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PubMed code 11597417

Compile data set for download or QSAR
Found 73 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(2) dopamine receptor


(BOVINE)		BDBM50054067
PNG
((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...)
Show SMILES CCCN(CCC)[C@@H]1CCc2ccc(O)cc2C1
Show InChI InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3/t15-/m1/s1
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 5n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-Pramipexole from high affinity binding sites of bovine cloned D2 receptors stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50105731
PNG
((S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-...)
Show SMILES CCCN(CCC)[C@H]1CCn2c(C1)ccc2C=O
Show InChI InChI=1S/C15H24N2O/c1-3-8-16(9-4-2)13-7-10-17-14(11-13)5-6-15(17)12-18/h5-6,12-13H,3-4,7-11H2,1-2H3/t13-/m0/s1
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 6n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from bovine cloned Dopamine receptor D2 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50105731
PNG
((S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-...)
Show SMILES CCCN(CCC)[C@H]1CCn2c(C1)ccc2C=O
Show InChI InChI=1S/C15H24N2O/c1-3-8-16(9-4-2)13-7-10-17-14(11-13)5-6-15(17)12-18/h5-6,12-13H,3-4,7-11H2,1-2H3/t13-/m0/s1
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 6n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from human cloned Dopamine receptor D3 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50054067
PNG
((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...)
Show SMILES CCCN(CCC)[C@@H]1CCc2ccc(O)cc2C1
Show InChI InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3/t15-/m1/s1
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 8n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from human cloned Dopamine receptor D3 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50054067
PNG
((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...)
Show SMILES CCCN(CCC)[C@@H]1CCc2ccc(O)cc2C1
Show InChI InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3/t15-/m1/s1
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 8n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-Pramipexole from high affinity binding sites of bovine cloned D2 receptors stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(BOVINE)		BDBM50105731
PNG
((S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-...)
Show SMILES CCCN(CCC)[C@H]1CCn2c(C1)ccc2C=O
Show InChI InChI=1S/C15H24N2O/c1-3-8-16(9-4-2)13-7-10-17-14(11-13)5-6-15(17)12-18/h5-6,12-13H,3-4,7-11H2,1-2H3/t13-/m0/s1
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 21n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-Pramipexole from high affinity binding sites of bovine cloned D2 receptors stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(BOVINE)		BDBM50105730
PNG
(((S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-...)
Show SMILES CCCN(CCC)[C@H]1CCn2c(CO)ccc2C1
Show InChI InChI=1S/C15H26N2O/c1-3-8-16(9-4-2)13-7-10-17-14(11-13)5-6-15(17)12-18/h5-6,13,18H,3-4,7-12H2,1-2H3/t13-/m0/s1
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 87n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]pramipexole from high affinity binding sites of bovine cloned D2 receptors stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(BOVINE)		BDBM50105731
PNG
((S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-...)
Show SMILES CCCN(CCC)[C@H]1CCn2c(C1)ccc2C=O
Show InChI InChI=1S/C15H24N2O/c1-3-8-16(9-4-2)13-7-10-17-14(11-13)5-6-15(17)12-18/h5-6,12-13H,3-4,7-11H2,1-2H3/t13-/m0/s1
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 90n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from bovine cloned Dopamine receptor D2 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(BOVINE)		BDBM50105731
PNG
((S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-...)
Show SMILES CCCN(CCC)[C@H]1CCn2c(C1)ccc2C=O
Show InChI InChI=1S/C15H24N2O/c1-3-8-16(9-4-2)13-7-10-17-14(11-13)5-6-15(17)12-18/h5-6,12-13H,3-4,7-11H2,1-2H3/t13-/m0/s1
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 90n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from bovine cloned Dopamine receptor D2 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(BOVINE)		BDBM50105726
PNG
(CHEMBL318924 | Dipropyl-(R)-5,6,7,8-tetrahydro-ind...)
Show SMILES CCCN(CCC)[C@@H]1CCn2cccc2C1
Show InChI InChI=1S/C14H24N2/c1-3-8-15(9-4-2)14-7-11-16-10-5-6-13(16)12-14/h5-6,10,14H,3-4,7-9,11-12H2,1-2H3/t14-/m1/s1
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 150n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-Pramipexole from high affinity binding sites of bovine cloned D2 receptors stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(BOVINE)		BDBM50105739
PNG
(((S)-3-Methyl-5,6,7,8-tetrahydro-indolizin-7-yl)-d...)
