Affinity Data by PubMed id=13678406

PubMed code 13678406

Found 7 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50411207 (CHEMBL216927 \| CHEMBL553058) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Toledo Curated by ChEMBL					Assay Description Inhibitory activity was evaluated against Muscarinic acetylcholine receptor M2 expressed in A9 L cells				J Med Chem 46: 4273-86 (2003) Article DOI: 10.1021/jm0301235 BindingDB Entry DOI: 10.7270/Q2MG7QT4
The University of Toledo Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50107697 (1-[4-(1-methyl-1,2,3,6-tetrahydro-5-pyridinyl)-1,2...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.630	n/a	n/a	n/a	n/a	n/a	n/a
The University of Toledo Curated by ChEMBL					Assay Description Inhibitory activity was evaluated against Muscarinic acetylcholine receptor M2 expressed in A9 L cells				J Med Chem 46: 4273-86 (2003) Article DOI: 10.1021/jm0301235 BindingDB Entry DOI: 10.7270/Q2MG7QT4
The University of Toledo Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
The University of Toledo Curated by ChEMBL					Assay Description Inhibitory activity was evaluated against Muscarinic acetylcholine receptor M2 expressed in A9 L cells				J Med Chem 46: 4273-86 (2003) Article DOI: 10.1021/jm0301235 BindingDB Entry DOI: 10.7270/Q2MG7QT4
The University of Toledo Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50003359 (5-(4-Hexyloxy-[1,2,5]thiadiazol-3-yl)-1-methyl-1,2...) Show SMILES CCCCCCOc1nsnc1C1=CCCN(C)C1 \|t:13\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
The University of Toledo Curated by ChEMBL					Assay Description Inhibitory activity was evaluated against Muscarinic acetylcholine receptor M2 expressed in A9 L cells				J Med Chem 46: 4273-86 (2003) Article DOI: 10.1021/jm0301235 BindingDB Entry DOI: 10.7270/Q2MG7QT4
The University of Toledo Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50411207 (CHEMBL216927 \| CHEMBL553058) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
The University of Toledo Curated by ChEMBL					Assay Description Inhibitory activity was evaluated against Muscarinic acetylcholine receptor M4 expressed in A9 L cells ; Not determined				J Med Chem 46: 4273-86 (2003) Article DOI: 10.1021/jm0301235 BindingDB Entry DOI: 10.7270/Q2MG7QT4
The University of Toledo Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50003359 (5-(4-Hexyloxy-[1,2,5]thiadiazol-3-yl)-1-methyl-1,2...) Show SMILES CCCCCCOc1nsnc1C1=CCCN(C)C1 \|t:13\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
The University of Toledo Curated by ChEMBL					Assay Description Inhibitory activity was evaluated against Muscarinic acetylcholine receptor M4 expressed in A9 L cells				J Med Chem 46: 4273-86 (2003) Article DOI: 10.1021/jm0301235 BindingDB Entry DOI: 10.7270/Q2MG7QT4
The University of Toledo Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Toledo Curated by ChEMBL					Assay Description Inhibitory activity was evaluated against Muscarinic acetylcholine receptor M4 expressed in A9 L cells				J Med Chem 46: 4273-86 (2003) Article DOI: 10.1021/jm0301235 BindingDB Entry DOI: 10.7270/Q2MG7QT4
The University of Toledo Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%