Found 52 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410112
(CHEMBL181108)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(Oc3cccc(NC(C)=O)c3)ccc12)C(=O)OC(C)(C)C)C(C)C Show InChI InChI=1S/C31H44N4O5/c1-20(2)34(21(3)4)17-15-32-29(37)28-27-13-12-26(39-25-11-9-10-24(19-25)33-22(5)36)18-23(27)14-16-35(28)30(38)40-31(6,7)8/h9-13,18-21,28H,14-17H2,1-8H3,(H,32,37)(H,33,36) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 12 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410114
(CHEMBL360547)Show SMILES COc1ccc(Oc2ccc3C(N(CCc3c2)C(=O)OC(C)(C)C)C(=O)NCCN(C(C)C)C(C)C)cc1 Show InChI InChI=1S/C30H43N3O5/c1-20(2)32(21(3)4)18-16-31-28(34)27-26-14-13-25(37-24-11-9-23(36-8)10-12-24)19-22(26)15-17-33(27)29(35)38-30(5,6)7/h9-14,19-21,27H,15-18H2,1-8H3,(H,31,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.490 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410128
(CHEMBL129637)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(OCc3ccccc3)ccc12)C(=O)C(C(C)=O)c1ccccc1)C(C)C Show InChI InChI=1S/C35H43N3O4/c1-24(2)37(25(3)4)21-19-36-34(40)33-31-17-16-30(42-23-27-12-8-6-9-13-27)22-29(31)18-20-38(33)35(41)32(26(5)39)28-14-10-7-11-15-28/h6-17,22,24-25,32-33H,18-21,23H2,1-5H3,(H,36,40) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 9.20 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410104
(CHEMBL181764)Show SMILES COC(=O)C(C)(C)OC(=O)N1CCc2cc(OCc3ccccc3)ccc2C1C(=O)NCCN(C(C)C)C(C)C Show InChI InChI=1S/C31H43N3O6/c1-21(2)33(22(3)4)18-16-32-28(35)27-26-14-13-25(39-20-23-11-9-8-10-12-23)19-24(26)15-17-34(27)30(37)40-31(5,6)29(36)38-7/h8-14,19,21-22,27H,15-18,20H2,1-7H3,(H,32,35) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410132
(CHEMBL434152)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(OCc3ccccc3)ccc12)C(=O)C(NC(C)=O)c1ccccc1)C(C)C Show InChI InChI=1S/C35H44N4O4/c1-24(2)38(25(3)4)21-19-36-34(41)33-31-17-16-30(43-23-27-12-8-6-9-13-27)22-29(31)18-20-39(33)35(42)32(37-26(5)40)28-14-10-7-11-15-28/h6-17,22,24-25,32-33H,18-21,23H2,1-5H3,(H,36,41)(H,37,40) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 19.7 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410140
(CHEMBL181123)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(OCc3ccccc3)ccc12)C(=O)S(=O)(=O)Cc1ccccc1)C(C)C Show InChI InChI=1S/C33H41N3O5S/c1-24(2)35(25(3)4)20-18-34-32(37)31-30-16-15-29(41-22-26-11-7-5-8-12-26)21-28(30)17-19-36(31)33(38)42(39,40)23-27-13-9-6-10-14-27/h5-16,21,24-25,31H,17-20,22-23H2,1-4H3,(H,34,37) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 7.30 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410116
(CHEMBL180337)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(OCc3ccccc3)ccc12)C(=O)OCc1ccccc1)C(C)C Show InChI InChI=1S/C33H41N3O4/c1-24(2)35(25(3)4)20-18-34-32(37)31-30-16-15-29(39-22-26-11-7-5-8-12-26)21-28(30)17-19-36(31)33(38)40-23-27-13-9-6-10-14-27/h5-16,21,24-25,31H,17-20,22-23H2,1-4H3,(H,34,37) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 27 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410121
(CHEMBL182158)Show SMILES CSc1ccc(Oc2ccc3C(N(CCc3c2)C(=O)OC(C)(C)C)C(=O)NCCN(C(C)C)C(C)C)cc1 Show InChI InChI=1S/C30H43N3O4S/c1-20(2)32(21(3)4)18-16-31-28(34)27-26-14-11-24(36-23-9-12-25(38-8)13-10-23)19-22(26)15-17-33(27)29(35)37-30(5,6)7/h9-14,19-21,27H,15-18H2,1-8H3,(H,31,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410122
