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PubMed code 10090790

Compile data set for download or QSAR
Found 131 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074846
PNG
(CHEMBL545597 | [3-(4-Methoxy-3-phenethyloxy-phenyl...)
Show SMILES CCCN(CCC)CCCc1ccc(OC)c(OCCc2ccccc2)c1
Show InChI InChI=1S/C24H35NO2/c1-4-16-25(17-5-2)18-9-12-22-13-14-23(26-3)24(20-22)27-19-15-21-10-7-6-8-11-21/h6-8,10-11,13-14,20H,4-5,9,12,15-19H2,1-3H3
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n/an/a 1n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074867
PNG
((2-{4-Methoxy-3-[2-(4-methoxy-phenyl)-ethoxy]-phen...)
Show SMILES CCCN(CCC)CCc1ccc(OC)c(OCCc2ccc(OC)cc2)c1
Show InChI InChI=1S/C24H35NO3/c1-5-15-25(16-6-2)17-13-21-9-12-23(27-4)24(19-21)28-18-14-20-7-10-22(26-3)11-8-20/h7-12,19H,5-6,13-18H2,1-4H3
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n/an/a 1n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074866
PNG
((2-{3-[2-(4-Fluoro-phenyl)-ethoxy]-4-methoxy-pheny...)
Show SMILES CCCN(CCC)CCc1ccc(OC)c(OCCc2ccc(F)cc2)c1
Show InChI InChI=1S/C23H32FNO2/c1-4-14-25(15-5-2)16-12-20-8-11-22(26-3)23(18-20)27-17-13-19-6-9-21(24)10-7-19/h6-11,18H,4-5,12-17H2,1-3H3
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n/an/a 1n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50170660
PNG
(CHEMBL190883 | CHEMBL521582 | N,N-dipropyl-2-[4-me...)
Show SMILES CCCN(CCC)CCc1ccc(OC)c(OCCc2ccccc2)c1
Show InChI InChI=1S/C23H33NO2/c1-4-15-24(16-5-2)17-13-21-11-12-22(25-3)23(19-21)26-18-14-20-9-7-6-8-10-20/h6-12,19H,4-5,13-18H2,1-3H3
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n/an/a 1.30n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074859
PNG
((2-{3-[2-(3-Chloro-phenyl)-ethoxy]-4-methoxy-pheny...)
Show SMILES CCCN(CCC)CCc1ccc(OC)c(OCCc2cccc(Cl)c2)c1
Show InChI InChI=1S/C23H32ClNO2/c1-4-13-25(14-5-2)15-11-20-9-10-22(26-3)23(18-20)27-16-12-19-7-6-8-21(24)17-19/h6-10,17-18H,4-5,11-16H2,1-3H3
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n/an/a 1.5n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074828
PNG
(CHEMBL11290 | {2-[3-Methoxy-2-(3-phenyl-propoxy)-p...)
Show SMILES CCCN(CCC)CCc1cccc(OC)c1OCCCc1ccccc1
Show InChI InChI=1S/C24H35NO2/c1-4-17-25(18-5-2)19-16-22-14-9-15-23(26-3)24(22)27-20-10-13-21-11-7-6-8-12-21/h6-9,11-12,14-15H,4-5,10,13,16-20H2,1-3H3
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n/an/a 1.70n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074827
PNG
(CHEMBL542298 | Hexyl-[2-(4-methoxy-3-phenethyloxy-...)
Show SMILES CCCCCCN(CCC)CCc1ccc(OC)c(OCCc2ccccc2)c1
Show InChI InChI=1S/C26H39NO2/c1-4-6-7-11-19-27(18-5-2)20-16-24-14-15-25(28-3)26(22-24)29-21-17-23-12-9-8-10-13-23/h8-10,12-15,22H,4-7,11,16-21H2,1-3H3
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n/an/a 1.80n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074839
PNG
(CHEMBL542047 | [2-(3-Methoxy-2-phenethyloxy-phenyl...)
Show SMILES CCCN(CCC)CCc1cccc(OC)c1OCCc1ccccc1
Show InChI InChI=1S/C23H33NO2/c1-4-16-24(17-5-2)18-14-21-12-9-13-22(25-3)23(21)26-19-15-20-10-7-6-8-11-20/h6-13H,4-5,14-19H2,1-3H3
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n/an/a 2.70n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074865
PNG
(CHEMBL542295 | [2-(4-Methoxy-3-phenethyloxy-phenyl...)
Show SMILES CCCN(CCC(C)C)CCc1ccc(OC)c(OCCc2ccccc2)c1
Show InChI InChI=1S/C25H37NO2/c1-5-16-26(17-13-21(2)3)18-14-23-11-12-24(27-4)25(20-23)28-19-15-22-9-7-6-8-10-22/h6-12,20-21H,5,13-19H2,1-4H3
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n/an/a 2.90n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074869
PNG
(4-(2-Dipropylamino-ethyl)-2-phenethyloxy-phenol; h...)
Show SMILES CCCN(CCC)CCc1ccc(O)c(OCCc2ccccc2)c1
Show InChI InChI=1S/C22H31NO2/c1-3-14-23(15-4-2)16-12-20-10-11-21(24)22(18-20)25-17-13-19-8-6-5-7-9-19/h5-11,18,24H,3-4,12-17H2,1-2H3
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n/an/a 3.10n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074853
PNG
(CHEMBL11182 | {2-[4-Methoxy-3-(3-phenyl-propoxy)-p...)
Show SMILES CCCN(CCC)CCc1ccc(OC)c(OCCCc2ccccc2)c1
Show InChI InChI=1S/C24H35NO2/c1-4-16-25(17-5-2)18-15-22-13-14-23(26-3)24(20-22)27-19-9-12-21-10-7-6-8-11-21/h6-8,10-11,13-14,20H,4-5,9,12,15-19H2,1-3H3
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n/an/a 4.70n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50001955
PNG
((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)
Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 |r|
Show InChI InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1
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n/an/a 5.10n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074826
PNG
(CHEMBL11774 | [2-(4-Methoxy-2-phenethyloxy-phenyl)...)
Show SMILES CCCN(CCC)CCc1ccc(OC)cc1OCCc1ccccc1
Show InChI InChI=1S/C23H33NO2/c1-4-15-24(16-5-2)17-13-21-11-12-22(25-3)19-23(21)26-18-14-20-9-7-6-8-10-20/h6-12,19H,4-5,13-18H2,1-3H3
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n/an/a 6.60n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074840
PNG
(CHEMBL11474 | [2-(2-Methoxy-4-phenethyloxy-phenyl)...)
Show SMILES CCCN(CCC)CCc1ccc(OCCc2ccccc2)cc1OC
Show InChI InChI=1S/C23H33NO2/c1-4-15-24(16-5-2)17-13-21-11-12-22(19-23(21)25-3)26-18-14-20-9-7-6-8-10-20/h6-12,19H,4-5,13-18H2,1-3H3
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n/an/a 6.80n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074856
PNG
(CHEMBL537251 | [2-(5-Methoxy-2-phenethyloxy-phenyl...)
Show SMILES CCCN(CCC)CCc1cc(OC)ccc1OCCc1ccccc1
Show InChI InChI=1S/C23H33NO2/c1-4-15-24(16-5-2)17-13-21-19-22(25-3)11-12-23(21)26-18-14-20-9-7-6-8-10-20/h6-12,19H,4-5,13-18H2,1-3H3
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n/an/a 7.10n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074850
PNG
(CHEMBL11803 | [2-(5-Chloro-2-phenethyloxy-phenyl)-...)
Show SMILES CCCN(CCC)CCc1cc(Cl)ccc1OCCc1ccccc1
Show InChI InChI=1S/C22H30ClNO/c1-3-14-24(15-4-2)16-12-20-18-21(23)10-11-22(20)25-17-13-19-8-6-5-7-9-19/h5-11,18H,3-4,12-17H2,1-2H3
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n/an/a 7.20n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074873
PNG
(CHEMBL542049 | {2-[4-Methoxy-3-(2-thiophen-2-yl-et...)
Show SMILES CCCN(CCC)CCc1ccc(OC)c(OCCc2cccs2)c1
Show InChI InChI=1S/C21H31NO2S/c1-4-12-22(13-5-2)14-10-18-8-9-20(23-3)21(17-18)24-15-11-19-7-6-16-25-19/h6-9,16-17H,4-5,10-15H2,1-3H3
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n/an/a 9.40n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074844
PNG
(CHEMBL11279 | [2-(5-Bromo-2-phenethyloxy-phenyl)-e...)
