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PubMed code 10737736

Compile data set for download or QSAR
Found 19 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cytosolic phospholipase A2


(Homo sapiens (Human))		BDBM50085993
PNG
((E)-N-(((2S,4R)-4-((biphenyl-2-ylmethyl)(isobutyl)...)
Show SMILES CC(C)CN(Cc1ccccc1-c1ccccc1)[C@@H]1C[C@@H](CNC(=O)C=Cc2ccc(C=C3SC(O)=NC3=O)cc2)N(C1)C(=O)c1ccccc1C(=O)c1ccc(F)cc1F |w:31.32,26.28,c:37|
Show InChI InChI=1S/C49H44F2N4O5S/c1-31(2)28-54(29-35-12-6-7-13-39(35)34-10-4-3-5-11-34)38-26-37(27-52-45(56)23-20-32-16-18-33(19-17-32)24-44-47(58)53-49(60)61-44)55(30-38)48(59)41-15-9-8-14-40(41)46(57)42-22-21-36(50)25-43(42)51/h3-25,31,37-38H,26-30H2,1-2H3,(H,52,56)(H,53,58,60)/t37-,38+/m0/s1
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n/an/a 1.80n/an/an/an/an/an/a



Shionogi & Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of Human cPLA2 alpha using Enzyme assay(PC/DOG assay)

J Med Chem 43: 1041-4 (2000)


BindingDB Entry DOI: 10.7270/Q27P8XMZ
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Homo sapiens (Human))		BDBM50085984
PNG
(CHEMBL9161 | N-[1-[2-(2,4-Difluoro-benzoyl)-benzoy...)
Show SMILES CC(C)Cc1cccc(c1O[C@@H]1C[C@@H](CNC(=O)c2ccc(C=C3SC(O)=NC3=O)cc2)N(C1)C(=O)c1ccccc1C(=O)c1ccc(F)cc1F)-c1ccccc1C(C)C |w:22.22,c:27|
Show InChI InChI=1S/C49H45F2N3O6S/c1-28(2)22-32-10-9-15-39(37-12-6-5-11-36(37)29(3)4)45(32)60-35-25-34(26-52-46(56)31-18-16-30(17-19-31)23-43-47(57)53-49(59)61-43)54(27-35)48(58)40-14-8-7-13-38(40)44(55)41-21-20-33(50)24-42(41)51/h5-21,23-24,28-29,34-35H,22,25-27H2,1-4H3,(H,52,56)(H,53,57,59)/t34-,35+/m0/s1
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n/an/a 2.10n/an/an/an/an/an/a



Shionogi & Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of Human cPLA2 alpha using Enzyme assay(PC/DOG assay)

J Med Chem 43: 1041-4 (2000)


BindingDB Entry DOI: 10.7270/Q27P8XMZ
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Homo sapiens (Human))		BDBM50085986
PNG
(CHEMBL267258 | N-{4-(Biphenyl-2-ylmethyl-isobutyl-...)
Show SMILES CC(C)CN(Cc1ccccc1-c1ccccc1)[C@@H]1C[C@@H](CNC(=O)C=Cc2ccc(C=C3SC(O)=NC3=O)cc2)N(C1)C(=O)c1ccccc1C(=O)c1ccc(F)cc1 |w:31.32,26.28,c:37|
Show InChI InChI=1S/C49H45FN4O5S/c1-32(2)29-53(30-37-12-6-7-13-41(37)35-10-4-3-5-11-35)40-27-39(28-51-45(55)25-20-33-16-18-34(19-17-33)26-44-47(57)52-49(59)60-44)54(31-40)48(58)43-15-9-8-14-42(43)46(56)36-21-23-38(50)24-22-36/h3-26,32,39-40H,27-31H2,1-2H3,(H,51,55)(H,52,57,59)/t39-,40+/m0/s1
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n/an/a 3.10n/an/an/an/an/an/a



Shionogi & Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of Human cPLA2 alpha using Enzyme assay(PC/DOG assay)

J Med Chem 43: 1041-4 (2000)