(CHEMBL181156)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(OCc3ccccc3)ccc12)C(=O)C(O)c1ccccc1)C(C)C Show InChI InChI=1S/C33H41N3O4/c1-23(2)35(24(3)4)20-18-34-32(38)30-29-16-15-28(40-22-25-11-7-5-8-12-25)21-27(29)17-19-36(30)33(39)31(37)26-13-9-6-10-14-26/h5-16,21,23-24,30-31,37H,17-20,22H2,1-4H3,(H,34,38) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 39 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410127
(CHEMBL181735)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(OCc3ccccc3)ccc12)C(=O)OC1CCCCC1)C(C)C Show InChI InChI=1S/C32H45N3O4/c1-23(2)34(24(3)4)20-18-33-31(36)30-29-16-15-28(38-22-25-11-7-5-8-12-25)21-26(29)17-19-35(30)32(37)39-27-13-9-6-10-14-27/h5,7-8,11-12,15-16,21,23-24,27,30H,6,9-10,13-14,17-20,22H2,1-4H3,(H,33,36) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 4.90 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410130
(CHEMBL180093)Show SMILES CCCOC(=O)N1CCc2cc(OCc3ccccc3)ccc2C1C(=O)NCCN(C(C)C)C(C)C Show InChI InChI=1S/C29H41N3O4/c1-6-18-35-29(34)32-16-14-24-19-25(36-20-23-10-8-7-9-11-23)12-13-26(24)27(32)28(33)30-15-17-31(21(2)3)22(4)5/h7-13,19,21-22,27H,6,14-18,20H2,1-5H3,(H,30,33) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 3.40 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410133
(CHEMBL181063)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(Oc3cccc(c3)C(F)(F)F)ccc12)C(=O)OC(C)(C)C)C(C)C Show InChI InChI=1S/C30H40F3N3O4/c1-19(2)35(20(3)4)16-14-34-27(37)26-25-12-11-24(39-23-10-8-9-22(18-23)30(31,32)33)17-21(25)13-15-36(26)28(38)40-29(5,6)7/h8-12,17-20,26H,13-16H2,1-7H3,(H,34,37) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410141
(CHEMBL361802)Show SMILES COc1ccc(CC(=O)N2CCc3cc(OCc4ccccc4)ccc3C2C(=O)NCCN(C(C)C)C(C)C)cc1 Show InChI InChI=1S/C34H43N3O4/c1-24(2)36(25(3)4)20-18-35-34(39)33-31-16-15-30(41-23-27-9-7-6-8-10-27)22-28(31)17-19-37(33)32(38)21-26-11-13-29(40-5)14-12-26/h6-16,22,24-25,33H,17-21,23H2,1-5H3,(H,35,39) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 45 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410123
(CHEMBL180094)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(Oc3ccccc3)ccc12)C(=O)OC(C)(C)C)C(C)C Show InChI InChI=1S/C29H41N3O4/c1-20(2)31(21(3)4)18-16-30-27(33)26-25-14-13-24(35-23-11-9-8-10-12-23)19-22(25)15-17-32(26)28(34)36-29(5,6)7/h8-14,19-21,26H,15-18H2,1-7H3,(H,30,33) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.490 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410123
(CHEMBL180094)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(Oc3ccccc3)ccc12)C(=O)OC(C)(C)C)C(C)C Show InChI InChI=1S/C29H41N3O4/c1-20(2)31(21(3)4)18-16-30-27(33)26-25-14-13-24(35-23-11-9-8-10-12-23)19-22(25)15-17-32(26)28(34)36-29(5,6)7/h8-14,19-21,26H,15-18H2,1-7H3,(H,30,33) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.460 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410105
(CHEMBL359686)Show SMILES COc1cccc(CC(=O)N2CCc3cc(OCc4ccccc4)ccc3C2C(=O)NCCN(C(C)C)C(C)C)c1 Show InChI InChI=1S/C34H43N3O4/c1-24(2)36(25(3)4)19-17-35-34(39)33-31-15-14-30(41-23-26-10-7-6-8-11-26)22-28(31)16-18-37(33)32(38)21-27-12-9-13-29(20-27)40-5/h6-15,20,22,24-25,33H,16-19,21,23H2,1-5H3,(H,35,39) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 6.40 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410108
