BindingDB logo
myBDB logout

PubMed code 12161118

Compile data set for download or QSAR
Found 28 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nitric oxide synthase, inducible


(Mus musculus (mouse))
BDBM50116666
PNG
(4-Methyl-3,6-dihydro-1H-pyridin-(2Z)-ylideneamine ...)
Show SMILES CC1=CC(N)=NCC1 |c:4,t:1|
Show InChI InChI=1S/C6H10N2/c1-5-2-3-8-6(7)4-5/h4H,2-3H2,1H3,(H2,7,8)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 22n/an/an/an/an/an/a



Fukui Research Institute

Curated by ChEMBL


Assay Description
The concentration required for inhibition of Inducible nitric oxide synthase in mouse


Bioorg Med Chem Lett 12: 2291-4 (2002)


BindingDB Entry DOI: 10.7270/Q2M32V3P
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Mus musculus (mouse))
BDBM50116674
PNG
(6-Allyl-4-methyl-5,6-dihydro-1H-pyridin-(2Z)-ylide...)
Show SMILES CC1=CC(N)=NC(CC=C)C1 |c:4,t:1|
Show InChI InChI=1S/C9H14N2/c1-3-4-8-5-7(2)6-9(10)11-8/h3,6,8H,1,4-5H2,2H3,(H2,10,11)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 25n/an/an/an/an/an/a



Fukui Research Institute

Curated by ChEMBL


Assay Description
The concentration required for inhibition of Inducible nitric oxide synthase in mouse


Bioorg Med Chem Lett 12: 2291-4 (2002)


BindingDB Entry DOI: 10.7270/Q2M32V3P
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))
BDBM50116674
PNG
(6-Allyl-4-methyl-5,6-dihydro-1H-pyridin-(2Z)-ylide...)
Show SMILES CC1=CC(N)=NC(CC=C)C1 |c:4,t:1|
Show InChI InChI=1S/C9H14N2/c1-3-4-8-5-7(2)6-9(10)11-8/h3,6,8H,1,4-5H2,2H3,(H2,10,11)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 50n/an/an/an/an/an/a



Fukui Research Institute

Curated by ChEMBL


Assay Description
Concentration required to inhibit human Inducible nitric oxide synthase over expressed in A549 cells


Bioorg Med Chem Lett 12: 2291-4 (2002)


BindingDB Entry DOI: 10.7270/Q2M32V3P
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))
BDBM50116668
PNG
(4-Methyl-6-propyl-5,6-dihydro-1H-pyridin-(2Z)-ylid...)
Show SMILES CCCC1CC(C)=CC(N)=N1 |c:6,9|
Show InChI InChI=1S/C9H16N2/c1-3-4-8-5-7(2)6-9(10)11-8/h6,8H,3-5H2,1-2H3,(H2,10,11)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 60n/an/an/an/an/an/a



Fukui Research Institute

Curated by ChEMBL


Assay Description
Concentration required to inhibit human Inducible nitric oxide synthase over expressed in A549 cells


Bioorg Med Chem Lett 12: 2291-4 (2002)


BindingDB Entry DOI: 10.7270/Q2M32V3P
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Mus musculus (mouse))
BDBM50116667
PNG
(4,5,5-Trimethyl-5,6-dihydro-1H-pyridin-(2Z)-yliden...)
Show SMILES CC1=CC(N)=NCC1(C)C |c:4,t:1|
Show InChI InChI=1S/C8H14N2/c1-6-4-7(9)10-5-8(6,2)3/h4H,5H2,1-3H3,(H2,9,10)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 100n/an/an/an/an/an/a



Fukui Research Institute

Curated by ChEMBL


Assay Description
The concentration required for inhibition of Inducible nitric oxide synthase in mouse


Bioorg Med Chem Lett 12: 2291-4 (2002)


