Affinity Data by PubMed id=15780608

PubMed code 15780608

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Pharmaceutical Education and Research (NIPER) Curated by ChEMBL					Assay Description Inhibitory concentration against Prostaglandin G/H synthase 2 from sheep placenta at 100 uM				Bioorg Med Chem Lett 15: 1793-7 (2005) Article DOI: 10.1016/j.bmcl.2005.02.039 BindingDB Entry DOI: 10.7270/Q20V8DJD
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50163748 ((E)-3,5-Bis[beta-(4-Hydroxy-3-methoxyphenyl)-ethen...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Pharmaceutical Education and Research (NIPER) Curated by ChEMBL					Assay Description Anti-oxidant activity in DPPH radicak scavenging assay; n=3-4				Bioorg Med Chem Lett 15: 1793-7 (2005) Article DOI: 10.1016/j.bmcl.2005.02.039 BindingDB Entry DOI: 10.7270/Q20V8DJD
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50163745 (4,40-(1E,10E)-2,20-(Isoxazole-3,5-diyl)bis(ethene-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Pharmaceutical Education and Research (NIPER) Curated by ChEMBL					Assay Description Anti-oxidant activity in DPPH radicak scavenging assay; n=3-4				Bioorg Med Chem Lett 15: 1793-7 (2005) Article DOI: 10.1016/j.bmcl.2005.02.039 BindingDB Entry DOI: 10.7270/Q20V8DJD
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50067040 (((E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-hept...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.11E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Pharmaceutical Education and Research (NIPER) Curated by ChEMBL					Assay Description Anti-oxidant activity in DPPH radicak scavenging assay; n=3-4				Bioorg Med Chem Lett 15: 1793-7 (2005) Article DOI: 10.1016/j.bmcl.2005.02.039 BindingDB Entry DOI: 10.7270/Q20V8DJD
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50359629 (TROLOX) Show SMILES Cc1c(C)c2OC(C)(CCc2c(C)c1O)C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Pharmaceutical Education and Research (NIPER) Curated by ChEMBL					Assay Description Anti-oxidant activity in DPPH radical scavenging assay; n=3-4				Bioorg Med Chem Lett 15: 1793-7 (2005) Article DOI: 10.1016/j.bmcl.2005.02.039 BindingDB Entry DOI: 10.7270/Q20V8DJD
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50009859 ((+-)-2-(p-isobutylphenyl)propionic acid \| (+-)-alp...) Show SMILES CC(C)Cc1ccc(cc1)C(C)C(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1.44E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Pharmaceutical Education and Research (NIPER) Curated by ChEMBL					Assay Description Inhibitory concentration against Prostaglandin G/H synthase 1 of ram seminal vesicles at 100 uM				Bioorg Med Chem Lett 15: 1793-7 (2005) Article DOI: 10.1016/j.bmcl.2005.02.039 BindingDB Entry DOI: 10.7270/Q20V8DJD
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50163747 (4-((E)-2-{5-[(E)-2-(4-Hydroxy-phenyl)-vinyl]-1H-py...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.55E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Pharmaceutical Education and Research (NIPER) Curated by ChEMBL					Assay Description Anti-oxidant activity in DPPH radicak scavenging assay; n=3-4				Bioorg Med Chem Lett 15: 1793-7 (2005) Article DOI: 10.1016/j.bmcl.2005.02.039 BindingDB Entry DOI: 10.7270/Q20V8DJD
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50163743 (4-((E)-2-{5-[(E)-2-(4-Hydroxy-phenyl)-vinyl]-isoxa...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Pharmaceutical Education and Research (NIPER) Curated by ChEMBL					Assay Description Anti-oxidant activity in DPPH radicak scavenging assay; n=3-4				Bioorg Med Chem Lett 15: 1793-7 (2005) Article DOI: 10.1016/j.bmcl.2005.02.039 BindingDB Entry DOI: 10.7270/Q20V8DJD
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50163744 ((1E,4Z,6E)-5-Hydroxy-1-(4-hydroxy-3-methoxy-phenyl...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Pharmaceutical Education and Research (NIPER) Curated by ChEMBL					Assay Description Anti-oxidant activity in DPPH radicak scavenging assay; n=3-4				Bioorg Med Chem Lett 15: 1793-7 (2005) Article DOI: 10.1016/j.bmcl.2005.02.039 BindingDB Entry DOI: 10.7270/Q20V8DJD
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50163746 (4-((E)-2-{3-[(E)-2-(4-hydroxyphenyl)vinyl]-1H-pyra...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Pharmaceutical Education and Research (NIPER) Curated by ChEMBL					Assay Description Anti-oxidant activity in DPPH radicak scavenging assay; n=3-4				Bioorg Med Chem Lett 15: 1793-7 (2005) Article DOI: 10.1016/j.bmcl.2005.02.039 BindingDB Entry DOI: 10.7270/Q20V8DJD
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50059989 ((1E,4Z,6E)-5-Hydroxy-1,7-bis-(4-hydroxy-phenyl)-he...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.64E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Pharmaceutical Education and Research (NIPER) Curated by ChEMBL					Assay Description Anti-oxidant activity in DPPH radicak scavenging assay; n=3-4				Bioorg Med Chem Lett 15: 1793-7 (2005) Article DOI: 10.1016/j.bmcl.2005.02.039 BindingDB Entry DOI: 10.7270/Q20V8DJD
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50009859 ((+-)-2-(p-isobutylphenyl)propionic acid \| (+-)-alp...) Show SMILES CC(C)Cc1ccc(cc1)C(C)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.66E+5	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Pharmaceutical Education and Research (NIPER) Curated by ChEMBL					Assay Description Inhibitory concentration against Prostaglandin G/H synthase 2 from sheep placenta at 100 uM				Bioorg Med Chem Lett 15: 1793-7 (2005) Article DOI: 10.1016/j.bmcl.2005.02.039 BindingDB Entry DOI: 10.7270/Q20V8DJD
					More data for this Ligand-Target Pair				3D Structure (crystal)

* indicates data uncertainty>20%