(CHEMBL179823)Show SMILES COc1cccc(Oc2ccc3C(N(CCc3c2)C(=O)OC(C)(C)C)C(=O)NCCN(C(C)C)C(C)C)c1 Show InChI InChI=1S/C30H43N3O5/c1-20(2)32(21(3)4)17-15-31-28(34)27-26-13-12-25(37-24-11-9-10-23(19-24)36-8)18-22(26)14-16-33(27)29(35)38-30(5,6)7/h9-13,18-21,27H,14-17H2,1-8H3,(H,31,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.460 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410119
(CHEMBL182137)Show SMILES CCN(CC)CCNC(=O)C1N(CCc2cc(OCc3ccccc3)ccc12)C(=O)OC(C)(C)C Show InChI InChI=1S/C28H39N3O4/c1-6-30(7-2)18-16-29-26(32)25-24-14-13-23(34-20-21-11-9-8-10-12-21)19-22(24)15-17-31(25)27(33)35-28(3,4)5/h8-14,19,25H,6-7,15-18,20H2,1-5H3,(H,29,32) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 19.6 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410142
(CHEMBL360891)Show SMILES CC(C)N(C)CCNC(=O)C1N(CCc2cc(OCc3ccccc3)ccc12)C(=O)OC(C)(C)C Show InChI InChI=1S/C28H39N3O4/c1-20(2)30(6)17-15-29-26(32)25-24-13-12-23(34-19-21-10-8-7-9-11-21)18-22(24)14-16-31(25)27(33)35-28(3,4)5/h7-13,18,20,25H,14-17,19H2,1-6H3,(H,29,32) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 41 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410106
(CHEMBL181337)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(OCc3ccccc3)ccc12)C(=O)S(=O)(=O)N(C)C)C(C)C Show InChI InChI=1S/C28H40N4O5S/c1-20(2)31(21(3)4)17-15-29-27(33)26-25-13-12-24(37-19-22-10-8-7-9-11-22)18-23(25)14-16-32(26)28(34)38(35,36)30(5)6/h7-13,18,20-21,26H,14-17,19H2,1-6H3,(H,29,33) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 21 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410109
(CHEMBL361612)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(OCc3ccccc3)ccc12)C(=O)c1ccccc1F)C(C)C Show InChI InChI=1S/C32H38FN3O3/c1-22(2)35(23(3)4)19-17-34-31(37)30-27-15-14-26(39-21-24-10-6-5-7-11-24)20-25(27)16-18-36(30)32(38)28-12-8-9-13-29(28)33/h5-15,20,22-23,30H,16-19,21H2,1-4H3,(H,34,37) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 17.8 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410111
(CHEMBL362798)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(OCc3ccccc3)ccc12)C(=O)CC(C)(C)C)C(C)C Show InChI InChI=1S/C31H45N3O3/c1-22(2)33(23(3)4)18-16-32-30(36)29-27-14-13-26(37-21-24-11-9-8-10-12-24)19-25(27)15-17-34(29)28(35)20-31(5,6)7/h8-14,19,22-23,29H,15-18,20-21H2,1-7H3,(H,32,36) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 20.9 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410113
(CHEMBL181832)Show SMILES COc1ccccc1CC(=O)N1CCc2cc(OCc3ccccc3)ccc2C1C(=O)NCCN(C(C)C)C(C)C Show InChI InChI=1S/C34H43N3O4/c1-24(2)36(25(3)4)20-18-35-34(39)33-30-16-15-29(41-23-26-11-7-6-8-12-26)21-27(30)17-19-37(33)32(38)22-28-13-9-10-14-31(28)40-5/h6-16,21,24-25,33H,17-20,22-23H2,1-5H3,(H,35,39) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410117
(CHEMBL182136)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(OCc3ccccc3)ccc12)C(=O)N(C)C)C(C)C Show InChI InChI=1S/C28H40N4O3/c1-20(2)31(21(3)4)17-15-29-27(33)26-25-13-12-24(35-19-22-10-8-7-9-11-22)18-23(25)14-16-32(26)28(34)30(5)6/h7-13,18,20-21,26H,14-17,19H2,1-6H3,(H,29,33) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 190 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410124
