Affinity Data by PubMed id=10498220

PubMed code 10498220

Found 22 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50081137 (7-Chloro-3-(3,5-dimethyl-phenyl)-4-[2-(1-methyl-pi...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-Buserelin to GnRH receptor in rat pituitary membranes.				Bioorg Med Chem Lett 9: 2615-20 (1999) BindingDB Entry DOI: 10.7270/Q2TD9WK0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50081146 (3-(3,5-Dimethyl-phenyl)-4-[2-(1-methyl-piperidin-2...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-Buserelin to GnRH receptor in rat pituitary membranes.				Bioorg Med Chem Lett 9: 2615-20 (1999) BindingDB Entry DOI: 10.7270/Q2TD9WK0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50081138 (7-Bromo-3-(3,5-dimethyl-phenyl)-4-[2-(1-methyl-pip...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-Buserelin to GnRH receptor in rat pituitary membranes.				Bioorg Med Chem Lett 9: 2615-20 (1999) BindingDB Entry DOI: 10.7270/Q2TD9WK0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50081133 (7-Chloro-3-(3,5-dimethyl-phenyl)-4-[2-(1-methyl-py...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-Buserelin to GnRH receptor in rat pituitary membranes.				Bioorg Med Chem Lett 9: 2615-20 (1999) BindingDB Entry DOI: 10.7270/Q2TD9WK0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50081142 (7-Chloro-3-(3,5-dimethyl-phenyl)-4-[2-(1-methyl-pi...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-Buserelin to GnRH receptor in rat pituitary membranes.				Bioorg Med Chem Lett 9: 2615-20 (1999) BindingDB Entry DOI: 10.7270/Q2TD9WK0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50081134 (7-Chloro-3-(3,5-dimethyl-phenyl)-4-(1-methyl-azepa...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-Buserelin to GnRH receptor in rat pituitary membranes.				Bioorg Med Chem Lett 9: 2615-20 (1999) BindingDB Entry DOI: 10.7270/Q2TD9WK0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50081135 (7-Chloro-3-(3,5-dimethyl-phenyl)-4-(1-methyl-piper...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-Buserelin to GnRH receptor in rat pituitary membranes.				Bioorg Med Chem Lett 9: 2615-20 (1999) BindingDB Entry DOI: 10.7270/Q2TD9WK0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50081139 (7-Chloro-3-(3,5-dimethyl-phenyl)-4-(piperidin-3-yl...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-Buserelin to GnRH receptor in rat pituitary membranes.				Bioorg Med Chem Lett 9: 2615-20 (1999) BindingDB Entry DOI: 10.7270/Q2TD9WK0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50081127 (7-Chloro-3-(3,5-dimethyl-phenyl)-4-(1-methyl-pyrro...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-Buserelin to GnRH receptor in rat pituitary membranes.				Bioorg Med Chem Lett 9: 2615-20 (1999) BindingDB Entry DOI: 10.7270/Q2TD9WK0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50081143 (7-Chloro-3-(3,5-dimethyl-phenyl)-4-(1-methyl-azepa...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-Buserelin to GnRH receptor in rat pituitary membranes.				Bioorg Med Chem Lett 9: 2615-20 (1999) BindingDB Entry DOI: 10.7270/Q2TD9WK0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50081141 (7-Chloro-3-(3,5-dimethyl-phenyl)-4-(1-methyl-piper...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-Buserelin to GnRH receptor in rat pituitary membranes.				Bioorg Med Chem Lett 9: 2615-20 (1999) BindingDB Entry DOI: 10.7270/Q2TD9WK0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50081129 (3-(3,5-Dimethyl-phenyl)-4-(1-methyl-piperidin-3-yl...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-Buserelin to GnRH receptor in rat pituitary membranes.				Bioorg Med Chem Lett 9: 2615-20 (1999) BindingDB Entry DOI: 10.7270/Q2TD9WK0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50081140 (7-Chloro-3-(3,5-dimethyl-phenyl)-4-(4-methyl-morph...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-Buserelin to GnRH receptor in rat pituitary membranes.				Bioorg Med Chem Lett 9: 2615-20 (1999) BindingDB Entry DOI: 10.7270/Q2TD9WK0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50081144 (3-(3,5-Dimethyl-phenyl)-7-methyl-4-(1-methyl-piper...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-Buserelin to GnRH receptor in rat pituitary membranes.				Bioorg Med Chem Lett 9: 2615-20 (1999) BindingDB Entry DOI: 10.7270/Q2TD9WK0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50081145 (7-Chloro-3-(3,5-dimethyl-phenyl)-4-(1-methyl-piper...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-Buserelin to GnRH receptor in rat pituitary membranes.				Bioorg Med Chem Lett 9: 2615-20 (1999) BindingDB Entry DOI: 10.7270/Q2TD9WK0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50081130 (7-Chloro-4-(1-methyl-piperidin-3-ylmethoxy)-3-phen...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-Buserelin to GnRH receptor in rat pituitary membranes.				Bioorg Med Chem Lett 9: 2615-20 (1999) BindingDB Entry DOI: 10.7270/Q2TD9WK0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50081131 (7-Chloro-4-(3-dimethylamino-2-methyl-propoxy)-3-(3...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-Buserelin to GnRH receptor in rat pituitary membranes.				Bioorg Med Chem Lett 9: 2615-20 (1999) BindingDB Entry DOI: 10.7270/Q2TD9WK0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50081128 (7-Chloro-4-(1-methyl-azepan-3-yloxy)-3-phenyl-1H-q...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-Buserelin to GnRH receptor in rat pituitary membranes.				Bioorg Med Chem Lett 9: 2615-20 (1999) BindingDB Entry DOI: 10.7270/Q2TD9WK0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50081136 (7-Chloro-3-(3,5-dimethyl-phenyl)-4-(3-piperidin-1-...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-Buserelin to GnRH receptor in rat pituitary membranes.				Bioorg Med Chem Lett 9: 2615-20 (1999) BindingDB Entry DOI: 10.7270/Q2TD9WK0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50081126 (7-Chloro-4-(3-dimethylamino-propoxy)-3-phenyl-1H-q...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-Buserelin to GnRH receptor in rat pituitary membranes.				Bioorg Med Chem Lett 9: 2615-20 (1999) BindingDB Entry DOI: 10.7270/Q2TD9WK0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50081132 (7-Chloro-4-(1-methyl-piperidin-2-ylmethoxy)-3-phen...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-Buserelin to GnRH receptor in rat pituitary membranes.				Bioorg Med Chem Lett 9: 2615-20 (1999) BindingDB Entry DOI: 10.7270/Q2TD9WK0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50056638 (7-Chloro-3-phenyl-4-(pyridin-2-ylmethoxy)-1H-quino...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-Buserelin to GnRH receptor in rat pituitary membranes.				Bioorg Med Chem Lett 9: 2615-20 (1999) BindingDB Entry DOI: 10.7270/Q2TD9WK0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%