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Patent code US8486989

Compile Data Set for Download or QSAR
Found 1 hit of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Genome polyprotein [1027-1711]


(Hepatitis C virus (HCV))		BDBM98165
PNG
(US8486989, IA)
Show SMILES CCC[C@H](NC(=O)[C@@H]1[C@H]2[C@@H]3C[C@@H](C=C3)[C@H]2CN1C(=O)[C@@H](NC(=O)[C@@H](NC(=O)c1cnccn1)C1CCCCC1)C(C)(C)C)C(=O)C(=O)NC1CC1 |r,c:12|
Show InChI InChI=1S/C38H53N7O6/c1-5-9-26(31(46)36(50)41-24-14-15-24)42-35(49)30-28-23-13-12-22(18-23)25(28)20-45(30)37(51)32(38(2,3)4)44-34(48)29(21-10-7-6-8-11-21)43-33(47)27-19-39-16-17-40-27/h12-13,16-17,19,21-26,28-30,32H,5-11,14-15,18,20H2,1-4H3,(H,41,50)(H,42,49)(H,43,47)(H,44,48)/t22-,23+,25-,26+,28+,29+,30+,32-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
 39n/a 202n/an/an/an/a7.8n/a



Vertex Pharmaceuticals Incorporated

US Patent


Assay Description
Inhibition activity of HCV NS3-NS4A.

US Patent US8486989 (2013)


BindingDB Entry DOI: 10.7270/Q2FB51K1
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%