BindingDB logo
myBDB logout

PubMed code 10476864

Compile data set for download or QSAR
Found 22 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM8963
PNG
(CHEMBL32823 | Homodimeric Tacrine Analog 3b | N-[7...)
Show SMILES C(CCCNc1c2CCCCc2nc2ccccc12)CCCNc1c2CCCCc2nc2ccccc12
Show InChI InChI=1S/C33H40N4/c1(2-12-22-34-32-24-14-4-8-18-28(24)36-29-19-9-5-15-25(29)32)3-13-23-35-33-26-16-6-10-20-30(26)37-31-21-11-7-17-27(31)33/h4,6,8,10,14,16,18,20H,1-3,5,7,9,11-13,15,17,19,21-23H2,(H,34,36)(H,35,37)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
MMDB
PC cid
PC sid
PDB
UniChem

Similars
PubMed
n/an/a 1.5n/an/an/an/an/an/a



Hong Kong University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibitory potency against acetylcholinesterase (AChE) of rat cortex homogenate with ethopropazine as BChE inhibitor

Bioorg Med Chem Lett 9: 2335-8 (1999)


BindingDB Entry DOI: 10.7270/Q2PK0GPF
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50080157
PNG
((RS)-tacrine(10)-hupyridone | 5-[10-(1,2,3,4-Tetra...)
Show SMILES O=c1ccc2C(CCCc2[nH]1)NCCCCCCCCCCNc1c2CCCCc2nc2ccccc12
Show InChI InChI=1S/C32H44N4O/c37-31-21-20-24-27(18-13-19-28(24)36-31)33-22-11-5-3-1-2-4-6-12-23-34-32-25-14-7-9-16-29(25)35-30-17-10-8-15-26(30)32/h7,9,14,16,20-21,27,33H,1-6,8,10-13,15,17-19,22-23H2,(H,34,35)(H,36,37)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
PDB
UniChem

Similars
PubMed
n/an/a 8.80n/an/an/an/an/an/a



Hong Kong University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibitory potency against acetylcholinesterase (AChE) of rat cortex homogenate with ethopropazine as BChE inhibitor

Bioorg Med Chem Lett 9: 2335-8 (1999)


BindingDB Entry DOI: 10.7270/Q2PK0GPF
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50080160
PNG
(5-[8-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-octyla...)
Show SMILES O=c1ccc2C(CCCc2[nH]1)NCCCCCCCCNc1c2CCCCc2nc2ccccc12
Show InChI InChI=1S/C30H40N4O/c35-29-19-18-22-25(16-11-17-26(22)34-29)31-20-9-3-1-2-4-10-21-32-30-23-12-5-7-14-27(23)33-28-15-8-6-13-24(28)30/h5,7,12,14,18-19,25,31H,1-4,6,8-11,13,15-17,20-21H2,(H,32,33)(H,34,35)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
n/an/a 26n/an/an/an/an/an/a



Hong Kong University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibitory potency against acetylcholinesterase (AChE) of rat cortex homogenate with ethopropazine as BChE inhibitor

Bioorg Med Chem Lett 9: 2335-8 (1999)


BindingDB Entry DOI: 10.7270/Q2PK0GPF
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50080162
PNG
(5-[9-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-nonyla...)
Show SMILES O=c1ccc2C(CCCc2[nH]1)NCCCCCCCCCNc1c2CCCCc2nc2ccccc12
Show InChI InChI=1S/C31H42N4O/c36-30-20-19-23-26(17-12-18-27(23)35-30)32-21-10-4-2-1-3-5-11-22-33-31-24-13-6-8-15-28(24)34-29-16-9-7-14-25(29)31/h6,8,13,15,19-20,26,32H,1-5,7,9-12,14,16-18,21-22H2,(H,33,34)(H,35,36)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 36n/an/an/an/an/an/a



Hong Kong University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibitory potency against acetylcholinesterase (AChE) of rat cortex homogenate with ethopropazine as BChE inhibitor

Bioorg Med Chem Lett 9: 2335-8 (1999)


