Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Galectin-3 (138/138 = 100%)† (Homo sapiens (Human)) | BDBM50370453 (LACTOSE | Lactose, anhydrous) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 9.26E+4 | n/a | n/a | n/a | n/a | n/a |
FCFRP - USP Curated by ChEMBL | Assay Description Inhibition of human recombinant wild type galectin 3 after 60 mins by surface plasmon resonance immunosensor assay | Bioorg Med Chem 23: 3414-25 (2015) Article DOI: 10.1016/j.bmc.2015.04.044 BindingDB Entry DOI: 10.7270/Q2028T8V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (138/138 = 100%)† (Homo sapiens (Human)) | BDBM50370453 (LACTOSE | Lactose, anhydrous) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.10E+5 | n/a | n/a | n/a | n/a | n/a |
Lund University Curated by ChEMBL | Assay Description Binding affinity to galectin 3 at 20 degC by fluorescence polarization assay | J Med Chem 51: 8109-14 (2008) Article DOI: 10.1021/jm801077j BindingDB Entry DOI: 10.7270/Q29W0GDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (120/138 = 87%)† (Mus musculus) | BDBM50370453 (LACTOSE | Lactose, anhydrous) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.22E+5 | n/a | n/a | n/a | n/a | n/a |
Lund University Curated by ChEMBL | Assay Description Dissociation constant for mouse Galectin-3 | Bioorg Med Chem Lett 15: 3344-6 (2005) Article DOI: 10.1016/j.bmcl.2005.05.084 BindingDB Entry DOI: 10.7270/Q2D79C6D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (138/138 = 100%)† (Homo sapiens (Human)) | BDBM50370453 (LACTOSE | Lactose, anhydrous) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.30E+5 | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutical Research and Development, LLC Curated by ChEMBL | Assay Description Binding affinity to galectin-3 (unknown origin) | J Med Chem 57: 7819-37 (2014) Article DOI: 10.1021/jm500325k BindingDB Entry DOI: 10.7270/Q2JW8GH3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (138/138 = 100%)† (Homo sapiens (Human)) | BDBM50370453 (LACTOSE | Lactose, anhydrous) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 8.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ du Qu£bec£ Montr£al Curated by ChEMBL | Assay Description Inhibition of recombinant galectin 3 in human O type red blood cells by hemagglutination assay | Bioorg Med Chem 16: 7811-23 (2008) Article DOI: 10.1016/j.bmc.2008.06.044 BindingDB Entry DOI: 10.7270/Q2HQ40TS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (120/138 = 87%)† (Mus musculus) | BDBM50370453 (LACTOSE | Lactose, anhydrous) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Physiological Chemistry, Faculty of Veterinary Medicine, Ludwig-Maximilians-University Munich, Veterinärstr. 13, 80539 München, Germany. Curated by ChEMBL | Assay Description Inhibition of galectin-3 in C57BL/6 mouse jejunum using SK-5100 as substrate incubated for 30 mins by VAA staining based microscopic analysis | Bioorg Med Chem 25: 3158-3170 (2017) Article DOI: 10.1016/j.bmc.2017.04.011 BindingDB Entry DOI: 10.7270/Q2PN9820 | |||||||||||
More data for this Ligand-Target Pair |