Show SMILES CCCN(CCC)CCc1cc(Br)ccc1OCCc1ccccc1
Show InChI InChI=1S/C22H30BrNO/c1-3-14-24(15-4-2)16-12-20-18-21(23)10-11-22(20)25-17-13-19-8-6-5-7-9-19/h5-11,18H,3-4,12-17H2,1-2H3
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n/an/a 11n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074872
PNG
(1-[2-(4-Methoxy-3-phenethyloxy-phenyl)-ethyl]-4-(2...)
Show SMILES COc1ccc(CCN2CCN(CC2)c2ccccc2OC)cc1OCCc1ccccc1
Show InChI InChI=1S/C28H34N2O3/c1-31-26-11-7-6-10-25(26)30-19-17-29(18-20-30)16-14-24-12-13-27(32-2)28(22-24)33-21-15-23-8-4-3-5-9-23/h3-13,22H,14-21H2,1-2H3
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n/an/a 11n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074880
PNG
(CHEMBL269638 | [3-(5-Bromo-2-phenethyloxy-phenyl)-...)
Show SMILES CCCN(CCC)CCCc1cc(Br)ccc1OCCc1ccccc1
Show InChI InChI=1S/C23H32BrNO/c1-3-15-25(16-4-2)17-8-11-21-19-22(24)12-13-23(21)26-18-14-20-9-6-5-7-10-20/h5-7,9-10,12-13,19H,3-4,8,11,14-18H2,1-2H3
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n/an/a 11n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074830
PNG
(CHEMBL11894 | [2-(3-Methoxy-4-phenethyloxy-phenyl)...)
Show SMILES CCCN(CCC)CCc1ccc(OCCc2ccccc2)c(OC)c1
Show InChI InChI=1S/C23H33NO2/c1-4-15-24(16-5-2)17-13-21-11-12-22(23(19-21)25-3)26-18-14-20-9-7-6-8-10-20/h6-12,19H,4-5,13-18H2,1-3H3
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n/an/a 12n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074831
PNG
(CHEMBL543015 | [2-(5-Fluoro-2-phenethyloxy-phenyl)...)
Show SMILES CCCN(CCC)CCc1cc(F)ccc1OCCc1ccccc1
Show InChI InChI=1S/C22H30FNO/c1-3-14-24(15-4-2)16-12-20-18-21(23)10-11-22(20)25-17-13-19-8-6-5-7-9-19/h5-11,18H,3-4,12-17H2,1-2H3
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n/an/a 13n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074879
PNG
(CHEMBL275948 | [3-(3-Methoxy-2-phenethyloxy-phenyl...)
Show SMILES CCCN(CCC)CCCc1cccc(OC)c1OCCc1ccccc1
Show InChI InChI=1S/C24H35NO2/c1-4-17-25(18-5-2)19-10-14-22-13-9-15-23(26-3)24(22)27-20-16-21-11-7-6-8-12-21/h6-9,11-13,15H,4-5,10,14,16-20H2,1-3H3
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n/an/a 13n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074838
PNG
(CHEMBL276007 | [2-(2-Phenethyloxy-phenyl)-ethyl]-d...)
Show SMILES CCCN(CCC)CCc1ccccc1OCCc1ccccc1
Show InChI InChI=1S/C22H31NO/c1-3-16-23(17-4-2)18-14-21-12-8-9-13-22(21)24-19-15-20-10-6-5-7-11-20/h5-13H,3-4,14-19H2,1-2H3
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n/an/a 15n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074871
PNG
(1-[3-(5-Chloro-2-phenethyloxy-phenyl)-propyl]-4-(2...)
Show SMILES COc1ccccc1N1CCN(CCCc2cc(Cl)ccc2OCCc2ccccc2)CC1
Show InChI InChI=1S/C28H33ClN2O2/c1-32-28-12-6-5-11-26(28)31-19-17-30(18-20-31)16-7-10-24-22-25(29)13-14-27(24)33-21-15-23-8-3-2-4-9-23/h2-6,8-9,11-14,22H,7,10,15-21H2,1H3
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n/an/a 16n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074851
PNG
(CHEMBL542048 | [2-(4-Chloro-2-phenethyloxy-phenyl)...)
Show SMILES CCCN(CCC)CCc1ccc(Cl)cc1OCCc1ccccc1
Show InChI InChI=1S/C22H30ClNO/c1-3-14-24(15-4-2)16-12-20-10-11-21(23)18-22(20)25-17-13-19-8-6-5-7-9-19/h5-11,18H,3-4,12-17H2,1-2H3
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n/an/a 18n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074854
PNG
(3-{[2-(4-Methoxy-3-phenethyloxy-phenyl)-ethyl]-pro...)
Show SMILES CCCN(CCCO)CCc1ccc(OC)c(OCCc2ccccc2)c1
Show InChI InChI=1S/C23H33NO3/c1-3-14-24(15-7-17-25)16-12-21-10-11-22(26-2)23(19-21)27-18-13-20-8-5-4-6-9-20/h4-6,8-11,19,25H,3,7,12-18H2,1-2H3
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n/an/a 19n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074842
PNG
(CHEMBL11535 | [2-(3-Fluoro-2-phenethyloxy-phenyl)-...)
Show SMILES CCCN(CCC)CCc1cccc(F)c1OCCc1ccccc1
Show InChI InChI=1S/C22H30FNO/c1-3-15-24(16-4-2)17-13-20-11-8-12-21(23)22(20)25-18-14-19-9-6-5-7-10-19/h5-12H,3-4,13-18H2,1-2H3
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n/an/a 22n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074872
PNG
(1-[2-(4-Methoxy-3-phenethyloxy-phenyl)-ethyl]-4-(2...)
Show SMILES COc1ccc(CCN2CCN(CC2)c2ccccc2OC)cc1OCCc1ccccc1
Show InChI InChI=1S/C28H34N2O3/c1-31-26-11-7-6-10-25(26)30-19-17-29(18-20-30)16-14-24-12-13-27(32-2)28(22-24)33-21-15-23-8-4-3-5-9-23/h3-13,22H,14-21H2,1-2H3
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n/an/a 25n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074835
PNG
(5-(2-Dipropylamino-ethyl)-2-phenethyloxy-phenol; h...)
Show SMILES CCCN(CCC)CCc1ccc(OCCc2ccccc2)c(O)c1
Show InChI InChI=1S/C22H31NO2/c1-3-14-23(15-4-2)16-12-20-10-11-22(21(24)18-20)25-17-13-19-8-6-5-7-9-19/h5-11,18,24H,3-4,12-17H2,1-2H3
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n/an/a 25n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074883
PNG
(CHEMBL262955 | [2-(2-Benzyloxy-3-methoxy-phenyl)-e...)
Show SMILES CCCN(CCC)CCc1cccc(OC)c1OCc1ccccc1
Show InChI InChI=1S/C22H31NO2/c1-4-15-23(16-5-2)17-14-20-12-9-13-21(24-3)22(20)25-18-19-10-7-6-8-11-19/h6-13H,4-5,14-18H2,1-3H3
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n/an/a 26n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074875
PNG
(CHEMBL11657 | [4-(5-Chloro-2-phenethyloxy-phenyl)-...)
Show SMILES CCCN(CCC)CCCCc1cc(Cl)ccc1OCCc1ccccc1
Show InChI InChI=1S/C24H34ClNO/c1-3-16-26(17-4-2)18-9-8-12-22-20-23(25)13-14-24(22)27-19-15-21-10-6-5-7-11-21/h5-7,10-11,13-14,20H,3-4,8-9,12,15-19H2,1-2H3
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n/an/a 26n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074852
PNG
(CHEMBL11598 | [2-(3-Benzyloxy-4-methoxy-phenyl)-et...)
Show SMILES CCCN(CCC)CCc1ccc(OC)c(OCc2ccccc2)c1
Show InChI InChI=1S/C22H31NO2/c1-4-14-23(15-5-2)16-13-19-11-12-21(24-3)22(17-19)25-18-20-9-7-6-8-10-20/h6-12,17H,4-5,13-16,18H2,1-3H3
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n/an/a 28n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074843
PNG
(1-[2-(3-Methoxy-2-phenethyloxy-phenyl)-ethyl]-pyrr...)