BindingDB Entry DOI: 10.7270/Q2PK0GPF
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50366608
PNG
(CHEMBL1202834)
Show SMILES O=c1ccc2C(CCCc2[nH]1)NCCCCCCNc1c2CCCCc2nc2ccccc12
Show InChI InChI=1S/C28H36N4O/c33-27-17-16-20-23(14-9-15-24(20)32-27)29-18-7-1-2-8-19-30-28-21-10-3-5-12-25(21)31-26-13-6-4-11-22(26)28/h3,5,10,12,16-17,23,29H,1-2,4,6-9,11,13-15,18-19H2,(H,30,31)(H,32,33)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 37n/an/an/an/an/an/a



Hong Kong University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibitory potency against acetylcholinesterase (AChE) of rat cortex homogenate with ethopropazine as BChE inhibitor

Bioorg Med Chem Lett 9: 2335-8 (1999)


BindingDB Entry DOI: 10.7270/Q2PK0GPF
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50366606
PNG
(CHEMBL1202835)
Show SMILES O=c1ccc2C(CCCc2[nH]1)NCCCCNc1c2CCCCc2nc2ccccc12
Show InChI InChI=1S/C26H32N4O/c31-25-15-14-18-21(12-7-13-22(18)30-25)27-16-5-6-17-28-26-19-8-1-3-10-23(19)29-24-11-4-2-9-20(24)26/h1,3,8,10,14-15,21,27H,2,4-7,9,11-13,16-17H2,(H,28,29)(H,30,31)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 43n/an/an/an/an/an/a



Hong Kong University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibitory potency against acetylcholinesterase (AChE) of rat cortex homogenate with ethopropazine as BChE inhibitor

Bioorg Med Chem Lett 9: 2335-8 (1999)


BindingDB Entry DOI: 10.7270/Q2PK0GPF
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50366605
PNG
(CHEMBL1202836)
Show SMILES O=c1ccc2C(CCCc2[nH]1)NCCCCCCCNc1c2CCCCc2nc2ccccc12
Show InChI InChI=1S/C29H38N4O/c34-28-18-17-21-24(15-10-16-25(21)33-28)30-19-8-2-1-3-9-20-31-29-22-11-4-6-13-26(22)32-27-14-7-5-12-23(27)29/h4,6,11,13,17-18,24,30H,1-3,5,7-10,12,14-16,19-20H2,(H,31,32)(H,33,34)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 53n/an/an/an/an/an/a



Hong Kong University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibitory potency against acetylcholinesterase (AChE) of rat cortex homogenate with ethopropazine as BChE inhibitor

Bioorg Med Chem Lett 9: 2335-8 (1999)


BindingDB Entry DOI: 10.7270/Q2PK0GPF
More data for this
Ligand-Target Pair
Carboxylic ester hydrolase


(Rattus norvegicus (rat))		BDBM50080157
PNG
((RS)-tacrine(10)-hupyridone | 5-[10-(1,2,3,4-Tetra...)
Show SMILES O=c1ccc2C(CCCc2[nH]1)NCCCCCCCCCCNc1c2CCCCc2nc2ccccc12
Show InChI InChI=1S/C32H44N4O/c37-31-21-20-24-27(18-13-19-28(24)36-31)33-22-11-5-3-1-2-4-6-12-23-34-32-25-14-7-9-16-29(25)35-30-17-10-8-15-26(30)32/h7,9,14,16,20-21,27,33H,1-6,8,10-13,15,17-19,22-23H2,(H,34,35)(H,36,37)
Reactome pathway
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
PDB
UniChem

Similars
PubMed
n/an/a 82n/an/an/an/an/an/a



Hong Kong University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibitory potency against rat serum Butyrylcholinesterase with BW284c51 as AChE inhibitor

Bioorg Med Chem Lett 9: 2335-8 (1999)


BindingDB Entry DOI: 10.7270/Q2PK0GPF
More data for this
Ligand-Target Pair
Carboxylic ester hydrolase


(Rattus norvegicus (rat))		BDBM8961
PNG
(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Show SMILES Nc1c2CCCCc2nc2ccccc12
Show InChI InChI=1S/C13H14N2/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13/h1,3,5,7H,2,4,6,8H2,(H2,14,15)
Reactome pathway
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents

Similars
PubMed
n/an/a 92n/an/an/an/an/an/a



Hong Kong University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibitory potency against rat serum Butyrylcholinesterase with BW284c51 as AChE inhibitor

