42(84(72,73)74)36-22-34(82(66,67)68)24-44(46(36)38)86(78,79)80/h3-11,15-16,20-24H,12-14,17-19H2,1-2H3,(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80)/b52-31+,53-32+,54-37+,55-38+,56-39-,57-40-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human NTPDase8 expressed in green monkey Cos-7 cells using ATP as substrate preincubated for 3 mins followed by substrate addition by m...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01044 BindingDB Entry DOI: 10.7270/Q2B27ZZ6
					More data for this Ligand-Target Pair
Ectonucleoside triphosphate diphosphohydrolase 8 (Homo sapiens (Human))	BDBM50276782 (CHEMBL4165654) Show SMILES FC(F)(F)c1nc2c(cccc2c(Cl)c1Br)-c1ccsc1 Show InChI InChI=1S/C14H6BrClF3NS/c15-10-11(16)9-3-1-2-8(7-4-5-21-6-7)12(9)20-13(10)14(17,18)19/h1-6H	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Rostock Curated by ChEMBL					Assay Description Inhibition of human NTPDase8 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...				Eur J Med Chem 138: 816-829 (2017) Article DOI: 10.1016/j.ejmech.2017.07.017 BindingDB Entry DOI: 10.7270/Q20R9RXT
					More data for this Ligand-Target Pair
Ectonucleoside triphosphate diphosphohydrolase 8 (Homo sapiens (Human))	BDBM50276794 (CHEMBL4161473) Show SMILES FC(F)(F)c1nc2c(cccc2c(Cl)c1-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C22H13ClF3N/c23-19-17-13-7-12-16(14-8-3-1-4-9-14)20(17)27-21(22(24,25)26)18(19)15-10-5-2-6-11-15/h1-13H	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Rostock Curated by ChEMBL					Assay Description Inhibition of human NTPDase8 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...				Eur J Med Chem 138: 816-829 (2017) Article DOI: 10.1016/j.ejmech.2017.07.017 BindingDB Entry DOI: 10.7270/Q20R9RXT
					More data for this Ligand-Target Pair
Ectonucleoside triphosphate diphosphohydrolase 8 (Homo sapiens (Human))	BDBM50276781 (CHEMBL4159729) Show SMILES Cc1cccc(c1)-c1cccc2c(-c3cccc(C)c3)c(-c3cccc(C)c3)c(nc12)C(F)(F)F Show InChI InChI=1S/C31H24F3N/c1-19-8-4-11-22(16-19)25-14-7-15-26-27(23-12-5-9-20(2)17-23)28(24-13-6-10-21(3)18-24)30(31(32,33)34)35-29(25)26/h4-18H,1-3H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Rostock Curated by ChEMBL					Assay Description Inhibition of human NTPDase8 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...				Eur J Med Chem 138: 816-829 (2017) Article DOI: 10.1016/j.ejmech.2017.07.017 BindingDB Entry DOI: 10.7270/Q20R9RXT
					More data for this Ligand-Target Pair
Ectonucleoside triphosphate diphosphohydrolase 8 (Homo sapiens (Human))	BDBM50276785 (CHEMBL4164185) Show SMILES Fc1ccc(cc1)-c1cccc2c(-c3ccc(F)cc3)c(-c3ccc(F)cc3)c(nc12)C(F)(F)F Show InChI InChI=1S/C28H15F6N/c29-19-10-4-16(5-11-19)22-2-1-3-23-24(17-6-12-20(30)13-7-17)25(18-8-14-21(31)15-9-18)27(28(32,33)34)35-26(22)23/h1-15H	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Rostock Curated by ChEMBL					Assay Description Inhibition of human NTPDase8 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...				Eur J Med Chem 138: 816-829 (2017) Article DOI: 10.1016/j.ejmech.2017.07.017 BindingDB Entry DOI: 10.7270/Q20R9RXT
					More data for this Ligand-Target Pair
Ectonucleoside triphosphate diphosphohydrolase 8 (Homo sapiens (Human))	BDBM50276791 (CHEMBL4164891) Show SMILES FC(F)(F)c1nc2c(cccc2c(Cl)c1Br)-c1cccc(c1)C#N Show InChI InChI=1S/C17H7BrClF3N2/c18-13-14(19)12-6-2-5-11(10-4-1-3-9(7-10)8-23)15(12)24-16(13)17(20,21)22/h1-7H	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Rostock Curated by ChEMBL					Assay Description Inhibition of human NTPDase8 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...				Eur J Med Chem 138: 816-829 (2017) Article DOI: 10.1016/j.ejmech.2017.07.017 BindingDB Entry DOI: 10.7270/Q20R9RXT
					More data for this Ligand-Target Pair
Ectonucleoside triphosphate diphosphohydrolase 8 (Homo sapiens (Human))	BDBM50276784 (CHEMBL4159530) Show SMILES FC(F)(F)c1nc2c(Br)cccc2c(Cl)c1Br Show InChI InChI=1S/C10H3Br2ClF3N/c11-5-3-1-2-4-7(13)6(12)9(10(14,15)16)17-8(4)5/h1-3H	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Rostock Curated by ChEMBL					Assay Description Inhibition of human NTPDase8 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...				Eur J Med Chem 138: 816-829 (2017) Article DOI: 10.1016/j.ejmech.2017.07.017 BindingDB Entry DOI: 10.7270/Q20R9RXT
					More data for this Ligand-Target Pair