Show SMILES COc1cccc(CCN2CCCC2)c1OCCc1ccccc1
Show InChI InChI=1S/C21H27NO2/c1-23-20-11-7-10-19(12-16-22-14-5-6-15-22)21(20)24-17-13-18-8-3-2-4-9-18/h2-4,7-11H,5-6,12-17H2,1H3
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n/an/a 28n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074881
PNG
(1-[2-(4-Methoxy-3-phenethyloxy-phenyl)-ethyl]-4-ph...)
Show SMILES COc1ccc(CCN2CCN(CC2)c2ccccc2)cc1OCCc1ccccc1
Show InChI InChI=1S/C27H32N2O2/c1-30-26-13-12-24(22-27(26)31-21-15-23-8-4-2-5-9-23)14-16-28-17-19-29(20-18-28)25-10-6-3-7-11-25/h2-13,22H,14-21H2,1H3
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n/an/a 33n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074857
PNG
(CHEMBL542786 | [2-(4-Methoxy-3-phenethyloxy-phenyl...)
Show SMILES CCCNCCc1ccc(OC)c(OCCc2ccccc2)c1
Show InChI InChI=1S/C20H27NO2/c1-3-13-21-14-11-18-9-10-19(22-2)20(16-18)23-15-12-17-7-5-4-6-8-17/h4-10,16,21H,3,11-15H2,1-2H3
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n/an/a 34n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074863
PNG
(1-[2-(5-Chloro-2-phenethyloxy-phenyl)-ethyl]-pyrro...)
Show SMILES Clc1ccc(OCCc2ccccc2)c(CCN2CCCC2)c1
Show InChI InChI=1S/C20H24ClNO/c21-19-8-9-20(23-15-11-17-6-2-1-3-7-17)18(16-19)10-14-22-12-4-5-13-22/h1-3,6-9,16H,4-5,10-15H2
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n/an/a 36n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074860
PNG
(CHEMBL11231 | {2-[5-Bromo-2-(3-phenyl-propoxy)-phe...)
Show SMILES CCCN(CCC)CCc1cc(Br)ccc1OCCCc1ccccc1
Show InChI InChI=1S/C23H32BrNO/c1-3-15-25(16-4-2)17-14-21-19-22(24)12-13-23(21)26-18-8-11-20-9-6-5-7-10-20/h5-7,9-10,12-13,19H,3-4,8,11,14-18H2,1-2H3
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n/an/a 44n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074868
PNG
(1-[2-(5-Chloro-2-phenethyloxy-phenyl)-ethyl]-4-pyr...)
Show SMILES Clc1ccc(OCCc2ccccc2)c(CCN2CCN(CC2)c2ccccn2)c1
Show InChI InChI=1S/C25H28ClN3O/c26-23-9-10-24(30-19-12-21-6-2-1-3-7-21)22(20-23)11-14-28-15-17-29(18-16-28)25-8-4-5-13-27-25/h1-10,13,20H,11-12,14-19H2
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n/an/a 51n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074849
PNG
(CHEMBL11740 | {2-[5-Chloro-2-(3-phenyl-propoxy)-ph...)
Show SMILES CCCN(CCC)CCc1cc(Cl)ccc1OCCCc1ccccc1
Show InChI InChI=1S/C23H32ClNO/c1-3-15-25(16-4-2)17-14-21-19-22(24)12-13-23(21)26-18-8-11-20-9-6-5-7-10-20/h5-7,9-10,12-13,19H,3-4,8,11,14-18H2,1-2H3
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n/an/a 56n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074841
PNG
(1-[2-(3-Methoxy-2-phenethyloxy-phenyl)-ethyl]-4-ph...)
Show SMILES COc1cccc(CCN2CCN(CC2)c2ccccc2)c1OCCc1ccccc1
Show InChI InChI=1S/C27H32N2O2/c1-30-26-14-8-11-24(27(26)31-22-16-23-9-4-2-5-10-23)15-17-28-18-20-29(21-19-28)25-12-6-3-7-13-25/h2-14H,15-22H2,1H3
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n/an/a 66n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074877
PNG
((2-{3-[2-(3,4-Dimethoxy-phenyl)-ethoxy]-4-methoxy-...)
Show SMILES CCCN(CCC)CCc1ccc(OC)c(OCCc2ccc(OC)c(OC)c2)c1
Show InChI InChI=1S/C25H37NO4/c1-6-14-26(15-7-2)16-12-20-8-11-23(28-4)25(19-20)30-17-13-21-9-10-22(27-3)24(18-21)29-5/h8-11,18-19H,6-7,12-17H2,1-5H3
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n/an/a 67n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074863
PNG
(1-[2-(5-Chloro-2-phenethyloxy-phenyl)-ethyl]-pyrro...)
Show SMILES Clc1ccc(OCCc2ccccc2)c(CCN2CCCC2)c1
Show InChI InChI=1S/C20H24ClNO/c21-19-8-9-20(23-15-11-17-6-2-1-3-7-17)18(16-19)10-14-22-12-4-5-13-22/h1-3,6-9,16H,4-5,10-15H2
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n/an/a 69n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074836
PNG
(1-[2-(5-Chloro-2-phenethyloxy-phenyl)-ethyl]-4-(2-...)
Show SMILES COc1ccccc1N1CCN(CCc2cc(Cl)ccc2OCCc2ccccc2)CC1
Show InChI InChI=1S/C27H31ClN2O2/c1-31-27-10-6-5-9-25(27)30-18-16-29(17-19-30)15-13-23-21-24(28)11-12-26(23)32-20-14-22-7-3-2-4-8-22/h2-12,21H,13-20H2,1H3
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n/an/a 88n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074837
PNG
(1-[3-(5-Chloro-2-phenethyloxy-phenyl)-propyl]-4-py...)
Show SMILES Clc1ccc(OCCc2ccccc2)c(CCCN2CCN(CC2)c2ccccn2)c1
Show InChI InChI=1S/C26H30ClN3O/c27-24-11-12-25(31-20-13-22-7-2-1-3-8-22)23(21-24)9-6-15-29-16-18-30(19-17-29)26-10-4-5-14-28-26/h1-5,7-8,10-12,14,21H,6,9,13,15-20H2
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n/an/a 93n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074855
PNG
(1-[2-(4-Methoxy-3-phenethyloxy-phenyl)-ethyl]-pyrr...)
Show SMILES COc1ccc(CCN2CCCC2)cc1OCCc1ccccc1
Show InChI InChI=1S/C21H27NO2/c1-23-20-10-9-19(11-15-22-13-5-6-14-22)17-21(20)24-16-12-18-7-3-2-4-8-18/h2-4,7-10,17H,5-6,11-16H2,1H3
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n/an/a 107n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074864
PNG
(1-[2-(4-Methoxy-3-phenethyloxy-phenyl)-ethyl]-4-py...)
Show SMILES COc1ccc(CCN2CCN(CC2)c2ccccn2)cc1OCCc1ccccc1
Show InChI InChI=1S/C26H31N3O2/c1-30-24-11-10-23(21-25(24)31-20-13-22-7-3-2-4-8-22)12-15-28-16-18-29(19-17-28)26-9-5-6-14-27-26/h2-11,14,21H,12-13,15-20H2,1H3
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n/an/a 112n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074850
PNG
(CHEMBL11803 | [2-(5-Chloro-2-phenethyloxy-phenyl)-...)
Show SMILES CCCN(CCC)CCc1cc(Cl)ccc1OCCc1ccccc1
Show InChI InChI=1S/C22H30ClNO/c1-3-14-24(15-4-2)16-12-20-18-21(23)10-11-22(20)25-17-13-19-8-6-5-7-9-19/h5-11,18H,3-4,12-17H2,1-2H3
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n/an/a 112n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074876
PNG
(2-{4-[3-(5-Chloro-2-phenethyloxy-phenyl)-propyl]-p...)
Show SMILES Clc1ccc(OCCc2ccccc2)c(CCCN2CCN(CC2)c2ncccn2)c1
Show InChI InChI=1S/C25H29ClN4O/c26-23-9-10-24(31-19-11-21-6-2-1-3-7-21)22(20-23)8-4-14-29-15-17-30(18-16-29)25-27-12-5-13-28-25/h1-3,5-7,9-10,12-13,20H,4,8,11,14-19H2
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n/an/a 115n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074858
PNG
(CHEMBL11675 | [2-(2-Benzyloxy-5-chloro-phenyl)-eth...)
