BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'trans-Sialidase (TS)'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Trans-sialidase [3-643] (Trypanosoma cruzi)	BDBM50048093 (CHEBI:610092 \| CHEMBL503075 \| Lactoside \| Methyl B...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	11
Universidade Federal do Rio de Janeiro					Assay Description Solutions of TS, TSY342H, and TSD247A in 20 mM Tris-HCl were exchanged with deuterated PBS using four cycles of concentration with Amicon Ultra (50,0...				J Biol Chem 289: 423-36 (2014) Article DOI: 10.1074/jbc.M112.399303 BindingDB Entry DOI: 10.7270/Q2VT1QZ8
Universidade Federal do Rio de Janeiro					More data for this Ligand-Target Pair
Trans-sialidase [3-643] (Trypanosoma cruzi)	BDBM217357 (NeuSGal \| methyl-S-(5-acetamide-3,5-dideoxy-D-glyc...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	4.56E+5	n/a	n/a	n/a	n/a	11
Universidade Federal do Rio de Janeiro					Assay Description Solutions of TS, TSY342H, and TSD247A in 20 mM Tris-HCl were exchanged with deuterated PBS using four cycles of concentration with Amicon Ultra (50,0...				J Biol Chem 289: 423-36 (2014) Article DOI: 10.1074/jbc.M112.399303 BindingDB Entry DOI: 10.7270/Q2VT1QZ8
Universidade Federal do Rio de Janeiro					More data for this Ligand-Target Pair