Ectonucleoside triphosphate diphosphohydrolase 8 (Homo sapiens (Human))	BDBM50276789 (CHEMBL4175913) Show SMILES FC(F)(F)c1[nH]c2c(Br)cccc2c(=O)c1Br Show InChI InChI=1S/C10H4Br2F3NO/c11-5-3-1-2-4-7(5)16-9(10(13,14)15)6(12)8(4)17/h1-3H,(H,16,17)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Rostock Curated by ChEMBL					Assay Description Inhibition of human NTPDase8 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...				Eur J Med Chem 138: 816-829 (2017) Article DOI: 10.1016/j.ejmech.2017.07.017 BindingDB Entry DOI: 10.7270/Q20R9RXT
					More data for this Ligand-Target Pair
Ectonucleoside triphosphate diphosphohydrolase 8 (Homo sapiens (Human))	BDBM50276786 (CHEMBL4172790) Show SMILES FC(F)(F)c1ccc(cc1)-c1cccc2c(Cl)c(Br)c(nc12)C(F)(F)F Show InChI InChI=1S/C17H7BrClF6N/c18-12-13(19)11-3-1-2-10(14(11)26-15(12)17(23,24)25)8-4-6-9(7-5-8)16(20,21)22/h1-7H	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Rostock Curated by ChEMBL					Assay Description Inhibition of human NTPDase8 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...				Eur J Med Chem 138: 816-829 (2017) Article DOI: 10.1016/j.ejmech.2017.07.017 BindingDB Entry DOI: 10.7270/Q20R9RXT
					More data for this Ligand-Target Pair
Ectonucleoside triphosphate diphosphohydrolase 8 (Homo sapiens (Human))	BDBM50276783 (CHEMBL4169839) Show SMILES FC(F)(F)c1nc2c(cccc2c(-c2ccccc2)c1-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C28H18F3N/c29-28(30,31)27-25(21-15-8-3-9-16-21)24(20-13-6-2-7-14-20)23-18-10-17-22(26(23)32-27)19-11-4-1-5-12-19/h1-18H	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Rostock Curated by ChEMBL					Assay Description Inhibition of human NTPDase8 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...				Eur J Med Chem 138: 816-829 (2017) Article DOI: 10.1016/j.ejmech.2017.07.017 BindingDB Entry DOI: 10.7270/Q20R9RXT
					More data for this Ligand-Target Pair
Ectonucleoside triphosphate diphosphohydrolase 8 (Homo sapiens (Human))	BDBM50276780 (CHEMBL4172933) Show SMILES COc1ccc(cc1)-c1cccc2c(Cl)c(Br)c(nc12)C(F)(F)F Show InChI InChI=1S/C17H10BrClF3NO/c1-24-10-7-5-9(6-8-10)11-3-2-4-12-14(19)13(18)16(17(20,21)22)23-15(11)12/h2-8H,1H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Rostock Curated by ChEMBL					Assay Description Inhibition of human NTPDase8 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...				Eur J Med Chem 138: 816-829 (2017) Article DOI: 10.1016/j.ejmech.2017.07.017 BindingDB Entry DOI: 10.7270/Q20R9RXT
					More data for this Ligand-Target Pair
Ectonucleoside triphosphate diphosphohydrolase 8 (Homo sapiens (Human))	BDBM50276790 (CHEMBL4174849) Show SMILES COc1ccc(cc1)-c1cccc2c(-c3ccc(OC)cc3)c(-c3ccc(OC)cc3)c(nc12)C(F)(F)F Show InChI InChI=1S/C31H24F3NO3/c1-36-22-13-7-19(8-14-22)25-5-4-6-26-27(20-9-15-23(37-2)16-10-20)28(21-11-17-24(38-3)18-12-21)30(31(32,33)34)35-29(25)26/h4-18H,1-3H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Rostock Curated by ChEMBL					Assay Description Inhibition of human NTPDase8 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...				Eur J Med Chem 138: 816-829 (2017) Article DOI: 10.1016/j.ejmech.2017.07.017 BindingDB Entry DOI: 10.7270/Q20R9RXT
					More data for this Ligand-Target Pair
Ectonucleoside triphosphate diphosphohydrolase 8 (Homo sapiens (Human))	BDBM50276787 (CHEMBL4173693) Show SMILES Cc1ccc(cc1)-c1cccc2c(-c3ccc(C)cc3)c(-c3ccc(C)cc3)c(nc12)C(F)(F)F Show InChI InChI=1S/C31H24F3N/c1-19-7-13-22(14-8-19)25-5-4-6-26-27(23-15-9-20(2)10-16-23)28(24-17-11-21(3)12-18-24)30(31(32,33)34)35-29(25)26/h4-18H,1-3H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Rostock Curated by ChEMBL					Assay Description Inhibition of human NTPDase8 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...				Eur J Med Chem 138: 816-829 (2017) Article DOI: 10.1016/j.ejmech.2017.07.017 BindingDB Entry DOI: 10.7270/Q20R9RXT
					More data for this Ligand-Target Pair
Ectonucleoside triphosphate diphosphohydrolase 8 (Homo sapiens (Human))	BDBM50276788 (CHEMBL4162261) Show SMILES COc1ccc(OC)c(c1)-c1cccc2c(Cl)c(Br)c(nc12)C(F)(F)F Show InChI InChI=1S/C18H12BrClF3NO2/c1-25-9-6-7-13(26-2)12(8-9)10-4-3-5-11-15(20)14(19)17(18(21,22)23)24-16(10)11/h3-8H,1-2H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Rostock Curated by ChEMBL					Assay Description Inhibition of human NTPDase8 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...				Eur J Med Chem 138: 816-829 (2017) Article DOI: 10.1016/j.ejmech.2017.07.017 BindingDB Entry DOI: 10.7270/Q20R9RXT
					More data for this Ligand-Target Pair