Affinity Data by PubMed id=10662686

PubMed code 10662686

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cathepsin B (Homo sapiens (Human))	BDBM36812 (CA-074) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	5.5	25
University of California, San Francisco					Assay Description Inhibition assay using pre-treatment of recombinant cathepsin-L-like cysteine protease cruzain lacking the carboxy-terminal domain or cathepsin B fr...				Chem Biol 7: 27-38 (2000) Article DOI: 10.1016/s1074-5521(00)00061-2 BindingDB Entry DOI: 10.7270/Q24B2ZN5
University of California, San Francisco					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM36813 (CA-074b) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	5.5	25
University of California, San Francisco					Assay Description Inhibition assay using pre-treatment of recombinant cathepsin-L-like cysteine protease cruzain lacking the carboxy-terminal domain or cathepsin B fr...				Chem Biol 7: 27-38 (2000) Article DOI: 10.1016/s1074-5521(00)00061-2 BindingDB Entry DOI: 10.7270/Q24B2ZN5
University of California, San Francisco					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM36814 (MB-074) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	5.5	25
University of California, San Francisco					Assay Description Inhibition assay using pre-treatment of recombinant cathepsin-L-like cysteine protease cruzain lacking the carboxy-terminal domain or cathepsin B fr...				Chem Biol 7: 27-38 (2000) Article DOI: 10.1016/s1074-5521(00)00061-2 BindingDB Entry DOI: 10.7270/Q24B2ZN5
University of California, San Francisco					More data for this Ligand-Target Pair
Procathepsin L [114-333,T223A] (Homo sapiens (Human))	BDBM36814 (MB-074) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	5.5	25
University of California, San Francisco					Assay Description Inhibition assay using pre-treatment of recombinant cathepsin-L-like cysteine protease cruzain lacking the carboxy-terminal domain or cathepsin B fr...				Chem Biol 7: 27-38 (2000) Article DOI: 10.1016/s1074-5521(00)00061-2 BindingDB Entry DOI: 10.7270/Q24B2ZN5
University of California, San Francisco					More data for this Ligand-Target Pair
Procathepsin L [114-333,T223A] (Homo sapiens (Human))	BDBM36813 (CA-074b) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	5.5	25
University of California, San Francisco					Assay Description Inhibition assay using pre-treatment of recombinant cathepsin-L-like cysteine protease cruzain lacking the carboxy-terminal domain or cathepsin B fr...				Chem Biol 7: 27-38 (2000) Article DOI: 10.1016/s1074-5521(00)00061-2 BindingDB Entry DOI: 10.7270/Q24B2ZN5
University of California, San Francisco					More data for this Ligand-Target Pair
Procathepsin L [114-333,T223A] (Homo sapiens (Human))	BDBM36812 (CA-074) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	5.5	25
University of California, San Francisco					Assay Description Inhibition assay using pre-treatment of recombinant cathepsin-L-like cysteine protease cruzain lacking the carboxy-terminal domain or cathepsin B fr...				Chem Biol 7: 27-38 (2000) Article DOI: 10.1016/s1074-5521(00)00061-2 BindingDB Entry DOI: 10.7270/Q24B2ZN5
University of California, San Francisco					More data for this Ligand-Target Pair

* indicates data uncertainty>20%