Found 27 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50116538
(3-{[3-(4-Benzyl-phenoxy)-propyl]-methyl-amino}-pro...)Show InChI InChI=1S/C20H25NO3/c1-21(14-12-20(22)23)13-5-15-24-19-10-8-18(9-11-19)16-17-6-3-2-4-7-17/h2-4,6-11H,5,12-16H2,1H3,(H,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
UniChem
Similars
| PDB
PubMed
| n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia Corporation
Curated by ChEMBL
| Assay Description
Inhibition of leukotriene A4 hydrolase in human recombinant assay |
Bioorg Med Chem Lett 12: 3383-6 (2002)
BindingDB Entry DOI: 10.7270/Q2N8795W |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50121000
(CHEMBL116174 | {2-[2-(4-Benzyl-phenoxy)-ethyl]-2-a...)Show SMILES COC(=O)CC1CC2CC1CN2CCOc1ccc(Cc2ccccc2)cc1 |THB:4:5:11.10:8| Show InChI InChI=1S/C24H29NO3/c1-27-24(26)16-20-14-22-15-21(20)17-25(22)11-12-28-23-9-7-19(8-10-23)13-18-5-3-2-4-6-18/h2-10,20-22H,11-17H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia Corporation
Curated by ChEMBL
| Assay Description
Inhibition of leukotriene A4 hydrolase in human recombinant assay |
Bioorg Med Chem Lett 12: 3383-6 (2002)
BindingDB Entry DOI: 10.7270/Q2N8795W |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50121000
(CHEMBL116174 | {2-[2-(4-Benzyl-phenoxy)-ethyl]-2-a...)Show SMILES COC(=O)CC1CC2CC1CN2CCOc1ccc(Cc2ccccc2)cc1 |THB:4:5:11.10:8| Show InChI InChI=1S/C24H29NO3/c1-27-24(26)16-20-14-22-15-21(20)17-25(22)11-12-28-23-9-7-19(8-10-23)13-18-5-3-2-4-6-18/h2-10,20-22H,11-17H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia Corporation
Curated by ChEMBL
| Assay Description
Inhibition of leukotriene A4 hydrolase in human recombinant assay |
Bioorg Med Chem Lett 12: 3383-6 (2002)
BindingDB Entry DOI: 10.7270/Q2N8795W |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50121003
(1-[2-(4-Benzyl-phenoxy)-ethyl]-pyrrolidine-3-carbo...)Show InChI InChI=1S/C20H24N2O2/c21-20(23)18-10-11-22(15-18)12-13-24-19-8-6-17(7-9-19)14-16-4-2-1-3-5-16/h1-9,18H,10-15H2,(H2,21,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia Corporation
Curated by ChEMBL
| Assay Description
Inhibition of leukotriene A4 hydrolase in human recombinant assay |
Bioorg Med Chem Lett 12: 3383-6 (2002)
BindingDB Entry DOI: 10.7270/Q2N8795W |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50121009
(1-[2-(4-Benzyl-phenoxy)-ethyl]-pyrrolidin-3-ylamin...)Show InChI InChI=1S/C19H24N2O/c20-18-10-11-21(15-18)12-13-22-19-8-6-17(7-9-19)14-16-4-2-1-3-5-16/h1-9,18H,10-15,20H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia Corporation
Curated by ChEMBL
| Assay Description
Inhibition of leukotriene A4 hydrolase in human recombinant assay |
Bioorg Med Chem Lett 12: 3383-6 (2002)
BindingDB Entry DOI: 10.7270/Q2N8795W |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50085279
(1-[2-(4-Benzyl-phenoxy)-ethyl]-pyrrolidine | 1-[2-...)Show InChI InChI=1S/C19H23NO/c1-2-6-17(7-3-1)16-18-8-10-19(11-9-18)21-15-14-20-12-4-5-13-20/h1-3,6-11H,4-5,12-16H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| MMDB
PDB
PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia Corporation
Curated by ChEMBL
| Assay Description
Inhibition of leukotriene A4 hydrolase in human recombinant assay |
Bioorg Med Chem Lett 12: 3383-6 (2002)
BindingDB Entry DOI: 10.7270/Q2N8795W |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50121023
(1-[2-(4-Benzyl-phenoxy)-ethyl]-pyrrolidin-3-ol | C...)Show InChI InChI=1S/C19H23NO2/c21-18-10-11-20(15-18)12-13-22-19-8-6-17(7-9-19)14-16-4-2-1-3-5-16/h1-9,18,21H,10-15H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia Corporation
Curated by ChEMBL
| Assay Description
