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PDB code 4UIY

Compile Data Set for Download or QSAR

Identical Ligands in BindingDB

Found 1 hit Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DNA topoisomerase 4 subunit A/B


(Staphylococcus aureus)
BDBM50249799
PNG
(CHEMBL4789899)
Show SMILES Cl.COC(=O)[C@H](C)NC(=O)c1ccc(NC(=O)c2[nH]c(C)c(Cl)c2Cl)c(OC2CCNCC2)c1 |r|
Show InChI InChI=1S/C18H18N2O4S/c1-12-9-13-10-15(17(24-3)11-16(13)20(2)18(12)21)19-25(22,23)14-7-5-4-6-8-14/h4-11,19H,1-3H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.70E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of BRD4 bromodomain 1 (unknown origin) incubated in dark for 30 mins by TR-FRET assay


Citation and Details

Article DOI: 10.1016/j.ejmech.2019.02.004
BindingDB Entry DOI: 10.7270/Q23J3HK1
More data for this
Ligand-Target Pair

Search BindingMOAD for More Affinity Data:

* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
Identities from BLAST output