Bioorg Med Chem Lett 9: 2335-8 (1999)


BindingDB Entry DOI: 10.7270/Q2PK0GPF
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50080164
PNG
(5-[12-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-dodec...)
Show SMILES O=c1ccc2C(CCCc2[nH]1)NCCCCCCCCCCCCNc1c2CCCCc2nc2ccccc12
Show InChI InChI=1S/C34H48N4O/c39-33-23-22-26-29(20-15-21-30(26)38-33)35-24-13-7-5-3-1-2-4-6-8-14-25-36-34-27-16-9-11-18-31(27)37-32-19-12-10-17-28(32)34/h9,11,16,18,22-23,29,35H,1-8,10,12-15,17,19-21,24-25H2,(H,36,37)(H,38,39)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 112n/an/an/an/an/an/a



Hong Kong University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibitory potency against acetylcholinesterase (AChE) of rat cortex homogenate with ethopropazine as BChE inhibitor

Bioorg Med Chem Lett 9: 2335-8 (1999)


BindingDB Entry DOI: 10.7270/Q2PK0GPF
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50342601
PNG
(CHEMBL1255901 | Huperzine A)
Show SMILES C\C=C1/[C@@H]2Cc3[nH]c(=O)ccc3[C@]1(N)CC(C)=C2 |r,c:18,TLB:1:2:11.5.4:17.14.15|
Show InChI InChI=1S/C15H18N2O/c1-3-11-10-6-9(2)8-15(11,16)12-4-5-14(18)17-13(12)7-10/h3-6,10H,7-8,16H2,1-2H3,(H,17,18)/b11-3+/t10-,15-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 114n/an/an/an/an/an/a



Hong Kong University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibitory potency against acetylcholinesterase (AChE) of rat cortex homogenate with ethopropazine as BChE inhibitor

Bioorg Med Chem Lett 9: 2335-8 (1999)


BindingDB Entry DOI: 10.7270/Q2PK0GPF
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50366607
PNG
(CHEMBL1202837)
Show SMILES O=c1ccc2C(CCCc2[nH]1)NCCCCCNc1c2CCCCc2nc2ccccc12
Show InChI InChI=1S/C27H34N4O/c32-26-16-15-19-22(13-8-14-23(19)31-26)28-17-6-1-7-18-29-27-20-9-2-4-11-24(20)30-25-12-5-3-10-21(25)27/h2,4,9,11,15-16,22,28H,1,3,5-8,10,12-14,17-18H2,(H,29,30)(H,31,32)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 122n/an/an/an/an/an/a



Hong Kong University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibitory potency against acetylcholinesterase (AChE) of rat cortex homogenate with ethopropazine as BChE inhibitor

Bioorg Med Chem Lett 9: 2335-8 (1999)


BindingDB Entry DOI: 10.7270/Q2PK0GPF
More data for this
Ligand-Target Pair
Carboxylic ester hydrolase


(Rattus norvegicus (rat))		BDBM8963
PNG
(CHEMBL32823 | Homodimeric Tacrine Analog 3b | N-[7...)
Show SMILES C(CCCNc1c2CCCCc2nc2ccccc12)CCCNc1c2CCCCc2nc2ccccc12
Show InChI InChI=1S/C33H40N4/c1(2-12-22-34-32-24-14-4-8-18-28(24)36-29-19-9-5-15-25(29)32)3-13-23-35-33-26-16-6-10-20-30(26)37-31-21-11-7-17-27(31)33/h4,6,8,10,14,16,18,20H,1-3,5,7,9,11-13,15,17,19,21-23H2,(H,34,36)(H,35,37)
Reactome pathway
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
MMDB
PC cid
PC sid
PDB
UniChem

Similars
PubMed
n/an/a 149n/an/an/an/an/an/a



Hong Kong University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibitory potency against rat serum Butyrylcholinesterase with BW284c51 as AChE inhibitor

Bioorg Med Chem Lett 9: 2335-8 (1999)


BindingDB Entry DOI: 10.7270/Q2PK0GPF
More data for this
Ligand-Target Pair
Carboxylic ester hydrolase