Show SMILES CCCN(CCC)CCc1cc(Cl)ccc1OCc1ccccc1
Show InChI InChI=1S/C21H28ClNO/c1-3-13-23(14-4-2)15-12-19-16-20(22)10-11-21(19)24-17-18-8-6-5-7-9-18/h5-11,16H,3-4,12-15,17H2,1-2H3
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n/an/a 118n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074837
PNG
(1-[3-(5-Chloro-2-phenethyloxy-phenyl)-propyl]-4-py...)
Show SMILES Clc1ccc(OCCc2ccccc2)c(CCCN2CCN(CC2)c2ccccn2)c1
Show InChI InChI=1S/C26H30ClN3O/c27-24-11-12-25(31-20-13-22-7-2-1-3-8-22)23(21-24)9-6-15-29-16-18-30(19-17-29)26-10-4-5-14-28-26/h1-5,7-8,10-12,14,21H,6,9,13,15-20H2
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n/an/a 118n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074862
PNG
(1-[2-(3-Methoxy-2-phenethyloxy-phenyl)-ethyl]-4-py...)
Show SMILES COc1cccc(CCN2CCN(CC2)c2ccccn2)c1OCCc1ccccc1
Show InChI InChI=1S/C26H31N3O2/c1-30-24-11-7-10-23(26(24)31-21-14-22-8-3-2-4-9-22)13-16-28-17-19-29(20-18-28)25-12-5-6-15-27-25/h2-12,15H,13-14,16-21H2,1H3
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n/an/a 137n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074861
PNG
(1-[3-(5-Chloro-2-phenethyloxy-phenyl)-propyl]-4-ph...)
Show SMILES Clc1ccc(OCCc2ccccc2)c(CCCN2CCN(CC2)c2ccccc2)c1
Show InChI InChI=1S/C27H31ClN2O/c28-25-13-14-27(31-21-15-23-8-3-1-4-9-23)24(22-25)10-7-16-29-17-19-30(20-18-29)26-11-5-2-6-12-26/h1-6,8-9,11-14,22H,7,10,15-21H2
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n/an/a 142n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074870
PNG
(2-{4-[2-(5-Chloro-2-phenethyloxy-phenyl)-ethyl]-pi...)
Show SMILES Clc1ccc(OCCc2ccccc2)c(CCN2CCN(CC2)c2ncccn2)c1
Show InChI InChI=1S/C24H27ClN4O/c25-22-7-8-23(30-18-10-20-5-2-1-3-6-20)21(19-22)9-13-28-14-16-29(17-15-28)24-26-11-4-12-27-24/h1-8,11-12,19H,9-10,13-18H2
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n/an/a 143n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50002238
PNG
((R)1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-...)
Show SMILES OC(CCCN1CCN(CC1)c1ncc(F)cn1)c1ccc(F)cc1
Show InChI InChI=1S/C18H22F2N4O/c19-15-5-3-14(4-6-15)17(25)2-1-7-23-8-10-24(11-9-23)18-21-12-16(20)13-22-18/h3-6,12-13,17,25H,1-2,7-11H2
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n/an/a 158n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074874
PNG
(4-[2-(5-Chloro-2-phenethyloxy-phenyl)-ethyl]-morph...)
Show SMILES Clc1ccc(OCCc2ccccc2)c(CCN2CCOCC2)c1
Show InChI InChI=1S/C20H24ClNO2/c21-19-6-7-20(24-13-9-17-4-2-1-3-5-17)18(16-19)8-10-22-11-14-23-15-12-22/h1-7,16H,8-15H2
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n/an/a 163n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074844
PNG
(CHEMBL11279 | [2-(5-Bromo-2-phenethyloxy-phenyl)-e...)
Show SMILES CCCN(CCC)CCc1cc(Br)ccc1OCCc1ccccc1
Show InChI InChI=1S/C22H30BrNO/c1-3-14-24(15-4-2)16-12-20-18-21(23)10-11-22(20)25-17-13-19-8-6-5-7-9-19/h5-11,18H,3-4,12-17H2,1-2H3
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n/an/a 169n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074876
PNG
(2-{4-[3-(5-Chloro-2-phenethyloxy-phenyl)-propyl]-p...)
Show SMILES Clc1ccc(OCCc2ccccc2)c(CCCN2CCN(CC2)c2ncccn2)c1
Show InChI InChI=1S/C25H29ClN4O/c26-23-9-10-24(31-19-11-21-6-2-1-3-7-21)22(20-23)8-4-14-29-15-17-30(18-16-29)25-27-12-5-13-28-25/h1-3,5-7,9-10,12-13,20H,4,8,11,14-19H2
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n/an/a 169n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074861
PNG
(1-[3-(5-Chloro-2-phenethyloxy-phenyl)-propyl]-4-ph...)
Show SMILES Clc1ccc(OCCc2ccccc2)c(CCCN2CCN(CC2)c2ccccc2)c1
Show InChI InChI=1S/C27H31ClN2O/c28-25-13-14-27(31-21-15-23-8-3-1-4-9-23)24(22-25)10-7-16-29-17-19-30(20-18-29)26-11-5-2-6-12-26/h1-6,8-9,11-14,22H,7,10,15-21H2
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n/an/a 180n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074881
PNG
(1-[2-(4-Methoxy-3-phenethyloxy-phenyl)-ethyl]-4-ph...)
Show SMILES COc1ccc(CCN2CCN(CC2)c2ccccc2)cc1OCCc1ccccc1
Show InChI InChI=1S/C27H32N2O2/c1-30-26-13-12-24(22-27(26)31-21-15-23-8-4-2-5-9-23)14-16-28-17-19-29(20-18-28)25-10-6-3-7-11-25/h2-13,22H,14-21H2,1H3
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n/an/a 183n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074834
PNG
(CHEMBL11637 | [2-(3,5-Dichloro-2-phenethyloxy-phen...)
Show SMILES CCCN(CCC)CCc1cc(Cl)cc(Cl)c1OCCc1ccccc1
Show InChI InChI=1S/C22H29Cl2NO/c1-3-12-25(13-4-2)14-10-19-16-20(23)17-21(24)22(19)26-15-11-18-8-6-5-7-9-18/h5-9,16-17H,3-4,10-15H2,1-2H3
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n/an/a 281n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50074850
PNG
(CHEMBL11803 | [2-(5-Chloro-2-phenethyloxy-phenyl)-...)
Show SMILES CCCN(CCC)CCc1cc(Cl)ccc1OCCc1ccccc1
Show InChI InChI=1S/C22H30ClNO/c1-3-14-24(15-4-2)16-12-20-18-21(23)10-11-22(20)25-17-13-19-8-6-5-7-9-19/h5-11,18H,3-4,12-17H2,1-2H3
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n/an/a 289n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]hydroxy-2-(di-n-propylamino)-tetralin binding to 5-hydroxytryptamine 1A receptor in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074882
PNG
(1-[3-(5-Chloro-2-phenethyloxy-phenyl)-propyl]-4-(6...)
Show SMILES Cc1cccc(n1)N1CCN(CCCc2cc(Cl)ccc2OCCc2ccccc2)CC1
Show InChI InChI=1S/C27H32ClN3O/c1-22-7-5-11-27(29-22)31-18-16-30(17-19-31)15-6-10-24-21-25(28)12-13-26(24)32-20-14-23-8-3-2-4-9-23/h2-5,7-9,11-13,21H,6,10,14-20H2,1H3
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n/an/a 293n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074864
PNG
(1-[2-(4-Methoxy-3-phenethyloxy-phenyl)-ethyl]-4-py...)
Show SMILES COc1ccc(CCN2CCN(CC2)c2ccccn2)cc1OCCc1ccccc1
Show InChI InChI=1S/C26H31N3O2/c1-30-24-11-10-23(21-25(24)31-20-13-22-7-3-2-4-8-22)12-15-28-16-18-29(19-17-28)26-9-5-6-14-27-26/h2-11,14,21H,12-13,15-20H2,1H3
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n/an/a 295n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074874
PNG
(4-[2-(5-Chloro-2-phenethyloxy-phenyl)-ethyl]-morph...)