Inhibition of leukotriene A4 hydrolase in human recombinant assay |
Bioorg Med Chem Lett 12: 3383-6 (2002)
BindingDB Entry DOI: 10.7270/Q2N8795W |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50121010
(2-[2-(4-Benzyl-phenoxy)-ethyl]-2-aza-bicyclo[2.2.1...)Show SMILES COC(=O)C1CC2CC1CN2CCOc1ccc(Cc2ccccc2)cc1 |THB:2:4:10.9:7| Show InChI InChI=1S/C23H27NO3/c1-26-23(25)22-15-20-14-19(22)16-24(20)11-12-27-21-9-7-18(8-10-21)13-17-5-3-2-4-6-17/h2-10,19-20,22H,11-16H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia Corporation
Curated by ChEMBL
| Assay Description
Inhibition of leukotriene A4 hydrolase in human recombinant assay |
Bioorg Med Chem Lett 12: 3383-6 (2002)
BindingDB Entry DOI: 10.7270/Q2N8795W |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50121008
(CHEMBL114563 | N-{1-[2-(4-Benzyl-phenoxy)-ethyl]-p...)Show InChI InChI=1S/C22H28N2O2/c1-18(25)23-21-11-13-24(14-12-21)15-16-26-22-9-7-20(8-10-22)17-19-5-3-2-4-6-19/h2-10,21H,11-17H2,1H3,(H,23,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia Corporation
Curated by ChEMBL
| Assay Description
Inhibition of leukotriene A4 hydrolase in human recombinant assay |
Bioorg Med Chem Lett 12: 3383-6 (2002)
BindingDB Entry DOI: 10.7270/Q2N8795W |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50121001
(CHEMBL114494 | {1-[2-(4-Benzyl-phenoxy)-ethyl]-pip...)Show InChI InChI=1S/C21H27NO2/c23-17-20-10-12-22(13-11-20)14-15-24-21-8-6-19(7-9-21)16-18-4-2-1-3-5-18/h1-9,20,23H,10-17H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia Corporation
Curated by ChEMBL
| Assay Description
Inhibition of leukotriene A4 hydrolase in human recombinant assay |
Bioorg Med Chem Lett 12: 3383-6 (2002)
BindingDB Entry DOI: 10.7270/Q2N8795W |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50085285
(1-[2-(4-Benzyl-phenoxy)-ethyl]-piperidine | CHEMBL...)Show InChI InChI=1S/C20H25NO/c1-3-7-18(8-4-1)17-19-9-11-20(12-10-19)22-16-15-21-13-5-2-6-14-21/h1,3-4,7-12H,2,5-6,13-17H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia Corporation
Curated by ChEMBL
| Assay Description
Inhibition of leukotriene A4 hydrolase in human recombinant assay |
Bioorg Med Chem Lett 12: 3383-6 (2002)
BindingDB Entry DOI: 10.7270/Q2N8795W |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50121011
(1-[2-(4-Benzyl-phenoxy)-ethyl]-piperidine-4-carbox...)Show InChI InChI=1S/C22H28N2O2/c1-23-22(25)20-11-13-24(14-12-20)15-16-26-21-9-7-19(8-10-21)17-18-5-3-2-4-6-18/h2-10,20H,11-17H2,1H3,(H,23,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 57 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia Corporation
Curated by ChEMBL
| Assay Description
Inhibition of leukotriene A4 hydrolase in human recombinant assay |
Bioorg Med Chem Lett 12: 3383-6 (2002)
BindingDB Entry DOI: 10.7270/Q2N8795W |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50121018
(CHEMBL114264 | {1-[2-(4-Benzyl-phenoxy)-ethyl]-pyr...)Show InChI InChI=1S/C20H25N3O2/c21-20(24)22-18-10-11-23(15-18)12-13-25-19-8-6-17(7-9-19)14-16-4-2-1-3-5-16/h1-9,18H,10-15H2,(H3,21,22,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 81 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia Corporation
Curated by ChEMBL
| Assay Description
Inhibition of leukotriene A4 hydrolase in human recombinant assay |
Bioorg Med Chem Lett 12: 3383-6 (2002)
BindingDB Entry DOI: 10.7270/Q2N8795W |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50121005
(CHEMBL115227 | {1-[2-(4-Benzyl-phenoxy)-ethyl]-pip...)Show InChI InChI=1S/C21H27N3O2/c22-21(25)23-19-10-12-24(13-11-19)14-15-26-20-8-6-18(7-9-20)16-17-4-2-1-3-5-17/h1-9,19H,10-16H2,(H3,22,23,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 87 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia Corporation