(Rattus norvegicus (rat))		BDBM50080162
PNG
(5-[9-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-nonyla...)
Show SMILES O=c1ccc2C(CCCc2[nH]1)NCCCCCCCCCNc1c2CCCCc2nc2ccccc12
Show InChI InChI=1S/C31H42N4O/c36-30-20-19-23-26(17-12-18-27(23)35-30)32-21-10-4-2-1-3-5-11-22-33-31-24-13-6-8-15-28(24)34-29-16-9-7-14-25(29)31/h6,8,13,15,19-20,26,32H,1-5,7,9-12,14,16-18,21-22H2,(H,33,34)(H,35,36)
Reactome pathway
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 150n/an/an/an/an/an/a



Hong Kong University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibitory potency against rat serum Butyrylcholinesterase with BW284c51 as AChE inhibitor

Bioorg Med Chem Lett 9: 2335-8 (1999)


BindingDB Entry DOI: 10.7270/Q2PK0GPF
More data for this
Ligand-Target Pair
Carboxylic ester hydrolase


(Rattus norvegicus (rat))		BDBM50080160
PNG
(5-[8-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-octyla...)
Show SMILES O=c1ccc2C(CCCc2[nH]1)NCCCCCCCCNc1c2CCCCc2nc2ccccc12
Show InChI InChI=1S/C30H40N4O/c35-29-19-18-22-25(16-11-17-26(22)34-29)31-20-9-3-1-2-4-10-21-32-30-23-12-5-7-14-27(23)33-28-15-8-6-13-24(28)30/h5,7,12,14,18-19,25,31H,1-4,6,8-11,13,15-17,20-21H2,(H,32,33)(H,34,35)
Reactome pathway
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
n/an/a 166n/an/an/an/an/an/a



Hong Kong University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibitory potency against rat serum Butyrylcholinesterase with BW284c51 as AChE inhibitor

Bioorg Med Chem Lett 9: 2335-8 (1999)


BindingDB Entry DOI: 10.7270/Q2PK0GPF
More data for this
Ligand-Target Pair
Carboxylic ester hydrolase


(Rattus norvegicus (rat))		BDBM50366607
PNG
(CHEMBL1202837)
Show SMILES O=c1ccc2C(CCCc2[nH]1)NCCCCCNc1c2CCCCc2nc2ccccc12
Show InChI InChI=1S/C27H34N4O/c32-26-16-15-19-22(13-8-14-23(19)31-26)28-17-6-1-7-18-29-27-20-9-2-4-11-24(20)30-25-12-5-3-10-21(25)27/h2,4,9,11,15-16,22,28H,1,3,5-8,10,12-14,17-18H2,(H,29,30)(H,31,32)
Reactome pathway
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 220n/an/an/an/an/an/a



Hong Kong University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibitory potency against rat serum Butyrylcholinesterase with BW284c51 as AChE inhibitor

Bioorg Med Chem Lett 9: 2335-8 (1999)


BindingDB Entry DOI: 10.7270/Q2PK0GPF
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM8961
PNG
(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Show SMILES Nc1c2CCCCc2nc2ccccc12
Show InChI InChI=1S/C13H14N2/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13/h1,3,5,7H,2,4,6,8H2,(H2,14,15)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents

Similars
PDB
PubMed
n/an/a 223n/an/an/an/an/an/a



Hong Kong University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibitory potency against acetylcholinesterase (AChE) of rat cortex homogenate with ethopropazine as BChE inhibitor

Bioorg Med Chem Lett 9: 2335-8 (1999)


BindingDB Entry DOI: 10.7270/Q2PK0GPF
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Carboxylic ester hydrolase


(Rattus norvegicus (rat))		BDBM50366608
PNG
(CHEMBL1202834)
Show SMILES O=c1ccc2C(CCCc2[nH]1)NCCCCCCNc1c2CCCCc2nc2ccccc12
Show InChI InChI=1S/C28H36N4O/c33-27-17-16-20-23(14-9-15-24(20)32-27)29-18-7-1-2-8-19-30-28-21-10-3-5-12-25(21)31-26-13-6-4-11-22(26)28/h3,5,10,12,16-17,23,29H,1-2,4,6-9,11,13-15,18-19H2,(H,30,31)(H,32,33)
Reactome pathway
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 223n/an/an/an/an/an/a



Hong Kong University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibitory potency against rat serum Butyrylcholinesterase with BW284c51 as AChE inhibitor