BindingDB Entry DOI: 10.7270/Q27P8XMZ
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Homo sapiens (Human))		BDBM50085987
PNG
(4-(2,4-Dioxo-thiazolidin-5-ylidenemethyl)-N-[1-[2-...)
Show SMILES CC(C)Cc1cccc(c1O[C@@H]1C[C@@H](CNC(=O)c2ccc(C=C3SC(O)=NC3=O)cc2)N(C1)C(=O)c1ccccc1C(=O)c1ccc(F)cc1)-c1ccccc1C(C)C |w:22.22,c:27|
Show InChI InChI=1S/C49H46FN3O6S/c1-29(2)24-34-10-9-15-41(39-12-6-5-11-38(39)30(3)4)45(34)59-37-26-36(27-51-46(55)33-18-16-31(17-19-33)25-43-47(56)52-49(58)60-43)53(28-37)48(57)42-14-8-7-13-40(42)44(54)32-20-22-35(50)23-21-32/h5-23,25,29-30,36-37H,24,26-28H2,1-4H3,(H,51,55)(H,52,56,58)/t36-,37+/m0/s1
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n/an/a 5.30n/an/an/an/an/an/a



Shionogi & Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of Human cPLA2 alpha using Enzyme assay(PC/DOG assay)

J Med Chem 43: 1041-4 (2000)


BindingDB Entry DOI: 10.7270/Q27P8XMZ
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Homo sapiens (Human))		BDBM50085994
PNG
(CHEMBL8970 | N-{4-(Biphenyl-2-ylmethyl-isobutyl-am...)
Show SMILES CC(C)CN(Cc1ccccc1-c1ccccc1)[C@@H]1C[C@@H](CNC(=O)c2ccc(C=C3SC(O)=NC3=O)cc2)N(C1)C(=O)c1ccccc1C(=O)c1ccc(F)cc1F |w:29.30,c:35|
Show InChI InChI=1S/C47H42F2N4O5S/c1-29(2)26-52(27-33-12-6-7-13-37(33)31-10-4-3-5-11-31)36-24-35(25-50-44(55)32-18-16-30(17-19-32)22-42-45(56)51-47(58)59-42)53(28-36)46(57)39-15-9-8-14-38(39)43(54)40-21-20-34(48)23-41(40)49/h3-23,29,35-36H,24-28H2,1-2H3,(H,50,55)(H,51,56,58)/t35-,36+/m0/s1
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n/an/a 6.20n/an/an/an/an/an/a



Shionogi & Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of Human cPLA2 alpha using Enzyme assay(PC/DOG assay)

J Med Chem 43: 1041-4 (2000)


BindingDB Entry DOI: 10.7270/Q27P8XMZ
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Homo sapiens (Human))		BDBM50085980
PNG
(CHEMBL428996 | N-{4-(Biphenyl-2-ylmethyl-isobutyl-...)
Show SMILES CC(C)CN(Cc1ccccc1-c1ccccc1)[C@@H]1C[C@@H](CNC(=O)c2ccc(C=C3SC(O)=NC3=O)cc2)N(C1)C(=O)c1ccccc1C(=O)c1ccc(F)cc1 |w:29.30,c:35|
Show InChI InChI=1S/C47H43FN4O5S/c1-30(2)27-51(28-35-12-6-7-13-39(35)32-10-4-3-5-11-32)38-25-37(26-49-44(54)34-18-16-31(17-19-34)24-42-45(55)50-47(57)58-42)52(29-38)46(56)41-15-9-8-14-40(41)43(53)33-20-22-36(48)23-21-33/h3-24,30,37-38H,25-29H2,1-2H3,(H,49,54)(H,50,55,57)/t37-,38+/m0/s1
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n/an/a 21n/an/an/an/an/an/a



Shionogi & Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of Human cPLA2 alpha using Enzyme assay(PC/DOG assay)

J Med Chem 43: 1041-4 (2000)


BindingDB Entry DOI: 10.7270/Q27P8XMZ
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Homo sapiens (Human))		BDBM50085997
PNG
(CHEMBL266374 | N-{4-(2-Bromo-6-isobutyl-phenoxy)-1...)
Show SMILES CC(C)Cc1cccc(Br)c1O[C@@H]1C[C@@H](CNC(=O)c2ccc(C=C3SC(O)=NC3=O)cc2)N(C1)C(=O)c1ccccc1C(=O)c1ccc(F)cc1F |w:23.23,c:28|
Show InChI InChI=1S/C40H34BrF2N3O6S/c1-22(2)16-25-6-5-9-32(41)36(25)52-28-19-27(20-44-37(48)24-12-10-23(11-13-24)17-34-38(49)45-40(51)53-34)46(21-28)39(50)30-8-4-3-7-29(30)35(47)31-15-14-26(42)18-33(31)43/h3-15,17-18,22,27-28H,16,19-21H2,1-2H3,(H,44,48)(H,45,49,51)/t27-,28+/m0/s1
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n/an/a 22n/an/an/an/an/an/a