Curated by ChEMBL
| Assay Description
Inhibition of leukotriene A4 hydrolase in human recombinant assay |
Bioorg Med Chem Lett 12: 3383-6 (2002)
BindingDB Entry DOI: 10.7270/Q2N8795W |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50121019
(({1-[2-(4-Benzyl-phenoxy)-ethyl]-piperidine-4-carb...)Show SMILES CCOC(=O)CNC(=O)C1CCN(CCOc2ccc(Cc3ccccc3)cc2)CC1 Show InChI InChI=1S/C25H32N2O4/c1-2-30-24(28)19-26-25(29)22-12-14-27(15-13-22)16-17-31-23-10-8-21(9-11-23)18-20-6-4-3-5-7-20/h3-11,22H,2,12-19H2,1H3,(H,26,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia Corporation
Curated by ChEMBL
| Assay Description
Inhibition of leukotriene A4 hydrolase in human recombinant assay |
Bioorg Med Chem Lett 12: 3383-6 (2002)
BindingDB Entry DOI: 10.7270/Q2N8795W |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50121007
(1-[2-(4-Benzyl-phenoxy)-ethyl]-piperidine-4-carbox...)Show InChI InChI=1S/C21H26N2O2/c22-21(24)19-10-12-23(13-11-19)14-15-25-20-8-6-18(7-9-20)16-17-4-2-1-3-5-17/h1-9,19H,10-16H2,(H2,22,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia Corporation
Curated by ChEMBL
| Assay Description
Inhibition of leukotriene A4 hydrolase in human recombinant assay |
Bioorg Med Chem Lett 12: 3383-6 (2002)
BindingDB Entry DOI: 10.7270/Q2N8795W |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50121014
(CHEMBL115188 | N-{1-[2-(4-Benzyl-phenoxy)-ethyl]-p...)Show InChI InChI=1S/C21H26N2O2/c1-17(24)22-20-11-12-23(16-20)13-14-25-21-9-7-19(8-10-21)15-18-5-3-2-4-6-18/h2-10,20H,11-16H2,1H3,(H,22,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia Corporation
Curated by ChEMBL
| Assay Description
Inhibition of leukotriene A4 hydrolase in human recombinant assay |
Bioorg Med Chem Lett 12: 3383-6 (2002)
BindingDB Entry DOI: 10.7270/Q2N8795W |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50121015
(2-{1-[2-(4-Benzyl-phenoxy)-ethyl]-pyrrolidin-3-yl}...)Show InChI InChI=1S/C21H26N2O2/c22-21(24)15-19-10-11-23(16-19)12-13-25-20-8-6-18(7-9-20)14-17-4-2-1-3-5-17/h1-9,19H,10-16H2,(H2,22,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia Corporation
Curated by ChEMBL
| Assay Description
Inhibition of leukotriene A4 hydrolase in human recombinant assay |
Bioorg Med Chem Lett 12: 3383-6 (2002)
BindingDB Entry DOI: 10.7270/Q2N8795W |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50121017
(1-[2-(4-Benzyl-phenoxy)-ethyl]-4-(1H-tetrazol-5-yl...)Show SMILES C(CN1CCC(CC1)c1nnn[nH]1)Oc1ccc(Cc2ccccc2)cc1 Show InChI InChI=1S/C21H25N5O/c1-2-4-17(5-3-1)16-18-6-8-20(9-7-18)27-15-14-26-12-10-19(11-13-26)21-22-24-25-23-21/h1-9,19H,10-16H2,(H,22,23,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| PubMed
| n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia Corporation
Curated by ChEMBL
| Assay Description
Inhibition of leukotriene A4 hydrolase in human recombinant assay |
Bioorg Med Chem Lett 12: 3383-6 (2002)
BindingDB Entry DOI: 10.7270/Q2N8795W |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50121002
(1-[2-(4-Benzyl-phenoxy)-ethyl]-piperidine-4-carbox...)Show InChI InChI=1S/C21H25NO3/c23-21(24)19-10-12-22(13-11-19)14-15-25-20-8-6-18(7-9-20)16-17-4-2-1-3-5-17/h1-9,19H,10-16H2,(H,23,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia Corporation
Curated by ChEMBL
| Assay Description
Inhibition of leukotriene A4 hydrolase in human recombinant assay |
Bioorg Med Chem Lett 12: 3383-6 (2002)
BindingDB Entry DOI: 10.7270/Q2N8795W |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50121016
