Identical Ligands in BindingDB

Found 5 hits Enzyme Inhibition Constant Data   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
L-lactate dehydrogenase B chain   (333/333 = 100%)† (Homo sapiens (Human))	BDBM23222 (Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Ac...) Show SMILES NC(=O)C(O)=O Show InChI InChI=1S/C2H3NO3/c3-1(4)2(5)6/h(H2,3,4)(H,5,6)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents	DrugBank PDB Article PubMed	9.44E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute-CRO Curated by ChEMBL					Assay Description Competitive inhibition of human LDH1 in presence of NADH				J Med Chem 59: 487-96 (2016) Article DOI: 10.1021/acs.jmedchem.5b00168 BindingDB Entry DOI: 10.7270/Q2B27X41
					More data for this Ligand-Target Pair				3D Structure (crystal)
L-lactate dehydrogenase B chain   (333/333 = 100%)† (Homo sapiens (Human))	BDBM23222 (Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Ac...) Show SMILES NC(=O)C(O)=O Show InChI InChI=1S/C2H3NO3/c3-1(4)2(5)6/h(H2,3,4)(H,5,6)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents	DrugBank PDB Article PubMed	n/a	n/a	3.38E+4	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of human recombinant carboxy-terminal His-tagged LDHB by UV endpoint assay				Bioorg Med Chem Lett 24: 3764-71 (2014) Article DOI: 10.1016/j.bmcl.2014.06.076 BindingDB Entry DOI: 10.7270/Q2445P46
					More data for this Ligand-Target Pair				3D Structure (crystal)
L-lactate dehydrogenase B chain   (333/333 = 100%)† (Homo sapiens (Human))	BDBM23222 (Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Ac...) Show SMILES NC(=O)C(O)=O Show InChI InChI=1S/C2H3NO3/c3-1(4)2(5)6/h(H2,3,4)(H,5,6)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents	DrugBank PDB Article PubMed	n/a	n/a	3.38E+4	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of human recombinant carboxy-terminal his-tagged LDHB (1 to 333) expressed in insect cells using pyruvate as substrate after 10 mins by UV...				Bioorg Med Chem Lett 23: 3186-94 (2013) Article DOI: 10.1016/j.bmcl.2013.04.001 BindingDB Entry DOI: 10.7270/Q29C6ZTT
					More data for this Ligand-Target Pair				3D Structure (crystal)
L-lactate dehydrogenase B chain   (326/333 = 98%)† (Mus musculus (Mouse))	BDBM23222 (Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Ac...) Show SMILES NC(=O)C(O)=O Show InChI InChI=1S/C2H3NO3/c3-1(4)2(5)6/h(H2,3,4)(H,5,6)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	7.4	n/a
Instituto Politécnico Nacional					Assay Description Lactate dehydrogenase activity was determined by recording the absorbance change at 340 nm produced by the oxidation of NADH. Assays were performed a...				J Enzyme Inhib Med Chem 26: 579-86 (2011) Article DOI: 10.3109/14756366.2011.566221 BindingDB Entry DOI: 10.7270/Q2R78D36
					More data for this Ligand-Target Pair				3D Structure (crystal)
L-lactate dehydrogenase B chain   (327/333 = 98%)† (Bos taurus (bovine))	BDBM23222 (Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Ac...) Show SMILES NC(=O)C(O)=O Show InChI InChI=1S/C2H3NO3/c3-1(4)2(5)6/h(H2,3,4)(H,5,6)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	1.23E+5	n/a	n/a	n/a	n/a	7.0	25
University of Mississippi					Assay Description LDH was assayed spectrophotometrically for reduction of pyruvate using NADH by recording the changed in absorbance at 340 nm. The reaction was initia...				J Med Chem 50: 3841-50 (2007) Article DOI: 10.1021/jm070336k BindingDB Entry DOI: 10.7270/Q2HH6HCV
					More data for this Ligand-Target Pair				3D Structure (crystal)

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