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PubMed code 15387673

Compile data set for download or QSAR
Found 3 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DNA polymerase beta


(Rattus norvegicus)
BDBM50237597
PNG
(7-hydroxy-3,7'-dicoumaryl ether | 7-hydroxy-3-(2-o...)
Show SMILES Oc1ccc2cc(Oc3ccc4ccc(=O)oc4c3)c(=O)oc2c1
Show InChI InChI=1S/C18H10O6/c19-12-4-1-11-7-16(18(21)24-14(11)8-12)22-13-5-2-10-3-6-17(20)23-15(10)9-13/h1-9,19H
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Article
PubMed
n/an/a 2.25E+4n/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Inhibition of lyase activity of rat DNA polymerase beta after 30 mins


J Nat Prod 67: 1608-10 (2004)


Article DOI: 10.1021/np040127s
BindingDB Entry DOI: 10.7270/Q2JH3KZG
More data for this
Ligand-Target Pair
DNA polymerase beta


(Rattus norvegicus)
BDBM50269808
PNG
(6,7-dihydroxy-3,7'-dicoumaryl ether | CHEMBL462972)
Show SMILES Oc1cc2cc(Oc3ccc4ccc(=O)oc4c3)c(=O)oc2cc1O
Show InChI InChI=1S/C18H10O7/c19-12-5-10-6-16(18(22)25-15(10)8-13(12)20)23-11-3-1-9-2-4-17(21)24-14(9)7-11/h1-8,19-20H
PDB
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Article
PubMed
n/an/a 9.48E+4n/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Inhibition of lyase activity of rat DNA polymerase beta after 30 mins


J Nat Prod 67: 1608-10 (2004)


Article DOI: 10.1021/np040127s
BindingDB Entry DOI: 10.7270/Q2JH3KZG
More data for this
Ligand-Target Pair
DNA polymerase beta


(Rattus norvegicus)
BDBM50241949
PNG
(7-hydroxy-6-methoxy-3,7'-dicoumaryl ether | CHEMBL...)
Show SMILES COc1cc2cc(Oc3ccc4ccc(=O)oc4c3)c(=O)oc2cc1O
Show InChI InChI=1S/C19H12O7/c1-23-16-6-11-7-17(19(22)26-15(11)9-13(16)20)24-12-4-2-10-3-5-18(21)25-14(10)8-12/h2-9,20H,1H3
PDB
MMDB

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Article
PubMed
n/an/a 1.22E+5n/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Inhibition of lyase activity of rat DNA polymerase beta after 30 mins


J Nat Prod 67: 1608-10 (2004)


Article DOI: 10.1021/np040127s
BindingDB Entry DOI: 10.7270/Q2JH3KZG
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%