Found 8 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Serotonin N-acetyltransferase
(Homo sapiens (Human)) | BDBM85592
(AANAT Inhibitor, 12d)Show InChI InChI=1S/C12H12BrNO2S/c13-6-12(16)14-4-3-8-7-17-11-2-1-9(15)5-10(8)11/h1-2,5,7,15H,3-4,6H2,(H,14,16) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | 6.8 | 37 |
Université de Lille
| Assay Description
The compounds were evaluated in a human serotonin N-acetyltransferase assay. |
J Enzyme Inhib Med Chem 17: 409-14 (2002)
Article DOI: 10.1080/1475636021000005721
BindingDB Entry DOI: 10.7270/Q2610XWN |
More data for this
Ligand-Target Pair | |
Serotonin N-acetyltransferase
(Homo sapiens (Human)) | BDBM85590
(AANAT Inhibitor, 8h)Show InChI InChI=1S/C12H11BrFNOS/c13-6-12(16)15-4-3-8-7-17-11-2-1-9(14)5-10(8)11/h1-2,5,7H,3-4,6H2,(H,15,16) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 390 | n/a | n/a | n/a | n/a | 6.8 | 37 |
Université de Lille
| Assay Description
The compounds were evaluated in a human serotonin N-acetyltransferase assay. |
J Enzyme Inhib Med Chem 17: 409-14 (2002)
Article DOI: 10.1080/1475636021000005721
BindingDB Entry DOI: 10.7270/Q2610XWN |
More data for this
Ligand-Target Pair | |
Serotonin N-acetyltransferase
(Homo sapiens (Human)) | BDBM85587
(AANAT Inhibitor, 8d)Show InChI InChI=1S/C13H14BrNO2S/c1-17-10-2-3-12-11(6-10)9(8-18-12)4-5-15-13(16)7-14/h2-3,6,8H,4-5,7H2,1H3,(H,15,16) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 610 | n/a | n/a | n/a | n/a | 6.8 | 37 |
Université de Lille
| Assay Description
The compounds were evaluated in a human serotonin N-acetyltransferase assay. |
J Enzyme Inhib Med Chem 17: 409-14 (2002)
Article DOI: 10.1080/1475636021000005721
BindingDB Entry DOI: 10.7270/Q2610XWN |
More data for this
Ligand-Target Pair | |
Serotonin N-acetyltransferase
(Homo sapiens (Human)) | BDBM85588
(AANAT Inhibitor, 8e)Show InChI InChI=1S/C12H12BrNOS/c13-7-12(15)14-6-5-9-8-16-11-4-2-1-3-10(9)11/h1-4,8H,5-7H2,(H,14,15) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 680 | n/a | n/a | n/a | n/a | 6.8 | 37 |
Université de Lille
| Assay Description
The compounds were evaluated in a human serotonin N-acetyltransferase assay. |
J Enzyme Inhib Med Chem 17: 409-14 (2002)
Article DOI: 10.1080/1475636021000005721
BindingDB Entry DOI: 10.7270/Q2610XWN |
More data for this
Ligand-Target Pair | |
Serotonin N-acetyltransferase
(Homo sapiens (Human)) | BDBM85591
(AANAT Inhibitor, 8i)Show InChI InChI=1S/C14H16BrNOS/c1-2-10-3-4-13-12(7-10)11(9-18-13)5-6-16-14(17)8-15/h3-4,7,9H,2,5-6,8H2,1H3,(H,16,17) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 700 | n/a | n/a | n/a | n/a | 6.8 | 37 |
Université de Lille
| Assay Description
The compounds were evaluated in a human serotonin N-acetyltransferase assay. |
J Enzyme Inhib Med Chem 17: 409-14 (2002)
Article DOI: 10.1080/1475636021000005721
BindingDB Entry DOI: 10.7270/Q2610XWN |
More data for this
Ligand-Target Pair | |
Serotonin N-acetyltransferase
(Homo sapiens (Human)) | BDBM50282747
(2-Bromo-N-[2-(1H-indol-3-yl)-ethyl]-acetamide | AA...)Show InChI InChI=1S/C12H13BrN2O/c13-7-12(16)14-6-5-9-8-15-11-4-2-1-3-10(9)11/h1-4,8,15H,5-7H2,(H,14,16) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.43E+3 | n/a | n/a | n/a | n/a | 6.8 | 37 |
Université de Lille
| Assay Description
The compounds were evaluated in a human serotonin N-acetyltransferase assay. |
J Enzyme Inhib Med Chem 17: 409-14 (2002)
Article DOI: 10.1080/1475636021000005721
BindingDB Entry DOI: 10.7270/Q2610XWN |
More data for this
Ligand-Target Pair | |
Serotonin N-acetyltransferase
(Homo sapiens (Human)) | BDBM85589
(AANAT Inhibitor, 8g)Show InChI InChI=1S/C12H11Br2NOS/c13-6-12(16)15-4-3-8-7-17-11-2-1-9(14)5-10(8)11/h1-2,5,7H,3-4,6H2,(H,15,16) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.78E+3 | n/a | n/a | n/a | n/a | 6.8 | 37 |
Université de Lille
| Assay Description
The compounds were evaluated in a human serotonin N-acetyltransferase assay. |
J Enzyme Inhib Med Chem 17: 409-14 (2002)
Article DOI: 10.1080/1475636021000005721
BindingDB Entry DOI: 10.7270/Q2610XWN |
More data for this
Ligand-Target Pair | |
Serotonin N-acetyltransferase
(Homo sapiens (Human)) | BDBM85586
(AANAT Inhibitor, 8c)Show InChI InChI=1S/C13H14BrNO3/c1-17-10-2-3-12-11(6-10)9(8-18-12)4-5-15-13(16)7-14/h2-3,6,8H,4-5,7H2,1H3,(H,15,16) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | 6.8 | 37 |
Université de Lille
| Assay Description
The compounds were evaluated in a human serotonin N-acetyltransferase assay. |
J Enzyme Inhib Med Chem 17: 409-14 (2002)
Article DOI: 10.1080/1475636021000005721
BindingDB Entry DOI: 10.7270/Q2610XWN |
More data for this
Ligand-Target Pair | |
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