(CHEMBL179785)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(OCc3ccccc3)ccc12)C(=O)OC(C)(C)C(=O)N(C)C)C(C)C Show InChI InChI=1S/C32H46N4O5/c1-22(2)35(23(3)4)19-17-33-29(37)28-27-15-14-26(40-21-24-12-10-9-11-13-24)20-25(27)16-18-36(28)31(39)41-32(5,6)30(38)34(7)8/h9-15,20,22-23,28H,16-19,21H2,1-8H3,(H,33,37) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.850 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410125
(CHEMBL180591)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(OCc3ccccc3)ccc12)C(=O)OC(C)(C)C#N)C(C)C Show InChI InChI=1S/C30H40N4O4/c1-21(2)33(22(3)4)17-15-32-28(35)27-26-13-12-25(37-19-23-10-8-7-9-11-23)18-24(26)14-16-34(27)29(36)38-30(5,6)20-31/h7-13,18,21-22,27H,14-17,19H2,1-6H3,(H,32,35) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 9.80 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410137
(CHEMBL181051)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(OCc3ccccc3)ccc12)C(C)=O)C(C)C Show InChI InChI=1S/C27H37N3O3/c1-19(2)29(20(3)4)16-14-28-27(32)26-25-12-11-24(33-18-22-9-7-6-8-10-22)17-23(25)13-15-30(26)21(5)31/h6-12,17,19-20,26H,13-16,18H2,1-5H3,(H,28,32) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 257 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410143
(CHEMBL181092)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(OCc3ccccc3)ccc12)C(=O)OC(C)(C)C)C(C)C Show InChI InChI=1S/C30H43N3O4/c1-21(2)32(22(3)4)18-16-31-28(34)27-26-14-13-25(36-20-23-11-9-8-10-12-23)19-24(26)15-17-33(27)29(35)37-30(5,6)7/h8-14,19,21-22,27H,15-18,20H2,1-7H3,(H,31,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 11.7 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410144
(CHEMBL181247)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(OCc3ccccc3)ccc12)C(=O)NC(C)(C)C)C(C)C Show InChI InChI=1S/C30H44N4O3/c1-21(2)33(22(3)4)18-16-31-28(35)27-26-14-13-25(37-20-23-11-9-8-10-12-23)19-24(26)15-17-34(27)29(36)32-30(5,6)7/h8-14,19,21-22,27H,15-18,20H2,1-7H3,(H,31,35)(H,32,36) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 14.4 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410145
(CHEMBL180659)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(OCc3ccccc3)ccc12)C(=O)OC(C)(C)C(C)=O)C(C)C Show InChI InChI=1S/C31H43N3O5/c1-21(2)33(22(3)4)18-16-32-29(36)28-27-14-13-26(38-20-24-11-9-8-10-12-24)19-25(27)15-17-34(28)30(37)39-31(6,7)23(5)35/h8-14,19,21-22,28H,15-18,20H2,1-7H3,(H,32,36) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vivo effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410146
(CHEMBL181352)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(OCc3ccccc3)ccc12)C(=O)S(=O)(=O)c1ccccc1)C(C)C Show InChI InChI=1S/C32H39N3O5S/c1-23(2)34(24(3)4)20-18-33-31(36)30-29-16-15-27(40-22-25-11-7-5-8-12-25)21-26(29)17-19-35(30)32(37)41(38,39)28-13-9-6-10-14-28/h5-16,21,23-24,30H,17-20,22H2,1-4H3,(H,33,36) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 21 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50366689