Show SMILES Clc1ccc(OCCc2ccccc2)c(CCN2CCOCC2)c1
Show InChI InChI=1S/C20H24ClNO2/c21-19-6-7-20(24-13-9-17-4-2-1-3-5-17)18(16-19)8-10-22-11-14-23-15-12-22/h1-7,16H,8-15H2
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n/an/a 308n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074871
PNG
(1-[3-(5-Chloro-2-phenethyloxy-phenyl)-propyl]-4-(2...)
Show SMILES COc1ccccc1N1CCN(CCCc2cc(Cl)ccc2OCCc2ccccc2)CC1
Show InChI InChI=1S/C28H33ClN2O2/c1-32-28-12-6-5-11-26(28)31-19-17-30(18-20-31)16-7-10-24-22-25(29)13-14-27(24)33-21-15-23-8-3-2-4-9-23/h2-6,8-9,11-14,22H,7,10,15-21H2,1H3
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n/an/a 319n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074841
PNG
(1-[2-(3-Methoxy-2-phenethyloxy-phenyl)-ethyl]-4-ph...)
Show SMILES COc1cccc(CCN2CCN(CC2)c2ccccc2)c1OCCc1ccccc1
Show InChI InChI=1S/C27H32N2O2/c1-30-26-14-8-11-24(27(26)31-22-16-23-9-4-2-5-10-23)15-17-28-18-20-29(21-19-28)25-12-6-3-7-13-25/h2-14H,15-22H2,1H3
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n/an/a 328n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074858
PNG
(CHEMBL11675 | [2-(2-Benzyloxy-5-chloro-phenyl)-eth...)
Show SMILES CCCN(CCC)CCc1cc(Cl)ccc1OCc1ccccc1
Show InChI InChI=1S/C21H28ClNO/c1-3-13-23(14-4-2)15-12-19-16-20(22)10-11-21(19)24-17-18-8-6-5-7-9-18/h5-11,16H,3-4,12-15,17H2,1-2H3
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n/an/a 337n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50074846
PNG
(CHEMBL545597 | [3-(4-Methoxy-3-phenethyloxy-phenyl...)
Show SMILES CCCN(CCC)CCCc1ccc(OC)c(OCCc2ccccc2)c1
Show InChI InChI=1S/C24H35NO2/c1-4-16-25(17-5-2)18-9-12-22-13-14-23(26-3)24(20-22)27-19-15-21-10-7-6-8-11-21/h6-8,10-11,13-14,20H,4-5,9,12,15-19H2,1-3H3
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n/an/a 373n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]hydroxy-2-(di-n-propylamino)-tetralin binding to 5-hydroxytryptamine 1A receptor in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074829
PNG
(4-[2-(3-Methoxy-2-phenethyloxy-phenyl)-ethyl]-morp...)
Show SMILES COc1cccc(CCN2CCOCC2)c1OCCc1ccccc1
Show InChI InChI=1S/C21H27NO3/c1-23-20-9-5-8-19(10-12-22-13-16-24-17-14-22)21(20)25-15-11-18-6-3-2-4-7-18/h2-9H,10-17H2,1H3
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n/an/a 373n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074882
PNG
(1-[3-(5-Chloro-2-phenethyloxy-phenyl)-propyl]-4-(6...)
Show SMILES Cc1cccc(n1)N1CCN(CCCc2cc(Cl)ccc2OCCc2ccccc2)CC1
Show InChI InChI=1S/C27H32ClN3O/c1-22-7-5-11-27(29-22)31-18-16-30(17-19-31)15-6-10-24-21-25(28)12-13-26(24)32-20-14-23-8-3-2-4-9-23/h2-5,7-9,11-13,21H,6,10,14-20H2,1H3
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n/an/a 415n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074838
PNG
(CHEMBL276007 | [2-(2-Phenethyloxy-phenyl)-ethyl]-d...)
Show SMILES CCCN(CCC)CCc1ccccc1OCCc1ccccc1
Show InChI InChI=1S/C22H31NO/c1-3-16-23(17-4-2)18-14-21-12-8-9-13-22(21)24-19-15-20-10-6-5-7-11-20/h5-13H,3-4,14-19H2,1-2H3
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n/an/a 436n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074880
PNG
(CHEMBL269638 | [3-(5-Bromo-2-phenethyloxy-phenyl)-...)
Show SMILES CCCN(CCC)CCCc1cc(Br)ccc1OCCc1ccccc1
Show InChI InChI=1S/C23H32BrNO/c1-3-15-25(16-4-2)17-8-11-21-19-22(24)12-13-23(21)26-18-14-20-9-6-5-7-10-20/h5-7,9-10,12-13,19H,3-4,8,11,14-18H2,1-2H3
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n/an/a 438n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074845
PNG
(1-(2-Dipropylamino-ethyl)-6H-benzo[c]chromen-4-ol;...)
Show SMILES CCCN(CCC)CCc1ccc(O)c2OCc3ccccc3-c12
Show InChI InChI=1S/C21H27NO2/c1-3-12-22(13-4-2)14-11-16-9-10-19(23)21-20(16)18-8-6-5-7-17(18)15-24-21/h5-10,23H,3-4,11-15H2,1-2H3
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n/an/a 558n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074827
PNG
(CHEMBL542298 | Hexyl-[2-(4-methoxy-3-phenethyloxy-...)
Show SMILES CCCCCCN(CCC)CCc1ccc(OC)c(OCCc2ccccc2)c1
Show InChI InChI=1S/C26H39NO2/c1-4-6-7-11-19-27(18-5-2)20-16-24-14-15-25(28-3)26(22-24)29-21-17-23-12-9-8-10-13-23/h8-10,12-15,22H,4-7,11,16-21H2,1-3H3
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n/an/a 619n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074836
PNG
(1-[2-(5-Chloro-2-phenethyloxy-phenyl)-ethyl]-4-(2-...)
Show SMILES COc1ccccc1N1CCN(CCc2cc(Cl)ccc2OCCc2ccccc2)CC1
Show InChI InChI=1S/C27H31ClN2O2/c1-31-27-10-6-5-9-25(27)30-18-16-29(17-19-30)15-13-23-21-24(28)11-12-26(23)32-20-14-22-7-3-2-4-8-22/h2-12,21H,13-20H2,1H3
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n/an/a 640n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074865
PNG
(CHEMBL542295 | [2-(4-Methoxy-3-phenethyloxy-phenyl...)
Show SMILES CCCN(CCC(C)C)CCc1ccc(OC)c(OCCc2ccccc2)c1
Show InChI InChI=1S/C25H37NO2/c1-5-16-26(17-13-21(2)3)18-14-23-11-12-24(27-4)25(20-23)28-19-15-22-9-7-6-8-10-22/h6-12,20-21H,5,13-19H2,1-4H3
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n/an/a 680n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074860
PNG
(CHEMBL11231 | {2-[5-Bromo-2-(3-phenyl-propoxy)-phe...)
Show SMILES CCCN(CCC)CCc1cc(Br)ccc1OCCCc1ccccc1
Show InChI InChI=1S/C23H32BrNO/c1-3-15-25(16-4-2)17-14-21-19-22(24)12-13-23(21)26-18-8-11-20-9-6-5-7-10-20/h5-7,9-10,12-13,19H,3-4,8,11,14-18H2,1-2H3
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n/an/a 685n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074847
PNG
(CHEMBL11590 | [2-(3,5-Dibromo-2-phenethyloxy-pheny...)
Show SMILES CCCN(CCC)CCc1cc(Br)cc(Br)c1OCCc1ccccc1
Show InChI InChI=1S/C22H29Br2NO/c1-3-12-25(13-4-2)14-10-19-16-20(23)17-21(24)22(19)26-15-11-18-8-6-5-7-9-18/h5-9,16-17H,3-4,10-15H2,1-2H3
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n/an/a 774n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074856
PNG
(CHEMBL537251 | [2-(5-Methoxy-2-phenethyloxy-phenyl...)
Show SMILES CCCN(CCC)CCc1cc(OC)ccc1OCCc1ccccc1
Show InChI InChI=1S/C23H33NO2/c1-4-15-24(16-5-2)17-13-21-19-22(25-3)11-12-23(21)26-18-14-20-9-7-6-8-10-20/h6-12,19H,4-5,13-18H2,1-3H3
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n/an/a 791n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074849
PNG
(CHEMBL11740 | {2-[5-Chloro-2-(3-phenyl-propoxy)-ph...)
