Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Thyrotropin receptor (Homo sapiens (Human)) | BDBM60849 (US9174940, 12) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ... | US Patent US9174940 (2015) BindingDB Entry DOI: 10.7270/Q2F18XJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyrotropin receptor (Homo sapiens (Human)) | BDBM60869 (US9174940, 38) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ... | US Patent US9174940 (2015) BindingDB Entry DOI: 10.7270/Q2F18XJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyrotropin receptor (Homo sapiens (Human)) | BDBM60853 (US9174940, 27) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ... | US Patent US9174940 (2015) BindingDB Entry DOI: 10.7270/Q2F18XJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyrotropin receptor (Homo sapiens (Human)) | BDBM60855 (US9174940, 28) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ... | US Patent US9174940 (2015) BindingDB Entry DOI: 10.7270/Q2F18XJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyrotropin receptor (Homo sapiens (Human)) | BDBM60863 (US9174940, 33) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ... | US Patent US9174940 (2015) BindingDB Entry DOI: 10.7270/Q2F18XJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyrotropin receptor (Homo sapiens (Human)) | BDBM60872 (US9174940, 40) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ... | US Patent US9174940 (2015) BindingDB Entry DOI: 10.7270/Q2F18XJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyrotropin receptor (Homo sapiens (Human)) | BDBM60851 (US9174940, 18) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ... | US Patent US9174940 (2015) BindingDB Entry DOI: 10.7270/Q2F18XJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyrotropin receptor (Homo sapiens (Human)) | BDBM60867 (US9174940, 37) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ... | US Patent US9174940 (2015) BindingDB Entry DOI: 10.7270/Q2F18XJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyrotropin receptor (Homo sapiens (Human)) | BDBM60870 (US9174940, 39) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ... | US Patent US9174940 (2015) BindingDB Entry DOI: 10.7270/Q2F18XJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyrotropin receptor (Homo sapiens (Human)) | BDBM189327 (Hexanoic acid (Compound A) | US9174940, Compound A) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 88 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ... | US Patent US9174940 (2015) BindingDB Entry DOI: 10.7270/Q2F18XJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyrotropin receptor (Homo sapiens (Human)) | BDBM60860 (US9174940, 31) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ... | US Patent US9174940 (2015) BindingDB Entry DOI: 10.7270/Q2F18XJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyrotropin subunit beta (Bos taurus (Bovine)) | BDBM60862 (BDBM189328 | US9174940, 32) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ... | US Patent US9174940 (2015) BindingDB Entry DOI: 10.7270/Q2F18XJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyrotropin receptor (Homo sapiens (Human)) | BDBM60845 (US9174940, 6) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ... | US Patent US9174940 (2015) BindingDB Entry DOI: 10.7270/Q2F18XJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyrotropin receptor (Homo sapiens (Human)) | BDBM60862 (BDBM189328 | US9174940, 32) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ... | US Patent US9174940 (2015) BindingDB Entry DOI: 10.7270/Q2F18XJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyrotropin receptor (Homo sapiens (Human)) | BDBM60843 (US9174940, 1) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ... | US Patent US9174940 (2015) BindingDB Entry DOI: 10.7270/Q2F18XJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyrotropin receptor (Homo sapiens (Human)) | BDBM60848 (US9174940, 11 | US9174940, 26) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ... | US Patent US9174940 (2015) BindingDB Entry DOI: 10.7270/Q2F18XJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyrotropin receptor (Homo sapiens (Human)) | BDBM60850 (US9174940, 13) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ... | US Patent US9174940 (2015) BindingDB Entry DOI: 10.7270/Q2F18XJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyrotropin receptor (Homo sapiens (Human)) | BDBM60866 (US9174940, 36) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ... | US Patent US9174940 (2015) BindingDB Entry DOI: 10.7270/Q2F18XJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyrotropin receptor (Homo sapiens (Human)) | BDBM60862 (BDBM189328 | US9174940, 32) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ... | US Patent US9174940 (2015) BindingDB Entry DOI: 10.7270/Q2F18XJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyrotropin receptor (Homo sapiens (Human)) | BDBM60844 (US9174940, 4) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ... | US Patent US9174940 (2015) BindingDB Entry DOI: 10.7270/Q2F18XJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyrotropin receptor (Homo sapiens (Human)) | BDBM60847 (US9174940, 7) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ... | US Patent US9174940 (2015) BindingDB Entry DOI: 10.7270/Q2F18XJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyrotropin receptor (Homo sapiens (Human)) | BDBM60848 (US9174940, 11 | US9174940, 26) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ... | US Patent US9174940 (2015) BindingDB Entry DOI: 10.7270/Q2F18XJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyrotropin subunit beta (Bos taurus (Bovine)) | BDBM189329 ((+)-(1-Acetyl-4-methyl-4-phenyl-1,2,3,4-tetrahydro...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 192 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ... | US Patent US9174940 (2015) BindingDB Entry DOI: 10.7270/Q2F18XJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyrotropin receptor (Homo sapiens (Human)) | BDBM189329 ((+)-(1-Acetyl-4-methyl-4-phenyl-1,2,3,4-tetrahydro...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ... | US Patent US9174940 (2015) BindingDB Entry DOI: 10.7270/Q2F18XJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyrotropin receptor (Homo sapiens (Human)) | BDBM60856 (US9174940, 29) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ... | US Patent US9174940 (2015) BindingDB Entry DOI: 10.7270/Q2F18XJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyrotropin receptor (Homo sapiens (Human)) | BDBM60857 (US9174940, 30) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ... | US Patent US9174940 (2015) BindingDB Entry DOI: 10.7270/Q2F18XJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyrotropin receptor (Homo sapiens (Human)) | BDBM60864 (US9174940, 34) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ... | US Patent US9174940 (2015) BindingDB Entry DOI: 10.7270/Q2F18XJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyrotropin receptor (Homo sapiens (Human)) | BDBM60865 (US9174940, 35) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ... | US Patent US9174940 (2015) BindingDB Entry DOI: 10.7270/Q2F18XJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyrotropin subunit beta (Bos taurus (Bovine)) | BDBM189327 (Hexanoic acid (Compound A) | US9174940, Compound A) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 368 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ... | US Patent US9174940 (2015) BindingDB Entry DOI: 10.7270/Q2F18XJC | |||||||||||
More data for this Ligand-Target Pair |