Show SMILES CCCN(CCC)[C@H]1CCn2c(C)ccc2C1
Show InChI InChI=1S/C15H26N2/c1-4-9-16(10-5-2)14-8-11-17-13(3)6-7-15(17)12-14/h6-7,14H,4-5,8-12H2,1-3H3/t14-/m0/s1
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 150n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from bovine cloned Dopamine receptor D2 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(BOVINE)		BDBM50105727
PNG
(((R)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-...)
Show SMILES CCCN(CCC)[C@@H]1CCn2ccc(CO)c2C1
Show InChI InChI=1S/C15H26N2O/c1-3-7-16(8-4-2)14-6-10-17-9-5-13(12-18)15(17)11-14/h5,9,14,18H,3-4,6-8,10-12H2,1-2H3/t14-/m1/s1
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 200n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-Pramipexole from high affinity binding sites of bovine cloned D2 receptors stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50105727
PNG
(((R)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-...)
Show SMILES CCCN(CCC)[C@@H]1CCn2ccc(CO)c2C1
Show InChI InChI=1S/C15H26N2O/c1-3-7-16(8-4-2)14-6-10-17-9-5-13(12-18)15(17)11-14/h5,9,14,18H,3-4,6-8,10-12H2,1-2H3/t14-/m1/s1
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 330n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from human cloned Dopamine receptor D3 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(BOVINE)		BDBM50105738
PNG
((R)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-...)
Show SMILES CCCN(CCC)[C@@H]1CCn2ccc(C=O)c2C1
Show InChI InChI=1S/C15H24N2O/c1-3-7-16(8-4-2)14-6-10-17-9-5-13(12-18)15(17)11-14/h5,9,12,14H,3-4,6-8,10-11H2,1-2H3/t14-/m1/s1
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 380n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-Pramipexole from high affinity binding sites of bovine cloned D2 receptors stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(BOVINE)		BDBM50105735
PNG
(((S)-1-Methyl-5,6,7,8-tetrahydro-indolizin-7-yl)-d...)
Show SMILES CCCN(CCC)[C@H]1CCn2ccc(C)c2C1
Show InChI InChI=1S/C15H26N2/c1-4-8-16(9-5-2)14-7-11-17-10-6-13(3)15(17)12-14/h6,10,14H,4-5,7-9,11-12H2,1-3H3/t14-/m0/s1
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 380n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from bovine cloned Dopamine receptor D2 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50105730
PNG
(((S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-...)
Show SMILES CCCN(CCC)[C@H]1CCn2c(CO)ccc2C1
Show InChI InChI=1S/C15H26N2O/c1-3-8-16(9-4-2)13-7-10-17-14(11-13)5-6-15(17)12-18/h5-6,13,18H,3-4,7-12H2,1-2H3/t13-/m0/s1
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 420n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from human cloned Dopamine receptor D3 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50105739
PNG
(((S)-3-Methyl-5,6,7,8-tetrahydro-indolizin-7-yl)-d...)
Show SMILES CCCN(CCC)[C@H]1CCn2c(C)ccc2C1
Show InChI InChI=1S/C15H26N2/c1-4-9-16(10-5-2)14-8-11-17-13(3)6-7-15(17)12-14/h6-7,14H,4-5,8-12H2,1-3H3/t14-/m0/s1
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 430n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from human cloned Dopamine receptor D3 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(BOVINE)		BDBM50105734
PNG
(((R)-3-Methyl-5,6,7,8-tetrahydro-indolizin-7-yl)-d...)
Show SMILES CCCN(CCC)[C@@H]1CCn2c(C)ccc2C1
Show InChI InChI=1S/C15H26N2/c1-4-9-16(10-5-2)14-8-11-17-13(3)6-7-15(17)12-14/h6-7,14H,4-5,8-12H2,1-3H3/t14-/m1/s1
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 430n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-Pramipexole from high affinity binding sites of bovine cloned D2 receptors stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50105738
PNG
((R)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-...)
Show SMILES CCCN(CCC)[C@@H]1CCn2ccc(C=O)c2C1
Show InChI InChI=1S/C15H24N2O/c1-3-7-16(8-4-2)14-6-10-17-9-5-13(12-18)15(17)11-14/h5,9,12,14H,3-4,6-8,10-11H2,1-2H3/t14-/m1/s1
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 510n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from human cloned Dopamine receptor D3 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50105726
PNG
(CHEMBL318924 | Dipropyl-(R)-5,6,7,8-tetrahydro-ind...)
Show SMILES CCCN(CCC)[C@@H]1CCn2cccc2C1
Show InChI InChI=1S/C14H24N2/c1-3-8-15(9-4-2)14-7-11-16-10-5-6-13(16)12-14/h5-6,10,14H,3-4,7-9,11-12H2,1-2H3/t14-/m1/s1
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 560n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from human cloned Dopamine receptor D3 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50105734
PNG
(((R)-3-Methyl-5,6,7,8-tetrahydro-indolizin-7-yl)-d...)
