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Patent code US9150546

Compile Data Set for Download or QSAR

Found 325 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183079
PNG
(US9150546, I-126 | US9688643, I-126 | US9718790, I...)
Show SMILES CC(C)n1c(=O)nc(Nc2cccc(c2)C(F)(F)F)n(Cc2ccc(F)cc2)c1=O
Show InChI InChI=1S/C20H18F4N4O2/c1-12(2)28-18(29)26-17(25-16-5-3-4-14(10-16)20(22,23)24)27(19(28)30)11-13-6-8-15(21)9-7-13/h3-10,12H,11H2,1-2H3,(H,25,26,29)
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US Patent
n/an/a 689n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183085
PNG
(US9150546, I-162 | US9688643, I-162 | US9718790, I...)
Show SMILES CC(C)n1c(=O)nc(Nc2cccc(c2)C(F)(F)F)n(Cc2ccc(Cl)cn2)c1=O
Show InChI InChI=1S/C19H17ClF3N5O2/c1-11(2)28-17(29)26-16(25-14-5-3-4-12(8-14)19(21,22)23)27(18(28)30)10-15-7-6-13(20)9-24-15/h3-9,11H,10H2,1-2H3,(H,25,26,29)
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US Patent
n/an/a 379n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183093
PNG
(US9150546, I-218 | US9688643, I-218 | US9718790, I...)
Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(C)c(c2)[N+]([O-])=O)cc1
Show InChI InChI=1S/C23H27N5O5/c1-14(2)27-22(29)25-21(24-18-8-10-19(11-9-18)33-15(3)4)26(23(27)30)13-17-7-6-16(5)20(12-17)28(31)32/h6-12,14-15H,13H2,1-5H3,(H,24,25,29)
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n/an/a 505n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183103
PNG
(US9150546, I-240 | US9688643, I-240)
Show SMILES CC(C)n1c(=O)nc(Nc2ccc(Oc3ccccc3)c(Cl)c2)n(Cc2ccc(Cl)cc2)c1=O
Show InChI InChI=1S/C25H22Cl2N4O3/c1-16(2)31-24(32)29-23(30(25(31)33)15-17-8-10-18(26)11-9-17)28-19-12-13-22(21(27)14-19)34-20-6-4-3-5-7-20/h3-14,16H,15H2,1-2H3,(H,28,29,32)
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n/an/a 953n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183105
PNG
(US9150546, I-242 | US9688643, I-242 | US9718790, I...)
Show SMILES CC(C)n1c(=O)nc(Nc2ccc(OC3CCNCC3)c(Cl)c2)n(Cc2ccc(Cl)cc2)c1=O
Show InChI InChI=1S/C24H27Cl2N5O3/c1-15(2)31-23(32)29-22(30(24(31)33)14-16-3-5-17(25)6-4-16)28-18-7-8-21(20(26)13-18)34-19-9-11-27-12-10-19/h3-8,13,15,19,27H,9-12,14H2,1-2H3,(H,28,29,32)
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n/an/a 787n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183109
PNG
(US9150546, I-246 | US9688643, I-246 | US9718790, I...)
Show SMILES CC(C)n1c(=O)nc(Nc2ccc3[nH]c(=O)oc3c2)n(Cc2ccc(Cl)cc2)c1=O
Show InChI InChI=1S/C20H18ClN5O4/c1-11(2)26-18(27)24-17(22-14-7-8-15-16(9-14)30-19(28)23-15)25(20(26)29)10-12-3-5-13(21)6-4-12/h3-9,11H,10H2,1-2H3,(H,23,28)(H,22,24,27)
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US Patent
n/an/a 996n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183113
PNG
(US9150546, I-256 | US9688643, I-256 | US9718790, I...)
