Affinity Data by PubMed id=15081038

PubMed code 15081038

Found 7 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50144809 (5,7-Dichloro-3-hydroxy-1H-quinazoline-2,4-dione \| ...) Show SMILES On1c(=O)[nH]c2cc(Cl)cc(Cl)c2c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Firenze Curated by ChEMBL					Assay Description Ability of compound to displace [3H]-glycine from N-methyl-D-aspartate glutamate receptor 1 from in cerebral cortex synaptic membranes				Bioorg Med Chem Lett 14: 2345-9 (2004) Article DOI: 10.1016/j.bmcl.2004.01.109 BindingDB Entry DOI: 10.7270/Q29W0DZW
Universita' degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50144806 (7-Chloro-3-hydroxy-1H-quinazoline-2,4-dione \| 7-ch...) Show SMILES On1c(=O)[nH]c2cc(Cl)ccc2c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Firenze Curated by ChEMBL					Assay Description Ability of compound to displace [3H]-glycine from N-methyl-D-aspartate glutamate receptor 1 from in cerebral cortex synaptic membranes				Bioorg Med Chem Lett 14: 2345-9 (2004) Article DOI: 10.1016/j.bmcl.2004.01.109 BindingDB Entry DOI: 10.7270/Q29W0DZW
Universita' degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50144808 (6,7-Dichloro-3-hydroxy-1H-quinazoline-2,4-dione \| ...) Show SMILES On1c(=O)[nH]c2cc(Cl)c(Cl)cc2c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Firenze Curated by ChEMBL					Assay Description Ability of compound to displace [3H]-glycine from N-methyl-D-aspartate glutamate receptor 1 from in cerebral cortex synaptic membranes				Bioorg Med Chem Lett 14: 2345-9 (2004) Article DOI: 10.1016/j.bmcl.2004.01.109 BindingDB Entry DOI: 10.7270/Q29W0DZW
Universita' degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50144810 (7-Chloro-3-hydroxy-6-nitro-1H-quinazoline-2,4-dion...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Firenze Curated by ChEMBL					Assay Description Ability of compound to displace [3H]-glycine from N-methyl-D-aspartate glutamate receptor 1 from in cerebral cortex synaptic membranes				Bioorg Med Chem Lett 14: 2345-9 (2004) Article DOI: 10.1016/j.bmcl.2004.01.109 BindingDB Entry DOI: 10.7270/Q29W0DZW
Universita' degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50144811 (6-Amino-7-chloro-3-hydroxy-1H-quinazoline-2,4-dion...) Show SMILES Nc1cc2c(cc1Cl)[nH]c(=O)n(O)c2=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.06E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Firenze Curated by ChEMBL					Assay Description Ability of compound to displace [3H]-glycine from N-methyl-D-aspartate glutamate receptor 1 from in cerebral cortex synaptic membranes				Bioorg Med Chem Lett 14: 2345-9 (2004) Article DOI: 10.1016/j.bmcl.2004.01.109 BindingDB Entry DOI: 10.7270/Q29W0DZW
Universita' degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50144812 (5,7-Dichloro-3-phenyl-1H-quinazoline-2,4-dione \| C...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Firenze Curated by ChEMBL					Assay Description Ability of compound to displace [3H]-glycine from N-methyl-D-aspartate glutamate receptor 1 from in cerebral cortex synaptic membranes				Bioorg Med Chem Lett 14: 2345-9 (2004) Article DOI: 10.1016/j.bmcl.2004.01.109 BindingDB Entry DOI: 10.7270/Q29W0DZW
Universita' degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50144807 (7-Chloro-3-hydroxy-6-[1,2,4]triazol-4-yl-1H-quinaz...) Show SMILES On1c(=O)[nH]c2cc(Cl)c(cc2c1=O)-n1cnnc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Firenze Curated by ChEMBL					Assay Description Ability of compound to displace [3H]-glycine from N-methyl-D-aspartate glutamate receptor 1 from in cerebral cortex synaptic membranes				Bioorg Med Chem Lett 14: 2345-9 (2004) Article DOI: 10.1016/j.bmcl.2004.01.109 BindingDB Entry DOI: 10.7270/Q29W0DZW
Universita' degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%