Affinity Data by PubMed id=11428922

PubMed code 11428922

Found 21 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50101427 ((R)-2-(5-nitro-1H-indol-3-yl)-2-oxo-N-(1-phenyleth...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Inhibition of [3H]-flumazenil binding to rat alpha1-beta2-gamma2 GABA-A receptor subunits expressed in HEK293 cells				J Med Chem 44: 2286-97 (2001) BindingDB Entry DOI: 10.7270/Q2T152WS
Università di Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50101429 (2-(1H-Indol-3-yl)-N-(4-nitro-benzyl)-2-oxo-acetami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Inhibition of [3H]-flumazenil binding to rat alpha1-beta2-gamma2 GABA-A receptor subunits expressed in HEK293 cells				J Med Chem 44: 2286-97 (2001) BindingDB Entry DOI: 10.7270/Q2T152WS
Università di Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50066949 ((1H-Indol-3-yl)-oxo-acetic acid N'-(4-nitro-phenyl...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Inhibition of [3H]-flumazenil binding to rat alpha1-beta2-gamma2 GABA-A receptor subunits expressed in HEK293 cells				J Med Chem 44: 2286-97 (2001) BindingDB Entry DOI: 10.7270/Q2T152WS
Università di Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2 (Rattus norvegicus (Rat)-RAT)	BDBM50066949 ((1H-Indol-3-yl)-oxo-acetic acid N'-(4-nitro-phenyl...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Inhibition of [3H]-flumazenil binding to rat alpha3-beta2-gamma2 GABA-A receptor subunits expressed in HEK293 cells				J Med Chem 44: 2286-97 (2001) BindingDB Entry DOI: 10.7270/Q2T152WS
Università di Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50055247 (CHEMBL75306 \| N-(4-Methoxy-benzyl)-2-(5-nitro-1H-i...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Inhibition of [3H]-flumazenil binding to rat alpha1-beta2-gamma2 GABA-A receptor subunits expressed in HEK293 cells				J Med Chem 44: 2286-97 (2001) BindingDB Entry DOI: 10.7270/Q2T152WS
Università di Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-5/beta-3/gamma-2 (Rattus norvegicus (Rat)-RAT)	BDBM50066949 ((1H-Indol-3-yl)-oxo-acetic acid N'-(4-nitro-phenyl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Inhibition of [3H]-flumazenil binding to rat alpha5-beta3-gamma2 GABA-A receptor subunits expressed in HEK293 cells				J Med Chem 44: 2286-97 (2001) BindingDB Entry DOI: 10.7270/Q2T152WS
Università di Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM26266 (Ambien \| CHEMBL911 \| Dalparan \| N,N-dimethyl-2-[6-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Inhibition of [3H]-flumazenil specific binding at rat GABA-A alpha1-beta2-gamma2 receptor subunits expressed in HEK293 cells				J Med Chem 44: 2286-97 (2001) BindingDB Entry DOI: 10.7270/Q2T152WS
Università di Pisa Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-5/beta-3/gamma-2 (Rattus norvegicus (Rat)-RAT)	BDBM50101429 (2-(1H-Indol-3-yl)-N-(4-nitro-benzyl)-2-oxo-acetami...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Inhibition of [3H]-flumazenil binding to rat alpha5-beta3-gamma2 GABA-A receptor subunits expressed in HEK293 cells				J Med Chem 44: 2286-97 (2001) BindingDB Entry DOI: 10.7270/Q2T152WS
Università di Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-5/beta-3/gamma-2 (Rattus norvegicus (Rat)-RAT)	BDBM50268784 ((R)-N-(2,3-dihydro-1H-inden-1-yl)-2-(5-nitro-1H-in...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	95	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Inhibition of [3H]-flumazenil binding to rat alpha5-beta3-gamma2 GABA-A receptor subunits expressed in HEK293 cells				J Med Chem 44: 2286-97 (2001) BindingDB Entry DOI: 10.7270/Q2T152WS
Università di Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-5/beta-3/gamma-2 (Rattus norvegicus (Rat)-RAT)	BDBM50055247 (CHEMBL75306 \| N-(4-Methoxy-benzyl)-2-(5-nitro-1H-i...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	126	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Inhibition of [3H]-flumazenil binding to rat alpha5-beta3-gamma2 GABA-A receptor subunits expressed in HEK293 cells				J Med Chem 44: 2286-97 (2001) BindingDB Entry DOI: 10.7270/Q2T152WS
Università di Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2 (Rattus norvegicus (Rat)-RAT)	BDBM50055247 (CHEMBL75306 \| N-(4-Methoxy-benzyl)-2-(5-nitro-1H-i...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	137	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Inhibition of [3H]-flumazenil binding to rat alpha3-beta2-gamma2 GABA-A receptor subunits expressed in HEK293 cells				J Med Chem 44: 2286-97 (2001) BindingDB Entry DOI: 10.7270/Q2T152WS