Show SMILES CCCN(CCC)[C@@H]1CCn2c(C)ccc2C1
Show InChI InChI=1S/C15H26N2/c1-4-9-16(10-5-2)14-8-11-17-13(3)6-7-15(17)12-14/h6-7,14H,4-5,8-12H2,1-3H3/t14-/m1/s1
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 590n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from human cloned Dopamine receptor D3 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(BOVINE)		BDBM50105724
PNG
(((S)-2-Methyl-5,6,7,8-tetrahydro-indolizin-7-yl)-d...)
Show SMILES CCCN(CCC)[C@H]1CCn2cc(C)cc2C1
Show InChI InChI=1S/C15H26N2/c1-4-7-16(8-5-2)14-6-9-17-12-13(3)10-15(17)11-14/h10,12,14H,4-9,11H2,1-3H3/t14-/m0/s1
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 640n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from human cloned Dopamine receptor D3 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50105735
PNG
(((S)-1-Methyl-5,6,7,8-tetrahydro-indolizin-7-yl)-d...)
Show SMILES CCCN(CCC)[C@H]1CCn2ccc(C)c2C1
Show InChI InChI=1S/C15H26N2/c1-4-8-16(9-5-2)14-7-11-17-10-6-13(3)15(17)12-14/h6,10,14H,4-5,7-9,11-12H2,1-3H3/t14-/m0/s1
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 750n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from human cloned Dopamine receptor D3 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50105724
PNG
(((S)-2-Methyl-5,6,7,8-tetrahydro-indolizin-7-yl)-d...)
Show SMILES CCCN(CCC)[C@H]1CCn2cc(C)cc2C1
Show InChI InChI=1S/C15H26N2/c1-4-7-16(8-5-2)14-6-9-17-12-13(3)10-15(17)11-14/h10,12,14H,4-9,11H2,1-3H3/t14-/m0/s1
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 770n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from human cloned Dopamine receptor D3 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(BOVINE)		BDBM50105733
PNG
(((R)-2-Methyl-5,6,7,8-tetrahydro-indolizin-7-yl)-d...)
Show SMILES CCCN(CCC)[C@@H]1CCn2cc(C)cc2C1
Show InChI InChI=1S/C15H26N2/c1-4-7-16(8-5-2)14-6-9-17-12-13(3)10-15(17)11-14/h10,12,14H,4-9,11H2,1-3H3/t14-/m1/s1
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 800n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-Pramipexole from high affinity binding sites of bovine cloned D2 receptors stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(BOVINE)		BDBM50105736
PNG
(((R)-1-Methyl-5,6,7,8-tetrahydro-indolizin-7-yl)-d...)
Show SMILES CCCN(CCC)[C@@H]1CCn2ccc(C)c2C1
Show InChI InChI=1S/C15H26N2/c1-4-8-16(9-5-2)14-7-11-17-10-6-13(3)15(17)12-14/h6,10,14H,4-5,7-9,11-12H2,1-3H3/t14-/m1/s1
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 1.00E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-Pramipexole from high affinity binding sites of bovine cloned D2 receptors stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(BOVINE)		BDBM50105737
PNG
(((R)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-...)
Show SMILES CCCN(CCC)[C@@H]1CCn2cc(CO)cc2C1
Show InChI InChI=1S/C15H26N2O/c1-3-6-16(7-4-2)14-5-8-17-11-13(12-18)9-15(17)10-14/h9,11,14,18H,3-8,10,12H2,1-2H3/t14-/m1/s1
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 1.00E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-Pramipexole from high affinity binding sites of bovine cloned D2 receptors stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(BOVINE)		BDBM50105734
PNG
(((R)-3-Methyl-5,6,7,8-tetrahydro-indolizin-7-yl)-d...)
Show SMILES CCCN(CCC)[C@@H]1CCn2c(C)ccc2C1
Show InChI InChI=1S/C15H26N2/c1-4-9-16(10-5-2)14-8-11-17-13(3)6-7-15(17)12-14/h6-7,14H,4-5,8-12H2,1-3H3/t14-/m1/s1
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 1.30E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from bovine cloned Dopamine receptor D2 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50105733
PNG
(((R)-2-Methyl-5,6,7,8-tetrahydro-indolizin-7-yl)-d...)
