BindingDB logo
myBDB logout

PubMed code 10091675

Compile data set for download or QSAR
Found 31 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
UDP-3-O-acyl-N-acetylglucosamine deacetylase


(Escherichia coli)		BDBM50074943
PNG
(2-(3-Benzyloxy-4-methoxy-5-propyl-phenyl)-4,5-dihy...)
Show SMILES CCCc1cc(cc(OCc2ccccc2)c1OC)C1=NC(CO1)C(=O)NO |t:21|
Show InChI InChI=1S/C21H24N2O5/c1-3-7-15-10-16(21-22-17(13-28-21)20(24)23-25)11-18(19(15)26-2)27-12-14-8-5-4-6-9-14/h4-6,8-11,17,25H,3,7,12-13H2,1-2H3,(H,23,24)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 20n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase using direct deacetylase assay (DEACET) in E. coli strain JB 1104

Bioorg Med Chem Lett 9: 313-8 (1999)


BindingDB Entry DOI: 10.7270/Q2CJ8CNN
More data for this
Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase


(Escherichia coli)		BDBM50074960
PNG
((R)-2-(3,4-Dimethoxy-5-propyl-phenyl)-4,5-dihydro-...)
Show SMILES CCCc1cc(cc(OC)c1OC)C1=N[C@H](CO1)C(=O)NO |t:14|
Show InChI InChI=1S/C15H20N2O5/c1-4-5-9-6-10(7-12(20-2)13(9)21-3)15-16-11(8-22-15)14(18)17-19/h6-7,11,19H,4-5,8H2,1-3H3,(H,17,18)/t11-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
PDB
UniChem

Similars
PDB
PubMed
n/an/a 30n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase using direct deacetylase assay (DEACET) in E. coli strain JB 1104

Bioorg Med Chem Lett 9: 313-8 (1999)


BindingDB Entry DOI: 10.7270/Q2CJ8CNN
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
UDP-3-O-acyl-N-acetylglucosamine deacetylase


(Escherichia coli)		BDBM50074941
PNG
((R)-2-(3-Propyl-phenyl)-4,5-dihydro-oxazole-4-carb...)
Show SMILES CCCc1cccc(c1)C1=N[C@H](CO1)C(=O)NO |t:10|
Show InChI InChI=1S/C13H16N2O3/c1-2-4-9-5-3-6-10(7-9)13-14-11(8-18-13)12(16)15-17/h3,5-7,11,17H,2,4,8H2,1H3,(H,15,16)/t11-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 50n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase using direct deacetylase assay (DEACET) in E. coli strain JB 1104

Bioorg Med Chem Lett 9: 313-8 (1999)


BindingDB Entry DOI: 10.7270/Q2CJ8CNN
More data for this
Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase


(Escherichia coli)		BDBM50074941
PNG
((R)-2-(3-Propyl-phenyl)-4,5-dihydro-oxazole-4-carb...)
Show SMILES CCCc1cccc(c1)C1=N[C@H](CO1)C(=O)NO |t:10|
Show InChI InChI=1S/C13H16N2O3/c1-2-4-9-5-3-6-10(7-9)13-14-11(8-18-13)12(16)15-17/h3,5-7,11,17H,2,4,8H2,1H3,(H,15,16)/t11-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 50n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase using coupled radiochemical assay (WAVE) in E. coli strain JB 1104

Bioorg Med Chem Lett 9: 313-8 (1999)


BindingDB Entry DOI: 10.7270/Q2CJ8CNN
More data for this
Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase


(Escherichia coli)		BDBM50074944
PNG
(2-(3,4-Dimethoxy-5-propyl-phenyl)-4,5-dihydro-oxaz...)
Show SMILES CCCc1cc(cc(OC)c1OC)C1=NC(CO1)C(=O)NO |t:14|
Show InChI InChI=1S/C15H20N2O5/c1-4-5-9-6-10(7-12(20-2)13(9)21-3)15-16-11(8-22-15)14(18)17-19/h6-7,11,19H,4-5,8H2,1-3H3,(H,17,18)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
PDB
UniChem

