Affinity Data by PubMed id=12270163

PubMed code 12270163

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Aromatase (Homo sapiens (Human))	BDBM50118965 (4-Imidazol-1-yl-2-phenyl-chroman-7-ol \| CHEMBL9591...) Show SMILES Oc1ccc2C(CC(Oc2c1)c1ccccc1)n1ccnc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
UPRES EA 1085 Curated by ChEMBL					Assay Description Inhibition of aromatase activity in human placental microsomes				Bioorg Med Chem Lett 12: 2859-61 (2002) BindingDB Entry DOI: 10.7270/Q2PK0FHS
UPRES EA 1085 Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50118966 (1-(7-Methoxy-2-phenyl-chroman-4-yl)-1H-imidazole \|...) Show SMILES COc1ccc2C(CC(Oc2c1)c1ccccc1)n1ccnc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
UPRES EA 1085 Curated by ChEMBL					Assay Description Inhibition of aromatase activity in human placental microsomes				Bioorg Med Chem Lett 12: 2859-61 (2002) BindingDB Entry DOI: 10.7270/Q2PK0FHS
UPRES EA 1085 Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50104887 (2,3-dihydro-7-hydroxy-2-phenyl-4H-1-benzopyran-4-o...) Show SMILES Oc1ccc2C(=O)CC(Oc2c1)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
UPRES EA 1085 Curated by ChEMBL					Assay Description Inhibition of aromatase activity in human placental microsomes				Bioorg Med Chem Lett 12: 2859-61 (2002) BindingDB Entry DOI: 10.7270/Q2PK0FHS
UPRES EA 1085 Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9460 (3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione \| 3...) Show SMILES CCC1(CCC(=O)NC1=O)c1ccc(N)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
UPRES EA 1085 Curated by ChEMBL					Assay Description Inhibition of aromatase activity in human placental microsomes				Bioorg Med Chem Lett 12: 2859-61 (2002) BindingDB Entry DOI: 10.7270/Q2PK0FHS
UPRES EA 1085 Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50106920 ((+/-)-7-methoxy-2-phenylchroman-4-one \| 7-Methoxy-...) Show SMILES COc1ccc2C(=O)CC(Oc2c1)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
UPRES EA 1085 Curated by ChEMBL					Assay Description Inhibition of aromatase activity in human placental microsomes				Bioorg Med Chem Lett 12: 2859-61 (2002) BindingDB Entry DOI: 10.7270/Q2PK0FHS
UPRES EA 1085 Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%