Show SMILES CC(C)CNC(=O)c1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C24H28ClN5O3/c1-15(2)13-26-21(31)18-7-11-20(12-8-18)27-22-28-23(32)30(16(3)4)24(33)29(22)14-17-5-9-19(25)10-6-17/h5-12,15-16H,13-14H2,1-4H3,(H,26,31)(H,27,28,32)
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n/an/a 867n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183117
PNG
(US9150546, I-269 | US9688643, I-269 | US9718790, I...)
Show SMILES CC(C)Oc1ccc(Nc2nc(=O)[nH]c(=O)n2Cc2ccc(Cl)cc2)cc1F
Show InChI InChI=1S/C19H18ClFN4O3/c1-11(2)28-16-8-7-14(9-15(16)21)22-17-23-18(26)24-19(27)25(17)10-12-3-5-13(20)6-4-12/h3-9,11H,10H2,1-2H3,(H2,22,23,24,26,27)
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n/an/a 415n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183131
PNG
(US9150546, I-284 | US9688643, I-284 | US9718790, I...)
Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(CC(O)=O)c(=O)n2Cc2ccc(Cl)cc2)cc1F
Show InChI InChI=1S/C21H20ClFN4O5/c1-12(2)32-17-8-7-15(9-16(17)23)24-19-25-20(30)27(11-18(28)29)21(31)26(19)10-13-3-5-14(22)6-4-13/h3-9,12H,10-11H2,1-2H3,(H,28,29)(H,24,25,30)
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US Patent
n/an/a 629n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183134
PNG
(US9150546, I-287 | US9688643, I-287 | US9718790, I...)
Show SMILES Clc1ccc(Cn2c(Nc3ccc(cc3)-c3ccon3)nc(=O)n(CCN3CCOCC3)c2=O)cc1
Show InChI InChI=1S/C25H25ClN6O4/c26-20-5-1-18(2-6-20)17-32-23(27-21-7-3-19(4-8-21)22-9-14-36-29-22)28-24(33)31(25(32)34)11-10-30-12-15-35-16-13-30/h1-9,14H,10-13,15-17H2,(H,27,28,33)
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US Patent
n/an/a 222n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183138
PNG
(US9150546, I-291 | US9688643, I-291 | US9718790, I...)
Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(CCC#N)c(=O)n2Cc2ccc(Cl)cc2)cc1F
Show InChI InChI=1S/C22H21ClFN5O3/c1-14(2)32-19-9-8-17(12-18(19)24)26-20-27-21(30)28(11-3-10-25)22(31)29(20)13-15-4-6-16(23)7-5-15/h4-9,12,14H,3,11,13H2,1-2H3,(H,26,27,30)
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n/an/a 9n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183163
PNG
(US9150546, I-323 | US9688643, I-323 | US9718790, I...)
Show SMILES CC(C)COc1ccc(Nc2nc(=O)n(CCO)c(=O)n2Cc2ccc(Cl)cc2)cc1F
Show InChI InChI=1S/C22H24ClFN4O4/c1-14(2)13-32-19-8-7-17(11-18(19)24)25-20-26-21(30)27(9-10-29)22(31)28(20)12-15-3-5-16(23)6-4-15/h3-8,11,14,29H,9-10,12-13H2,1-2H3,(H,25,26,30)
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n/an/a 148n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183191
PNG
(US9150546, I-355 | US9688643, I-355 | US9718790, I...)
Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(CCC(O)=O)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl
Show InChI InChI=1S/C22H22Cl2N4O5/c1-13(2)33-18-8-7-16(11-17(18)24)25-20-26-21(31)27(10-9-19(29)30)22(32)28(20)12-14-3-5-15(23)6-4-14/h3-8,11,13H,9-10,12H2,1-2H3,(H,29,30)(H,25,26,31)
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n/an/a 20n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183194
PNG
(US9150546, I-358 | US9688643, I-358 | US9718790, I...)
