Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50001450 ((SP)Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.120 | n/a | n/a | n/a | n/a | n/a | n/a |
Rochester Curated by ChEMBL | Assay Description Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to standard Tachykinin receptor 1 from rat forebrain membranes. | J Med Chem 35: 374-8 (1992) BindingDB Entry DOI: 10.7270/Q2VQ338K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50002373 (1-(1-ethynyl)-15a,17a-dimethyl-(1R,15aS,17aS)-2,3,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Rochester Curated by ChEMBL | Assay Description Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to standard Tachykinin receptor 1 from rat forebrain membranes. | J Med Chem 35: 374-8 (1992) BindingDB Entry DOI: 10.7270/Q2VQ338K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50002373 (1-(1-ethynyl)-15a,17a-dimethyl-(1R,15aS,17aS)-2,3,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
Rochester Curated by ChEMBL | Assay Description Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to standard Tachykinin receptor 1 from rat forebrain membranes. | J Med Chem 35: 374-8 (1992) BindingDB Entry DOI: 10.7270/Q2VQ338K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50002373 (1-(1-ethynyl)-15a,17a-dimethyl-(1R,15aS,17aS)-2,3,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Rochester Curated by ChEMBL | Assay Description Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to standard Tachykinin receptor 1 from rat forebrain membranes. | J Med Chem 35: 374-8 (1992) BindingDB Entry DOI: 10.7270/Q2VQ338K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50002384 (15a,17a-dimethyl-1-vinyl-(1R,15aS,17aS)-2,3,3a,3b,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 86 | n/a | n/a | n/a | n/a | n/a | n/a |
Rochester Curated by ChEMBL | Assay Description Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to standard Tachykinin receptor 1 from rat forebrain membranes. | J Med Chem 35: 374-8 (1992) BindingDB Entry DOI: 10.7270/Q2VQ338K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50002390 (15a,17a-dimethyl-1-(1-propynyl)-(1R,15aS,17aS)-2,3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Rochester Curated by ChEMBL | Assay Description Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to Tachykinin receptor 1 from rat forebrain membranes. | J Med Chem 35: 374-8 (1992) BindingDB Entry DOI: 10.7270/Q2VQ338K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50002389 (1,15a,17a-trimethyl-(1S,15aS,17aS)-2,3,3a,3b,4,5,5...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Rochester Curated by ChEMBL | Assay Description Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to standard Tachykinin receptor 1 from rat forebrain membranes. | J Med Chem 35: 374-8 (1992) BindingDB Entry DOI: 10.7270/Q2VQ338K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50002375 (15a,17a-dimethyl-(1S,15aS,17aS)-2,3,3a,3b,4,5,5a,6...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Rochester Curated by ChEMBL | Assay Description Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to standard Tachykinin receptor 1 from rat forebrain membranes. | J Med Chem 35: 374-8 (1992) BindingDB Entry DOI: 10.7270/Q2VQ338K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50002377 (15a,17a-dimethyl-1-(2-propynyl)-(1R,15aS,17aS)-2,3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
Rochester Curated by ChEMBL | Assay Description Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to Tachykinin receptor 1 from rat forebrain membranes. | J Med Chem 35: 374-8 (1992) BindingDB Entry DOI: 10.7270/Q2VQ338K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50002378 (1-(1-ethynyl)-17a,19a-dimethyl-(1R,5aS,17aS,19aS)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
Rochester Curated by ChEMBL | Assay Description Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to standard Tachykinin receptor 1 from rat forebrain membranes. | J Med Chem 35: 374-8 (1992) BindingDB Entry DOI: 10.7270/Q2VQ338K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50002382 (1-(1-ethynyl)-1-hydroxy-16a,18a-dimethyl-(1R,5aS,1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Rochester Curated by ChEMBL | Assay Description Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to standard Tachykinin receptor 1 from rat forebrain membranes. | J Med Chem 35: 374-8 (1992) BindingDB Entry DOI: 10.7270/Q2VQ338K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50002394 (1-(1-ethynyl)-13a,15a-dimethyl-(1R,5aS,13aS,15aS)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Rochester Curated by ChEMBL | Assay Description Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to standard Tachykinin receptor 1 from rat forebrain membranes. | J Med Chem 35: 374-8 (1992) BindingDB Entry DOI: 10.7270/Q2VQ338K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50002396 (CHEMBL125109 | methyl 4-[4,17-dihydroxy-15a,17a-di...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Rochester Curated by ChEMBL | Assay Description Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to standard Tachykinin receptor 1 from rat forebrain membranes. | J Med Chem 35: 374-8 (1992) BindingDB Entry DOI: 10.7270/Q2VQ338K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50002391 (1-ethyl-15a,17a-dimethyl-(1S,15aS,17aS)-2,3,3a,3b,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Rochester Curated by ChEMBL | Assay Description Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to standard Tachykinin receptor 1 from rat forebrain membranes. | J Med Chem 35: 374-8 (1992) BindingDB Entry DOI: 10.7270/Q2VQ338K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50002393 (11a-methyl-11-vinyl-(11aS)-7,7a,8,9,11a,12-hexahyd...