Show SMILES CCCN(CCC)[C@@H]1CCn2cc(C)cc2C1
Show InChI InChI=1S/C15H26N2/c1-4-7-16(8-5-2)14-6-9-17-12-13(3)10-15(17)11-14/h10,12,14H,4-9,11H2,1-3H3/t14-/m1/s1
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 1.30E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from human cloned Dopamine receptor D3 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50105737
PNG
(((R)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-...)
Show SMILES CCCN(CCC)[C@@H]1CCn2cc(CO)cc2C1
Show InChI InChI=1S/C15H26N2O/c1-3-6-16(7-4-2)14-5-8-17-11-13(12-18)9-15(17)10-14/h9,11,14,18H,3-8,10,12H2,1-2H3/t14-/m1/s1
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 1.40E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from human cloned Dopamine receptor D3 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(BOVINE)		BDBM50105732
PNG
((S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-...)
Show SMILES CCCN(CCC)[C@H]1CCn2ccc(C=O)c2C1
Show InChI InChI=1S/C15H24N2O/c1-3-7-16(8-4-2)14-6-10-17-9-5-13(12-18)15(17)11-14/h5,9,12,14H,3-4,6-8,10-11H2,1-2H3/t14-/m0/s1
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 1.60E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-Pramipexole from high affinity binding sites of bovine cloned D2 receptors stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(BOVINE)		BDBM50105729
PNG
((R)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-...)
Show SMILES CCCN(CCC)[C@@H]1CCn2c(C1)ccc2C=O
Show InChI InChI=1S/C15H24N2O/c1-3-8-16(9-4-2)13-7-10-17-14(11-13)5-6-15(17)12-18/h5-6,12-13H,3-4,7-11H2,1-2H3/t13-/m1/s1
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 1.70E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from bovine cloned Dopamine receptor D2 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50105729
PNG
((R)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-...)
Show SMILES CCCN(CCC)[C@@H]1CCn2c(C1)ccc2C=O
Show InChI InChI=1S/C15H24N2O/c1-3-8-16(9-4-2)13-7-10-17-14(11-13)5-6-15(17)12-18/h5-6,12-13H,3-4,7-11H2,1-2H3/t13-/m1/s1
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 1.80E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from human cloned Dopamine receptor D3 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50105736
PNG
(((R)-1-Methyl-5,6,7,8-tetrahydro-indolizin-7-yl)-d...)
Show SMILES CCCN(CCC)[C@@H]1CCn2ccc(C)c2C1
Show InChI InChI=1S/C15H26N2/c1-4-8-16(9-5-2)14-7-11-17-10-6-13(3)15(17)12-14/h6,10,14H,4-5,7-9,11-12H2,1-3H3/t14-/m1/s1
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 2.10E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from human cloned Dopamine receptor D3 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50105732
PNG
((S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-...)
Show SMILES CCCN(CCC)[C@H]1CCn2ccc(C=O)c2C1
Show InChI InChI=1S/C15H24N2O/c1-3-7-16(8-4-2)14-6-10-17-9-5-13(12-18)15(17)11-14/h5,9,12,14H,3-4,6-8,10-11H2,1-2H3/t14-/m0/s1
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 3.60E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from human cloned Dopamine receptor D3 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(BOVINE)		BDBM50105739
PNG
(((S)-3-Methyl-5,6,7,8-tetrahydro-indolizin-7-yl)-d...)
Show SMILES CCCN(CCC)[C@H]1CCn2c(C)ccc2C1
Show InChI InChI=1S/C15H26N2/c1-4-9-16(10-5-2)14-8-11-17-13(3)6-7-15(17)12-14/h6-7,14H,4-5,8-12H2,1-3H3/t14-/m0/s1
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 3.80E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from bovine cloned Dopamine receptor D2 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(BOVINE)		BDBM50105735
PNG
(((S)-1-Methyl-5,6,7,8-tetrahydro-indolizin-7-yl)-d...)
Show SMILES CCCN(CCC)[C@H]1CCn2ccc(C)c2C1
Show InChI InChI=1S/C15H26N2/c1-4-8-16(9-5-2)14-7-11-17-10-6-13(3)15(17)12-14/h6,10,14H,4-5,7-9,11-12H2,1-3H3/t14-/m0/s1
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 4.00E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from bovine cloned Dopamine receptor D2 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(BOVINE)		BDBM50105726
PNG
(CHEMBL318924 | Dipropyl-(R)-5,6,7,8-tetrahydro-ind...)
Show SMILES CCCN(CCC)[C@@H]1CCn2cccc2C1
Show InChI InChI=1S/C14H24N2/c1-3-8-15(9-4-2)14-7-11-16-10-5-6-13(16)12-14/h5-6,10,14H,3-4,7-9,11-12H2,1-2H3/t14-/m1/s1
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 4.10E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-Pramipexole from high affinity binding sites of bovine cloned D2 receptors stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(BOVINE)		BDBM50105725
PNG
(((R)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-...)
