Affinity Data by PubMed id=11412983

PubMed code 11412983

Found 9 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Metabotropic glutamate receptor 1 (RAT)	BDBM50100942 ((2S,4S)-2-ammonio-4-carboxy-4-hydroxybutanoate) Show SMILES [NH3+][C@@H](C[C@H](O)C(O)=O)C([O-])=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a
Universit£ Ren£ Descartes Curated by ChEMBL					Assay Description Agonist activity in rat at mGlu1a receptor expressed in HEK293 cells				Bioorg Med Chem Lett 11: 1569-72 (2001) BindingDB Entry DOI: 10.7270/Q2M61KRJ
Universit£ Ren£ Descartes Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM17657 ((2S)-2-aminopentanedioic acid \| (S)-Glu \| D-Glutam...) Show SMILES N[C@@H](CCC(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
Universit£ Ren£ Descartes Curated by ChEMBL					Assay Description Agonist activity in rat at Metabotropic glutamate receptor 1 expressed in HEK293 cells				Bioorg Med Chem Lett 11: 1569-72 (2001) BindingDB Entry DOI: 10.7270/Q2M61KRJ
Universit£ Ren£ Descartes Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Rattus norvegicus)	BDBM50100942 ((2S,4S)-2-ammonio-4-carboxy-4-hydroxybutanoate) Show SMILES [NH3+][C@@H](C[C@H](O)C(O)=O)C([O-])=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.37E+5	n/a	n/a	n/a	n/a
Universit£ Ren£ Descartes Curated by ChEMBL					Assay Description Agonist activity in rat at mGlu2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 11: 1569-72 (2001) BindingDB Entry DOI: 10.7270/Q2M61KRJ
Universit£ Ren£ Descartes Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Rattus norvegicus)	BDBM17657 ((2S)-2-aminopentanedioic acid \| (S)-Glu \| D-Glutam...) Show SMILES N[C@@H](CCC(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a
Universit£ Ren£ Descartes Curated by ChEMBL					Assay Description Agonist activity in rat at Metabotropic glutamate receptor 2 expressed in HEK293 cells				Bioorg Med Chem Lett 11: 1569-72 (2001) BindingDB Entry DOI: 10.7270/Q2M61KRJ
Universit£ Ren£ Descartes Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 8 (Rattus norvegicus (Rat))	BDBM50100941 ((2S,4R)-2-ammonio-4-carboxy-4-hydroxybutanoate) Show SMILES [NH3+][C@@H](C[C@@H](O)C(O)=O)C([O-])=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	6.90E+4	n/a	n/a	n/a	n/a
Universit£ Ren£ Descartes Curated by ChEMBL					Assay Description Agonist activity in rat at mGlu8a receptor expressed in HEK293 cells				Bioorg Med Chem Lett 11: 1569-72 (2001) BindingDB Entry DOI: 10.7270/Q2M61KRJ
Universit£ Ren£ Descartes Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Rattus norvegicus)	BDBM50100941 ((2S,4R)-2-ammonio-4-carboxy-4-hydroxybutanoate) Show SMILES [NH3+][C@@H](C[C@@H](O)C(O)=O)C([O-])=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.61E+5	n/a	n/a	n/a	n/a
Universit£ Ren£ Descartes Curated by ChEMBL					Assay Description Agonist activity in rat at mGlu2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 11: 1569-72 (2001) BindingDB Entry DOI: 10.7270/Q2M61KRJ
Universit£ Ren£ Descartes Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 8 (Rattus norvegicus (Rat))	BDBM17657 ((2S)-2-aminopentanedioic acid \| (S)-Glu \| D-Glutam...) Show SMILES N[C@@H](CCC(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a
Universit£ Ren£ Descartes Curated by ChEMBL					Assay Description Agonist activity in rat at Metabotropic glutamate receptor 8 expressed in HEK293 cells				Bioorg Med Chem Lett 11: 1569-72 (2001) BindingDB Entry DOI: 10.7270/Q2M61KRJ
Universit£ Ren£ Descartes Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50100941 ((2S,4R)-2-ammonio-4-carboxy-4-hydroxybutanoate) Show SMILES [NH3+][C@@H](C[C@@H](O)C(O)=O)C([O-])=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.73E+5	n/a	n/a	n/a	n/a
Universit£ Ren£ Descartes Curated by ChEMBL					Assay Description Agonist activity in rat at mGlu1a receptor expressed in HEK293 cells				Bioorg Med Chem Lett 11: 1569-72 (2001) BindingDB Entry DOI: 10.7270/Q2M61KRJ
Universit£ Ren£ Descartes Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 8 (Rattus norvegicus (Rat))	BDBM50100942 ((2S,4S)-2-ammonio-4-carboxy-4-hydroxybutanoate) Show SMILES [NH3+][C@@H](C[C@H](O)C(O)=O)C([O-])=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	5.30E+4	n/a	n/a	n/a	n/a
Universit£ Ren£ Descartes Curated by ChEMBL					Assay Description Agonist activity in rat at mGlu8a receptor expressed in HEK293 cells				Bioorg Med Chem Lett 11: 1569-72 (2001) BindingDB Entry DOI: 10.7270/Q2M61KRJ
Universit£ Ren£ Descartes Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%