Show SMILES CCCN(CCC)CCc1cc(Cl)ccc1OCCCc1ccccc1
Show InChI InChI=1S/C23H32ClNO/c1-3-15-25(16-4-2)17-14-21-19-22(24)12-13-23(21)26-18-8-11-20-9-6-5-7-10-20/h5-7,9-10,12-13,19H,3-4,8,11,14-18H2,1-2H3
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n/an/a 876n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074846
PNG
(CHEMBL545597 | [3-(4-Methoxy-3-phenethyloxy-phenyl...)
Show SMILES CCCN(CCC)CCCc1ccc(OC)c(OCCc2ccccc2)c1
Show InChI InChI=1S/C24H35NO2/c1-4-16-25(17-5-2)18-9-12-22-13-14-23(26-3)24(20-22)27-19-15-21-10-7-6-8-11-21/h6-8,10-11,13-14,20H,4-5,9,12,15-19H2,1-3H3
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n/an/a 950n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074825
PNG
(CHEMBL554037 | [2-(4-Methoxy-6H-benzo[c]chromen-1-...)
Show SMILES CCCN(CCC)CCc1ccc(OC)c2OCc3ccccc3-c12
Show InChI InChI=1S/C22H29NO2/c1-4-13-23(14-5-2)15-12-17-10-11-20(24-3)22-21(17)19-9-7-6-8-18(19)16-25-22/h6-11H,4-5,12-16H2,1-3H3
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n/an/a 990n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074839
PNG
(CHEMBL542047 | [2-(3-Methoxy-2-phenethyloxy-phenyl...)
Show SMILES CCCN(CCC)CCc1cccc(OC)c1OCCc1ccccc1
Show InChI InChI=1S/C23H33NO2/c1-4-16-24(17-5-2)18-14-21-12-9-13-22(25-3)23(21)26-19-15-20-10-7-6-8-11-20/h6-13H,4-5,14-19H2,1-3H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074857
PNG
(CHEMBL542786 | [2-(4-Methoxy-3-phenethyloxy-phenyl...)
Show SMILES CCCNCCc1ccc(OC)c(OCCc2ccccc2)c1
Show InChI InChI=1S/C20H27NO2/c1-3-13-21-14-11-18-9-10-19(22-2)20(16-18)23-15-12-17-7-5-4-6-8-17/h4-10,16,21H,3,11-15H2,1-2H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074867
PNG
((2-{4-Methoxy-3-[2-(4-methoxy-phenyl)-ethoxy]-phen...)
Show SMILES CCCN(CCC)CCc1ccc(OC)c(OCCc2ccc(OC)cc2)c1
Show InChI InChI=1S/C24H35NO3/c1-5-15-25(16-6-2)17-13-21-9-12-23(27-4)24(19-21)28-18-14-20-7-10-22(26-3)11-8-20/h7-12,19H,5-6,13-18H2,1-4H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074830
PNG
(CHEMBL11894 | [2-(3-Methoxy-4-phenethyloxy-phenyl)...)
Show SMILES CCCN(CCC)CCc1ccc(OCCc2ccccc2)c(OC)c1
Show InChI InChI=1S/C23H33NO2/c1-4-15-24(16-5-2)17-13-21-11-12-22(23(19-21)25-3)26-18-14-20-9-7-6-8-10-20/h6-12,19H,4-5,13-18H2,1-3H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074870
PNG
(2-{4-[2-(5-Chloro-2-phenethyloxy-phenyl)-ethyl]-pi...)
Show SMILES Clc1ccc(OCCc2ccccc2)c(CCN2CCN(CC2)c2ncccn2)c1
Show InChI InChI=1S/C24H27ClN4O/c25-22-7-8-23(30-18-10-20-5-2-1-3-6-20)21(19-22)9-13-28-14-16-29(17-15-28)24-26-11-4-12-27-24/h1-8,11-12,19H,9-10,13-18H2
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(RAT)		BDBM50170660
PNG
(CHEMBL190883 | CHEMBL521582 | N,N-dipropyl-2-[4-me...)
Show SMILES CCCN(CCC)CCc1ccc(OC)c(OCCc2ccccc2)c1
Show InChI InChI=1S/C23H33NO2/c1-4-15-24(16-5-2)17-13-21-11-12-22(25-3)23(19-21)26-18-14-20-9-7-6-8-10-20/h6-12,19H,4-5,13-18H2,1-3H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]SCH-23390 binding to Dopamine receptor D1 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074831
PNG
(CHEMBL543015 | [2-(5-Fluoro-2-phenethyloxy-phenyl)...)
Show SMILES CCCN(CCC)CCc1cc(F)ccc1OCCc1ccccc1
Show InChI InChI=1S/C22H30FNO/c1-3-14-24(15-4-2)16-12-20-18-21(23)10-11-22(20)25-17-13-19-8-6-5-7-9-19/h5-11,18H,3-4,12-17H2,1-2H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50074846
PNG
(CHEMBL545597 | [3-(4-Methoxy-3-phenethyloxy-phenyl...)
Show SMILES CCCN(CCC)CCCc1ccc(OC)c(OCCc2ccccc2)c1
Show InChI InChI=1S/C24H35NO2/c1-4-16-25(17-5-2)18-9-12-22-13-14-23(26-3)24(20-22)27-19-15-21-10-7-6-8-11-21/h6-8,10-11,13-14,20H,4-5,9,12,15-19H2,1-3H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]PCP binding to PCP site of N-methyl-D-aspartate glutamate receptor in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50074850
PNG
(CHEMBL11803 | [2-(5-Chloro-2-phenethyloxy-phenyl)-...)
Show SMILES CCCN(CCC)CCc1cc(Cl)ccc1OCCc1ccccc1
Show InChI InChI=1S/C22H30ClNO/c1-3-14-24(15-4-2)16-12-20-18-21(23)10-11-22(20)25-17-13-19-8-6-5-7-9-19/h5-11,18H,3-4,12-17H2,1-2H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]PCP binding to PCP site of N-methyl-D-aspartate glutamate receptor in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074828
PNG
(CHEMBL11290 | {2-[3-Methoxy-2-(3-phenyl-propoxy)-p...)
Show SMILES CCCN(CCC)CCc1cccc(OC)c1OCCCc1ccccc1
Show InChI InChI=1S/C24H35NO2/c1-4-17-25(18-5-2)19-16-22-14-9-15-23(26-3)24(22)27-20-10-13-21-11-7-6-8-12-21/h6-9,11-12,14-15H,4-5,10,13,16-20H2,1-3H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074840
PNG
(CHEMBL11474 | [2-(2-Methoxy-4-phenethyloxy-phenyl)...)
Show SMILES CCCN(CCC)CCc1ccc(OCCc2ccccc2)cc1OC
Show InChI InChI=1S/C23H33NO2/c1-4-15-24(16-5-2)17-13-21-11-12-22(19-23(21)25-3)26-18-14-20-9-7-6-8-10-20/h6-12,19H,4-5,13-18H2,1-3H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074842
PNG
(CHEMBL11535 | [2-(3-Fluoro-2-phenethyloxy-phenyl)-...)
Show SMILES CCCN(CCC)CCc1cccc(F)c1OCCc1ccccc1
Show InChI InChI=1S/C22H30FNO/c1-3-15-24(16-4-2)17-13-20-11-8-12-21(23)22(20)25-18-14-19-9-6-5-7-10-19/h5-12H,3-4,13-18H2,1-2H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(RAT)		BDBM50074839
PNG
(CHEMBL542047 | [2-(3-Methoxy-2-phenethyloxy-phenyl...)
Show SMILES CCCN(CCC)CCc1cccc(OC)c1OCCc1ccccc1
Show InChI InChI=1S/C23H33NO2/c1-4-16-24(17-5-2)18-14-21-12-9-13-22(25-3)23(21)26-19-15-20-10-7-6-8-11-20/h6-13H,4-5,14-19H2,1-3H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]SCH-23390 binding to Dopamine receptor D1 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074859
PNG
((2-{3-[2-(3-Chloro-phenyl)-ethoxy]-4-methoxy-pheny...)
Show SMILES CCCN(CCC)CCc1ccc(OC)c(OCCc2cccc(Cl)c2)c1
Show InChI InChI=1S/C23H32ClNO2/c1-4-13-25(14-5-2)15-11-20-9-10-22(26-3)23(18-20)27-16-12-19-7-6-8-21(24)17-19/h6-10,17-18H,4-5,11-16H2,1-3H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074826
PNG
(CHEMBL11774 | [2-(4-Methoxy-2-phenethyloxy-phenyl)...)