Show SMILES CCCN(CCC)[C@@H]1CCn2c(CO)ccc2C1
Show InChI InChI=1S/C15H26N2O/c1-3-8-16(9-4-2)13-7-10-17-14(11-13)5-6-15(17)12-18/h5-6,13,18H,3-4,7-12H2,1-2H3/t13-/m1/s1
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 4.70E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-Pramipexole from high affinity binding sites of bovine cloned D2 receptors stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(BOVINE)		BDBM50105730
PNG
(((S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-...)
Show SMILES CCCN(CCC)[C@H]1CCn2c(CO)ccc2C1
Show InChI InChI=1S/C15H26N2O/c1-3-8-16(9-4-2)13-7-10-17-14(11-13)5-6-15(17)12-18/h5-6,13,18H,3-4,7-12H2,1-2H3/t13-/m0/s1
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 5.50E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from bovine cloned Dopamine receptor D2 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(BOVINE)		BDBM50105732
PNG
((S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-...)
Show SMILES CCCN(CCC)[C@H]1CCn2ccc(C=O)c2C1
Show InChI InChI=1S/C15H24N2O/c1-3-7-16(8-4-2)14-6-10-17-9-5-13(12-18)15(17)11-14/h5,9,12,14H,3-4,6-8,10-11H2,1-2H3/t14-/m0/s1
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 5.90E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from bovine cloned Dopamine receptor D2 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(BOVINE)		BDBM50105727
PNG
(((R)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-...)
Show SMILES CCCN(CCC)[C@@H]1CCn2ccc(CO)c2C1
Show InChI InChI=1S/C15H26N2O/c1-3-7-16(8-4-2)14-6-10-17-9-5-13(12-18)15(17)11-14/h5,9,14,18H,3-4,6-8,10-12H2,1-2H3/t14-/m1/s1
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 6.10E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from bovine cloned Dopamine receptor D2 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50105725
PNG
(((R)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-...)
Show SMILES CCCN(CCC)[C@@H]1CCn2c(CO)ccc2C1
Show InChI InChI=1S/C15H26N2O/c1-3-8-16(9-4-2)13-7-10-17-14(11-13)5-6-15(17)12-18/h5-6,13,18H,3-4,7-12H2,1-2H3/t13-/m1/s1
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 7.40E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from human cloned Dopamine receptor D3 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(BOVINE)		BDBM50105728
PNG
(((S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-...)
Show SMILES CCCN(CCC)[C@H]1CCn2ccc(CO)c2C1
Show InChI InChI=1S/C15H26N2O/c1-3-7-16(8-4-2)14-6-10-17-9-5-13(12-18)15(17)11-14/h5,9,14,18H,3-4,6-8,10-12H2,1-2H3/t14-/m0/s1
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 8.00E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-Pramipexole from high affinity binding sites of bovine cloned D2 receptors stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50105740
PNG
(((S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-...)
Show SMILES CCCN(CCC)[C@H]1CCn2cc(CO)cc2C1
Show InChI InChI=1S/C15H26N2O/c1-3-6-16(7-4-2)14-5-8-17-11-13(12-18)9-15(17)10-14/h9,11,14,18H,3-8,10,12H2,1-2H3/t14-/m0/s1
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 8.60E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from human cloned Dopamine receptor D3 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(BOVINE)		BDBM50105724
PNG
(((S)-2-Methyl-5,6,7,8-tetrahydro-indolizin-7-yl)-d...)
Show SMILES CCCN(CCC)[C@H]1CCn2cc(C)cc2C1
Show InChI InChI=1S/C15H26N2/c1-4-7-16(8-5-2)14-6-9-17-12-13(3)10-15(17)11-14/h10,12,14H,4-9,11H2,1-3H3/t14-/m0/s1
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 9.60E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from bovine cloned Dopamine receptor D2 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50105728
PNG
(((S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-...)
Show SMILES CCCN(CCC)[C@H]1CCn2ccc(CO)c2C1
Show InChI InChI=1S/C15H26N2O/c1-3-7-16(8-4-2)14-6-10-17-9-5-13(12-18)15(17)11-14/h5,9,14,18H,3-4,6-8,10-12H2,1-2H3/t14-/m0/s1
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 9.70E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from human cloned Dopamine receptor D3 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(BOVINE)		BDBM50105738
PNG
((R)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-...)