(GHRELIN)Show SMILES CCCCCCCC(=O)OC[C@H](NC(=O)CNC(=O)[C@@H](N)CCCN=C(N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(O)=O |r,wU:65.67,185.189,192.197,230.236,120.122,11.11,69.70,129.131,19.19,164.166,37.36,173.175,201.205,48.48,218.222,111.113,56.56,wD:106.109,196.201,31.30,140.142,78.79,149.151,158.160,88.90,97.99,210.214,(-10.37,-25.43,;-9.06,-26.25,;-7.69,-25.54,;-6.4,-26.34,;-5.04,-25.62,;-3.72,-26.44,;-2.37,-25.72,;-2.31,-24.18,;-3.63,-23.36,;-.95,-23.47,;-.89,-21.92,;.45,-21.2,;1.74,-22.05,;1.71,-23.59,;.35,-24.3,;3.02,-24.41,;2.96,-25.94,;4.26,-26.76,;5.62,-26.03,;4.21,-28.3,;5.52,-29.12,;2.86,-29.01,;1.55,-28.21,;.19,-28.92,;-1.13,-28.13,;-2.49,-28.84,;-2.56,-30.38,;-3.82,-28.04,;.51,-19.67,;1.87,-18.94,;-.8,-18.87,;-.72,-17.33,;.63,-16.62,;.68,-15.08,;-2.02,-16.52,;-3.39,-17.24,;-1.98,-14.98,;-3.28,-14.16,;-4.66,-14.88,;-5.95,-14.06,;-7.3,-14.78,;-8.59,-13.97,;-8.55,-12.43,;-7.19,-11.7,;-5.88,-12.51,;-3.24,-12.62,;-4.54,-11.8,;-1.88,-11.9,;-1.81,-10.36,;-3.12,-9.54,;-3.06,-8,;-4.37,-7.19,;-1.71,-7.28,;-.46,-9.64,;.85,-10.45,;-.4,-8.1,;.96,-7.38,;1.01,-5.83,;-.31,-5.04,;2.26,-8.19,;1.95,-9.69,;3.72,-7.72,;4.22,-6.25,;5.76,-6.25,;6.23,-7.71,;4.98,-8.61,;4.98,-10.16,;3.64,-10.92,;6.3,-10.95,;7.63,-10.18,;7.63,-8.64,;8.96,-7.87,;8.96,-6.33,;10.28,-5.58,;7.63,-5.56,;8.96,-10.94,;10.3,-10.18,;8.94,-12.48,;7.6,-13.24,;6.26,-12.47,;4.93,-13.24,;3.52,-12.6,;2.48,-13.74,;3.25,-15.07,;4.76,-14.77,;7.6,-14.78,;8.93,-15.55,;6.27,-15.55,;6.27,-17.09,;4.93,-17.86,;4.93,-19.4,;3.6,-20.17,;2.27,-19.41,;3.6,-21.71,;7.6,-17.86,;7.6,-19.4,;8.93,-17.09,;10.27,-17.85,;10.27,-19.39,;11.62,-20.16,;11.62,-21.7,;12.94,-22.47,;12.93,-24.02,;11.62,-17.08,;12.94,-17.85,;11.61,-15.54,;12.94,-14.77,;14.28,-15.54,;12.94,-13.23,;11.61,-12.47,;14.27,-12.46,;14.28,-10.92,;12.95,-10.16,;12.95,-8.61,;11.61,-7.85,;10.24,-8.64,;11.61,-6.3,;15.6,-10.16,;16.95,-10.92,;15.56,-8.62,;16.9,-7.85,;16.9,-6.31,;15.56,-5.54,;15.56,-4,;16.85,-3.26,;14.22,-3.23,;18.23,-8.62,;18.23,-10.16,;19.57,-7.86,;20.92,-8.59,;22.25,-7.82,;22.25,-6.28,;23.59,-5.51,;24.89,-6.32,;26.21,-5.53,;27.53,-6.34,;26.19,-4.02,;20.92,-10.13,;19.58,-10.9,;22.23,-10.94,;22.26,-12.48,;20.93,-13.26,;20.93,-14.79,;19.59,-15.57,;18.26,-14.79,;18.23,-13.29,;23.59,-13.26,;23.59,-14.79,;24.93,-12.49,;26.28,-13.23,;26.28,-14.77,;27.62,-15.54,;27.62,-17.08,;26.27,-17.86,;28.95,-17.85,;27.62,-12.46,;27.62,-10.93,;28.94,-13.24,;30.27,-12.46,;31.6,-13.23,;32.93,-12.48,;30.27,-10.92,;28.94,-10.16,;31.61,-10.16,;31.62,-8.62,;30.29,-7.85,;30.29,-6.31,;28.95,-5.54,;28.95,-4,;27.61,-3.24,;32.95,-7.85,;34.28,-8.62,;32.94,-6.31,;34.27,-5.54,;34.27,-4,;32.94,-3.23,;32.94,-1.69,;31.61,-.92,;31.59,.62,;35.61,-6.31,;35.61,-7.85,;36.94,-5.54,;37.1,-4.04,;38.62,-3.7,;39.39,-5.03,;38.39,-6.18,;38.7,-7.66,;37.62,-8.74,;40.19,-8.15,;41.43,-7.23,;42.69,-8.12,;42.22,-9.6,;40.68,-9.6,;39.89,-10.92,;38.34,-10.89,;40.63,-12.27,;39.83,-13.59,;38.29,-13.57,;40.58,-14.95,;42.12,-14.97,;39.78,-16.26,;40.53,-17.61,;42.07,-17.63,;42.87,-16.31,;44.4,-16.34,;45.15,-17.69,;46.68,-17.73,;39.73,-18.92,;40.48,-20.27,;38.19,-18.9,;37.4,-20.22,;35.86,-20.19,;35.07,-21.51,;33.53,-21.48,;35.82,-22.85,;38.15,-21.56,;39.69,-21.6,;37.36,-22.88,;38.1,-24.23,;39.65,-24.27,;40.39,-25.61,;41.93,-25.64,;42.66,-26.99,;42.72,-24.32,;37.3,-25.55,;35.77,-25.52,;38.03,-26.89,;39.64,-27.11,;39.85,-28.64,;38.55,-29.35,;37.45,-28.32,;35.9,-28.61,;35.48,-30.09,;34.83,-27.5,)| Show InChI