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PubMed code 11741473

Compile data set for download or QSAR
Found 37 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tubulin beta-2B chain


(Bos taurus)
BDBM50107672
PNG
((3-Fluoro-phenyl)-(5-methoxy-1H-indol-2-yl)-methan...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)c1cccc(F)c1
Show InChI InChI=1S/C16H12FNO2/c1-20-13-5-6-14-11(8-13)9-15(18-14)16(19)10-3-2-4-12(17)7-10/h2-9,18H,1H3
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PubMed
n/an/a 390n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
Tubulin beta-2B chain


(Bos taurus)
BDBM50107658
PNG
((5-Methoxy-1H-indol-2-yl)-phenyl-methanone | (5-me...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)c1ccccc1
Show InChI InChI=1S/C16H13NO2/c1-19-13-7-8-14-12(9-13)10-15(17-14)16(18)11-5-3-2-4-6-11/h2-10,17H,1H3
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PubMed
n/an/a 530n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
Tubulin beta-2B chain


(Bos taurus)
BDBM50107678
PNG
((5-Methoxy-1H-indol-2-yl)-(3-methoxy-phenyl)-metha...)
Show SMILES COc1cccc(c1)C(=O)c1cc2cc(OC)ccc2[nH]1
Show InChI InChI=1S/C17H15NO3/c1-20-13-5-3-4-11(8-13)17(19)16-10-12-9-14(21-2)6-7-15(12)18-16/h3-10,18H,1-2H3
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n/an/a 530n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
Tubulin beta-2B chain


(Bos taurus)
BDBM50107677
PNG
((3-Hydroxy-phenyl)-(5-methoxy-1H-indol-2-yl)-metha...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)c1cccc(O)c1
Show InChI InChI=1S/C16H13NO3/c1-20-13-5-6-14-11(8-13)9-15(17-14)16(19)10-3-2-4-12(18)7-10/h2-9,17-18H,1H3
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n/an/a 660n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
Tubulin beta-2B chain


(Bos taurus)
BDBM50107656
PNG
((3,5-Dimethoxy-phenyl)-(5-methoxy-1H-indol-2-yl)-m...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)c1cc(OC)cc(OC)c1
Show InChI InChI=1S/C18H17NO4/c1-21-13-4-5-16-11(6-13)9-17(19-16)18(20)12-7-14(22-2)10-15(8-12)23-3/h4-10,19H,1-3H3
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n/an/a 810n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
Tubulin beta-2B chain


(Bos taurus)
BDBM50107676
PNG
((3,4-Dimethoxy-phenyl)-(5-methoxy-1H-indol-2-yl)-m...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)c1ccc(OC)c(OC)c1
Show InChI InChI=1S/C18H17NO4/c1-21-13-5-6-14-12(8-13)9-15(19-14)18(20)11-4-7-16(22-2)17(10-11)23-3/h4-10,19H,1-3H3
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n/an/a 810n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
Tubulin beta-2B chain


(Bos taurus)
BDBM50107674
PNG
(Butyric acid 3-(5-methoxy-1H-indole-2-carbonyl)-ph...)
Show SMILES CCCC(=O)Oc1cccc(c1)C(=O)c1cc2cc(OC)ccc2[nH]1
Show InChI InChI=1S/C20H19NO4/c1-3-5-19(22)25-16-7-4-6-13(10-16)20(23)18-12-14-11-15(24-2)8-9-17(14)21-18/h4,6-12,21H,3,5H2,1-2H3
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n/an/a 850n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
Tubulin beta-2B chain


(Bos taurus)
BDBM50107664
PNG
((5-Methoxy-1H-indol-2-yl)-(3-nitro-phenyl)-methano...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)c1cccc(c1)[N+]([O-])=O
Show InChI InChI=1S/C16H12N2O4/c1-22-13-5-6-14-11(8-13)9-15(17-14)16(19)10-3-2-4-12(7-10)18(20)21/h2-9,17H,1H3
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n/an/a 850n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
Tubulin beta-2B chain


(Bos taurus)
BDBM50107693
PNG
((5-Methyl-1H-indol-2-yl)-(3,4,5-trimethoxy-phenyl)...)
Show SMILES COc1cc(cc(OC)c1OC)C(=O)c1cc2cc(C)ccc2[nH]1
Show InChI InChI=1S/C19H19NO4/c1-11-5-6-14-12(7-11)8-15(20-14)18(21)13-9-16(22-2)19(24-4)17(10-13)23-3/h5-10,20H,1-4H3
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n/an/a 860n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
Tubulin beta-2B chain