Show SMILES CC(C)Cc1ccc(Nc2nc(=O)n(CCCO)c(=O)n2Cc2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C23H27ClN4O3/c1-16(2)14-17-6-10-20(11-7-17)25-21-26-22(30)27(12-3-13-29)23(31)28(21)15-18-4-8-19(24)9-5-18/h4-11,16,29H,3,12-15H2,1-2H3,(H,25,26,30)
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n/an/a 55n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183198
PNG
(US9150546, I-362 | US9688643, I-362 | US9718790, I...)
Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(CCCO)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl
Show InChI InChI=1S/C22H24Cl2N4O4/c1-14(2)32-19-9-8-17(12-18(19)24)25-20-26-21(30)27(10-3-11-29)22(31)28(20)13-15-4-6-16(23)7-5-15/h4-9,12,14,29H,3,10-11,13H2,1-2H3,(H,25,26,30)
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n/an/a 7n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183221
PNG
(US9150546, I-388 | US9688643, I-388 | US9718790, I...)
Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(CCNC(=O)N(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1F
Show InChI InChI=1S/C24H28ClFN6O4/c1-15(2)36-20-10-9-18(13-19(20)26)28-21-29-23(34)31(12-11-27-22(33)30(3)4)24(35)32(21)14-16-5-7-17(25)8-6-16/h5-10,13,15H,11-12,14H2,1-4H3,(H,27,33)(H,28,29,34)
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n/an/a 36n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183230
PNG
(US9150546, I-400 | US9688643, I-400 | US9718790, I...)
Show SMILES CC(C)Oc1ccc(cc1F)\N=c1/[nH]c(=O)n(CC(=O)NCC(O)=O)c(=O)n1Cc1ccc(Cl)cc1
Show InChI InChI=1S/C23H23ClFN5O6/c1-13(2)36-18-8-7-16(9-17(18)25)27-21-28-22(34)30(12-19(31)26-10-20(32)33)23(35)29(21)11-14-3-5-15(24)6-4-14/h3-9,13H,10-12H2,1-2H3,(H,26,31)(H,32,33)(H,27,28,34)
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n/an/a 44n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183237
PNG
(US9150546, I-407 | US9688643, I-407 | US9718790, I...)
Show SMILES CC(C)Oc1ccc(cc1Cl)\N=c1/[nH]c(=O)n(CCC(C)(C)C(=O)OCc2ccccc2)c(=O)n1Cc1ccc(Cl)cc1
Show InChI InChI=1S/C32H34Cl2N4O5/c1-21(2)43-27-15-14-25(18-26(27)34)35-29-36-30(40)37(31(41)38(29)19-22-10-12-24(33)13-11-22)17-16-32(3,4)28(39)42-20-23-8-6-5-7-9-23/h5-15,18,21H,16-17,19-20H2,1-4H3,(H,35,36,40)
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US Patent
n/an/a 27n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183261
PNG
(US9150546, II-002 | US9688643, II-002 | US9718790,...)
Show SMILES CC(C)Oc1ccc(Nc2nc(OCCO)nc(=O)n2Cc2ccc(Cl)cc2)cc1F
Show InChI InChI=1S/C21H22ClFN4O4/c1-13(2)31-18-8-7-16(11-17(18)23)24-19-25-20(30-10-9-28)26-21(29)27(19)12-14-3-5-15(22)6-4-14/h3-8,11,13,28H,9-10,12H2,1-2H3,(H,24,25,26,29)
PDB

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n/an/a 79n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183272
PNG
(US9150546, I-440 | US9688643, I-440 | US9718790, I...)
Show SMILES CC(C)Oc1ccc(cc1F)\N=c1/[nH]c(=O)n(CCC(=O)NCC(N)=O)c(=O)n1Cc1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClFN6O5/c1-14(2)37-19-8-7-17(11-18(19)26)29-22-30-23(35)31(10-9-21(34)28-12-20(27)33)24(36)32(22)13-15-3-5-16(25)6-4-15/h3-8,11,14H,9-10,12-13H2,1-2H3,(H2,27,33)(H,28,34)(H,29,30,35)
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n/an/a 55n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183273
PNG
(US9150546, I-441 | US9688643, I-441 | US9718790, I...)