InChI=1S/C147H245N45O42/c1-8-9-10-11-15-45-118(205)234-78-106(169-115(200)74-165-121(208)86(153)34-26-63-163-146(158)159)138(225)187-104(76-194)137(224)184-101(71-84-32-13-12-14-33-84)134(221)183-100(70-81(4)5)133(220)188-105(77-195)143(230)189-65-28-42-108(189)140(227)179-96(51-57-117(203)204)130(217)185-102(72-85-73-162-79-166-85)135(222)178-94(48-54-113(156)198)129(216)172-87(35-16-21-58-148)122(209)167-82(6)119(206)171-92(46-52-111(154)196)127(214)176-93(47-53-112(155)197)128(215)174-91(40-27-64-164-147(160)161)124(211)173-89(37-18-23-60-150)123(210)177-95(50-56-116(201)202)131(218)186-103(75-193)136(223)175-90(38-19-24-61-151)125(212)180-97(39-20-25-62-152)141(228)191-67-30-43-109(191)144(231)190-66-29-41-107(190)139(226)168-83(7)120(207)170-88(36-17-22-59-149)126(213)182-99(69-80(2)3)132(219)181-98(49-55-114(157)199)142(229)192-68-31-44-110(192)145(232)233/h12-14,32-33,73,79-83,86-110,193-195H,8-11,15-31,34-72,74-78,148-153H2,1-7H3,(H2,154,196)(H2,155,197)(H2,156,198)(H2,157,199)(H,162,166)(H,165,208)(H,167,209)(H,168,226)(H,169,200)(H,170,207)(H,171,206)(H,172,216)(H,173,211)(H,174,215)(H,175,223)(H,176,214)(H,177,210)(H,178,222)(H,179,227)(H,180,212)(H,181,219)(H,182,213)(H,183,221)(H,184,224)(H,185,217)(H,186,218)(H,187,225)(H,188,220)(H,201,202)(H,203,204)(H,232,233)(H4,158,159,163)(H4,160,161,164)/t82-,83-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410126
(CHEMBL178216)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(OCc3ccccc3)ccc12)C(=O)C(CO)c1ccccc1)C(C)C Show InChI InChI=1S/C34H43N3O4/c1-24(2)36(25(3)4)20-18-35-33(39)32-30-16-15-29(41-23-26-11-7-5-8-12-26)21-28(30)17-19-37(32)34(40)31(22-38)27-13-9-6-10-14-27/h5-16,21,24-25,31-32,38H,17-20,22-23H2,1-4H3,(H,35,39) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 5.60 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410131
(CHEMBL178900)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(Oc3ccc(Cl)cc3)ccc12)C(=O)OC(C)(C)C)C(C)C Show InChI InChI=1S/C29H40ClN3O4/c1-19(2)32(20(3)4)17-15-31-27(34)26-25-13-12-24(36-23-10-8-22(30)9-11-23)18-21(25)14-16-33(26)28(35)37-29(5,6)7/h8-13,18-20,26H,14-17H2,1-7H3,(H,31,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.730 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410134
(CHEMBL360877)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(OCc3ccccc3)ccc12)C(=O)C(C)c1ccccc1)C(C)C Show InChI InChI=1S/C34H43N3O3/c1-24(2)36(25(3)4)21-19-35-33(38)32-31-17-16-30(40-23-27-12-8-6-9-13-27)22-29(31)18-20-37(32)34(39)26(5)28-14-10-7-11-15-28/h6-17,22,24-26,32H,18-21,23H2,1-5H3,(H,35,38) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 3.40 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410136
(CHEMBL179978)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(OCc3ccccc3)ccc12)C(=O)c1ccccc1C(C)=O)C(C)C Show InChI InChI=1S/C34H41N3O4/c1-23(2)36(24(3)4)20-18-35-33(39)32-30-16-15-28(41-22-26-11-7-6-8-12-26)21-27(30)17-19-37(32)34(40)31-14-10-9-13-29(31)25(5)38/h6-16,21,23-24,32H,17-20,22H2,1-5H3,(H,35,39) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 7.30 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410104
(CHEMBL181764)Show SMILES COC(=O)C(C)(C)OC(=O)N1CCc2cc(OCc3ccccc3)ccc2C1C(=O)NCCN(C(C)C)C(C)C Show InChI InChI=1S/C31H43N3O6/c1-21(2)33(22(3)4)18-16-32-28(35)27-26-14-13-25(39-20-23-11-9-8-10-12-23)19-24(26)15-17-34(27)30(37)40-31(5,6)29(36)38-7/h8-14,19,21-22,27H,15-18,20H2,1-7H3,(H,32,35) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vivo effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410107
