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PubMed code 15006387

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ceramide glucosyltransferase


(Homo sapiens (Human))
BDBM50141446
PNG
(CHEMBL34778 | Hexadecanoic acid [2-(2,3-dihydro-be...)
Show SMILES CCCCCCCCCCCCCCCC(=O)NC(CN1CCCC1)C(O)c1ccc2OCCOc2c1
Show InChI InChI=1S/C31H52N2O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17-30(34)32-27(25-33-20-15-16-21-33)31(35)26-18-19-28-29(24-26)37-23-22-36-28/h18-19,24,27,31,35H,2-17,20-23,25H2,1H3,(H,32,34)
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 90n/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Inhibitory concentration against glucosylceramide synthase in MDCK cell line


Bioorg Med Chem Lett 14: 1487-90 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.013
BindingDB Entry DOI: 10.7270/Q2C828Q8
More data for this
Ligand-Target Pair
Ceramide glucosyltransferase


(Homo sapiens (Human))
BDBM50141445
PNG
(CHEMBL34780 | Hexadecanoic acid [2-hydroxy-2-(4-hy...)
Show SMILES CCCCCCCCCCCCCCCC(=O)NC(CN1CCCC1)C(O)c1ccc(O)cc1
Show InChI InChI=1S/C29H50N2O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17-28(33)30-27(24-31-22-15-16-23-31)29(34)25-18-20-26(32)21-19-25/h18-21,27,29,32,34H,2-17,22-24H2,1H3,(H,30,33)
NCI pathway
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GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 90n/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Inhibitory concentration against glucosylceramide synthase in MDCK cell line


Bioorg Med Chem Lett 14: 1487-90 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.013
BindingDB Entry DOI: 10.7270/Q2C828Q8
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%