Similars
PDB
PubMed
n/an/a 50n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase using direct deacetylase assay (DEACET) in E. coli strain JB 1104

Bioorg Med Chem Lett 9: 313-8 (1999)


BindingDB Entry DOI: 10.7270/Q2CJ8CNN
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
UDP-3-O-acyl-N-acetylglucosamine deacetylase


(Escherichia coli)		BDBM50074949
PNG
((R)-2-(4-Propyl-phenyl)-4,5-dihydro-oxazole-4-carb...)
Show SMILES CCCc1ccc(cc1)C1=N[C@H](CO1)C(=O)NO |t:10|
Show InChI InChI=1S/C13H16N2O3/c1-2-3-9-4-6-10(7-5-9)13-14-11(8-18-13)12(16)15-17/h4-7,11,17H,2-3,8H2,1H3,(H,15,16)/t11-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 100n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase using coupled radiochemical assay (WAVE) in E. coli strain JB 1104

Bioorg Med Chem Lett 9: 313-8 (1999)


BindingDB Entry DOI: 10.7270/Q2CJ8CNN
More data for this
Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase


(Escherichia coli)		BDBM50074940
PNG
(2-(3-Hydroxy-4-methoxy-5-propyl-phenyl)-4,5-dihydr...)
Show SMILES CCCc1cc(cc(O)c1OC)C1=NC(CO1)C(=O)NO |t:13|
Show InChI InChI=1S/C14H18N2O5/c1-3-4-8-5-9(6-11(17)12(8)20-2)14-15-10(7-21-14)13(18)16-19/h5-6,10,17,19H,3-4,7H2,1-2H3,(H,16,18)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 100n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase using direct deacetylase assay (DEACET) in E. coli strain JB 1104

Bioorg Med Chem Lett 9: 313-8 (1999)


BindingDB Entry DOI: 10.7270/Q2CJ8CNN
More data for this
Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase


(Escherichia coli)		BDBM50074951
PNG
((R)-2-(4-Ethyl-phenyl)-4,5-dihydro-oxazole-4-carbo...)
Show SMILES CCc1ccc(cc1)C1=N[C@H](CO1)C(=O)NO |t:9|
Show InChI InChI=1S/C12H14N2O3/c1-2-8-3-5-9(6-4-8)12-13-10(7-17-12)11(15)14-16/h3-6,10,16H,2,7H2,1H3,(H,14,15)/t10-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 200n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase using coupled radiochemical assay (WAVE) in E. coli strain JB 1104

Bioorg Med Chem Lett 9: 313-8 (1999)


BindingDB Entry DOI: 10.7270/Q2CJ8CNN
More data for this
Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase


(Escherichia coli)		BDBM50074957
PNG
(2-(4-Methoxy-3-propyl-phenyl)-4,5-dihydro-oxazole-...)
Show SMILES CCCc1cc(ccc1OC)C1=NC(CO1)C(=O)NO |t:12|
Show InChI InChI=1S/C14H18N2O4/c1-3-4-9-7-10(5-6-12(9)19-2)14-15-11(8-20-14)13(17)16-18/h5-7,11,18H,3-4,8H2,1-2H3,(H,16,17)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 300n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase using direct deacetylase assay (DEACET) in E. coli strain JB 1104

Bioorg Med Chem Lett 9: 313-8 (1999)


BindingDB Entry DOI: 10.7270/Q2CJ8CNN
More data for this
Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase


(Escherichia coli)		BDBM50074956
PNG
((R)-2-(3,4,5-Trimethoxy-phenyl)-4,5-dihydro-oxazol...)
Show SMILES COc1cc(cc(OC)c1OC)C1=N[C@H](CO1)C(=O)NO |t:13|
Show InChI InChI=1S/C13H16N2O6/c1-18-9-4-7(5-10(19-2)11(9)20-3)13-14-8(6-21-13)12(16)15-17/h4-5,8,17H,6H2,1-3H3,(H,15,16)/t8-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 300n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase using direct deacetylase assay (DEACET) in E. coli strain JB 1104