(Bos taurus)
BDBM50107662
PNG
((3-Amino-phenyl)-(5-methoxy-1H-indol-2-yl)-methano...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)c1cccc(N)c1
Show InChI InChI=1S/C16H14N2O2/c1-20-13-5-6-14-11(8-13)9-15(18-14)16(19)10-3-2-4-12(17)7-10/h2-9,18H,17H2,1H3
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n/an/a 990n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
Tubulin beta-2B chain


(Bos taurus)
BDBM50107651
PNG
((5-Methoxy-1H-indol-2-yl)-(3,4,5-trimethoxy-phenyl...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)c1cc(OC)c(OC)c(OC)c1
Show InChI InChI=1S/C19H19NO5/c1-22-13-5-6-14-11(7-13)8-15(20-14)18(21)12-9-16(23-2)19(25-4)17(10-12)24-3/h5-10,20H,1-4H3
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n/an/a 990n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
Tubulin beta-2B chain


(Bos taurus)
BDBM50107663
PNG
((2-Fluoro-phenyl)-(5-methoxy-1H-indol-2-yl)-methan...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)c1ccccc1F
Show InChI InChI=1S/C16H12FNO2/c1-20-11-6-7-14-10(8-11)9-15(18-14)16(19)12-4-2-3-5-13(12)17/h2-9,18H,1H3
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n/an/a 1.00E+3n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
Tubulin beta-2B chain


(Bos taurus)
BDBM50107670
PNG
((5-Methoxy-1H-indol-2-yl)-(2-methoxy-phenyl)-metha...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)c1ccccc1OC
Show InChI InChI=1S/C17H15NO3/c1-20-12-7-8-14-11(9-12)10-15(18-14)17(19)13-5-3-4-6-16(13)21-2/h3-10,18H,1-2H3
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n/an/a 1.29E+3n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
Tubulin beta-2B chain


(Bos taurus)
BDBM50107671
PNG
((5-Methoxy-1H-indol-2-yl)-(3-trifluoromethyl-pheny...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C17H12F3NO2/c1-23-13-5-6-14-11(8-13)9-15(21-14)16(22)10-3-2-4-12(7-10)17(18,19)20/h2-9,21H,1H3
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n/an/a 1.50E+3n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
Tubulin beta-2B chain


(Bos taurus)
BDBM50107680
PNG
((5-Methoxy-1H-indol-2-yl)-p-tolyl-methanone | CHEM...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)c1ccc(C)cc1
Show InChI InChI=1S/C17H15NO2/c1-11-3-5-12(6-4-11)17(19)16-10-13-9-14(20-2)7-8-15(13)18-16/h3-10,18H,1-2H3
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n/an/a 1.50E+3n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
Tubulin beta-2B chain


(Bos taurus)
BDBM50107682
PNG
((5-Methoxy-1H-indol-2-yl)-(3-trifluoromethoxy-phen...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)c1cccc(OC(F)(F)F)c1
Show InChI InChI=1S/C17H12F3NO3/c1-23-12-5-6-14-11(8-12)9-15(21-14)16(22)10-3-2-4-13(7-10)24-17(18,19)20/h2-9,21H,1H3
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n/an/a 1.70E+3n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
Tubulin beta-2B chain


(Bos taurus)
BDBM50107673
PNG
((3-Difluoromethylsulfanyl-phenyl)-(5-methoxy-1H-in...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)c1cccc(SC(F)F)c1
Show InChI InChI=1S/C17H13F2NO2S/c1-22-12-5-6-14-11(7-12)9-15(20-14)16(21)10-3-2-4-13(8-10)23-17(18)19/h2-9,17,20H,1H3
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n/an/a 2.10E+3n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
Tubulin beta-2B chain


(Bos taurus)
BDBM50107661
PNG
((3,4-Dichloro-phenyl)-(5-methoxy-1H-indol-2-yl)-me...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C16H11Cl2NO2/c1-21-11-3-5-14-10(6-11)8-15(19-14)16(20)9-2-4-12(17)13(18)7-9/h2-8,19H,1H3
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n/an/a 2.50E+3n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
Tubulin beta-2B chain


