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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human)) | BDBM320461 (2-(4-{[2-(1,3-Dimethyl-1H-pyrazol-4-yl)-6-(morphol...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.54E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM320473 (US10174035, Compound 19 | [4-(Morpholin-4-yl)piper...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM320495 (US10174035, Compound 41 | [2-(1,3-Dimethyl-1H-pyra...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 3-kinase regulatory subunit alpha (Homo sapiens (Human)) | BDBM320518 (2-(1-Methyl-1H-pyrazol-4-yl)-N-{2-[1-methylpyrroli...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 984 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 3-kinase regulatory subunit beta (Homo sapiens (Human)) | BDBM320519 (US10174035, Compound 65 | {4-[cis-2,6-Dimethylmorp...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM320527 (US10174035, Compound 72 | [6-(Morpholin-4-yl)-2-(1...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human)) | BDBM320534 (US10174035, Compound 78 | [5-(1-Methyl-1H-pyrazol-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 640 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM320534 (US10174035, Compound 78 | [5-(1-Methyl-1H-pyrazol-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM320535 (US10174035, Compound 79 | [6-Fluoro-5-(1-methyl-1H...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM320538 (2-(4-{[6-Fluoro-5-(1-methyl-1H-pyrazol-4-yl)-7-(mo...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 3-kinase regulatory subunit beta (Homo sapiens (Human)) | BDBM320542 (1-{[5-(1,3-Dimethyl-1H-pyrazol-4-yl)-6-fluoro-7-(m...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 3-kinase regulatory subunit beta (Homo sapiens (Human)) | BDBM320554 (US10174035, Compound 97 | [4-(Dimethylamino)piperi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM320554 (US10174035, Compound 97 | [4-(Dimethylamino)piperi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 3-kinase regulatory subunit alpha (Homo sapiens (Human)) | BDBM320570 (US10174035, Compound 113 | {4-[cis-2,6-Dimethylmor...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM320465 (US10174035, Compound 11 | [2-(1-Methyl-1H-pyrazol-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM320467 (US10174035, Compound 13 | [2-(1-Methyl-1H-pyrazol-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 88 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM320468 (US10174035, Compound 14 | [4-(2-Hydroxypropan-2-yl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM320469 ((1,1-Dioxidothiomorpholin-4-yl)[2-(1-methyl-1H-pyr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 123 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM320470 (US10174035, Compound 16 | [2-(3,5-Dimethyl-1H-pyra...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 88 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM320480 (N-(1-{[2-(1-methyl-1H-pyrazol-4-yl)-6-(morpholin-4...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 101 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM320496 (US10174035, Compound 42 | [4-(Morpholin-4-yl)piper...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM320502 (N,N-Dimethyl-2-(1-methyl-1H-pyrazol-4-yl)-6-(morph...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 76 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM320515 (9-Methyl-2-(1-methyl-1H-pyrazol-4-yl)-6-(morpholin...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM320521 (9-Methyl-2-(1-methyl-1H-pyrazol-4-yl)-6-(morpholin...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM320558 (US10174035, Compound 101 | [4-(Dimethylamino)piper...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM320571 (US10174035, Compound 114 | {4-[cis-2,6-Dimethylmor...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 72 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM320576 (US10174035, Compound 119 | {3-[(2R,6S)-2,6-dimethy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM320578 (N-methyl-5-(1-methyl-1H-pyrazol-4-yl)-7-(morpholin...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM320587 (1-Methyl-4-(1-{[2-(1-methyl-1H-pyrazol-4-yl)-6-(mo...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human)) | BDBM320538 (2-(4-{[6-Fluoro-5-(1-methyl-1H-pyrazol-4-yl)-7-(mo...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 3-kinase regulatory subunit alpha (Homo sapiens (Human)) | BDBM320458 (US10174035, Compound 5 | {4-[cis-2,6-Dimethylmorph...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human)) | BDBM320458 (US10174035, Compound 5 | {4-[cis-2,6-Dimethylmorph...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.18E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human)) | BDBM320473 (US10174035, Compound 19 | [4-(Morpholin-4-yl)piper...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.67E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human)) | BDBM320495 (US10174035, Compound 41 | [2-(1,3-Dimethyl-1H-pyra...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 3-kinase regulatory subunit alpha (Homo sapiens (Human)) | BDBM320521 (9-Methyl-2-(1-methyl-1H-pyrazol-4-yl)-6-(morpholin...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 3-kinase regulatory subunit alpha (Homo sapiens (Human)) | BDBM320522 (2-(1-Methyl-1H-pyrazol-4-yl)-6-(morpholin-4-yl)-N-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human)) | BDBM320527 (US10174035, Compound 72 | [6-(Morpholin-4-yl)-2-(1...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 3-kinase regulatory subunit beta (Homo sapiens (Human)) | BDBM320534 (US10174035, Compound 78 | [5-(1-Methyl-1H-pyrazol-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 3-kinase regulatory subunit beta (Homo sapiens (Human)) | BDBM320535 (US10174035, Compound 79 | [6-Fluoro-5-(1-methyl-1H...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human)) | BDBM320544 (US10174035, Compound 87 | [5-(1,3-Dimethyl-1H-pyra...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 3-kinase regulatory subunit alpha (Homo sapiens (Human)) | BDBM320551 (US10174035, Compound 94 | [5-(1,3-Dimethyl-1H-pyra...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 971 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 3-kinase regulatory subunit alpha (Homo sapiens (Human)) | BDBM320554 (US10174035, Compound 97 | [4-(Dimethylamino)piperi...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM320455 (2-(1-Methyl-1H-pyrazol-4-yl)-6-(morpholin-4-yl)-N-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM320487 (N-cyclohexyl-2-(1-methyl-1H-pyrazol-4-yl)-6-(morph...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 366 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM320492 (N-[(3R)-1-{[2-(1-methyl-1H-pyrazol-4-yl)-6-(morpho...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM320493 (1-(4-{[2-(1-Methyl-1H-pyrazol-4-yl)-6-(morpholin-4...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM320513 (N-ethyl-2-(1-methyl-1H-pyrazol-4-yl)-6-(morpholin-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 206 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM320516 (US10174035, Compound 62 | [(3S)-3-Hydroxypyrrolidi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 61 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM320525 (N-[2-(4-methylpiperazin-1-yl)ethyl]-2-(1-methyl-1H...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM320539 (US10174035, Compound 83 | [3-(Cyclopropylmethyl)-5...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 92 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited US Patent | Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo... | US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
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