Bioorg Med Chem Lett 9: 313-8 (1999)


BindingDB Entry DOI: 10.7270/Q2CJ8CNN
More data for this
Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase


(Escherichia coli)		BDBM50074938
PNG
((R)-2-(4-Methoxy-phenyl)-4,5-dihydro-oxazole-4-car...)
Show SMILES COc1ccc(cc1)C1=N[C@H](CO1)C(=O)NO |t:9|
Show InChI InChI=1S/C11H12N2O4/c1-16-8-4-2-7(3-5-8)11-12-9(6-17-11)10(14)13-15/h2-5,9,15H,6H2,1H3,(H,13,14)/t9-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 300n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase using direct deacetylase assay (DEACET) in E. coli strain JB 1104

Bioorg Med Chem Lett 9: 313-8 (1999)


BindingDB Entry DOI: 10.7270/Q2CJ8CNN
More data for this
Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase


(Escherichia coli)		BDBM50074951
PNG
((R)-2-(4-Ethyl-phenyl)-4,5-dihydro-oxazole-4-carbo...)
Show SMILES CCc1ccc(cc1)C1=N[C@H](CO1)C(=O)NO |t:9|
Show InChI InChI=1S/C12H14N2O3/c1-2-8-3-5-9(6-4-8)12-13-10(7-17-12)11(15)14-16/h3-6,10,16H,2,7H2,1H3,(H,14,15)/t10-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 600n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase using direct deacetylase assay (DEACET) in E. coli strain JB 1104

Bioorg Med Chem Lett 9: 313-8 (1999)


BindingDB Entry DOI: 10.7270/Q2CJ8CNN
More data for this
Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase


(Escherichia coli)		BDBM50074947
PNG
(2-m-Tolyl-4,5-dihydro-oxazole-4-carboxylic acid hy...)
Show SMILES Cc1cccc(c1)C1=NC(CO1)C(=O)NO |t:8|
Show InChI InChI=1S/C11H12N2O3/c1-7-3-2-4-8(5-7)11-12-9(6-16-11)10(14)13-15/h2-5,9,15H,6H2,1H3,(H,13,14)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 1.10E+3n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase using coupled radiochemical assay (WAVE) in E. coli strain JB 1104

Bioorg Med Chem Lett 9: 313-8 (1999)


BindingDB Entry DOI: 10.7270/Q2CJ8CNN
More data for this
Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase


(Escherichia coli)		BDBM50074938
PNG
((R)-2-(4-Methoxy-phenyl)-4,5-dihydro-oxazole-4-car...)
Show SMILES COc1ccc(cc1)C1=N[C@H](CO1)C(=O)NO |t:9|
Show InChI InChI=1S/C11H12N2O4/c1-16-8-4-2-7(3-5-8)11-12-9(6-17-11)10(14)13-15/h2-5,9,15H,6H2,1H3,(H,13,14)/t9-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 1.40E+3n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase using direct deacetylase assay (DEACET) in E. coli strain JB 1104

Bioorg Med Chem Lett 9: 313-8 (1999)


BindingDB Entry DOI: 10.7270/Q2CJ8CNN
More data for this
Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase


(Escherichia coli)		BDBM50074946
PNG
(2-(4-Hydroxy-3-methoxy-5-propyl-phenyl)-4,5-dihydr...)
Show SMILES CCCc1cc(cc(OC)c1O)C1=NC(CO1)C(=O)NO |t:13|
Show InChI InChI=1S/C14H18N2O5/c1-3-4-8-5-9(6-11(20-2)12(8)17)14-15-10(7-21-14)13(18)16-19/h5-6,10,17,19H,3-4,7H2,1-2H3,(H,16,18)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 1.40E+3n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase using direct deacetylase assay (DEACET) in E. coli strain JB 1104