Shionogi & Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of Human cPLA2 alpha using Enzyme assay(PC/DOG assay)

J Med Chem 43: 1041-4 (2000)


BindingDB Entry DOI: 10.7270/Q27P8XMZ
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Homo sapiens (Human))		BDBM50085990
PNG
(CHEMBL268434 | N-{4-(Biphenyl-2-ylmethylsulfanyl)-...)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(cc1)C(=O)NC[C@@H]1C[C@H](CN1C(=O)c1ccccc1C(=O)c1ccc(F)cc1)SCc1ccccc1-c1ccccc1 |w:7.8,t:1|
Show InChI InChI=1S/C43H34FN3O5S2/c44-32-20-18-29(19-21-32)39(48)36-12-6-7-13-37(36)42(51)47-25-34(53-26-31-10-4-5-11-35(31)28-8-2-1-3-9-28)23-33(47)24-45-40(49)30-16-14-27(15-17-30)22-38-41(50)46-43(52)54-38/h1-22,33-34H,23-26H2,(H,45,49)(H,46,50,52)/t33-,34+/m0/s1
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n/an/a 34n/an/an/an/an/an/a



Shionogi & Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of Human cPLA2 alpha using Enzyme assay(PC/DOG assay)

J Med Chem 43: 1041-4 (2000)


BindingDB Entry DOI: 10.7270/Q27P8XMZ
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Homo sapiens (Human))		BDBM50085991
PNG
(CHEMBL268896 | N-{4-(2-Bromo-6-isobutyl-phenoxy)-1...)
Show SMILES CC(C)Cc1cccc(Br)c1O[C@@H]1C[C@@H](CNC(=O)c2ccc(C=C3SC(O)=NC3=O)cc2)N(C1)C(=O)c1ccccc1C(=O)c1ccc(F)cc1 |w:23.23,c:28|
Show InChI InChI=1S/C40H35BrFN3O6S/c1-23(2)18-27-6-5-9-33(41)36(27)51-30-20-29(21-43-37(47)26-12-10-24(11-13-26)19-34-38(48)44-40(50)52-34)45(22-30)39(49)32-8-4-3-7-31(32)35(46)25-14-16-28(42)17-15-25/h3-17,19,23,29-30H,18,20-22H2,1-2H3,(H,43,47)(H,44,48,50)/t29-,30+/m0/s1
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n/an/a 38n/an/an/an/an/an/a



Shionogi & Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of Human cPLA2 alpha using Enzyme assay(PC/DOG assay)

J Med Chem 43: 1041-4 (2000)


BindingDB Entry DOI: 10.7270/Q27P8XMZ
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Homo sapiens (Human))		BDBM50085983
PNG
(CHEMBL267697 | N-{4-(Biphenyl-2-ylmethoxy)-1-[2-(2...)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(cc1)C(=O)NC[C@@H]1C[C@H](CN1C(=O)c1ccccc1C(=O)c1ccc(F)cc1F)OCc1ccccc1-c1ccccc1 |w:7.8,t:1|
Show InChI InChI=1S/C43H33F2N3O6S/c44-30-18-19-36(37(45)21-30)39(49)34-12-6-7-13-35(34)42(52)48-24-32(54-25-29-10-4-5-11-33(29)27-8-2-1-3-9-27)22-31(48)23-46-40(50)28-16-14-26(15-17-28)20-38-41(51)47-43(53)55-38/h1-21,31-32H,22-25H2,(H,46,50)(H,47,51,53)/t31-,32+/m0/s1
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n/an/a 49n/an/an/an/an/an/a



Shionogi & Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of Human cPLA2 alpha using Enzyme assay(PC/DOG assay)

J Med Chem 43: 1041-4 (2000)


BindingDB Entry DOI: 10.7270/Q27P8XMZ
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Homo sapiens (Human))		BDBM50085988
PNG
(CHEMBL416517 | N-{4-(Biphenyl-2-yloxy)-1-[2-(4-flu...)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(cc1)C(=O)NC[C@@H]1C[C@H](CN1C(=O)c1ccccc1C(=O)c1ccc(F)cc1)Oc1ccccc1-c1ccccc1 |w:7.8,t:1|
Show InChI InChI=1S/C42H32FN3O6S/c43-30-20-18-28(19-21-30)38(47)34-11-4-5-12-35(34)41(50)46-25-32(52-36-13-7-6-10-33(36)27-8-2-1-3-9-27)23-31(46)24-44-39(48)29-16-14-26(15-17-29)22-37-40(49)45-42(51)53-37/h1-22,31-32H,23-25H2,(H,44,48)(H,45,49,51)/t31-,32+/m0/s1
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n/an/a 69n/an/an/an/an/an/a