Università di Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50089770 (1-(1,3-Dihydro-isoindol-2-yl)-2-(1H-indol-3-yl)-et...) Show SMILES O=C(N1Cc2ccccc2C1)C(=O)c1c[nH]c2ccccc12 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	224	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Inhibition of [3H]-flumazenil binding to rat alpha1-beta2-gamma2 GABA-A receptor subunits expressed in HEK293 cells				J Med Chem 44: 2286-97 (2001) BindingDB Entry DOI: 10.7270/Q2T152WS
Università di Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-5/beta-3/gamma-2 (Rattus norvegicus (Rat)-RAT)	BDBM50101427 ((R)-2-(5-nitro-1H-indol-3-yl)-2-oxo-N-(1-phenyleth...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	239	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Inhibition of [3H]-flumazenil binding to rat alpha5-beta3-gamma2 GABA-A receptor subunits expressed in HEK293 cells				J Med Chem 44: 2286-97 (2001) BindingDB Entry DOI: 10.7270/Q2T152WS
Università di Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2 (Rattus norvegicus (Rat)-RAT)	BDBM50101427 ((R)-2-(5-nitro-1H-indol-3-yl)-2-oxo-N-(1-phenyleth...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	283	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Inhibition of [3H]-flumazenil binding to rat alpha3-beta2-gamma2 GABA-A receptor subunits expressed in HEK293 cells				J Med Chem 44: 2286-97 (2001) BindingDB Entry DOI: 10.7270/Q2T152WS
Università di Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2 (Rattus norvegicus (Rat)-RAT)	BDBM26266 (Ambien \| CHEMBL911 \| Dalparan \| N,N-dimethyl-2-[6-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	765	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Inhibition of [3H]-flumazenil binding to rat GABA-A receptor alpha3-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 44: 2286-97 (2001) BindingDB Entry DOI: 10.7270/Q2T152WS
Università di Pisa Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50101422 ((R)-2-(1H-indol-3-yl)-2-oxo-N-(1-phenylethyl)aceta...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Inhibition of [3H]-flumazenil binding to rat alpha1-beta2-gamma2 GABA-A receptor subunits expressed in HEK293 cells				J Med Chem 44: 2286-97 (2001) BindingDB Entry DOI: 10.7270/Q2T152WS
Università di Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2 (Rattus norvegicus (Rat)-RAT)	BDBM50101429 (2-(1H-Indol-3-yl)-N-(4-nitro-benzyl)-2-oxo-acetami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Inhibition of [3H]-flumazenil binding to rat alpha3-beta2-gamma2 GABA-A receptor subunits expressed in HEK293 cells				J Med Chem 44: 2286-97 (2001) BindingDB Entry DOI: 10.7270/Q2T152WS
Università di Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2 (Rattus norvegicus (Rat)-RAT)	BDBM50268784 ((R)-N-(2,3-dihydro-1H-inden-1-yl)-2-(5-nitro-1H-in...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.96E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Inhibition of [3H]-flumazenil binding to rat alpha3-beta2-gamma2 GABA-A receptor subunits expressed in HEK293 cells				J Med Chem 44: 2286-97 (2001) BindingDB Entry DOI: 10.7270/Q2T152WS
Università di Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-5/beta-3/gamma-2 (Rattus norvegicus (Rat)-RAT)	BDBM50268744 ((R)-N-(2,3-dihydro-1H-inden-1-yl)-2-(1H-indol-3-yl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.16E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Inhibition of [3H]-flumazenil binding to rat alpha5-beta3-gamma2 GABA-A receptor subunits expressed in HEK293 cells				J Med Chem 44: 2286-97 (2001) BindingDB Entry DOI: 10.7270/Q2T152WS
Università di Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2 (Rattus norvegicus (Rat)-RAT)	BDBM50089770 (1-(1,3-Dihydro-isoindol-2-yl)-2-(1H-indol-3-yl)-et...) Show SMILES O=C(N1Cc2ccccc2C1)C(=O)c1c[nH]c2ccccc12 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Inhibition of [3H]-flumazenil binding to rat alpha3-beta2-gamma2 GABA-A receptor subunits expressed in HEK293 cells				J Med Chem 44: 2286-97 (2001) BindingDB Entry DOI: 10.7270/Q2T152WS
Università di Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-5/beta-3/gamma-2 (Rattus norvegicus (Rat)-RAT)	BDBM50101422 ((R)-2-(1H-indol-3-yl)-2-oxo-N-(1-phenylethyl)aceta...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Inhibition of [3H]-flumazenil binding to rat alpha5-beta3-gamma2 GABA-A receptor subunits expressed in HEK293 cells				J Med Chem 44: 2286-97 (2001) BindingDB Entry DOI: 10.7270/Q2T152WS
Università di Pisa Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%