Affinity Data by PubMed id=15771445

PubMed code 15771445

Found 22 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Androgen receptor (Homo sapiens (Human))	BDBM50367916 (METHYLTRIENOLONE \| Metribolone \| R-1881) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	n/a	0.560	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Dissociation constant for [3H]R-1881 binding to human androgen receptor at 283 K				J Med Chem 48: 2026-35 (2005) Article DOI: 10.1021/jm040842z BindingDB Entry DOI: 10.7270/Q2J67HQX
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Progesterone receptor (Homo sapiens (Human))	BDBM50422735 (CHEMBL2311103 \| ORG-2058) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Dissociation constant for [3H]-ORG2058 at human progesterone receptor at 278 K				J Med Chem 48: 2026-35 (2005) Article DOI: 10.1021/jm040842z BindingDB Entry DOI: 10.7270/Q2J67HQX
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50422735 (CHEMBL2311103 \| ORG-2058) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Dissociation constant for [3H]ORG2058 at human progesterone receptor at 293K				J Med Chem 48: 2026-35 (2005) Article DOI: 10.1021/jm040842z BindingDB Entry DOI: 10.7270/Q2J67HQX
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50422735 (CHEMBL2311103 \| ORG-2058) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Dissociation constant for [3H]ORG2058 at human progesterone receptor at 308 K				J Med Chem 48: 2026-35 (2005) Article DOI: 10.1021/jm040842z BindingDB Entry DOI: 10.7270/Q2J67HQX
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50367916 (METHYLTRIENOLONE \| Metribolone \| R-1881) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	n/a	0.740	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Dissociation constant value of the radiolabeled compound against the androgen receptor 293 K				J Med Chem 48: 2026-35 (2005) Article DOI: 10.1021/jm040842z BindingDB Entry DOI: 10.7270/Q2J67HQX
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Adenosine receptor A1 (Homo sapiens (Human))	BDBM15336 (1-methyl-3-(2-methylpropyl)-2,3,6,7-tetrahydro-1H-...) Show SMILES CC(C)Cn1c2nc[nH]c2c(=O)n(C)c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Dissociation constant against Adenosine A1 receptor				J Med Chem 48: 2026-35 (2005) Article DOI: 10.1021/jm040842z BindingDB Entry DOI: 10.7270/Q2J67HQX
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50367916 (METHYLTRIENOLONE \| Metribolone \| R-1881) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	n/a	0.610	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Dissociation constant for [3H]R-1881 binding to human androgen receptor at 273 K				J Med Chem 48: 2026-35 (2005) Article DOI: 10.1021/jm040842z BindingDB Entry DOI: 10.7270/Q2J67HQX
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Progesterone receptor (Homo sapiens (Human))	BDBM50422735 (CHEMBL2311103 \| ORG-2058) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Dissociation constant for [3H]ORG2058 at human progesterone receptor at 303 K				J Med Chem 48: 2026-35 (2005) Article DOI: 10.1021/jm040842z BindingDB Entry DOI: 10.7270/Q2J67HQX
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM10847 (1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dion...) Show SMILES Cn1c2nc[nH]c2c(=O)n(C)c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Dissociation constant against Adenosine A1 receptor				J Med Chem 48: 2026-35 (2005) Article DOI: 10.1021/jm040842z BindingDB Entry DOI: 10.7270/Q2J67HQX
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50422735 (CHEMBL2311103 \| ORG-2058) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Dissociation constant for [3H]ORG2058 at human progesterone receptor at 273 K				J Med Chem 48: 2026-35 (2005) Article DOI: 10.1021/jm040842z BindingDB Entry DOI: 10.7270/Q2J67HQX
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50367916 (METHYLTRIENOLONE \| Metribolone \| R-1881) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	n/a	0.680	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Dissociation constant for [3H]R-1881 binding to human androgen receptor at 288 K				J Med Chem 48: 2026-35 (2005) Article DOI: 10.1021/jm040842z BindingDB Entry DOI: 10.7270/Q2J67HQX