BindingDB Entry DOI: 10.7270/Q2M32V3P
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Mus musculus (mouse))
BDBM50116668
PNG
(4-Methyl-6-propyl-5,6-dihydro-1H-pyridin-(2Z)-ylid...)
Show SMILES CCCC1CC(C)=CC(N)=N1 |c:6,9|
Show InChI InChI=1S/C9H16N2/c1-3-4-8-5-7(2)6-9(10)11-8/h6,8H,3-5H2,1-2H3,(H2,10,11)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 100n/an/an/an/an/an/a



Fukui Research Institute

Curated by ChEMBL


Assay Description
The concentration required for inhibition of Inducible nitric oxide synthase in mouse


Bioorg Med Chem Lett 12: 2291-4 (2002)


BindingDB Entry DOI: 10.7270/Q2M32V3P
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))
BDBM50116670
PNG
((4aR,7aR)-4-Methyl-1,4a,5,6,7,7a-hexahydro-[1]pyri...)
Show SMILES CC1=CC(N)=N[C@@H]2CCC[C@H]12 |c:4,t:1|
Show InChI InChI=1S/C9H14N2/c1-6-5-9(10)11-8-4-2-3-7(6)8/h5,7-8H,2-4H2,1H3,(H2,10,11)/t7-,8-/m1/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 170n/an/an/an/an/an/a



Fukui Research Institute

Curated by ChEMBL


Assay Description
Concentration required to inhibit human Inducible nitric oxide synthase over expressed in A549 cells


Bioorg Med Chem Lett 12: 2291-4 (2002)


BindingDB Entry DOI: 10.7270/Q2M32V3P
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))
BDBM50116676
PNG
(4,6-Dimethyl-5,6-dihydro-1H-pyridin-(2Z)-ylideneam...)
Show SMILES CC1CC(C)=CC(N)=N1 |c:4,7|
Show InChI InChI=1S/C7H12N2/c1-5-3-6(2)9-7(8)4-5/h4,6H,3H2,1-2H3,(H2,8,9)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 180n/an/an/an/an/an/a



Fukui Research Institute

Curated by ChEMBL


Assay Description
Concentration required to inhibit Inducible nitric oxide synthase over expressed in A549 cells


Bioorg Med Chem Lett 12: 2291-4 (2002)


BindingDB Entry DOI: 10.7270/Q2M32V3P
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))
BDBM50116666
PNG
(4-Methyl-3,6-dihydro-1H-pyridin-(2Z)-ylideneamine ...)
Show SMILES CC1=CC(N)=NCC1 |c:4,t:1|
Show InChI InChI=1S/C6H10N2/c1-5-2-3-8-6(7)4-5/h4H,2-3H2,1H3,(H2,7,8)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 200n/an/an/an/an/an/a



Fukui Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human endothelial Nitric Oxide Synthase expressed in Sf-21 cells


Bioorg Med Chem Lett 12: 2291-4 (2002)


BindingDB Entry DOI: 10.7270/Q2M32V3P
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))
BDBM50116666
PNG
(4-Methyl-3,6-dihydro-1H-pyridin-(2Z)-ylideneamine ...)
Show SMILES CC1=CC(N)=NCC1 |c:4,t:1|
Show InChI InChI=1S/C6H10N2/c1-5-2-3-8-6(7)4-5/h4H,2-3H2,1H3,(H2,7,8)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 230n/an/an/an/an/an/a



Fukui Research Institute

Curated by ChEMBL


Assay Description
Concentration required to inhibit human Inducible nitric oxide synthase over expressed in A549 cells


Bioorg Med Chem Lett 12: 2291-4 (2002)


BindingDB Entry DOI: 10.7270/Q2M32V3P
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))
BDBM50116676
PNG
(4,6-Dimethyl-5,6-dihydro-1H-pyridin-(2Z)-ylideneam...)
Show SMILES CC1CC(C)=CC(N)=N1 |c:4,7|
Show InChI InChI=1S/C7H12N2/c1-5-3-6(2)9-7(8)4-5/h4,6H,3H2,1-2H3,(H2,8,9)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 240n/an/an/an/an/an/a



Fukui Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human endothelial Nitric Oxide Synthase expressed in Sf-21 cells