(Bos taurus)
BDBM50107653
PNG
((2-Methoxy-phenyl)-(5-methyl-1H-indol-2-yl)-methan...)
Show SMILES COc1ccccc1C(=O)c1cc2cc(C)ccc2[nH]1
Show InChI InChI=1S/C17H15NO2/c1-11-7-8-14-12(9-11)10-15(18-14)17(19)13-5-3-4-6-16(13)20-2/h3-10,18H,1-2H3
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n/an/a 3.50E+3n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
Tubulin beta-2B chain


(Bos taurus)
BDBM50107652
PNG
((4-Bromo-phenyl)-(5-methoxy-1H-indol-2-yl)-methano...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)c1ccc(Br)cc1
Show InChI InChI=1S/C16H12BrNO2/c1-20-13-6-7-14-11(8-13)9-15(18-14)16(19)10-2-4-12(17)5-3-10/h2-9,18H,1H3
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n/an/a 4.30E+3n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
Tubulin beta-2B chain


(Bos taurus)
BDBM50107695
PNG
((5-Methoxy-1H-indol-2-yl)-o-tolyl-methanone | CHEM...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)c1ccccc1C
Show InChI InChI=1S/C17H15NO2/c1-11-5-3-4-6-14(11)17(19)16-10-12-9-13(20-2)7-8-15(12)18-16/h3-10,18H,1-2H3
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PubMed
n/an/a 4.80E+3n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
Tubulin beta-2B chain


(Bos taurus)
BDBM50107654
PNG
((4-Chloro-phenyl)-(5-methoxy-1H-indol-2-yl)-methan...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C16H12ClNO2/c1-20-13-6-7-14-11(8-13)9-15(18-14)16(19)10-2-4-12(17)5-3-10/h2-9,18H,1H3
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n/an/a 5.00E+3n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
Tubulin beta-2B chain


(Bos taurus)
BDBM50107667
PNG
((2,5-Dimethyl-phenyl)-(5-methoxy-1H-indol-2-yl)-me...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)c1cc(C)ccc1C
Show InChI InChI=1S/C18H17NO2/c1-11-4-5-12(2)15(8-11)18(20)17-10-13-9-14(21-3)6-7-16(13)19-17/h4-10,19H,1-3H3
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n/an/a 5.20E+3n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
Tubulin beta-2B chain


(Bos taurus)
BDBM50107691
PNG
((2,4-Dimethoxy-phenyl)-(5-methoxy-1H-indol-2-yl)-m...)
Show SMILES COc1ccc(C(=O)c2cc3cc(OC)ccc3[nH]2)c(OC)c1
Show InChI InChI=1S/C18H17NO4/c1-21-12-5-7-15-11(8-12)9-16(19-15)18(20)14-6-4-13(22-2)10-17(14)23-3/h4-10,19H,1-3H3
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n/an/a 5.60E+3n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
Tubulin beta-2B chain


(Bos taurus)
BDBM50107685
PNG
((2-Amino-phenyl)-(5-methoxy-1H-indol-2-yl)-methano...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)c1ccccc1N
Show InChI InChI=1S/C16H14N2O2/c1-20-11-6-7-14-10(8-11)9-15(18-14)16(19)12-4-2-3-5-13(12)17/h2-9,18H,17H2,1H3
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n/an/a 6.70E+3n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
Tubulin beta-2B chain


(Bos taurus)
BDBM50107683
PNG
((4-Ethyl-phenyl)-(5-methoxy-1H-indol-2-yl)-methano...)
Show SMILES CCc1ccc(cc1)C(=O)c1cc2cc(OC)ccc2[nH]1
Show InChI InChI=1S/C18H17NO2/c1-3-12-4-6-13(7-5-12)18(20)17-11-14-10-15(21-2)8-9-16(14)19-17/h4-11,19H,3H2,1-2H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
Tubulin beta-2B chain


(Bos taurus)
BDBM50107657
PNG
((2,3-Dimethoxy-phenyl)-(5-methoxy-1H-indol-2-yl)-m...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)c1cccc(OC)c1OC
Show InChI InChI=1S/C18H17NO4/c1-21-12-7-8-14-11(9-12)10-15(19-14)17(20)13-5-4-6-16(22-2)18(13)23-3/h4-10,19H,1-3H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
Tubulin beta-2B chain