Shionogi & Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of Human cPLA2 alpha using Enzyme assay(PC/DOG assay)

J Med Chem 43: 1041-4 (2000)


BindingDB Entry DOI: 10.7270/Q27P8XMZ
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Homo sapiens (Human))		BDBM50085981
PNG
(CHEMBL268419 | N-{4-(Biphenyl-2-ylmethylsulfanyl)-...)
Show SMILES Fc1ccc(cc1)C(=O)c1ccccc1C(=O)N1C[C@@H](C[C@H]1CNC(=O)c1ccc(C=C2SC(S)=NC2=O)cc1)SCc1ccccc1-c1ccccc1 |w:30.32,c:37|
Show InChI InChI=1S/C43H34FN3O4S3/c44-32-20-18-29(19-21-32)39(48)36-12-6-7-13-37(36)42(51)47-25-34(53-26-31-10-4-5-11-35(31)28-8-2-1-3-9-28)23-33(47)24-45-40(49)30-16-14-27(15-17-30)22-38-41(50)46-43(52)54-38/h1-22,33-34H,23-26H2,(H,45,49)(H,46,50,52)/t33-,34+/m0/s1
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n/an/a 72n/an/an/an/an/an/a



Shionogi & Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of Human cPLA2 alpha using Enzyme assay(PC/DOG assay)

J Med Chem 43: 1041-4 (2000)


BindingDB Entry DOI: 10.7270/Q27P8XMZ
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Homo sapiens (Human))		BDBM50085982
PNG
(CHEMBL9277 | N-{4-(Biphenyl-2-ylmethoxy)-1-[2-(4-f...)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(cc1)C(=O)NC[C@@H]1C[C@H](CN1C(=O)c1ccccc1C(=O)c1ccc(F)cc1)OCc1ccccc1-c1ccccc1 |w:7.8,t:1|
Show InChI InChI=1S/C43H34FN3O6S/c44-32-20-18-29(19-21-32)39(48)36-12-6-7-13-37(36)42(51)47-25-34(53-26-31-10-4-5-11-35(31)28-8-2-1-3-9-28)23-33(47)24-45-40(49)30-16-14-27(15-17-30)22-38-41(50)46-43(52)54-38/h1-22,33-34H,23-26H2,(H,45,49)(H,46,50,52)/t33-,34+/m0/s1
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n/an/a 78n/an/an/an/an/an/a



Shionogi & Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of Human cPLA2 alpha using Enzyme assay(PC/DOG assay)

J Med Chem 43: 1041-4 (2000)


BindingDB Entry DOI: 10.7270/Q27P8XMZ
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Homo sapiens (Human))		BDBM50085989
PNG
(CHEMBL428827 | N-{4-(Biphenyl-2-yloxy)-1-[2-(4-flu...)
Show SMILES Fc1ccc(cc1)C(=O)c1ccccc1C(=O)N1C[C@@H](C[C@H]1CNC(=O)c1ccc(C=C2SC(S)=NC2=O)cc1)Oc1ccccc1-c1ccccc1 |w:30.32,c:37|
Show InChI InChI=1S/C42H32FN3O5S2/c43-30-20-18-28(19-21-30)38(47)34-11-4-5-12-35(34)41(50)46-25-32(51-36-13-7-6-10-33(36)27-8-2-1-3-9-27)23-31(46)24-44-39(48)29-16-14-26(15-17-29)22-37-40(49)45-42(52)53-37/h1-22,31-32H,23-25H2,(H,44,48)(H,45,49,52)/t31-,32+/m0/s1
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n/an/a 83n/an/an/an/an/an/a



Shionogi & Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of Human cPLA2 alpha using Enzyme assay(PC/DOG assay)

J Med Chem 43: 1041-4 (2000)


BindingDB Entry DOI: 10.7270/Q27P8XMZ
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Homo sapiens (Human))		BDBM50085985
PNG
(CHEMBL428653 | N-{4-(Biphenyl-2-ylmethoxy)-1-[2-(4...)
Show SMILES Fc1ccc(cc1)C(=O)c1ccccc1C(=O)N1C[C@@H](C[C@H]1CNC(=O)c1ccc(C=C2SC(S)=NC2=O)cc1)OCc1ccccc1-c1ccccc1 |w:30.32,c:37|
Show InChI InChI=1S/C43H34FN3O5S2/c44-32-20-18-29(19-21-32)39(48)36-12-6-7-13-37(36)42(51)47-25-34(52-26-31-10-4-5-11-35(31)28-8-2-1-3-9-28)23-33(47)24-45-40(49)30-16-14-27(15-17-30)22-38-41(50)46-43(53)54-38/h1-22,33-34H,23-26H2,(H,45,49)(H,46,50,53)/t33-,34+/m0/s1
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n/an/a 90n/an/an/an/an/an/a