Bioorg Med Chem Lett 12: 2291-4 (2002)


BindingDB Entry DOI: 10.7270/Q2M32V3P
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))
BDBM50116673
PNG
(3,4-Dimethyl-5,6-dihydro-1H-pyridin-(2Z)-ylideneam...)
Show SMILES CC1=C(C)C(N)=NCC1 |c:1,5|
Show InChI InChI=1S/C7H12N2/c1-5-3-4-9-7(8)6(5)2/h3-4H2,1-2H3,(H2,8,9)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 310n/an/an/an/an/an/a



Fukui Research Institute

Curated by ChEMBL


Assay Description
Concentration required to inhibit human Inducible nitric oxide synthase over expressed in A549 cells


Bioorg Med Chem Lett 12: 2291-4 (2002)


BindingDB Entry DOI: 10.7270/Q2M32V3P
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))
BDBM50116673
PNG
(3,4-Dimethyl-5,6-dihydro-1H-pyridin-(2Z)-ylideneam...)
Show SMILES CC1=C(C)C(N)=NCC1 |c:1,5|
Show InChI InChI=1S/C7H12N2/c1-5-3-4-9-7(8)6(5)2/h3-4H2,1-2H3,(H2,8,9)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 320n/an/an/an/an/an/a



Fukui Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human endothelial Nitric Oxide Synthase expressed in Sf-21 cells


Bioorg Med Chem Lett 12: 2291-4 (2002)


BindingDB Entry DOI: 10.7270/Q2M32V3P
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))
BDBM50116674
PNG
(6-Allyl-4-methyl-5,6-dihydro-1H-pyridin-(2Z)-ylide...)
Show SMILES CC1=CC(N)=NC(CC=C)C1 |c:4,t:1|
Show InChI InChI=1S/C9H14N2/c1-3-4-8-5-7(2)6-9(10)11-8/h3,6,8H,1,4-5H2,2H3,(H2,10,11)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 360n/an/an/an/an/an/a



Fukui Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human endothelial Nitric Oxide Synthase expressed in Sf-21 cells


Bioorg Med Chem Lett 12: 2291-4 (2002)


BindingDB Entry DOI: 10.7270/Q2M32V3P
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))
BDBM50116667
PNG
(4,5,5-Trimethyl-5,6-dihydro-1H-pyridin-(2Z)-yliden...)
Show SMILES CC1=CC(N)=NCC1(C)C |c:4,t:1|
Show InChI InChI=1S/C8H14N2/c1-6-4-7(9)10-5-8(6,2)3/h4H,5H2,1-3H3,(H2,9,10)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 420n/an/an/an/an/an/a



Fukui Research Institute

Curated by ChEMBL


Assay Description
Concentration required to inhibit human Inducible nitric oxide synthase over expressed in A549 cells


Bioorg Med Chem Lett 12: 2291-4 (2002)


BindingDB Entry DOI: 10.7270/Q2M32V3P
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))
BDBM50116666
PNG
(4-Methyl-3,6-dihydro-1H-pyridin-(2Z)-ylideneamine ...)
Show SMILES CC1=CC(N)=NCC1 |c:4,t:1|
Show InChI InChI=1S/C6H10N2/c1-5-2-3-8-6(7)4-5/h4H,2-3H2,1H3,(H2,7,8)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 440n/an/an/an/an/an/a



Fukui Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human endothelial Nitric Oxide Synthase expressed in Sf-21 cells


Bioorg Med Chem Lett 12: 2291-4 (2002)


BindingDB Entry DOI: 10.7270/Q2M32V3P
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))
BDBM50116675
PNG
(4,5-Dimethyl-5,6-dihydro-1H-pyridin-(2Z)-ylideneam...)
Show SMILES CC1CN=C(N)C=C1C |c:6,t:3|
Show InChI InChI=1S/C7H12N2/c1-5-3-7(8)9-4-6(5)2/h3,6H,4H2,1-2H3,(H2,8,9)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 510n/an/an/an/an/an/a