(CHEMBL181627)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(OCc3ccccc3)ccc12)C(=O)CCCc1ccccc1)C(C)C Show InChI InChI=1S/C35H45N3O3/c1-26(2)37(27(3)4)23-21-36-35(40)34-32-19-18-31(41-25-29-14-9-6-10-15-29)24-30(32)20-22-38(34)33(39)17-11-16-28-12-7-5-8-13-28/h5-10,12-15,18-19,24,26-27,34H,11,16-17,20-23,25H2,1-4H3,(H,36,40) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 13.1 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410114
(CHEMBL360547)Show SMILES COc1ccc(Oc2ccc3C(N(CCc3c2)C(=O)OC(C)(C)C)C(=O)NCCN(C(C)C)C(C)C)cc1 Show InChI InChI=1S/C30H43N3O5/c1-20(2)32(21(3)4)18-16-31-28(34)27-26-14-13-25(37-24-11-9-23(36-8)10-12-24)19-22(26)15-17-33(27)29(35)38-30(5,6)7/h9-14,19-21,27H,15-18H2,1-8H3,(H,31,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.490 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vivo effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410115
(CHEMBL182050)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(Oc3cccc(F)c3)ccc12)C(=O)OC(C)(C)C)C(C)C Show InChI InChI=1S/C29H40FN3O4/c1-19(2)32(20(3)4)16-14-31-27(34)26-25-12-11-24(36-23-10-8-9-22(30)18-23)17-21(25)13-15-33(26)28(35)37-29(5,6)7/h8-12,17-20,26H,13-16H2,1-7H3,(H,31,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410118
(CHEMBL181786)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(Oc3ccc(cc3)C(F)(F)F)ccc12)C(=O)OC(C)(C)C)C(C)C Show InChI InChI=1S/C30H40F3N3O4/c1-19(2)35(20(3)4)17-15-34-27(37)26-25-13-12-24(39-23-10-8-22(9-11-23)30(31,32)33)18-21(25)14-16-36(26)28(38)40-29(5,6)7/h8-13,18-20,26H,14-17H2,1-7H3,(H,34,37) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410129
(CHEMBL178502)Show SMILES CC(C)NCCNC(=O)C1N(CCc2cc(OCc3ccccc3)ccc12)C(=O)OC(C)(C)C Show InChI InChI=1S/C27H37N3O4/c1-19(2)28-14-15-29-25(31)24-23-12-11-22(33-18-20-9-7-6-8-10-20)17-21(23)13-16-30(24)26(32)34-27(3,4)5/h6-12,17,19,24,28H,13-16,18H2,1-5H3,(H,29,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 219 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410138
(CHEMBL180246)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(Oc3ccc(C=O)cc3)ccc12)C(=O)OC(C)(C)C)C(C)C Show InChI InChI=1S/C30H41N3O5/c1-20(2)32(21(3)4)17-15-31-28(35)27-26-13-12-25(37-24-10-8-22(19-34)9-11-24)18-23(26)14-16-33(27)29(36)38-30(5,6)7/h8-13,18-21,27H,14-17H2,1-7H3,(H,31,35) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410139
(CHEMBL369571)Show SMILES CC(C)(C)OC(=O)N1CCc2cc(OCc3ccccc3)ccc2C1C(=O)NCC(C)(C)CN Show InChI InChI=1S/C27H37N3O4/c1-26(2,3)34-25(32)30-14-13-20-15-21(33-16-19-9-7-6-8-10-19)11-12-22(20)23(30)24(31)29-18-27(4,5)17-28/h6-12,15,23H,13-14,16-18,28H2,1-5H3,(H,29,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 257 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410148
(CHEMBL360247)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(OCc3ccccc3)ccc12)C(=O)Cc1ccccc1F)C(C)C Show InChI InChI=1S/C33H40FN3O3/c1-23(2)36(24(3)4)19-17-35-33(39)32-29-15-14-28(40-22-25-10-6-5-7-11-25)20-26(29)16-18-37(32)31(38)21-27-12-8-9-13-30(27)34/h5-15,20,23-24,32H,16-19,21-22H2,1-4H3,(H,35,39) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 43 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410147