(CHEMBL115170 | {1-[2-(4-Benzyl-phenoxy)-ethyl]-pyr...)Show InChI InChI=1S/C22H27NO3/c1-25-22(24)16-20-11-12-23(17-20)13-14-26-21-9-7-19(8-10-21)15-18-5-3-2-4-6-18/h2-10,20H,11-17H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 390 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia Corporation
Curated by ChEMBL
| Assay Description
Inhibition of leukotriene A4 hydrolase in human recombinant assay |
Bioorg Med Chem Lett 12: 3383-6 (2002)
BindingDB Entry DOI: 10.7270/Q2N8795W |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50121013
((S)-1-[2-(4-Benzyl-phenoxy)-ethyl]-pyrrolidine-2-c...)Show InChI InChI=1S/C21H25NO3/c1-24-21(23)20-8-5-13-22(20)14-15-25-19-11-9-18(10-12-19)16-17-6-3-2-4-7-17/h2-4,6-7,9-12,20H,5,8,13-16H2,1H3/t20-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| PubMed
| n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia Corporation
Curated by ChEMBL
| Assay Description
Inhibition of leukotriene A4 hydrolase in human recombinant assay |
Bioorg Med Chem Lett 12: 3383-6 (2002)
BindingDB Entry DOI: 10.7270/Q2N8795W |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50121004
(1-[2-(4-Benzyl-phenoxy)-ethyl]-piperidine-4-carbon...)Show InChI InChI=1S/C21H24N2O/c22-17-20-10-12-23(13-11-20)14-15-24-21-8-6-19(7-9-21)16-18-4-2-1-3-5-18/h1-9,20H,10-16H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 470 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia Corporation
Curated by ChEMBL
| Assay Description
Inhibition of leukotriene A4 hydrolase in human recombinant assay |
Bioorg Med Chem Lett 12: 3383-6 (2002)
BindingDB Entry DOI: 10.7270/Q2N8795W |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50121006
(4-[2-(4-Benzyl-phenoxy)-ethyl]-piperazine-1-carbox...)Show InChI InChI=1S/C20H25N3O2/c21-20(24)23-12-10-22(11-13-23)14-15-25-19-8-6-18(7-9-19)16-17-4-2-1-3-5-17/h1-9H,10-16H2,(H2,21,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia Corporation
Curated by ChEMBL
| Assay Description
Inhibition of leukotriene A4 hydrolase in human recombinant assay |
Bioorg Med Chem Lett 12: 3383-6 (2002)
BindingDB Entry DOI: 10.7270/Q2N8795W |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50121020
(1-[2-(4-Benzyl-phenoxy)-ethyl]-piperidine-4-carbox...)Show InChI InChI=1S/C23H29NO3/c1-2-26-23(25)21-12-14-24(15-13-21)16-17-27-22-10-8-20(9-11-22)18-19-6-4-3-5-7-19/h3-11,21H,2,12-18H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia Corporation
Curated by ChEMBL
| Assay Description
Inhibition of leukotriene A4 hydrolase in human recombinant assay |
Bioorg Med Chem Lett 12: 3383-6 (2002)
BindingDB Entry DOI: 10.7270/Q2N8795W |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50121021
(1-[2-(4-Benzyl-phenoxy)-ethyl]-piperidine-3-carbox...)Show InChI InChI=1S/C23H29NO3/c1-2-26-23(25)21-9-6-14-24(18-21)15-16-27-22-12-10-20(11-13-22)17-19-7-4-3-5-8-19/h3-5,7-8,10-13,21H,2,6,9,14-18H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia Corporation
Curated by ChEMBL
| Assay Description
Inhibition of leukotriene A4 hydrolase in human recombinant assay |
Bioorg Med Chem Lett 12: 3383-6 (2002)
BindingDB Entry DOI: 10.7270/Q2N8795W |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50121012
(1-[2-(4-Benzyl-phenoxy)-ethyl]-pyrrolidine-3-carbo...)Show InChI InChI=1S/C21H25NO3/c1-24-21(23)19-11-12-22(16-19)13-14-25-20-9-7-18(8-10-20)15-17-5-3-2-4-6-17/h2-10,19H,11-16H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia Corporation
Curated by ChEMBL
| Assay Description
Inhibition of leukotriene A4 hydrolase in human recombinant assay |
Bioorg Med Chem Lett 12: 3383-6 (2002)
BindingDB Entry DOI: 10.7270/Q2N8795W |
More data for this
Ligand-Target Pair | |
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