Bioorg Med Chem Lett 9: 313-8 (1999)


BindingDB Entry DOI: 10.7270/Q2CJ8CNN
More data for this
Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase


(Escherichia coli)		BDBM50074958
PNG
((R)-2-Phenyl-4,5-dihydro-oxazole-4-carboxylic acid...)
Show SMILES ONC(=O)[C@H]1COC(=N1)c1ccccc1 |c:7|
Show InChI InChI=1S/C10H10N2O3/c13-9(12-14)8-6-15-10(11-8)7-4-2-1-3-5-7/h1-5,8,14H,6H2,(H,12,13)/t8-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase using coupled radiochemical assay (WAVE) in E. coli strain JB 1104

Bioorg Med Chem Lett 9: 313-8 (1999)


BindingDB Entry DOI: 10.7270/Q2CJ8CNN
More data for this
Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase


(Escherichia coli)		BDBM50074958
PNG
((R)-2-Phenyl-4,5-dihydro-oxazole-4-carboxylic acid...)
Show SMILES ONC(=O)[C@H]1COC(=N1)c1ccccc1 |c:7|
Show InChI InChI=1S/C10H10N2O3/c13-9(12-14)8-6-15-10(11-8)7-4-2-1-3-5-7/h1-5,8,14H,6H2,(H,12,13)/t8-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase using coupled radiochemical assay (WAVE) in E. coli strain JB 1104

Bioorg Med Chem Lett 9: 313-8 (1999)


BindingDB Entry DOI: 10.7270/Q2CJ8CNN
More data for this
Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase


(Escherichia coli)		BDBM50074961
PNG
(2-p-Tolyl-4,5-dihydro-oxazole-4-carboxylic acid hy...)
Show SMILES Cc1ccc(cc1)C1=NC(CO1)C(=O)NO |t:8|
Show InChI InChI=1S/C11H12N2O3/c1-7-2-4-8(5-3-7)11-12-9(6-16-11)10(14)13-15/h2-5,9,15H,6H2,1H3,(H,13,14)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 1.70E+3n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase using coupled radiochemical assay (WAVE) in E. coli strain JB 1104

Bioorg Med Chem Lett 9: 313-8 (1999)


BindingDB Entry DOI: 10.7270/Q2CJ8CNN
More data for this
Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase


(Escherichia coli)		BDBM50074963
PNG
(2-o-Tolyl-4,5-dihydro-oxazole-4-carboxylic acid hy...)
Show SMILES Cc1ccccc1C1=NC(CO1)C(=O)NO |t:8|
Show InChI InChI=1S/C11H12N2O3/c1-7-4-2-3-5-8(7)11-12-9(6-16-11)10(14)13-15/h2-5,9,15H,6H2,1H3,(H,13,14)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 2.60E+3n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase using coupled radiochemical assay (WAVE) in E. coli strain JB 1104

Bioorg Med Chem Lett 9: 313-8 (1999)


BindingDB Entry DOI: 10.7270/Q2CJ8CNN
More data for this
Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase


(Escherichia coli)		BDBM50074939
PNG
(2-Phenyl-4,5-dihydro-oxazole-4-carboxylic acid hyd...)
Show SMILES ONC(=O)C1COC(=N1)c1ccccc1 |c:7|
Show InChI InChI=1S/C10H10N2O3/c13-9(12-14)8-6-15-10(11-8)7-4-2-1-3-5-7/h1-5,8,14H,6H2,(H,12,13)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 3.00E+3n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase using coupled radiochemical assay (WAVE) in E. coli strain JB 1104

Bioorg Med Chem Lett 9: 313-8 (1999)


BindingDB Entry DOI: 10.7270/Q2CJ8CNN
More data for this
Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase


(Escherichia coli)		BDBM50074939
PNG
(2-Phenyl-4,5-dihydro-oxazole-4-carboxylic acid hyd...)
Show SMILES ONC(=O)C1COC(=N1)c1ccccc1 |c:7|
Show InChI InChI=1S/C10H10N2O3/c13-9(12-14)8-6-15-10(11-8)7-4-2-1-3-5-7/h1-5,8,14H,6H2,(H,12,13)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 3.00E+3n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase using direct deacetylase assay (DEACET) in E. coli strain JB 1104

Bioorg Med Chem Lett 9: 313-8 (1999)


BindingDB Entry DOI: 10.7270/Q2CJ8CNN
More data for this
Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase


(Escherichia coli)		BDBM50074955
PNG
((R)-2-Furan-2-yl-4,5-dihydro-oxazole-4-carboxylic ...)
Show SMILES ONC(=O)[C@H]1COC(=N1)c1ccco1 |c:7|
Show InChI InChI=1S/C8H8N2O4/c11-7(10-12)5-4-14-8(9-5)6-2-1-3-13-6/h1-3,5,12H,4H2,(H,10,11)/t5-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 9.00E+3n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase using coupled radiochemical assay (WAVE) in E. coli strain JB 1104

Bioorg Med Chem Lett 9: 313-8 (1999)


BindingDB Entry DOI: 10.7270/Q2CJ8CNN
More data for this
Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase


(Escherichia coli)		BDBM50074942
PNG
(2-(2-Chloro-phenyl)-4,5-dihydro-oxazole-4-carboxyl...)
Show SMILES ONC(=O)C1COC(=N1)c1ccccc1Cl |c:7|
Show InChI InChI=1S/C10H9ClN2O3/c11-7-4-2-1-3-6(7)10-12-8(5-16-10)9(14)13-15/h1-4,8,15H,5H2,(H,13,14)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 3.00E+4n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase using direct deacetylase assay (DEACET) in E. coli strain JB 1104

Bioorg Med Chem Lett 9: 313-8 (1999)


BindingDB Entry DOI: 10.7270/Q2CJ8CNN
More data for this
Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase


(Escherichia coli)		BDBM50074950
PNG
(2-Pyridin-4-yl-4,5-dihydro-oxazole-4-carboxylic ac...)
Show SMILES ONC(=O)C1COC(=N1)c1ccncc1 |c:7|
Show InChI InChI=1S/C9H9N3O3/c13-8(12-14)7-5-15-9(11-7)6-1-3-10-4-2-6/h1-4,7,14H,5H2,(H,12,13)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 1.00E+5n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase using direct deacetylase assay (DEACET) in E. coli strain JB 1104

Bioorg Med Chem Lett 9: 313-8 (1999)


BindingDB Entry DOI: 10.7270/Q2CJ8CNN
More data for this
Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase


(Escherichia coli)		BDBM50074948
PNG
(2-Pyridin-3-yl-4,5-dihydro-oxazole-4-carboxylic ac...)
Show SMILES ONC(=O)C1COC(=N1)c1cccnc1 |c:7|
Show InChI InChI=1S/C9H9N3O3/c13-8(12-14)7-5-15-9(11-7)6-2-1-3-10-4-6/h1-4,7,14H,5H2,(H,12,13)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 1.00E+5n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase using direct deacetylase assay (DEACET) in E. coli strain JB 1104

Bioorg Med Chem Lett 9: 313-8 (1999)


BindingDB Entry DOI: 10.7270/Q2CJ8CNN
More data for this
Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase


(Escherichia coli)		BDBM50074953
PNG
(2-(2,6-Dichloro-phenyl)-4,5-dihydro-oxazole-4-carb...)
Show SMILES ONC(=O)C1COC(=N1)c1c(Cl)cccc1Cl |c:7|
Show InChI InChI=1S/C10H8Cl2N2O3/c11-5-2-1-3-6(12)8(5)10-13-7(4-17-10)9(15)14-16/h1-3,7,16H,4H2,(H,14,15)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase using direct deacetylase assay (DEACET) in E. coli strain JB 1104