(CHEMBL180992)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(OCc3ccccc3)ccc12)C(=O)Cc1ccccc1)C(C)C Show InChI InChI=1S/C33H41N3O3/c1-24(2)35(25(3)4)20-18-34-33(38)32-30-16-15-29(39-23-27-13-9-6-10-14-27)22-28(30)17-19-36(32)31(37)21-26-11-7-5-8-12-26/h5-16,22,24-25,32H,17-21,23H2,1-4H3,(H,34,38) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 9 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410145
(CHEMBL180659)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(OCc3ccccc3)ccc12)C(=O)OC(C)(C)C(C)=O)C(C)C Show InChI InChI=1S/C31H43N3O5/c1-21(2)33(22(3)4)18-16-32-29(36)28-27-14-13-26(38-20-24-11-9-8-10-12-24)19-25(27)15-17-34(28)30(37)39-31(6,7)23(5)35/h8-14,19,21-22,28H,15-18,20H2,1-7H3,(H,32,36) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410110
(CHEMBL180540)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(OCc3ccccc3)ccc12)C(=O)c1ccccc1)C(C)C Show InChI InChI=1S/C32H39N3O3/c1-23(2)34(24(3)4)20-18-33-31(36)30-29-16-15-28(38-22-25-11-7-5-8-12-25)21-27(29)17-19-35(30)32(37)26-13-9-6-10-14-26/h5-16,21,23-24,30H,17-20,22H2,1-4H3,(H,33,36) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 7.60 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410123
(CHEMBL180094)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(Oc3ccccc3)ccc12)C(=O)OC(C)(C)C)C(C)C Show InChI InChI=1S/C29H41N3O4/c1-20(2)31(21(3)4)18-16-30-27(33)26-25-14-13-24(35-23-11-9-8-10-12-23)19-22(25)15-17-32(26)28(34)36-29(5,6)7/h8-14,19-21,26H,15-18H2,1-7H3,(H,30,33) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.460 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vivo effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410135
(CHEMBL369329)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(Oc3cccc(c3)[N+]([O-])=O)ccc12)C(=O)OC(C)(C)C)C(C)C Show InChI InChI=1S/C29H40N4O6/c1-19(2)31(20(3)4)16-14-30-27(34)26-25-12-11-24(38-23-10-8-9-22(18-23)33(36)37)17-21(25)13-15-32(26)28(35)39-29(5,6)7/h8-12,17-20,26H,13-16H2,1-7H3,(H,30,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.660 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410123
(CHEMBL180094)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(Oc3ccccc3)ccc12)C(=O)OC(C)(C)C)C(C)C Show InChI InChI=1S/C29H41N3O4/c1-20(2)31(21(3)4)18-16-30-27(33)26-25-14-13-24(35-23-11-9-8-10-12-23)19-22(25)15-17-32(26)28(34)36-29(5,6)7/h8-14,19-21,26H,15-18H2,1-7H3,(H,30,33) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.490 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50410120
(CHEMBL366916)Show SMILES CC(C)N(CCNC(=O)C1N(CCc2cc(OCc3ccccc3)ccc12)C(=O)CCc1ccccc1)C(C)C Show InChI InChI=1S/C34H43N3O3/c1-25(2)36(26(3)4)22-20-35-34(39)33-31-17-16-30(40-24-28-13-9-6-10-14-28)23-29(31)19-21-37(33)32(38)18-15-27-11-7-5-8-12-27/h5-14,16-17,23,25-26,33H,15,18-22,24H2,1-4H3,(H,35,39) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 26.7 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
In vitro effective concentration against human growth hormone secretagogues |
Bioorg Med Chem Lett 15: 1799-802 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.040
BindingDB Entry DOI: 10.7270/Q21837Q4 |
More data for this
Ligand-Target Pair | |
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