Show SMILES CCOc1ccc(cc1Cl)\N=c1/[nH]c(=O)n(CC(C)(C)C(=O)OC)c(=O)n1Cc1ccc(Cl)cc1
Show InChI InChI=1S/C24H26Cl2N4O5/c1-5-35-19-11-10-17(12-18(19)26)27-21-28-22(32)30(14-24(2,3)20(31)34-4)23(33)29(21)13-15-6-8-16(25)9-7-15/h6-12H,5,13-14H2,1-4H3,(H,27,28,32)
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n/an/a 11n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183282
PNG
(US9150546, I-451 | US9688643, I-451 | US9718790, I...)
Show SMILES CC(C)Oc1ccc(cc1F)\N=c1/[nH]c(=O)n(Cc2cccc(c2)C(O)=O)c(=O)n1Cc1ccc(Cl)cc1
Show InChI InChI=1S/C27H24ClFN4O5/c1-16(2)38-23-11-10-21(13-22(23)29)30-25-31-26(36)33(15-18-4-3-5-19(12-18)24(34)35)27(37)32(25)14-17-6-8-20(28)9-7-17/h3-13,16H,14-15H2,1-2H3,(H,34,35)(H,30,31,36)
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n/an/a 16n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183284
PNG
(US9150546, I-453 | US9688643, I-453 | US9718790, I...)
Show SMILES COC(=O)[C@@H](C)Cn1c(=O)[nH]\c(=N/c2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O |r|
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n/an/a 5n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183286
PNG
(US9150546, I-455 | US9688643, I-455 | US9718790, I...)
Show SMILES CC(C)Oc1ccc(cc1F)\N=c1/[nH]c(=O)n(C[C@@H](C)C(O)=O)c(=O)n1Cc1ccc(Cl)cc1 |r|
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n/an/a 30n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183295
PNG
(US9150546, I-464 | US9688643, I-464 | US9718790, I...)
Show SMILES Cc1ccc(cc1C)\N=c1/[nH]c(=O)n(CC(C)(C)C(O)=O)c(=O)n1Cc1ccc(Cl)cc1
Show InChI InChI=1S/C23H25ClN4O4/c1-14-5-10-18(11-15(14)2)25-20-26-21(31)28(13-23(3,4)19(29)30)22(32)27(20)12-16-6-8-17(24)9-7-16/h5-11H,12-13H2,1-4H3,(H,29,30)(H,25,26,31)
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n/an/a 564n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183300
PNG
(US9150546, I-469 | US9688643, I-469 | US9718790, I...)
Show SMILES CC(C)(Cn1c(=O)[nH]\c(=N/c2cccc(OC(F)(F)F)c2)n(Cc2ccc(Cl)cc2)c1=O)C(O)=O
Show InChI InChI=1S/C22H20ClF3N4O5/c1-21(2,17(31)32)12-30-19(33)28-18(27-15-4-3-5-16(10-15)35-22(24,25)26)29(20(30)34)11-13-6-8-14(23)9-7-13/h3-10H,11-12H2,1-2H3,(H,31,32)(H,27,28,33)
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n/an/a 101n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183314
PNG
(US9150546, I-484 | US9688643, I-484 | US9718790, I...)
Show SMILES CCOc1ccc(cc1)\N=c1/[nH]c(=O)n(C[C@@H](C)C(O)=O)c(=O)n1Cc1ccc(Cl)cc1 |r|
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n/an/a 290n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183324
PNG
(US9150546, I-494 | US9688643, I-494 | US9718790, I...)
