Affinity Data by PubMed id=11844685

PubMed code 11844685

Found 20 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50109929 (7-({2-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-eth...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Tested for the binding constant against cloned human Dopamine receptor D3 in HEK cells by displacing [3H]-spiperone				Bioorg Med Chem Lett 12: 619-22 (2002) BindingDB Entry DOI: 10.7270/Q25X287P
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50109931 ((+)-7-{[4-(4-phenylpiperazin-1-yl)butyl]prop-2-yny...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Tested for the binding constant against cloned human Dopamine receptor D3 in HEK cells by displacing [3H]-spiperone				Bioorg Med Chem Lett 12: 619-22 (2002) BindingDB Entry DOI: 10.7270/Q25X287P
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50109926 (7-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Tested for the binding constant against cloned human Dopamine receptor D3 in HEK cells by displacing [3H]-spiperone				Bioorg Med Chem Lett 12: 619-22 (2002) BindingDB Entry DOI: 10.7270/Q25X287P
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50109930 (7-({4-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-but...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Tested for the binding constant against cloned human Dopamine receptor D3 in HEK cells by displacing [3H]-spiperone				Bioorg Med Chem Lett 12: 619-22 (2002) BindingDB Entry DOI: 10.7270/Q25X287P
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50109925 (7-({4-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-but...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Tested for the binding constant against cloned human Dopamine receptor D3 in HEK cells by displacing [3H]-spiperone				Bioorg Med Chem Lett 12: 619-22 (2002) BindingDB Entry DOI: 10.7270/Q25X287P
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50109927 ((+)-7-[(4-(4-phenylpiperazin-1-yl)butyl)(propyl)am...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Tested for the binding constant against cloned human Dopamine receptor D3 in HEK cells by displacing [3H]-spiperone				Bioorg Med Chem Lett 12: 619-22 (2002) BindingDB Entry DOI: 10.7270/Q25X287P
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50109925 (7-({4-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-but...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Tested for the binding constant against cloned human Dopamine receptor D2L in HEK cells by displacing [3H]-spiperone				Bioorg Med Chem Lett 12: 619-22 (2002) BindingDB Entry DOI: 10.7270/Q25X287P
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50109930 (7-({4-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-but...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Tested for the binding constant against cloned human Dopamine receptor D2L in HEK cells by displacing [3H]-spiperone				Bioorg Med Chem Lett 12: 619-22 (2002) BindingDB Entry DOI: 10.7270/Q25X287P
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50109928 (7-{[2-(4-Phenyl-piperazin-1-yl)-ethyl]-prop-2-ynyl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Tested for the binding constant against cloned human Dopamine receptor D3 in HEK cells by displacing [3H]-spiperone				Bioorg Med Chem Lett 12: 619-22 (2002) BindingDB Entry DOI: 10.7270/Q25X287P
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50109929 (7-({2-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-eth...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Tested for the binding constant against cloned human Dopamine receptor D2L in HEK cells by displacing [3H]-spiperone				Bioorg Med Chem Lett 12: 619-22 (2002) BindingDB Entry DOI: 10.7270/Q25X287P
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50109923 (4-{(7-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Tested for the binding constant against cloned human Dopamine receptor D3 in HEK cells by displacing [3H]-spiperone				Bioorg Med Chem Lett 12: 619-22 (2002) BindingDB Entry DOI: 10.7270/Q25X287P
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50109922 (CHEMBL422883 \| N-(2-{(7-Hydroxy-1,2,3,4-tetrahydro...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Tested for the binding constant against cloned human Dopamine receptor D3 in HEK cells by displacing [3H]-spiperone				Bioorg Med Chem Lett 12: 619-22 (2002) BindingDB Entry DOI: 10.7270/Q25X287P
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50109931 ((+)-7-{[4-(4-phenylpiperazin-1-yl)butyl]prop-2-yny...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	68	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Tested for the binding constant against cloned human Dopamine receptor D2L in HEK cells by displacing [3H]-spiperone				Bioorg Med Chem Lett 12: 619-22 (2002) BindingDB Entry DOI: 10.7270/Q25X287P
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50109927 ((+)-7-[(4-(4-phenylpiperazin-1-yl)butyl)(propyl)am...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	114	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Tested for the binding constant against cloned human Dopamine receptor D2L in HEK cells by displacing [3H]-spiperone				Bioorg Med Chem Lett 12: 619-22 (2002) BindingDB Entry DOI: 10.7270/Q25X287P
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50109926 (7-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	213	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Tested for the binding constant against cloned human Dopamine receptor D2L in HEK cells by displacing [3H]-spiperone				Bioorg Med Chem Lett 12: 619-22 (2002) BindingDB Entry DOI: 10.7270/Q25X287P
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50109928 (7-{[2-(4-Phenyl-piperazin-1-yl)-ethyl]-prop-2-ynyl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	245	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Tested for the binding constant against cloned human Dopamine receptor D2L in HEK cells by displacing [3H]-spiperone				Bioorg Med Chem Lett 12: 619-22 (2002) BindingDB Entry DOI: 10.7270/Q25X287P
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50109922 (CHEMBL422883 \| N-(2-{(7-Hydroxy-1,2,3,4-tetrahydro...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	354	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Tested for the binding constant against cloned human Dopamine receptor D2L in HEK cells by displacing [3H]-spiperone				Bioorg Med Chem Lett 12: 619-22 (2002) BindingDB Entry DOI: 10.7270/Q25X287P
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50109923 (4-{(7-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	622	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Tested for the binding constant against cloned human Dopamine receptor D2L in HEK cells by displacing [3H]-spiperone				Bioorg Med Chem Lett 12: 619-22 (2002) BindingDB Entry DOI: 10.7270/Q25X287P
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50109924 (CHEMBL156816 \| N-(4-{(7-Hydroxy-1,2,3,4-tetrahydro...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	756	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Tested for the binding constant against cloned human Dopamine receptor D3 in HEK cells by displacing [3H]-spiperone				Bioorg Med Chem Lett 12: 619-22 (2002) BindingDB Entry DOI: 10.7270/Q25X287P
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50109924 (CHEMBL156816 \| N-(4-{(7-Hydroxy-1,2,3,4-tetrahydro...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	782	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Tested for the binding constant against cloned human Dopamine receptor D2L in HEK cells by displacing [3H]-spiperone				Bioorg Med Chem Lett 12: 619-22 (2002) BindingDB Entry DOI: 10.7270/Q25X287P
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%