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PDB code 4OVF

Compile Data Set for Download or QSAR

Identical Ligands in BindingDB

Found 4 hits Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta sliding clamp

  (366/366 = 100%)
(Escherichia coli (strain K12))
BDBM50096638
PNG
(CHEMBL3577268)
Show SMILES OC(=O)[C@@H]1CCc2c(C1)[nH]c1ccc(Cl)cc21 |r|
PDB

UniProtKB/SwissProt

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PDB
Article
PubMed
7.40E+4n/an/an/an/an/an/an/an/a



The University of Wollongong and The Illawarra Health and Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli DNA sliding clamp protein using N-fluorescein (FAM)-QLDLF-OH tracer by fluorescence polarization assay


J Med Chem 58: 4693-702 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00232
BindingDB Entry DOI: 10.7270/Q2KK9DJ9
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Beta sliding clamp

  (366/366 = 100%)
(Escherichia coli (strain K12))
BDBM50096641
PNG
(CHEMBL3277053)
Show SMILES OC(=O)C1CCc2c(C1)[nH]c1ccc(Cl)cc21
PDB

UniProtKB/SwissProt

GoogleScholar
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CHEMBL
PC cid
PC sid
PDB
UniChem

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PDB
Article
PubMed
1.66E+5n/an/an/an/an/an/an/an/a



The University of Wollongong and The Illawarra Health and Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli DNA sliding clamp protein using N-fluorescein (FAM)-QLDLF-OH tracer by fluorescence polarization assay


J Med Chem 58: 4693-702 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00232
BindingDB Entry DOI: 10.7270/Q2KK9DJ9
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Beta sliding clamp

  (366/366 = 100%)
(Escherichia coli (strain K12))
BDBM50096638
PNG
(CHEMBL3577268)
Show SMILES OC(=O)[C@@H]1CCc2c(C1)[nH]c1ccc(Cl)cc21 |r|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
PDB
UniChem

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Similars

PDB
Article
PubMed
n/an/a 1.34E+5n/an/an/an/an/an/a



The University of Wollongong and The Illawarra Health and Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli DNA sliding clamp protein using N-fluorescein (FAM)-QLDLF-OH tracer by fluorescence polarization assay


J Med Chem 58: 4693-702 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00232
BindingDB Entry DOI: 10.7270/Q2KK9DJ9
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Beta sliding clamp

  (366/366 = 100%)
(Escherichia coli (strain K12))
BDBM50096641
PNG
(CHEMBL3277053)
Show SMILES OC(=O)C1CCc2c(C1)[nH]c1ccc(Cl)cc21
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
PDB
UniChem

Patents


Similars

PDB
Article
PubMed
n/an/a 2.99E+5n/an/an/an/an/an/a



The University of Wollongong and The Illawarra Health and Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli DNA sliding clamp protein using N-fluorescein (FAM)-QLDLF-OH tracer by fluorescence polarization assay


J Med Chem 58: 4693-702 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00232
BindingDB Entry DOI: 10.7270/Q2KK9DJ9
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)

Search BindingMOAD for More Affinity Data:

* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
Identities from BLAST output