Affinity Data by PubMed id=10762041

PubMed code 10762041

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Trypanothione reductase (Trypanosoma cruzi)	BDBM50087158 (5-(8-Hydroxy-3-methyl-1,4-dioxo-1,4-dihydro-naphth...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Université Lille II Curated by ChEMBL					Assay Description Concentration required for inhibition of Trypanothione reductase (TcTR) from Trypanosoma cruzi in the presence of 50 uM TS2 as substrate				Bioorg Med Chem Lett 10: 631-5 (2000) BindingDB Entry DOI: 10.7270/Q2V9879F
Université Lille II Curated by ChEMBL					More data for this Ligand-Target Pair
Trypanothione reductase (Trypanosoma cruzi)	BDBM50087157 (5-(8-Hydroxy-3-methyl-1,4-dioxo-1,4-dihydro-naphth...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Université Lille II Curated by ChEMBL					Assay Description Concentration required for inhibition of Trypanothione reductase (TcTR) from Trypanosoma cruzi in the presence of 50 uM TS2 as substrate				Bioorg Med Chem Lett 10: 631-5 (2000) BindingDB Entry DOI: 10.7270/Q2V9879F
Université Lille II Curated by ChEMBL					More data for this Ligand-Target Pair
Trypanothione reductase (Trypanosoma cruzi)	BDBM50087156 (5-{3-[4-(3-Dibutylamino-propylcarbamoyl)-butyl]-8-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Université Lille II Curated by ChEMBL					Assay Description Concentration required for inhibition of Trypanothione reductase (TcTR) from Trypanosoma cruzi in the presence of 50 uM TS2 as substrate				Bioorg Med Chem Lett 10: 631-5 (2000) BindingDB Entry DOI: 10.7270/Q2V9879F
Université Lille II Curated by ChEMBL					More data for this Ligand-Target Pair
Trypanothione reductase (Trypanosoma cruzi)	BDBM50087155 (5-(3-Methyl-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Lille II Curated by ChEMBL					Assay Description Concentration required for inhibition of Trypanothione reductase (TcTR) from Trypanosoma cruzi in the presence of 50 uM TS2 as substrate				Bioorg Med Chem Lett 10: 631-5 (2000) BindingDB Entry DOI: 10.7270/Q2V9879F
Université Lille II Curated by ChEMBL					More data for this Ligand-Target Pair
Trypanothione reductase (Trypanosoma cruzi)	BDBM50012070 (5-Hydroxy-2-methyl-[1,4]naphthoquinone \| 5-hydroxy...) Show SMILES CC1=CC(=O)c2c(O)cccc2C1=O \|t:1\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Université Lille II Curated by ChEMBL					Assay Description Concentration required for inhibition of Trypanothione reductase (TcTR) from Trypanosoma cruzi in the presence of 50 uM TS2 as substrate				Bioorg Med Chem Lett 10: 631-5 (2000) BindingDB Entry DOI: 10.7270/Q2V9879F
Université Lille II Curated by ChEMBL					More data for this Ligand-Target Pair
Trypanothione reductase (Trypanosoma cruzi)	BDBM24778 (2-methyl-1,4-dihydronaphthalene-1,4-dione \| 2-meth...) Show SMILES CC1=CC(=O)c2ccccc2C1=O \|t:1\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	5.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Université Lille II Curated by ChEMBL					Assay Description Concentration required for inhibition of Trypanothione reductase (TcTR) from Trypanosoma cruzi in the presence of 50 uM TS2 as substrate				Bioorg Med Chem Lett 10: 631-5 (2000) BindingDB Entry DOI: 10.7270/Q2V9879F
Université Lille II Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%