Show SMILES COC(=O)C(C)(C)Cn1c(=O)[nH]\c(=N/c2ccc3nc(C)oc3c2)n(Cc2ccc(Cl)cc2)c1=O
Show InChI InChI=1S/C24H24ClN5O5/c1-14-26-18-10-9-17(11-19(18)35-14)27-21-28-22(32)30(13-24(2,3)20(31)34-4)23(33)29(21)12-15-5-7-16(25)8-6-15/h5-11H,12-13H2,1-4H3,(H,27,28,32)
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n/an/a 34n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183329
PNG
(US9150546, I-499 | US9688643, I-499 | US9718790, I...)
Show SMILES CC(C)Oc1ccc(cc1C)\N=c1/[nH]c(=O)[nH]c(=O)n1Cc1ccc(Cl)cc1
Show InChI InChI=1S/C20H21ClN4O3/c1-12(2)28-17-9-8-16(10-13(17)3)22-18-23-19(26)24-20(27)25(18)11-14-4-6-15(21)7-5-14/h4-10,12H,11H2,1-3H3,(H2,22,23,24,26,27)
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n/an/a 137n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183335
PNG
(US9150546, I-505 | US9688643, I-505 | US9718790, I...)
Show SMILES Cc1cc2cc(ccc2o1)\N=c1/[nH]c(=O)n(CCCC(O)=O)c(=O)n1Cc1ccc(Cl)cc1
Show InChI InChI=1S/C23H21ClN4O5/c1-14-11-16-12-18(8-9-19(16)33-14)25-21-26-22(31)27(10-2-3-20(29)30)23(32)28(21)13-15-4-6-17(24)7-5-15/h4-9,11-12H,2-3,10,13H2,1H3,(H,29,30)(H,25,26,31)
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n/an/a 120n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183366
PNG
(US9150546, I-540 | US9688643, I-540 | US9718790, I...)
Show SMILES C[C@@H](Cn1c(=O)[nH]\c(=N/c2ccc3oc(C)cc3c2)n(Cc2ccc(Cl)cc2)c1=O)C(O)=O |r|
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n/an/a 27n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183368
PNG
(US9150546, I-542 | US9688643, I-542 | US9718790, I...)
Show SMILES CCOc1ccc(cc1)\N=c1/[nH]c(=O)n(CC(C)(C)C(O)=O)c(=O)n1Cc1ccc(Cl)cc1
Show InChI InChI=1S/C23H25ClN4O5/c1-4-33-18-11-9-17(10-12-18)25-20-26-21(31)28(14-23(2,3)19(29)30)22(32)27(20)13-15-5-7-16(24)8-6-15/h5-12H,4,13-14H2,1-3H3,(H,29,30)(H,25,26,31)
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n/an/a 96n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183380
PNG
(US9150546, I-554 | US9688643, I-554 | US9718790, I...)
Show SMILES CC(C)Oc1ccc(cc1Cl)\N=c1/[nH]c(=O)n(CC(C)(C)C(O)=O)c(=O)n1CC1CCCC1
Show InChI InChI=1S/C23H31ClN4O5/c1-14(2)33-18-10-9-16(11-17(18)24)25-20-26-21(31)28(13-23(3,4)19(29)30)22(32)27(20)12-15-7-5-6-8-15/h9-11,14-15H,5-8,12-13H2,1-4H3,(H,29,30)(H,25,26,31)
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n/an/a 139n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183384
PNG
(US9150546, I-558 | US9688643, I-558 | US9718790, I...)
Show SMILES COC(=O)[C@H](C)Cn1c(=O)[nH]\c(=N/c2ccc3oc(C)cc3c2)n(Cc2ccc(Cl)cc2)c1=O |r|
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n/an/a 5n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183385
PNG
(US9150546, I-559 | US9688643, I-559 | US9718790, I...)
Show SMILES CC(C)Oc1ccc(cc1C)\N=c1/[nH]c(=O)n(C[C@H](C)C(O)=O)c(=O)n1CC1CCCCC1 |r|
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n/an/a 97n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183387
PNG
(US9150546, I-561 | US9688643, I-561 | US9718790, I...)
