Affinity Data by PubMed id=12213077

PubMed code 12213077

Found 18 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Escherichia coli)	BDBM50074938 ((R)-2-(4-Methoxy-phenyl)-4,5-dihydro-oxazole-4-car...) Show SMILES COc1ccc(cc1)C1=N[C@H](CO1)C(=O)NO \|t:9\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Duke University Curated by ChEMBL					Assay Description Inhibition of E. coli LpxC(UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase.				J Med Chem 45: 4359-70 (2002) BindingDB Entry DOI: 10.7270/Q2W66K3D
Duke University Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Escherichia coli)	BDBM50118596 ((R/S)-[3-(4-Methoxy-phenyl)-4,5-dihydro-isoxazol-5...) Show SMILES COc1ccc(cc1)-c1cc(on1)P(O)(O)O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Duke University Curated by ChEMBL					Assay Description Inhibition of E. coli LpxC(UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase.				J Med Chem 45: 4359-70 (2002) BindingDB Entry DOI: 10.7270/Q2W66K3D
Duke University Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Escherichia coli)	BDBM50409600 (CHEMBL2111931) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.37E+3	n/a	n/a	n/a	n/a	n/a	n/a
Duke University Curated by ChEMBL					Assay Description Inhibition of E. coli LpxC(UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase.				J Med Chem 45: 4359-70 (2002) BindingDB Entry DOI: 10.7270/Q2W66K3D
Duke University Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Escherichia coli)	BDBM50118597 ((R/S)-Thioacetic acid S-{2-[3-(4-methoxy-phenyl)-4...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Duke University Curated by ChEMBL					Assay Description Inhibition of E. coli LpxC(UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase.				J Med Chem 45: 4359-70 (2002) BindingDB Entry DOI: 10.7270/Q2W66K3D
Duke University Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Escherichia coli)	BDBM50118582 ((R)3-(4-Methoxy-phenyl)-4,5-dihydro-isoxazole-5-ca...) Show SMILES COc1ccc(cc1)C1=NOC(C1)C(=O)NO \|t:9\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Duke University Curated by ChEMBL					Assay Description Inhibition of E. coli LpxC(UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase.				J Med Chem 45: 4359-70 (2002) BindingDB Entry DOI: 10.7270/Q2W66K3D
Duke University Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Escherichia coli)	BDBM50118590 ((R/S)-[3-(4-Methoxy-phenyl)-4,5-dihydro-isoxazol-5...) Show SMILES COc1ccc(cc1)C1=NOC(CS)C1 \|t:9\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Duke University Curated by ChEMBL					Assay Description Inhibition of E. coli LpxC(UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase.				J Med Chem 45: 4359-70 (2002) BindingDB Entry DOI: 10.7270/Q2W66K3D
Duke University Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Escherichia coli)	BDBM50118594 ((R/S)-2-Mercapto-1-[3-(4-methoxy-phenyl)-4,5-dihyd...) Show SMILES COc1ccc(cc1)C1=NOC(C1)C(=O)CS \|t:9\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Duke University Curated by ChEMBL					Assay Description Inhibition of E. coli LpxC(UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase.				J Med Chem 45: 4359-70 (2002) BindingDB Entry DOI: 10.7270/Q2W66K3D
Duke University Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Escherichia coli)	BDBM50118584 ((R/S)-[3-(4-Methoxy-phenyl)-4,5-dihydro-isoxazol-5...) Show SMILES COc1ccc(cc1)-c1cc(on1)P(C)(O)O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.70E+5	n/a	n/a	n/a	n/a	n/a	n/a
Duke University Curated by ChEMBL					Assay Description Inhibition of E. coli LpxC(UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase.				J Med Chem 45: 4359-70 (2002) BindingDB Entry DOI: 10.7270/Q2W66K3D
Duke University Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Escherichia coli)	BDBM50118581 ((R/S)-3-(4-Methoxy-phenyl)-4,5-dihydro-isoxazole-5...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>3.36E+5	n/a	n/a	n/a	n/a	n/a	n/a
Duke University Curated by ChEMBL					Assay Description Inhibition of E. coli LpxC(UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase.				J Med Chem 45: 4359-70 (2002) BindingDB Entry DOI: 10.7270/Q2W66K3D