Fukui Research Institute

Curated by ChEMBL


Assay Description
Concentration required to inhibit Inducible nitric oxide synthase over expressed in A549 cells


Bioorg Med Chem Lett 12: 2291-4 (2002)


BindingDB Entry DOI: 10.7270/Q2M32V3P
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))
BDBM50116670
PNG
((4aR,7aR)-4-Methyl-1,4a,5,6,7,7a-hexahydro-[1]pyri...)
Show SMILES CC1=CC(N)=N[C@@H]2CCC[C@H]12 |c:4,t:1|
Show InChI InChI=1S/C9H14N2/c1-6-5-9(10)11-8-4-2-3-7(6)8/h5,7-8H,2-4H2,1H3,(H2,10,11)/t7-,8-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 510n/an/an/an/an/an/a



Fukui Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human endothelial Nitric Oxide Synthase expressed in Sf-21 cells


Bioorg Med Chem Lett 12: 2291-4 (2002)


BindingDB Entry DOI: 10.7270/Q2M32V3P
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))
BDBM50116675
PNG
(4,5-Dimethyl-5,6-dihydro-1H-pyridin-(2Z)-ylideneam...)
Show SMILES CC1CN=C(N)C=C1C |c:6,t:3|
Show InChI InChI=1S/C7H12N2/c1-5-3-7(8)9-4-6(5)2/h3,6H,4H2,1-2H3,(H2,8,9)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 520n/an/an/an/an/an/a



Fukui Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human endothelial Nitric Oxide Synthase expressed in Sf-21 cells


Bioorg Med Chem Lett 12: 2291-4 (2002)


BindingDB Entry DOI: 10.7270/Q2M32V3P
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))
BDBM50116668
PNG
(4-Methyl-6-propyl-5,6-dihydro-1H-pyridin-(2Z)-ylid...)
Show SMILES CCCC1CC(C)=CC(N)=N1 |c:6,9|
Show InChI InChI=1S/C9H16N2/c1-3-4-8-5-7(2)6-9(10)11-8/h6,8H,3-5H2,1-2H3,(H2,10,11)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 580n/an/an/an/an/an/a



Fukui Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human endothelial Nitric Oxide Synthase expressed in Sf-21 cells


Bioorg Med Chem Lett 12: 2291-4 (2002)


BindingDB Entry DOI: 10.7270/Q2M32V3P
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))
BDBM50116666
PNG
(4-Methyl-3,6-dihydro-1H-pyridin-(2Z)-ylideneamine ...)
Show SMILES CC1=CC(N)=NCC1 |c:4,t:1|
Show InChI InChI=1S/C6H10N2/c1-5-2-3-8-6(7)4-5/h4H,2-3H2,1H3,(H2,7,8)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 700n/an/an/an/an/an/a



Fukui Research Institute

Curated by ChEMBL


Assay Description
Concentration required to inhibit human Inducible nitric oxide synthase over expressed in A549 cells


Bioorg Med Chem Lett 12: 2291-4 (2002)


BindingDB Entry DOI: 10.7270/Q2M32V3P
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))
BDBM50237936
PNG
(4-Ethyl-5,6-dihydro-1H-pyridin-(2Z)-ylideneamine |...)
Show SMILES CCC1=CC(N)=NCC1 |c:5,t:2|
Show InChI InChI=1S/C7H12N2/c1-2-6-3-4-9-7(8)5-6/h5H,2-4H2,1H3,(H2,8,9)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 1.20E+3n/an/an/an/an/an/a



Fukui Research Institute

Curated by ChEMBL


Assay Description
Concentration required to inhibit human Inducible nitric oxide synthase over expressed in A549 cells


Bioorg Med Chem Lett 12: 2291-4 (2002)


BindingDB Entry DOI: 10.7270/Q2M32V3P
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))
BDBM50116677
PNG
((4aR,8aR)-4-Methyl-4a,5,6,7,8,8a-hexahydro-1H-quin...)
Show SMILES CC1=CC(N)=N[C@@H]2CCCC[C@H]12 |c:4,t:1|
Show InChI InChI=1S/C10H16N2/c1-7-6-10(11)12-9-5-3-2-4-8(7)9/h6,8-9H,2-5H2,1H3,(H2,11,12)/t8-,9-/m1/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 1.40E+3n/an/an/an/an/an/a