Show SMILES CCCN(CCC)CCc1ccc(OC)cc1OCCc1ccccc1
Show InChI InChI=1S/C23H33NO2/c1-4-15-24(16-5-2)17-13-21-11-12-22(25-3)19-23(21)26-18-14-20-9-7-6-8-10-20/h6-12,19H,4-5,13-18H2,1-3H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50001955
PNG
((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)
Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 |r|
Show InChI InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074851
PNG
(CHEMBL542048 | [2-(4-Chloro-2-phenethyloxy-phenyl)...)
Show SMILES CCCN(CCC)CCc1ccc(Cl)cc1OCCc1ccccc1
Show InChI InChI=1S/C22H30ClNO/c1-3-14-24(15-4-2)16-12-20-10-11-21(23)18-22(20)25-17-13-19-8-6-5-7-9-19/h5-11,18H,3-4,12-17H2,1-2H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074853
PNG
(CHEMBL11182 | {2-[4-Methoxy-3-(3-phenyl-propoxy)-p...)
Show SMILES CCCN(CCC)CCc1ccc(OC)c(OCCCc2ccccc2)c1
Show InChI InChI=1S/C24H35NO2/c1-4-16-25(17-5-2)18-15-22-13-14-23(26-3)24(20-22)27-19-9-12-21-10-7-6-8-11-21/h6-8,10-11,13-14,20H,4-5,9,12,15-19H2,1-3H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50170660
PNG
(CHEMBL190883 | CHEMBL521582 | N,N-dipropyl-2-[4-me...)
Show SMILES CCCN(CCC)CCc1ccc(OC)c(OCCc2ccccc2)c1
Show InChI InChI=1S/C23H33NO2/c1-4-15-24(16-5-2)17-13-21-11-12-22(25-3)23(19-21)26-18-14-20-9-7-6-8-10-20/h6-12,19H,4-5,13-18H2,1-3H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]PCP binding to PCP site of N-methyl-D-aspartate glutamate receptor in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50002238
PNG
((R)1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-...)
Show SMILES OC(CCCN1CCN(CC1)c1ncc(F)cn1)c1ccc(F)cc1
Show InChI InChI=1S/C18H22F2N4O/c19-15-5-3-14(4-6-15)17(25)2-1-7-23-8-10-24(11-9-23)18-21-12-16(20)13-22-18/h3-6,12-13,17,25H,1-2,7-11H2
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(RAT)		BDBM50074846
PNG
(CHEMBL545597 | [3-(4-Methoxy-3-phenethyloxy-phenyl...)
Show SMILES CCCN(CCC)CCCc1ccc(OC)c(OCCc2ccccc2)c1
Show InChI InChI=1S/C24H35NO2/c1-4-16-25(17-5-2)18-9-12-22-13-14-23(26-3)24(20-22)27-19-15-21-10-7-6-8-11-21/h6-8,10-11,13-14,20H,4-5,9,12,15-19H2,1-3H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]SCH-23390 binding to Dopamine receptor D1 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074834
PNG
(CHEMBL11637 | [2-(3,5-Dichloro-2-phenethyloxy-phen...)
Show SMILES CCCN(CCC)CCc1cc(Cl)cc(Cl)c1OCCc1ccccc1
Show InChI InChI=1S/C22H29Cl2NO/c1-3-12-25(13-4-2)14-10-19-16-20(23)17-21(24)22(19)26-15-11-18-8-6-5-7-9-18/h5-9,16-17H,3-4,10-15H2,1-2H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074843
PNG
(1-[2-(3-Methoxy-2-phenethyloxy-phenyl)-ethyl]-pyrr...)
Show SMILES COc1cccc(CCN2CCCC2)c1OCCc1ccccc1
Show InChI InChI=1S/C21H27NO2/c1-23-20-11-7-10-19(12-16-22-14-5-6-15-22)21(20)24-17-13-18-8-3-2-4-9-18/h2-4,7-11H,5-6,12-17H2,1H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074875
PNG
(CHEMBL11657 | [4-(5-Chloro-2-phenethyloxy-phenyl)-...)
Show SMILES CCCN(CCC)CCCCc1cc(Cl)ccc1OCCc1ccccc1
Show InChI InChI=1S/C24H34ClNO/c1-3-16-26(17-4-2)18-9-8-12-22-20-23(25)13-14-24(22)27-19-15-21-10-6-5-7-11-21/h5-7,10-11,13-14,20H,3-4,8-9,12,15-19H2,1-2H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074878
PNG
(4-[2-(4-Methoxy-3-phenethyloxy-phenyl)-ethyl]-morp...)
Show SMILES COc1ccc(CCN2CCOCC2)cc1OCCc1ccccc1
Show InChI InChI=1S/C21H27NO3/c1-23-20-8-7-19(9-11-22-12-15-24-16-13-22)17-21(20)25-14-10-18-5-3-2-4-6-18/h2-8,17H,9-16H2,1H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074829
PNG
(4-[2-(3-Methoxy-2-phenethyloxy-phenyl)-ethyl]-morp...)
Show SMILES COc1cccc(CCN2CCOCC2)c1OCCc1ccccc1
Show InChI InChI=1S/C21H27NO3/c1-23-20-9-5-8-19(10-12-22-13-16-24-17-14-22)21(20)25-15-11-18-6-3-2-4-7-18/h2-9H,10-17H2,1H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074854
PNG
(3-{[2-(4-Methoxy-3-phenethyloxy-phenyl)-ethyl]-pro...)
Show SMILES CCCN(CCCO)CCc1ccc(OC)c(OCCc2ccccc2)c1
Show InChI InChI=1S/C23H33NO3/c1-3-14-24(15-7-17-25)16-12-21-10-11-22(26-2)23(19-21)27-18-13-20-8-5-4-6-9-20/h4-6,8-11,19,25H,3,7,12-18H2,1-2H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074868
PNG
(1-[2-(5-Chloro-2-phenethyloxy-phenyl)-ethyl]-4-pyr...)
Show SMILES Clc1ccc(OCCc2ccccc2)c(CCN2CCN(CC2)c2ccccn2)c1
Show InChI InChI=1S/C25H28ClN3O/c26-23-9-10-24(30-19-12-21-6-2-1-3-7-21)22(20-23)11-14-28-15-17-29(18-16-28)25-8-4-5-13-27-25/h1-10,13,20H,11-12,14-19H2
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50170660
PNG
(CHEMBL190883 | CHEMBL521582 | N,N-dipropyl-2-[4-me...)
Show SMILES CCCN(CCC)CCc1ccc(OC)c(OCCc2ccccc2)c1
Show InChI InChI=1S/C23H33NO2/c1-4-15-24(16-5-2)17-13-21-11-12-22(25-3)23(19-21)26-18-14-20-9-7-6-8-10-20/h6-12,19H,4-5,13-18H2,1-3H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074873
PNG
(CHEMBL542049 | {2-[4-Methoxy-3-(2-thiophen-2-yl-et...)
Show SMILES CCCN(CCC)CCc1ccc(OC)c(OCCc2cccs2)c1
Show InChI InChI=1S/C21H31NO2S/c1-4-12-22(13-5-2)14-10-18-8-9-20(23-3)21(17-18)24-15-11-19-7-6-16-25-19/h6-9,16-17H,4-5,10-15H2,1-3H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074825
PNG
(CHEMBL554037 | [2-(4-Methoxy-6H-benzo[c]chromen-1-...)
Show SMILES CCCN(CCC)CCc1ccc(OC)c2OCc3ccccc3-c12
Show InChI InChI=1S/C22H29NO2/c1-4-13-23(14-5-2)15-12-17-10-11-20(24-3)22-21(17)19-9-7-6-8-18(19)16-25-22/h6-11H,4-5,12-16H2,1-3H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074845
PNG
(1-(2-Dipropylamino-ethyl)-6H-benzo[c]chromen-4-ol;...)
Show SMILES CCCN(CCC)CCc1ccc(O)c2OCc3ccccc3-c12
Show InChI InChI=1S/C21H27NO2/c1-3-12-22(13-4-2)14-11-16-9-10-19(23)21-20(16)18-8-6-5-7-17(18)15-24-21/h5-10,23H,3-4,11-15H2,1-2H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074866
PNG
((2-{3-[2-(4-Fluoro-phenyl)-ethoxy]-4-methoxy-pheny...)