Duke University Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Escherichia coli)	BDBM50118587 ((R/S)-3-(4-Methoxy-phenyl)-4,5-dihydro-isoxazole-5...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>3.92E+5	n/a	n/a	n/a	n/a	n/a	n/a
Duke University Curated by ChEMBL					Assay Description Inhibition of E. coli LpxC(UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase.				J Med Chem 45: 4359-70 (2002) BindingDB Entry DOI: 10.7270/Q2W66K3D
Duke University Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Escherichia coli)	BDBM50118595 ((R/S)-5-Methanesulfonyl-3-(4-methoxy-phenyl)-4,5-d...) Show SMILES COc1ccc(cc1)C1=NOC(C1)S(C)(=O)=O \|t:9\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>3.92E+5	n/a	n/a	n/a	n/a	n/a	n/a
Duke University Curated by ChEMBL					Assay Description Inhibition of E. coli LpxC(UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase.				J Med Chem 45: 4359-70 (2002) BindingDB Entry DOI: 10.7270/Q2W66K3D
Duke University Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Escherichia coli)	BDBM50118593 ((R,R)2-Mercapto-1-[3-(4-methoxy-phenyl)-4,5-dihy...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Duke University Curated by ChEMBL					Assay Description Inhibition of E. coli LpxC(UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase.				J Med Chem 45: 4359-70 (2002) BindingDB Entry DOI: 10.7270/Q2W66K3D
Duke University Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Escherichia coli)	BDBM50118586 ((R,S)-2-Mercapto-1-[3-(4-methoxy-phenyl)-4,5-dih...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Duke University Curated by ChEMBL					Assay Description Inhibition of E. coli LpxC(UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase.				J Med Chem 45: 4359-70 (2002) BindingDB Entry DOI: 10.7270/Q2W66K3D
Duke University Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Escherichia coli)	BDBM50118585 ((R/S)-3-(4-Methoxy-phenyl)-4,5-dihydro-isoxazole-5...) Show SMILES COc1ccc(cc1)C1=NOC(C1)C(=O)NNC=O \|t:9\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Duke University Curated by ChEMBL					Assay Description Inhibition of E. coli LpxC(UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase.				J Med Chem 45: 4359-70 (2002) BindingDB Entry DOI: 10.7270/Q2W66K3D
Duke University Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Escherichia coli)	BDBM50118583 ((R/S)-3-(4-Methoxy-phenyl)-4,5-dihydro-isoxazole-5...) Show SMILES COc1ccc(cc1)C1=NOC(C1)C(=O)NCO \|t:9\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Duke University Curated by ChEMBL					Assay Description Inhibition of E. coli LpxC(UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase.				J Med Chem 45: 4359-70 (2002) BindingDB Entry DOI: 10.7270/Q2W66K3D
Duke University Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Escherichia coli)	BDBM50118592 ((R/S)-3-(4-Methoxy-phenyl)-4,5-dihydro-isoxazole-5...) Show SMILES COc1ccc(cc1)C1=NOC(C1)C(=O)NN \|t:9\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>4.25E+5	n/a	n/a	n/a	n/a	n/a	n/a
Duke University Curated by ChEMBL					Assay Description Inhibition of E. coli LpxC(UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase.				J Med Chem 45: 4359-70 (2002) BindingDB Entry DOI: 10.7270/Q2W66K3D
Duke University Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Escherichia coli)	BDBM50118591 ((R/S)-3-(4-Methoxy-phenyl)-4,5-dihydro-isoxazole-5...) Show SMILES COc1ccc(cc1)C1=NOC(C1)C(O)=O \|t:9\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>4.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Duke University Curated by ChEMBL					Assay Description Inhibition of E. coli LpxC(UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase.				J Med Chem 45: 4359-70 (2002) BindingDB Entry DOI: 10.7270/Q2W66K3D
Duke University Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Escherichia coli)	BDBM50118580 ((R/S)-3-(4-Methoxy-phenyl)-4,5-dihydro-isoxazole-5...) Show SMILES COc1ccc(cc1)C1=NOC(C1)S(N)(=O)=O \|t:9\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.20E+6	n/a	n/a	n/a	n/a	n/a	n/a
Duke University Curated by ChEMBL					Assay Description Inhibition of E. coli LpxC(UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase.				J Med Chem 45: 4359-70 (2002) BindingDB Entry DOI: 10.7270/Q2W66K3D
Duke University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%