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Adenosine receptor A1 (Homo sapiens (Human))	BDBM21220 ((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	8.60	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Dissociation constant against Adenosine A1 receptor				J Med Chem 48: 2026-35 (2005) Article DOI: 10.1021/jm040842z BindingDB Entry DOI: 10.7270/Q2J67HQX
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50422735 (CHEMBL2311103 \| ORG-2058) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Dissociation constant for [3H]-ORG2058 at human progesterone receptor at 283 K				J Med Chem 48: 2026-35 (2005) Article DOI: 10.1021/jm040842z BindingDB Entry DOI: 10.7270/Q2J67HQX
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50422735 (CHEMBL2311103 \| ORG-2058) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Dissociation constant for [3H]ORG2058 at human progesterone receptor at 298 K				J Med Chem 48: 2026-35 (2005) Article DOI: 10.1021/jm040842z BindingDB Entry DOI: 10.7270/Q2J67HQX
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM10849 (1,3,7-trimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-d...) Show SMILES Cn1cnc2n(C)c(=O)n(C)c(=O)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	n/a	4.50E+4	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Dissociation constant against Adenosine A1 receptor				J Med Chem 48: 2026-35 (2005) Article DOI: 10.1021/jm040842z BindingDB Entry DOI: 10.7270/Q2J67HQX
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50422735 (CHEMBL2311103 \| ORG-2058) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Dissociation constant for [3H]-ORG2058 at human progesterone receptor at 310K				J Med Chem 48: 2026-35 (2005) Article DOI: 10.1021/jm040842z BindingDB Entry DOI: 10.7270/Q2J67HQX
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50422735 (CHEMBL2311103 \| ORG-2058) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Dissociation constant for [3H]ORG2058 at human progesterone receptor at 288 K				J Med Chem 48: 2026-35 (2005) Article DOI: 10.1021/jm040842z BindingDB Entry DOI: 10.7270/Q2J67HQX
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50367916 (METHYLTRIENOLONE \| Metribolone \| R-1881) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	n/a	1.21	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Dissociation constant for [3H]R-1881 binding to human androgen receptor at 303 K				J Med Chem 48: 2026-35 (2005) Article DOI: 10.1021/jm040842z BindingDB Entry DOI: 10.7270/Q2J67HQX
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Androgen receptor (Homo sapiens (Human))	BDBM50367916 (METHYLTRIENOLONE \| Metribolone \| R-1881) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	n/a	0.520	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Dissociation constant for [3H]R-1881 binding to human androgen receptor at 278 K				J Med Chem 48: 2026-35 (2005) Article DOI: 10.1021/jm040842z BindingDB Entry DOI: 10.7270/Q2J67HQX
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Androgen receptor (Homo sapiens (Human))	BDBM50367916 (METHYLTRIENOLONE \| Metribolone \| R-1881) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	n/a	1.51	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Dissociation constant for [3H]R-1881 binding to human androgen receptor at 308 K				J Med Chem 48: 2026-35 (2005) Article DOI: 10.1021/jm040842z BindingDB Entry DOI: 10.7270/Q2J67HQX
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Androgen receptor (Homo sapiens (Human))	BDBM50367916 (METHYLTRIENOLONE \| Metribolone \| R-1881) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	n/a	1.95	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Dissociation constant for [3H]R-1881 binding to human androgen receptor at 310K				J Med Chem 48: 2026-35 (2005) Article DOI: 10.1021/jm040842z BindingDB Entry DOI: 10.7270/Q2J67HQX
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Androgen receptor (Homo sapiens (Human))	BDBM50367916 (METHYLTRIENOLONE \| Metribolone \| R-1881) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	n/a	0.990	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Dissociation constant for [3H]R-1881 binding to human androgen receptor at 298 K				J Med Chem 48: 2026-35 (2005) Article DOI: 10.1021/jm040842z BindingDB Entry DOI: 10.7270/Q2J67HQX
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)

* indicates data uncertainty>20%