Show SMILES CC(C)Oc1ccc(cc1Cl)\N=c1/[nH]c(=O)n([C@H](C)CC(O)=O)c(=O)n1Cc1ccc(Cl)cc1 |r|
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n/an/a 8n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183391
PNG
(US9150546, II-012 | US9688643, II-012 | US9718790,...)
Show SMILES CC(C)Oc1ccc(cc1Cl)\N=c1/[nH]c(nc(=O)n1Cc1ccc(Cl)cc1)N1CCCC1=O
Show InChI InChI=1S/C23H23Cl2N5O3/c1-14(2)33-19-10-9-17(12-18(19)25)26-21-27-22(29-11-3-4-20(29)31)28-23(32)30(21)13-15-5-7-16(24)8-6-15/h5-10,12,14H,3-4,11,13H2,1-2H3,(H,26,27,28,32)
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n/an/a 568n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183392
PNG
(US9150546, II-013 | US9688643, II-013 | US9718790,...)
Show SMILES CCN(CC)c1nc(=O)n(Cc2ccc(Cl)cc2)\c(=N\c2ccc(OC(C)C)c(Cl)c2)[nH]1
Show InChI InChI=1S/C23H27Cl2N5O2/c1-5-29(6-2)21-27-22(26-18-11-12-20(19(25)13-18)32-15(3)4)30(23(31)28-21)14-16-7-9-17(24)10-8-16/h7-13,15H,5-6,14H2,1-4H3,(H,26,27,28,31)
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n/an/a 430n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183072
PNG
(US9150546, I-029 | US9688643, I-029 | US9718790, I...)
Show SMILES CCCCn1c(=O)nc(Nc2cccc(c2)C(F)(F)F)n(Cc2ccc(C)cc2)c1=O
Show InChI InChI=1S/C22H23F3N4O2/c1-3-4-12-28-20(30)27-19(26-18-7-5-6-17(13-18)22(23,24)25)29(21(28)31)14-16-10-8-15(2)9-11-16/h5-11,13H,3-4,12,14H2,1-2H3,(H,26,27,30)
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n/an/a 595n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183075
PNG
(US9150546, I-117 | US9688643, I-117 | US9718790, I...)
Show SMILES CC(C)n1c(=O)nc(Nc2cccc(Cl)c2)n(Cc2ccc(C)cc2)c1=O
Show InChI InChI=1S/C20H21ClN4O2/c1-13(2)25-19(26)23-18(22-17-6-4-5-16(21)11-17)24(20(25)27)12-15-9-7-14(3)8-10-15/h4-11,13H,12H2,1-3H3,(H,22,23,26)
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n/an/a 387n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183083
PNG
(US9150546, I-138 | US9688643, I-138 | US9718790, I...)
Show SMILES CCn1c(=O)nc(Nc2cccc(c2)C(F)(F)F)n(Cc2ccc(F)cc2)c1=O
Show InChI InChI=1S/C19H16F4N4O2/c1-2-26-17(28)25-16(24-15-5-3-4-13(10-15)19(21,22)23)27(18(26)29)11-12-6-8-14(20)9-7-12/h3-10H,2,11H2,1H3,(H,24,25,28)
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n/an/a 619n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183094
PNG
(US9150546, I-221 | US9688643, I-221 | US9718790, I...)
Show SMILES COC(=O)c1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(F)cc2)cc1
Show InChI InChI=1S/C21H21FN4O4/c1-13(2)26-20(28)24-19(23-17-10-6-15(7-11-17)18(27)30-3)25(21(26)29)12-14-4-8-16(22)9-5-14/h4-11,13H,12H2,1-3H3,(H,23,24,28)
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n/an/a 276n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183106
PNG
(US9150546, I-243 | US9688643, I-243 | US9718790, I...)