Shionogi & Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of Human cPLA2 alpha using Enzyme assay(PC/DOG assay)

J Med Chem 43: 1041-4 (2000)


BindingDB Entry DOI: 10.7270/Q27P8XMZ
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Homo sapiens (Human))		BDBM50085992
PNG
(CHEMBL268905 | N-[(2S,4R)-1-(2-Benzoyl-benzoyl)-4-...)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(cc1)C(=O)NC[C@@H]1C[C@H](CN1C(=O)c1ccccc1C(=O)c1ccccc1)OCc1ccccc1-c1ccccc1 |w:7.8,t:1|
Show InChI InChI=1S/C43H35N3O6S/c47-39(30-13-5-2-6-14-30)36-17-9-10-18-37(36)42(50)46-26-34(52-27-32-15-7-8-16-35(32)29-11-3-1-4-12-29)24-33(46)25-44-40(48)31-21-19-28(20-22-31)23-38-41(49)45-43(51)53-38/h1-23,33-34H,24-27H2,(H,44,48)(H,45,49,51)/t33-,34+/m0/s1
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n/an/a 165n/an/an/an/an/an/a



Shionogi & Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of Human cPLA2 alpha using Enzyme assay(PC/DOG assay)

J Med Chem 43: 1041-4 (2000)


BindingDB Entry DOI: 10.7270/Q27P8XMZ
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Homo sapiens (Human))		BDBM50085998
PNG
(1,1,1-Trifluoro-docosa-7,10,13,16-tetraen-3-one | ...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)CC(F)(F)F
Show InChI InChI=1S/C22H33F3O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21(26)20-22(23,24)25/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-20H2,1H3/b7-6-,10-9-,13-12-,16-15-
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n/an/a 420n/an/an/an/an/an/a



Shionogi & Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of Human cPLA2 alpha using Enzyme assay(PC/DOG assay)

J Med Chem 43: 1041-4 (2000)


BindingDB Entry DOI: 10.7270/Q27P8XMZ
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Homo sapiens (Human))		BDBM50085999
PNG
(CHEMBL268904 | N-[1-(3-Benzoyl-benzoyl)-4-(bipheny...)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(cc1)C(=O)NC[C@@H]1C[C@H](CN1C(=O)c1cccc(c1)C(=O)c1ccccc1)OCc1ccccc1-c1ccccc1 |w:7.8,t:1|
Show InChI InChI=1S/C43H35N3O6S/c47-39(30-12-5-2-6-13-30)32-15-9-16-33(23-32)42(50)46-26-36(52-27-34-14-7-8-17-37(34)29-10-3-1-4-11-29)24-35(46)25-44-40(48)31-20-18-28(19-21-31)22-38-41(49)45-43(51)53-38/h1-23,35-36H,24-27H2,(H,44,48)(H,45,49,51)/t35-,36+/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



Shionogi & Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of Human cPLA2 alpha using Enzyme assay(PC/DOG assay)

J Med Chem 43: 1041-4 (2000)


BindingDB Entry DOI: 10.7270/Q27P8XMZ
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Homo sapiens (Human))		BDBM50085996
PNG
(CHEMBL266580 | N-[1-(4-Benzoyl-benzoyl)-4-(bipheny...)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(cc1)C(=O)NC[C@@H]1C[C@H](CN1C(=O)c1ccc(cc1)C(=O)c1ccccc1)OCc1ccccc1-c1ccccc1 |w:7.8,t:1|
Show InChI InChI=1S/C43H35N3O6S/c47-39(30-11-5-2-6-12-30)31-19-21-33(22-20-31)42(50)46-26-36(52-27-34-13-7-8-14-37(34)29-9-3-1-4-10-29)24-35(46)25-44-40(48)32-17-15-28(16-18-32)23-38-41(49)45-43(51)53-38/h1-23,35-36H,24-27H2,(H,44,48)(H,45,49,51)/t35-,36+/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



Shionogi & Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of Human cPLA2 alpha using Enzyme assay(PC/DOG assay)

J Med Chem 43: 1041-4 (2000)


BindingDB Entry DOI: 10.7270/Q27P8XMZ
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%