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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM15186 (4-(5-{[(5E)-2-amino-3,7-dicyano-4,6-dimethyl-5H-cy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet  | PC cid PC sid UniChem Patents Similars | Article PubMed | 1.10E+3 | -34.0 | 2.60E+3 | n/a | n/a | n/a | n/a | 7.5 | 25 |
The Burnham Institute | Assay Description The Z-LYTE assay (Invitrogen Corporation) employs a FRET-based, coupled-enzyme format and is based on the differential sensitivity of phosphorylated ... | J Med Chem 48: 2278-81 (2005) Article DOI: 10.1021/jm048962u BindingDB Entry DOI: 10.7270/Q2KD1W4Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM15187 (3-[(2E)-3-(1H-1,3-benzodiazol-2-yl)prop-2-enoyl]-6...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents | Article PubMed | 3.90E+3 | -30.9 | 4.50E+3 | n/a | n/a | n/a | n/a | 7.5 | 25 |
The Burnham Institute | Assay Description The Z-LYTE assay (Invitrogen Corporation) employs a FRET-based, coupled-enzyme format and is based on the differential sensitivity of phosphorylated ... | J Med Chem 48: 2278-81 (2005) Article DOI: 10.1021/jm048962u BindingDB Entry DOI: 10.7270/Q2KD1W4Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM15188 (5-{5-[(1,3-dioxo-2,3-dihydro-1H-inden-2-ylidene)me...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.08E+4 | -26.7 | 2.51E+4 | n/a | n/a | n/a | n/a | 7.5 | 25 |
The Burnham Institute | Assay Description The Z-LYTE assay (Invitrogen Corporation) employs a FRET-based, coupled-enzyme format and is based on the differential sensitivity of phosphorylated ... | J Med Chem 48: 2278-81 (2005) Article DOI: 10.1021/jm048962u BindingDB Entry DOI: 10.7270/Q2KD1W4Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM15190 (3-(5-{[(5E)-2-amino-3,7-dicyano-4,6-dimethyl-5H-cy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.02E+4 | n/a | n/a | n/a | n/a | 7.5 | 25 |
The Burnham Institute | Assay Description The Z-LYTE assay (Invitrogen Corporation) employs a FRET-based, coupled-enzyme format and is based on the differential sensitivity of phosphorylated ... | J Med Chem 48: 2278-81 (2005) Article DOI: 10.1021/jm048962u BindingDB Entry DOI: 10.7270/Q2KD1W4Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM15189 (4-(5-{[(5E)-2-amino-3,7-dicyano-4,6-dimethyl-5H-cy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.26E+5 | n/a | n/a | n/a | n/a | 7.5 | 25 |
The Burnham Institute | Assay Description The Z-LYTE assay (Invitrogen Corporation) employs a FRET-based, coupled-enzyme format and is based on the differential sensitivity of phosphorylated ... | J Med Chem 48: 2278-81 (2005) Article DOI: 10.1021/jm048962u BindingDB Entry DOI: 10.7270/Q2KD1W4Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