(Bos taurus)
BDBM50107692
PNG
((3-Methoxy-phenyl)-(5-methyl-1H-indol-2-yl)-methan...)
Show SMILES COc1cccc(c1)C(=O)c1cc2cc(C)ccc2[nH]1
Show InChI InChI=1S/C17H15NO2/c1-11-6-7-15-13(8-11)10-16(18-15)17(19)12-4-3-5-14(9-12)20-2/h3-10,18H,1-2H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
Tubulin beta-2B chain


(Bos taurus)
BDBM50107689
PNG
((5-Methoxy-1H-indol-2-yl)-(2-nitro-phenyl)-methano...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)c1ccccc1[N+]([O-])=O
Show InChI InChI=1S/C16H12N2O4/c1-22-11-6-7-13-10(8-11)9-14(17-13)16(19)12-4-2-3-5-15(12)18(20)21/h2-9,17H,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
Tubulin beta-2B chain


(Bos taurus)
BDBM50107668
PNG
((1H-Indol-2-yl)-(2-methoxy-phenyl)-methanone | CHE...)
Show SMILES COc1ccccc1C(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C16H13NO2/c1-19-15-9-5-3-7-12(15)16(18)14-10-11-6-2-4-8-13(11)17-14/h2-10,17H,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
Tubulin beta-2B chain


(Bos taurus)
BDBM50107659
PNG
((5-Methoxy-1H-indol-2-yl)-(3-trifluoromethylsulfan...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)c1cccc(SC(F)(F)F)c1
Show InChI InChI=1S/C17H12F3NO2S/c1-23-12-5-6-14-11(7-12)9-15(21-14)16(22)10-3-2-4-13(8-10)24-17(18,19)20/h2-9,21H,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
Tubulin beta-2B chain


(Bos taurus)
BDBM50107660
PNG
((5-Methoxy-1H-indol-2-yl)-(2,3,4-trimethoxy-phenyl...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)c1ccc(OC)c(OC)c1OC
Show InChI InChI=1S/C19H19NO5/c1-22-12-5-7-14-11(9-12)10-15(20-14)17(21)13-6-8-16(23-2)19(25-4)18(13)24-3/h5-10,20H,1-4H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
Tubulin beta-2B chain


(Bos taurus)
BDBM50107665
PNG
((3-Amino-2-methyl-phenyl)-(5-methoxy-1H-indol-2-yl...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)c1cccc(N)c1C
Show InChI InChI=1S/C17H16N2O2/c1-10-13(4-3-5-14(10)18)17(20)16-9-11-8-12(21-2)6-7-15(11)19-16/h3-9,19H,18H2,1-2H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
Tubulin beta-2B chain


(Bos taurus)
BDBM50107688
PNG
((5-Methoxy-1H-indol-2-yl)-(3-methoxy-2-nitro-pheny...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)c1cccc(OC)c1[N+]([O-])=O
Show InChI InChI=1S/C17H14N2O5/c1-23-11-6-7-13-10(8-11)9-14(18-13)17(20)12-4-3-5-15(24-2)16(12)19(21)22/h3-9,18H,1-2H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
Tubulin beta-2B chain


(Bos taurus)
BDBM50107655
PNG
((5-Methoxy-1H-indol-2-yl)-(2-methyl-3-nitro-phenyl...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)c1cccc(c1C)[N+]([O-])=O
Show InChI InChI=1S/C17H14N2O4/c1-10-13(4-3-5-16(10)19(21)22)17(20)15-9-11-8-12(23-2)6-7-14(11)18-15/h3-9,18H,1-2H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
Tubulin beta-2B chain


(Bos taurus)
BDBM50107669
PNG
((2-Chloro-6-fluoro-phenyl)-(5-methoxy-1H-indol-2-y...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)c1c(F)cccc1Cl
Show InChI InChI=1S/C16H11ClFNO2/c1-21-10-5-6-13-9(7-10)8-14(19-13)16(20)15-11(17)3-2-4-12(15)18/h2-8,19H,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
Tubulin beta-2B chain


(Bos taurus)
BDBM50107666
PNG
((5-Methoxy-1H-indol-2-yl)-(4-propyl-phenyl)-methan...)
Show SMILES CCCc1ccc(cc1)C(=O)c1cc2cc(OC)ccc2[nH]1
Show InChI InChI=1S/C19H19NO2/c1-3-4-13-5-7-14(8-6-13)19(21)18-12-15-11-16(22-2)9-10-17(15)20-18/h5-12,20H,3-4H2,1-2H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.


J Med Chem 44: 4535-53 (2001)


BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%