Fukui Research Institute

Curated by ChEMBL


Assay Description
Concentration required to inhibit human Inducible nitric oxide synthase over expressed in A549 cells


Bioorg Med Chem Lett 12: 2291-4 (2002)


BindingDB Entry DOI: 10.7270/Q2M32V3P
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))
BDBM50237936
PNG
(4-Ethyl-5,6-dihydro-1H-pyridin-(2Z)-ylideneamine |...)
Show SMILES CCC1=CC(N)=NCC1 |c:5,t:2|
Show InChI InChI=1S/C7H12N2/c1-2-6-3-4-9-7(8)5-6/h5H,2-4H2,1H3,(H2,8,9)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



Fukui Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human endothelial Nitric Oxide Synthase expressed in Sf-21 cells


Bioorg Med Chem Lett 12: 2291-4 (2002)


BindingDB Entry DOI: 10.7270/Q2M32V3P
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))
BDBM50116667
PNG
(4,5,5-Trimethyl-5,6-dihydro-1H-pyridin-(2Z)-yliden...)
Show SMILES CC1=CC(N)=NCC1(C)C |c:4,t:1|
Show InChI InChI=1S/C8H14N2/c1-6-4-7(9)10-5-8(6,2)3/h4H,5H2,1-3H3,(H2,9,10)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 2.10E+3n/an/an/an/an/an/a



Fukui Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human endothelial Nitric Oxide Synthase expressed in Sf-21 cells


Bioorg Med Chem Lett 12: 2291-4 (2002)


BindingDB Entry DOI: 10.7270/Q2M32V3P
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))
BDBM50116669
PNG
(5,5-Dimethyl-5,6-dihydro-1H-pyridin-(2Z)-ylideneam...)
Show SMILES CC1(C)CN=C(N)C=C1 |c:7,t:4|
Show InChI InChI=1S/C7H12N2/c1-7(2)4-3-6(8)9-5-7/h3-4H,5H2,1-2H3,(H2,8,9)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 2.80E+3n/an/an/an/an/an/a



Fukui Research Institute

Curated by ChEMBL


Assay Description
Concentration required to inhibit human Inducible nitric oxide synthase over expressed in A549 cells


Bioorg Med Chem Lett 12: 2291-4 (2002)


BindingDB Entry DOI: 10.7270/Q2M32V3P
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))
BDBM50116677
PNG
((4aR,8aR)-4-Methyl-4a,5,6,7,8,8a-hexahydro-1H-quin...)
Show SMILES CC1=CC(N)=N[C@@H]2CCCC[C@H]12 |c:4,t:1|
Show InChI InChI=1S/C10H16N2/c1-7-6-10(11)12-9-5-3-2-4-8(7)9/h6,8-9H,2-5H2,1H3,(H2,11,12)/t8-,9-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 7.40E+3n/an/an/an/an/an/a



Fukui Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human endothelial Nitric Oxide Synthase expressed in Sf-21 cells


Bioorg Med Chem Lett 12: 2291-4 (2002)


BindingDB Entry DOI: 10.7270/Q2M32V3P
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))
BDBM50116669
PNG
(5,5-Dimethyl-5,6-dihydro-1H-pyridin-(2Z)-ylideneam...)
Show SMILES CC1(C)CN=C(N)C=C1 |c:7,t:4|
Show InChI InChI=1S/C7H12N2/c1-7(2)4-3-6(8)9-5-7/h3-4H,5H2,1-2H3,(H2,8,9)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 3.10E+4n/an/an/an/an/an/a



Fukui Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human endothelial Nitric Oxide Synthase expressed in Sf-21 cells


Bioorg Med Chem Lett 12: 2291-4 (2002)


BindingDB Entry DOI: 10.7270/Q2M32V3P
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%