Show SMILES CCCN(CCC)[C@@H]1CCn2ccc(C=O)c2C1
Show InChI InChI=1S/C15H24N2O/c1-3-7-16(8-4-2)14-6-10-17-9-5-13(12-18)15(17)11-14/h5,9,12,14H,3-4,6-8,10-11H2,1-2H3/t14-/m1/s1
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 1.20E+4n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from bovine cloned Dopamine receptor D2 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(BOVINE)		BDBM50105734
PNG
(((R)-3-Methyl-5,6,7,8-tetrahydro-indolizin-7-yl)-d...)
Show SMILES CCCN(CCC)[C@@H]1CCn2c(C)ccc2C1
Show InChI InChI=1S/C15H26N2/c1-4-9-16(10-5-2)14-8-11-17-13(3)6-7-15(17)12-14/h6-7,14H,4-5,8-12H2,1-3H3/t14-/m1/s1
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 1.20E+4n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-SCH-23,390 from bovine cloned Dopamine receptor D1 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(BOVINE)		BDBM50105736
PNG
(((R)-1-Methyl-5,6,7,8-tetrahydro-indolizin-7-yl)-d...)
Show SMILES CCCN(CCC)[C@@H]1CCn2ccc(C)c2C1
Show InChI InChI=1S/C15H26N2/c1-4-8-16(9-5-2)14-7-11-17-10-6-13(3)15(17)12-14/h6,10,14H,4-5,7-9,11-12H2,1-3H3/t14-/m1/s1
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 1.20E+4n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-Pramipexole from high affinity binding sites of bovine cloned D2 receptors stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(BOVINE)		BDBM50105730
PNG
(((S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-...)
Show SMILES CCCN(CCC)[C@H]1CCn2c(CO)ccc2C1
Show InChI InChI=1S/C15H26N2O/c1-3-8-16(9-4-2)13-7-10-17-14(11-13)5-6-15(17)12-18/h5-6,13,18H,3-4,7-12H2,1-2H3/t13-/m0/s1
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 1.30E+4n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-SCH-23,390 from bovine cloned Dopamine receptor D1 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(BOVINE)		BDBM50105740
PNG
(((S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-...)
Show SMILES CCCN(CCC)[C@H]1CCn2cc(CO)cc2C1
Show InChI InChI=1S/C15H26N2O/c1-3-6-16(7-4-2)14-5-8-17-11-13(12-18)9-15(17)10-14/h9,11,14,18H,3-8,10,12H2,1-2H3/t14-/m0/s1
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 1.30E+4n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-Pramipexole from high affinity binding sites of bovine cloned D2 receptors stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(BOVINE)		BDBM50105733
PNG
(((R)-2-Methyl-5,6,7,8-tetrahydro-indolizin-7-yl)-d...)
Show SMILES CCCN(CCC)[C@@H]1CCn2cc(C)cc2C1
Show InChI InChI=1S/C15H26N2/c1-4-7-16(8-5-2)14-6-9-17-12-13(3)10-15(17)11-14/h10,12,14H,4-9,11H2,1-3H3/t14-/m1/s1
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 1.70E+4n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-Pramipexole from high affinity binding sites of bovine cloned D2 receptors stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(BOVINE)		BDBM50105729
PNG
((R)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-...)
Show SMILES CCCN(CCC)[C@@H]1CCn2c(C1)ccc2C=O
Show InChI InChI=1S/C15H24N2O/c1-3-8-16(9-4-2)13-7-10-17-14(11-13)5-6-15(17)12-18/h5-6,12-13H,3-4,7-11H2,1-2H3/t13-/m1/s1
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 2.10E+4n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from bovine cloned Dopamine receptor D2 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(BOVINE)		BDBM50105731
PNG
((S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-...)
Show SMILES CCCN(CCC)[C@H]1CCn2c(C1)ccc2C=O
Show InChI InChI=1S/C15H24N2O/c1-3-8-16(9-4-2)13-7-10-17-14(11-13)5-6-15(17)12-18/h5-6,12-13H,3-4,7-11H2,1-2H3/t13-/m0/s1
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 2.60E+4n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-SCH-23,390 from bovine cloned Dopamine receptor D1 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(BOVINE)		BDBM50105739
PNG
(((S)-3-Methyl-5,6,7,8-tetrahydro-indolizin-7-yl)-d...)
Show SMILES CCCN(CCC)[C@H]1CCn2c(C)ccc2C1
Show InChI InChI=1S/C15H26N2/c1-4-9-16(10-5-2)14-8-11-17-13(3)6-7-15(17)12-14/h6-7,14H,4-5,8-12H2,1-3H3/t14-/m0/s1
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 2.90E+4n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-SCH-23,390 from bovine cloned Dopamine receptor D1 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(BOVINE)		BDBM50105737
PNG
(((R)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-...)