Bioorg Med Chem Lett 9: 2335-8 (1999)


BindingDB Entry DOI: 10.7270/Q2PK0GPF
More data for this
Ligand-Target Pair
Carboxylic ester hydrolase


(Rattus norvegicus (rat))		BDBM50366606
PNG
(CHEMBL1202835)
Show SMILES O=c1ccc2C(CCCc2[nH]1)NCCCCNc1c2CCCCc2nc2ccccc12
Show InChI InChI=1S/C26H32N4O/c31-25-15-14-18-21(12-7-13-22(18)30-25)27-16-5-6-17-28-26-19-8-1-3-10-23(19)29-24-11-4-2-9-20(24)26/h1,3,8,10,14-15,21,27H,2,4-7,9,11-13,16-17H2,(H,28,29)(H,30,31)
Reactome pathway
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 228n/an/an/an/an/an/a



Hong Kong University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibitory potency against rat serum Butyrylcholinesterase with BW284c51 as AChE inhibitor

Bioorg Med Chem Lett 9: 2335-8 (1999)


BindingDB Entry DOI: 10.7270/Q2PK0GPF
More data for this
Ligand-Target Pair
Carboxylic ester hydrolase


(Rattus norvegicus (rat))		BDBM50366605
PNG
(CHEMBL1202836)
Show SMILES O=c1ccc2C(CCCc2[nH]1)NCCCCCCCNc1c2CCCCc2nc2ccccc12
Show InChI InChI=1S/C29H38N4O/c34-28-18-17-21-24(15-10-16-25(21)33-28)30-19-8-2-1-3-9-20-31-29-22-11-4-6-13-26(22)32-27-14-7-5-12-23(27)29/h4,6,11,13,17-18,24,30H,1-3,5,7-10,12,14-16,19-20H2,(H,31,32)(H,33,34)
Reactome pathway
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 233n/an/an/an/an/an/a



Hong Kong University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibitory potency against rat serum Butyrylcholinesterase with BW284c51 as AChE inhibitor

Bioorg Med Chem Lett 9: 2335-8 (1999)


BindingDB Entry DOI: 10.7270/Q2PK0GPF
More data for this
Ligand-Target Pair
Carboxylic ester hydrolase


(Rattus norvegicus (rat))		BDBM50080164
PNG
(5-[12-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-dodec...)
Show SMILES O=c1ccc2C(CCCc2[nH]1)NCCCCCCCCCCCCNc1c2CCCCc2nc2ccccc12
Show InChI InChI=1S/C34H48N4O/c39-33-23-22-26-29(20-15-21-30(26)38-33)35-24-13-7-5-3-1-2-4-6-8-14-25-36-34-27-16-9-11-18-31(27)37-32-19-12-10-17-28(32)34/h9,11,16,18,22-23,29,35H,1-8,10,12-15,17,19-21,24-25H2,(H,36,37)(H,38,39)
Reactome pathway
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 434n/an/an/an/an/an/a



Hong Kong University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibitory potency against rat serum Butyrylcholinesterase with BW284c51 as AChE inhibitor

Bioorg Med Chem Lett 9: 2335-8 (1999)


BindingDB Entry DOI: 10.7270/Q2PK0GPF
More data for this
Ligand-Target Pair
Carboxylic ester hydrolase


(Rattus norvegicus (rat))		BDBM50342601
PNG
(CHEMBL1255901 | Huperzine A)
Show SMILES C\C=C1/[C@@H]2Cc3[nH]c(=O)ccc3[C@]1(N)CC(C)=C2 |r,c:18,TLB:1:2:11.5.4:17.14.15|
Show InChI InChI=1S/C15H18N2O/c1-3-11-10-6-9(2)8-15(11,16)12-4-5-14(18)17-13(12)7-10/h3-6,10H,7-8,16H2,1-2H3,(H,17,18)/b11-3+/t10-,15-/m0/s1
Reactome pathway
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 1.35E+5n/an/an/an/an/an/a



Hong Kong University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibitory potency against rat serum Butyrylcholinesterase with BW284c51 as AChE inhibitor

Bioorg Med Chem Lett 9: 2335-8 (1999)


BindingDB Entry DOI: 10.7270/Q2PK0GPF
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%