Bioorg Med Chem Lett 9: 313-8 (1999)


BindingDB Entry DOI: 10.7270/Q2CJ8CNN
More data for this
Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase


(Escherichia coli)		BDBM50074962
PNG
((S)-2-Phenyl-4,5-dihydro-oxazole-4-carboxylic acid...)
Show SMILES ONC(=O)[C@@H]1COC(=N1)c1ccccc1 |c:7|
Show InChI InChI=1S/C10H10N2O3/c13-9(12-14)8-6-15-10(11-8)7-4-2-1-3-5-7/h1-5,8,14H,6H2,(H,12,13)/t8-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 3.60E+5n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase using coupled radiochemical assay (WAVE) in E. coli strain JB 1104

Bioorg Med Chem Lett 9: 313-8 (1999)


BindingDB Entry DOI: 10.7270/Q2CJ8CNN
More data for this
Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase


(Escherichia coli)		BDBM50074952
PNG
((R)-2-Phenyl-4,5-dihydro-oxazole-4-carboxylic acid...)
Show SMILES CN(O)C(=O)[C@H]1COC(=N1)c1ccccc1 |c:8|
Show InChI InChI=1S/C11H12N2O3/c1-13(15)11(14)9-7-16-10(12-9)8-5-3-2-4-6-8/h2-6,9,15H,7H2,1H3/t9-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a>4.00E+5n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase using coupled radiochemical assay (WAVE) in E. coli strain JB 1104

Bioorg Med Chem Lett 9: 313-8 (1999)


BindingDB Entry DOI: 10.7270/Q2CJ8CNN
More data for this
Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase


(Escherichia coli)		BDBM50074945
PNG
((R)-2-Phenyl-4,5-dihydro-oxazole-4-carboxylic acid...)
Show SMILES CN(OCc1ccccc1)C(=O)[C@H]1COC(=N1)c1ccccc1 |c:16|
Show InChI InChI=1S/C18H18N2O3/c1-20(23-12-14-8-4-2-5-9-14)18(21)16-13-22-17(19-16)15-10-6-3-7-11-15/h2-11,16H,12-13H2,1H3/t16-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a>4.00E+5n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase using coupled radiochemical assay (WAVE) in E. coli strain JB 1104

Bioorg Med Chem Lett 9: 313-8 (1999)


BindingDB Entry DOI: 10.7270/Q2CJ8CNN
More data for this
Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase


(Escherichia coli)		BDBM50074954
PNG
(2-Phenyl-4,5-dihydro-oxazole-4-carboxylic acid | C...)
Show SMILES OC(=O)C1COC(=N1)c1ccccc1 |c:6|
Show InChI InChI=1S/C10H9NO3/c12-10(13)8-6-14-9(11-8)7-4-2-1-3-5-7/h1-5,8H,6H2,(H,12,13)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
n/an/a>4.00E+5n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase using coupled radiochemical assay (WAVE) in E. coli strain JB 1104

Bioorg Med Chem Lett 9: 313-8 (1999)


BindingDB Entry DOI: 10.7270/Q2CJ8CNN
More data for this
Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase


(Escherichia coli)		BDBM50074959
PNG
(2-Phenyl-4,5-dihydro-oxazole-4-carboxylic acid met...)
Show SMILES COC(=O)C1COC(=N1)c1ccccc1 |c:7|
Show InChI InChI=1S/C11H11NO3/c1-14-11(13)9-7-15-10(12-9)8-5-3-2-4-6-8/h2-6,9H,7H2,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
n/an/a>4.00E+5n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase using coupled radiochemical assay (WAVE) in E. coli strain JB 1104

Bioorg Med Chem Lett 9: 313-8 (1999)


BindingDB Entry DOI: 10.7270/Q2CJ8CNN
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%