Show SMILES CCCN(CCC)[C@@H]1CCn2cc(CO)cc2C1
Show InChI InChI=1S/C15H26N2O/c1-3-6-16(7-4-2)14-5-8-17-11-13(12-18)9-15(17)10-14/h9,11,14,18H,3-8,10,12H2,1-2H3/t14-/m1/s1
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 3.40E+4n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-Pramipexole from high affinity binding sites of bovine cloned D2 receptors stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(BOVINE)		BDBM50105725
PNG
(((R)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-...)
Show SMILES CCCN(CCC)[C@@H]1CCn2c(CO)ccc2C1
Show InChI InChI=1S/C15H26N2O/c1-3-8-16(9-4-2)13-7-10-17-14(11-13)5-6-15(17)12-18/h5-6,13,18H,3-4,7-12H2,1-2H3/t13-/m1/s1
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 3.70E+4n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from bovine cloned Dopamine receptor D2 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(BOVINE)		BDBM50105724
PNG
(((S)-2-Methyl-5,6,7,8-tetrahydro-indolizin-7-yl)-d...)
Show SMILES CCCN(CCC)[C@H]1CCn2cc(C)cc2C1
Show InChI InChI=1S/C15H26N2/c1-4-7-16(8-5-2)14-6-9-17-12-13(3)10-15(17)11-14/h10,12,14H,4-9,11H2,1-3H3/t14-/m0/s1
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 4.40E+4n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-SCH-23,390 from bovine cloned Dopamine receptor D1 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(BOVINE)		BDBM50105729
PNG
((R)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-...)
Show SMILES CCCN(CCC)[C@@H]1CCn2c(C1)ccc2C=O
Show InChI InChI=1S/C15H24N2O/c1-3-8-16(9-4-2)13-7-10-17-14(11-13)5-6-15(17)12-18/h5-6,12-13H,3-4,7-11H2,1-2H3/t13-/m1/s1
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 4.70E+4n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-SCH-23,390 from bovine cloned Dopamine receptor D1 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(BOVINE)		BDBM50105728
PNG
(((S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-...)
Show SMILES CCCN(CCC)[C@H]1CCn2ccc(CO)c2C1
Show InChI InChI=1S/C15H26N2O/c1-3-7-16(8-4-2)14-6-10-17-9-5-13(12-18)15(17)11-14/h5,9,14,18H,3-4,6-8,10-12H2,1-2H3/t14-/m0/s1
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 5.50E+4n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from bovine cloned Dopamine receptor D2 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(BOVINE)		BDBM50105735
PNG
(((S)-1-Methyl-5,6,7,8-tetrahydro-indolizin-7-yl)-d...)
Show SMILES CCCN(CCC)[C@H]1CCn2ccc(C)c2C1
Show InChI InChI=1S/C15H26N2/c1-4-8-16(9-5-2)14-7-11-17-10-6-13(3)15(17)12-14/h6,10,14H,4-5,7-9,11-12H2,1-3H3/t14-/m0/s1
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 6.80E+4n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-SCH-23,390 from bovine cloned Dopamine receptor D1 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(BOVINE)		BDBM50105736
PNG
(((R)-1-Methyl-5,6,7,8-tetrahydro-indolizin-7-yl)-d...)
Show SMILES CCCN(CCC)[C@@H]1CCn2ccc(C)c2C1
Show InChI InChI=1S/C15H26N2/c1-4-8-16(9-5-2)14-7-11-17-10-6-13(3)15(17)12-14/h6,10,14H,4-5,7-9,11-12H2,1-3H3/t14-/m1/s1
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 7.10E+4n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-SCH-23,390 from bovine cloned Dopamine receptor D1 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(BOVINE)		BDBM50105738
PNG
((R)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-...)
Show SMILES CCCN(CCC)[C@@H]1CCn2ccc(C=O)c2C1
Show InChI InChI=1S/C15H24N2O/c1-3-7-16(8-4-2)14-6-10-17-9-5-13(12-18)15(17)11-14/h5,9,12,14H,3-4,6-8,10-11H2,1-2H3/t14-/m1/s1
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 8.00E+4n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-SCH-23,390 from bovine cloned Dopamine receptor D1 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(BOVINE)		BDBM50105733
PNG
(((R)-2-Methyl-5,6,7,8-tetrahydro-indolizin-7-yl)-d...)
