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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Casein kinase II subunit alpha (334/334 = 100%)† (Homo sapiens (Human)) | BDBM11324 ((2R,3R,4S,5R)-2-(5,6-dichloro-1H-1,3-benzodiazol-1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet  | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 4.50E+3 | -30.2 | n/a | n/a | n/a | n/a | n/a | 7.5 | 22 |
University of Padova | Assay Description In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam... | Biochem J 374: 639-46 (2003) Article DOI: 10.1042/BJ20030674 BindingDB Entry DOI: 10.7270/Q2BV7DTQ | |||||||||||
| More data for this Ligand-Target Pair |  3D Structure (crystal) | ||||||||||||
| Casein kinase II subunit alpha (334/334 = 100%)† (Homo sapiens (Human)) | BDBM11324 ((2R,3R,4S,5R)-2-(5,6-dichloro-1H-1,3-benzodiazol-1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Osaka Prefecture University Curated by ChEMBL | Assay Description Inhibition of GST-fused human recombinant CK2alpha expressed in Escherichia coli HMS174 (DE3) | Bioorg Med Chem Lett 19: 2920-3 (2009) Article DOI: 10.1016/j.bmcl.2009.04.076 BindingDB Entry DOI: 10.7270/Q25B02CC | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