Show SMILES COc1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl
Show InChI InChI=1S/C20H20Cl2N4O3/c1-12(2)26-19(27)24-18(23-15-8-9-17(29-3)16(22)10-15)25(20(26)28)11-13-4-6-14(21)7-5-13/h4-10,12H,11H2,1-3H3,(H,23,24,27)
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n/an/a 450n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183112
PNG
(US9150546, I-255 | US9688643, I-255 | US9718790, I...)
Show SMILES CC(C)NC(=O)c1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C23H26ClN5O3/c1-14(2)25-20(30)17-7-11-19(12-8-17)26-21-27-22(31)29(15(3)4)23(32)28(21)13-16-5-9-18(24)10-6-16/h5-12,14-15H,13H2,1-4H3,(H,25,30)(H,26,27,31)
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n/an/a 520n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183144
PNG
(US9150546, I-297 | US9688643, I-297 | US9718790, I...)
Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(CCC(=O)N(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1F
Show InChI InChI=1S/C24H27ClFN5O4/c1-15(2)35-20-10-9-18(13-19(20)26)27-22-28-23(33)30(12-11-21(32)29(3)4)24(34)31(22)14-16-5-7-17(25)8-6-16/h5-10,13,15H,11-12,14H2,1-4H3,(H,27,28,33)
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n/an/a 45n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183147
PNG
(US9150546, I-300 | US9688643, I-300 | US9718790, I...)
Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(Cc3ccccn3)c(=O)n2Cc2ccc(Cl)cc2)cc1F
Show InChI InChI=1S/C25H23ClFN5O3/c1-16(2)35-22-11-10-19(13-21(22)27)29-23-30-24(33)32(15-20-5-3-4-12-28-20)25(34)31(23)14-17-6-8-18(26)9-7-17/h3-13,16H,14-15H2,1-2H3,(H,29,30,33)
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n/an/a 25n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183150
PNG
(US9150546, I-307 | US9688643, I-307 | US9718790, I...)
Show SMILES CCOc1ccc(Nc2nc(=O)n(CCO)c(=O)n2Cc2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C20H21ClN4O4/c1-2-29-17-9-7-16(8-10-17)22-18-23-19(27)24(11-12-26)20(28)25(18)13-14-3-5-15(21)6-4-14/h3-10,26H,2,11-13H2,1H3,(H,22,23,27)
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n/an/a 250n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183151
PNG
(US9150546, I-309 | US9688643, I-309 | US9718790, I...)
Show SMILES OCCn1c(=O)nc(Nc2cccc(OC(F)(F)F)c2)n(Cc2ccc(Cl)cc2)c1=O
Show InChI InChI=1S/C19H16ClF3N4O4/c20-13-6-4-12(5-7-13)11-27-16(25-17(29)26(8-9-28)18(27)30)24-14-2-1-3-15(10-14)31-19(21,22)23/h1-7,10,28H,8-9,11H2,(H,24,25,29)
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n/an/a 357n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183165
PNG
(US9150546, I-325 | US9688643, I-325 | US9718790, I...)
Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(CCO)c(=O)[nH]2)cc1F
Show InChI InChI=1S/C14H17FN4O4/c1-8(2)23-11-4-3-9(7-10(11)15)16-12-17-13(21)19(5-6-20)14(22)18-12/h3-4,7-8,20H,5-6H2,1-2H3,(H2,16,17,18,21,22)
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n/an/a 665n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183183
PNG
(US9150546, I-347 | US9688643, I-347 | US9718790, I...)
Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(CCO)c(=O)n2Cc2ccc(cc2)[N+]([O-])=O)cc1F
Show InChI InChI=1S/C21H22FN5O6/c1-13(2)33-18-8-5-15(11-17(18)22)23-19-24-20(29)25(9-10-28)21(30)26(19)12-14-3-6-16(7-4-14)27(31)32/h3-8,11,13,28H,9-10,12H2,1-2H3,(H,23,24,29)
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n/an/a 251n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
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* indicates data uncertainty>20%