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Rochester Curated by ChEMBL | Assay Description Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to standard Tachykinin receptor 1 from rat forebrain membranes. | J Med Chem 35: 374-8 (1992) BindingDB Entry DOI: 10.7270/Q2VQ338K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50002380 (15a,17a-dimethyl-(1S,15aS,17aS)-2,3,3a,3b,4,5,5a,6...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Rochester Curated by ChEMBL | Assay Description Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to Tachykinin receptor 1 from rat forebrain membranes. | J Med Chem 35: 374-8 (1992) BindingDB Entry DOI: 10.7270/Q2VQ338K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50002392 (1-(1,5-dimethylhexyl)-15a,17a-dimethyl-(15aS,17aR)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Rochester Curated by ChEMBL | Assay Description Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to Tachykinin receptor 1 from rat forebrain membranes. | J Med Chem 35: 374-8 (1992) BindingDB Entry DOI: 10.7270/Q2VQ338K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50002395 (1-(1-ethynyl)-14a,16a-dimethyl-(1R,5aS,14aS,16aS)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Rochester Curated by ChEMBL | Assay Description Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to standard Tachykinin receptor 1 from rat forebrain membranes. | J Med Chem 35: 374-8 (1992) BindingDB Entry DOI: 10.7270/Q2VQ338K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50002376 (4-[4,17-dihydroxy-15a,17a-dimethyl-(4R,15aS,17S,17...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Rochester Curated by ChEMBL | Assay Description Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to standard Tachykinin receptor 1 from rat forebrain membranes. | J Med Chem 35: 374-8 (1992) BindingDB Entry DOI: 10.7270/Q2VQ338K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50002372 (1,2,3,4-tetrahydrobenzo[4,5]imidazo[2,1-b]quinazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Rochester Curated by ChEMBL | Assay Description Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to Tachykinin receptor 1 from rat forebrain membranes. | J Med Chem 35: 374-8 (1992) BindingDB Entry DOI: 10.7270/Q2VQ338K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50002386 (CHEMBL125493 | methyl 15a,17a-dimethyl-(1S,15aS,17...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Rochester Curated by ChEMBL | Assay Description Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to Tachykinin receptor 1 from rat forebrain membranes. | J Med Chem 35: 374-8 (1992) BindingDB Entry DOI: 10.7270/Q2VQ338K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50002397 (2,4-dimethylbenzo[4,5]imidazo[1,2-a]pyrimidine | C...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Rochester Curated by ChEMBL | Assay Description Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to standard Tachykinin receptor 1 from rat forebrain membranes. | J Med Chem 35: 374-8 (1992) BindingDB Entry DOI: 10.7270/Q2VQ338K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50002381 (1-(1-ethynyl)-1-methoxy-15a,17a-dimethyl-(1R,15aS,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Rochester Curated by ChEMBL | Assay Description Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to standard Tachykinin receptor 1 from rat forebrain membranes. | J Med Chem 35: 374-8 (1992) BindingDB Entry DOI: 10.7270/Q2VQ338K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50002383 (15a,17a-dimethyl-1-phenyl-(1S,15aS,17aS)-2,3,3a,3b...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Rochester Curated by ChEMBL | Assay Description Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to Tachykinin receptor 1 from rat forebrain membranes. | J Med Chem 35: 374-8 (1992) BindingDB Entry DOI: 10.7270/Q2VQ338K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50002388 (15a,17a-dimethyl-(15aS,17aS)-2,3,3a,3b,4,5,5a,6,15...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Rochester Curated by ChEMBL | Assay Description Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to Tachykinin receptor 1 from rat forebrain membranes. | J Med Chem 35: 374-8 (1992) BindingDB Entry DOI: 10.7270/Q2VQ338K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50002379 (15a,17a-dimethyl-(15aS,17aS)-2,3,3a,3b,4,5,5a,6,15...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Rochester Curated by ChEMBL | Assay Description Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to standard Tachykinin receptor 1 from rat forebrain membranes. | J Med Chem 35: 374-8 (1992) BindingDB Entry DOI: 10.7270/Q2VQ338K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Rattus norvegicus (rat)) | BDBM50002385 (1-(1-ethynyl)-15a,17a-dimethyl-(1R,5aS,15aS,17aS)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Rochester Curated by ChEMBL | Assay Description Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to standard Tachykinin receptor 1 from rat forebrain membranes. | J Med Chem 35: 374-8 (1992) BindingDB Entry DOI: 10.7270/Q2VQ338K | |||||||||||
More data for this Ligand-Target Pair |