Show SMILES CCCN(CCC)CCc1ccc(OC)c(OCCc2ccc(F)cc2)c1
Show InChI InChI=1S/C23H32FNO2/c1-4-14-25(15-5-2)16-12-20-8-11-22(26-3)23(18-20)27-17-13-19-6-9-21(24)10-7-19/h6-11,18H,4-5,12-17H2,1-3H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074862
PNG
(1-[2-(3-Methoxy-2-phenethyloxy-phenyl)-ethyl]-4-py...)
Show SMILES COc1cccc(CCN2CCN(CC2)c2ccccn2)c1OCCc1ccccc1
Show InChI InChI=1S/C26H31N3O2/c1-30-24-11-7-10-23(26(24)31-21-14-22-8-3-2-4-9-22)13-16-28-17-19-29(20-18-28)25-12-5-6-15-27-25/h2-12,15H,13-14,16-21H2,1H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(RAT)		BDBM50074850
PNG
(CHEMBL11803 | [2-(5-Chloro-2-phenethyloxy-phenyl)-...)
Show SMILES CCCN(CCC)CCc1cc(Cl)ccc1OCCc1ccccc1
Show InChI InChI=1S/C22H30ClNO/c1-3-14-24(15-4-2)16-12-20-18-21(23)10-11-22(20)25-17-13-19-8-6-5-7-9-19/h5-11,18H,3-4,12-17H2,1-2H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]SCH-23390 binding to Dopamine receptor D1 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074835
PNG
(5-(2-Dipropylamino-ethyl)-2-phenethyloxy-phenol; h...)
Show SMILES CCCN(CCC)CCc1ccc(OCCc2ccccc2)c(O)c1
Show InChI InChI=1S/C22H31NO2/c1-3-14-23(15-4-2)16-12-20-10-11-22(21(24)18-20)25-17-13-19-8-6-5-7-9-19/h5-11,18,24H,3-4,12-17H2,1-2H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074833
PNG
(2-(4-Methoxy-3-phenethyloxy-phenyl)-ethylamine; hy...)
Show SMILES COc1ccc(CCN)cc1OCCc1ccccc1
Show InChI InChI=1S/C17H21NO2/c1-19-16-8-7-15(9-11-18)13-17(16)20-12-10-14-5-3-2-4-6-14/h2-8,13H,9-12,18H2,1H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074883
PNG
(CHEMBL262955 | [2-(2-Benzyloxy-3-methoxy-phenyl)-e...)
Show SMILES CCCN(CCC)CCc1cccc(OC)c1OCc1ccccc1
Show InChI InChI=1S/C22H31NO2/c1-4-15-23(16-5-2)17-14-20-12-9-13-21(24-3)22(20)25-18-19-10-7-6-8-11-19/h6-13H,4-5,14-18H2,1-3H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074833
PNG
(2-(4-Methoxy-3-phenethyloxy-phenyl)-ethylamine; hy...)
Show SMILES COc1ccc(CCN)cc1OCCc1ccccc1
Show InChI InChI=1S/C17H21NO2/c1-19-16-8-7-15(9-11-18)13-17(16)20-12-10-14-5-3-2-4-6-14/h2-8,13H,9-12,18H2,1H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074852
PNG
(CHEMBL11598 | [2-(3-Benzyloxy-4-methoxy-phenyl)-et...)
Show SMILES CCCN(CCC)CCc1ccc(OC)c(OCc2ccccc2)c1
Show InChI InChI=1S/C22H31NO2/c1-4-14-23(15-5-2)16-13-19-11-12-21(24-3)22(17-19)25-18-20-9-7-6-8-10-20/h6-12,17H,4-5,13-16,18H2,1-3H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074855
PNG
(1-[2-(4-Methoxy-3-phenethyloxy-phenyl)-ethyl]-pyrr...)
Show SMILES COc1ccc(CCN2CCCC2)cc1OCCc1ccccc1
Show InChI InChI=1S/C21H27NO2/c1-23-20-10-9-19(11-15-22-13-5-6-14-22)17-21(20)24-16-12-18-7-3-2-4-8-18/h2-4,7-10,17H,5-6,11-16H2,1H3
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Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074869
PNG
(4-(2-Dipropylamino-ethyl)-2-phenethyloxy-phenol; h...)
Show SMILES CCCN(CCC)CCc1ccc(O)c(OCCc2ccccc2)c1
Show InChI InChI=1S/C22H31NO2/c1-3-14-23(15-4-2)16-12-20-10-11-21(24)22(18-20)25-17-13-19-8-6-5-7-9-19/h5-11,18,24H,3-4,12-17H2,1-2H3
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n/an/a>1.00E+3n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074879
PNG
(CHEMBL275948 | [3-(3-Methoxy-2-phenethyloxy-phenyl...)
Show SMILES CCCN(CCC)CCCc1cccc(OC)c1OCCc1ccccc1
Show InChI InChI=1S/C24H35NO2/c1-4-17-25(18-5-2)19-10-14-22-13-9-15-23(26-3)24(22)27-20-16-21-11-7-6-8-12-21/h6-9,11-13,15H,4-5,10,14,16-20H2,1-3H3
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n/an/a>1.00E+3n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50074847
PNG
(CHEMBL11590 | [2-(3,5-Dibromo-2-phenethyloxy-pheny...)
Show SMILES CCCN(CCC)CCc1cc(Br)cc(Br)c1OCCc1ccccc1
Show InChI InChI=1S/C22H29Br2NO/c1-3-12-25(13-4-2)14-10-19-16-20(23)17-21(24)22(19)26-15-11-18-8-6-5-7-9-18/h5-9,16-17H,3-4,10-15H2,1-2H3
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n/an/a>1.00E+3n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](-)-sulpiride binding to Dopamine receptor D2 in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50074878
PNG
(4-[2-(4-Methoxy-3-phenethyloxy-phenyl)-ethyl]-morp...)
Show SMILES COc1ccc(CCN2CCOCC2)cc1OCCc1ccccc1
Show InChI InChI=1S/C21H27NO3/c1-23-20-8-7-19(9-11-22-12-15-24-16-13-22)17-21(20)25-14-10-18-5-3-2-4-6-18/h2-8,17H,9-16H2,1H3
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n/an/a>1.00E+3n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membrane

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50074839
PNG
(CHEMBL542047 | [2-(3-Methoxy-2-phenethyloxy-phenyl...)
Show SMILES CCCN(CCC)CCc1cccc(OC)c1OCCc1ccccc1
Show InChI InChI=1S/C23H33NO2/c1-4-16-24(17-5-2)18-14-21-12-9-13-22(25-3)23(21)26-19-15-20-10-7-6-8-11-20/h6-13H,4-5,14-19H2,1-3H3
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n/an/a 3.58E+3n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]hydroxy-2-(di-n-propylamino)-tetralin binding to 5-hydroxytryptamine 1A receptor in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50170660
PNG
(CHEMBL190883 | CHEMBL521582 | N,N-dipropyl-2-[4-me...)
Show SMILES CCCN(CCC)CCc1ccc(OC)c(OCCc2ccccc2)c1
Show InChI InChI=1S/C23H33NO2/c1-4-15-24(16-5-2)17-13-21-11-12-22(25-3)23(19-21)26-18-14-20-9-7-6-8-10-20/h6-12,19H,4-5,13-18H2,1-3H3
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n/an/a 6.46E+3n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]hydroxy-2-(di-n-propylamino)-tetralin binding to 5-hydroxytryptamine 1A receptor in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50074839
PNG
(CHEMBL542047 | [2-(3-Methoxy-2-phenethyloxy-phenyl...)
Show SMILES CCCN(CCC)CCc1cccc(OC)c1OCCc1ccccc1
Show InChI InChI=1S/C23H33NO2/c1-4-16-24(17-5-2)18-14-21-12-9-13-22(25-3)23(21)26-19-15-20-10-7-6-8-11-20/h6-13H,4-5,14-19H2,1-3H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Taisho Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]PCP binding to PCP site of N-methyl-D-aspartate glutamate receptor in rat

J Med Chem 42: 1076-87 (1999)


Article DOI: 10.1021/jm980212v
BindingDB Entry DOI: 10.7270/Q29C6Z4V
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%