Show SMILES CCCN(CCC)[C@@H]1CCn2cc(C)cc2C1
Show InChI InChI=1S/C15H26N2/c1-4-7-16(8-5-2)14-6-9-17-12-13(3)10-15(17)11-14/h10,12,14H,4-9,11H2,1-3H3/t14-/m1/s1
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 8.30E+4n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-SCH-23,390 from bovine cloned Dopamine receptor D1 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(BOVINE)		BDBM50105737
PNG
(((R)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-...)
Show SMILES CCCN(CCC)[C@@H]1CCn2cc(CO)cc2C1
Show InChI InChI=1S/C15H26N2O/c1-3-6-16(7-4-2)14-5-8-17-11-13(12-18)9-15(17)10-14/h9,11,14,18H,3-8,10,12H2,1-2H3/t14-/m1/s1
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>1.00E+5n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-SCH-23,390 from bovine cloned Dopamine receptor D1 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(BOVINE)		BDBM50105740
PNG
(((S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-...)
Show SMILES CCCN(CCC)[C@H]1CCn2cc(CO)cc2C1
Show InChI InChI=1S/C15H26N2O/c1-3-6-16(7-4-2)14-5-8-17-11-13(12-18)9-15(17)10-14/h9,11,14,18H,3-8,10,12H2,1-2H3/t14-/m0/s1
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>1.00E+5n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-SCH-23,390 from bovine cloned Dopamine receptor D1 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(BOVINE)		BDBM50105727
PNG
(((R)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-...)
Show SMILES CCCN(CCC)[C@@H]1CCn2ccc(CO)c2C1
Show InChI InChI=1S/C15H26N2O/c1-3-7-16(8-4-2)14-6-10-17-9-5-13(12-18)15(17)11-14/h5,9,14,18H,3-4,6-8,10-12H2,1-2H3/t14-/m1/s1
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 1.00E+5n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-SCH-23,390 from bovine cloned Dopamine receptor D1 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(BOVINE)		BDBM50105732
PNG
((S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-...)
Show SMILES CCCN(CCC)[C@H]1CCn2ccc(C=O)c2C1
Show InChI InChI=1S/C15H24N2O/c1-3-7-16(8-4-2)14-6-10-17-9-5-13(12-18)15(17)11-14/h5,9,12,14H,3-4,6-8,10-11H2,1-2H3/t14-/m0/s1
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>1.00E+5n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-SCH-23,390 from bovine cloned Dopamine receptor D1 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(BOVINE)		BDBM50105728
PNG
(((S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-...)
Show SMILES CCCN(CCC)[C@H]1CCn2ccc(CO)c2C1
Show InChI InChI=1S/C15H26N2O/c1-3-7-16(8-4-2)14-6-10-17-9-5-13(12-18)15(17)11-14/h5,9,14,18H,3-4,6-8,10-12H2,1-2H3/t14-/m0/s1
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>1.00E+5n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-SCH-23,390 from bovine cloned Dopamine receptor D1 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(BOVINE)		BDBM50105726
PNG
(CHEMBL318924 | Dipropyl-(R)-5,6,7,8-tetrahydro-ind...)
Show SMILES CCCN(CCC)[C@@H]1CCn2cccc2C1
Show InChI InChI=1S/C14H24N2/c1-3-8-15(9-4-2)14-7-11-16-10-5-6-13(16)12-14/h5-6,10,14H,3-4,7-9,11-12H2,1-2H3/t14-/m1/s1
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>1.00E+5n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-SCH-23,390 from bovine cloned Dopamine receptor D1 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(BOVINE)		BDBM50105725
PNG
(((R)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-...)
Show SMILES CCCN(CCC)[C@@H]1CCn2c(CO)ccc2C1
Show InChI InChI=1S/C15H26N2O/c1-3-8-16(9-4-2)13-7-10-17-14(11-13)5-6-15(17)12-18/h5-6,13,18H,3-4,7-12H2,1-2H3/t13-/m1/s1
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>1.00E+5n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-SCH-23,390 from bovine cloned Dopamine receptor D1 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(BOVINE)		BDBM50105740
PNG
(((S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-...)
Show SMILES CCCN(CCC)[C@H]1CCn2cc(CO)cc2C1
Show InChI InChI=1S/C15H26N2O/c1-3-6-16(7-4-2)14-5-8-17-11-13(12-18)9-15(17)10-14/h9,11,14,18H,3-8,10,12H2,1-2H3/t14-/m0/s1
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>1.00E+5n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-spiperone from human cloned Dopamine receptor D3 stably expressed in CHO cells.

Bioorg Med Chem Lett 11: 2863-6 (2001)


BindingDB Entry DOI: 10.7270/Q2D799Q9
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%