BindingDB logo
myBDB logout

PubMed code 15808469

Compile data set for download or QSAR
Found 32 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA topoisomerase 1


(Homo sapiens (Human))		BDBM50410165
PNG
(CHEMBL372661)
Show SMILES Oc1ccc2OC(=O)\C(=C\c3cc(O)c(O)c(O)c3)c2c1
Show InChI InChI=1S/C15H10O6/c16-8-1-2-13-9(6-8)10(15(20)21-13)3-7-4-11(17)14(19)12(18)5-7/h1-6,16-19H/b10-3+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.00E+3n/an/an/an/an/an/a



Kumamoto University

Curated by ChEMBL


Assay Description
Inhibitory concentration against DNA topoisomerase I activity

Bioorg Med Chem Lett 15: 2065-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.052
BindingDB Entry DOI: 10.7270/Q2WH2R6D
More data for this
Ligand-Target Pair
DNA topoisomerase 1


(Homo sapiens (Human))		BDBM50410153
PNG
(CHEMBL197216)
Show SMILES Oc1cc(\C=C2\C(=O)Oc3ccccc23)cc(O)c1O
Show InChI InChI=1S/C15H10O5/c16-11-6-8(7-12(17)14(11)18)5-10-9-3-1-2-4-13(9)20-15(10)19/h1-7,16-18H/b10-5+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 4.00E+3n/an/an/an/an/an/a



Kumamoto University

Curated by ChEMBL


Assay Description
Inhibitory concentration against DNA topoisomerase I activity

Bioorg Med Chem Lett 15: 2065-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.052
BindingDB Entry DOI: 10.7270/Q2WH2R6D
More data for this
Ligand-Target Pair
DNA topoisomerase 1


(Homo sapiens (Human))		BDBM50410158
PNG
(CHEMBL195195)
Show SMILES Oc1ccc2OC(=O)\C(=C\c3ccc(O)c(O)c3)c2c1
Show InChI InChI=1S/C15H10O5/c16-9-2-4-14-10(7-9)11(15(19)20-14)5-8-1-3-12(17)13(18)6-8/h1-7,16-18H/b11-5+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 6.00E+3n/an/an/an/an/an/a



Kumamoto University

Curated by ChEMBL


Assay Description
Inhibitory concentration against DNA topoisomerase I activity

Bioorg Med Chem Lett 15: 2065-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.052
BindingDB Entry DOI: 10.7270/Q2WH2R6D
More data for this
Ligand-Target Pair
DNA topoisomerase 2-alpha


(Homo sapiens (Human))		BDBM50410153
PNG
(CHEMBL197216)
Show SMILES Oc1cc(\C=C2\C(=O)Oc3ccccc23)cc(O)c1O
Show InChI InChI=1S/C15H10O5/c16-11-6-8(7-12(17)14(11)18)5-10-9-3-1-2-4-13(9)20-15(10)19/h1-7,16-18H/b10-5+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 6.30E+4n/an/an/an/an/an/a



Kumamoto University

Curated by ChEMBL


Assay Description
Inhibitory concentration against DNA topoisomerase II activity

Bioorg Med Chem Lett 15: 2065-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.052
BindingDB Entry DOI: 10.7270/Q2WH2R6D
More data for this
Ligand-Target Pair
DNA topoisomerase 2-alpha


(Homo sapiens (Human))		BDBM50410165
PNG
(CHEMBL372661)
Show SMILES Oc1ccc2OC(=O)\C(=C\c3cc(O)c(O)c(O)c3)c2c1
Show InChI InChI=1S/C15H10O6/c16-8-1-2-13-9(6-8)10(15(20)21-13)3-7-4-11(17)14(19)12(18)5-7/h1-6,16-19H/b10-3+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.20E+5n/an/an/an/an/an/a



Kumamoto University

Curated by ChEMBL


Assay Description
Inhibitory concentration against DNA topoisomerase II activity

Bioorg Med Chem Lett 15: 2065-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.052
BindingDB Entry DOI: 10.7270/Q2WH2R6D
More data for this
Ligand-Target Pair
DNA topoisomerase 1


(Homo sapiens (Human))		BDBM50410154
PNG
(CHEMBL370969)
Show SMILES [O-][N+](=O)c1ccc(\C=C2\C(=O)Oc3ccccc23)cc1
Show InChI InChI=1S/C15H9NO4/c17-15-13(12-3-1-2-4-14(12)20-15)9-10-5-7-11(8-6-10)16(18)19/h1-9H/b13-9+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.20E+5n/an/an/an/an/an/a



Kumamoto University

Curated by ChEMBL


Assay Description
Inhibitory concentration against DNA topoisomerase I activity

Bioorg Med Chem Lett 15: 2065-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.052
BindingDB Entry DOI: 10.7270/Q2WH2R6D
More data for this
Ligand-Target Pair
DNA topoisomerase 1


(Homo sapiens (Human))		BDBM50410156
PNG
(CHEMBL195143)
Show SMILES Oc1ccc(\C=C2\C(=O)Oc3ccccc23)cc1O
Show InChI InChI=1S/C15H10O4/c16-12-6-5-9(8-13(12)17)7-11-10-3-1-2-4-14(10)19-15(11)18/h1-8,16-17H/b11-7+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.60E+5n/an/an/an/an/an/a



Kumamoto University

Curated by ChEMBL


Assay Description
Inhibitory concentration against DNA topoisomerase I activity

Bioorg Med Chem Lett 15: 2065-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.052
BindingDB Entry DOI: 10.7270/Q2WH2R6D
More data for this
Ligand-Target Pair
DNA topoisomerase 2-alpha


(Homo sapiens (Human))		BDBM50410158
PNG
(CHEMBL195195)
Show SMILES Oc1ccc2OC(=O)\C(=C\c3ccc(O)c(O)c3)c2c1
Show InChI InChI=1S/C15H10O5/c16-9-2-4-14-10(7-9)11(15(19)20-14)5-8-1-3-12(17)13(18)6-8/h1-7,16-18H/b11-5+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.40E+5n/an/an/an/an/an/a



Kumamoto University

Curated by ChEMBL


Assay Description
Inhibitory concentration against DNA topoisomerase II activity

Bioorg Med Chem Lett 15: 2065-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.052
BindingDB Entry DOI: 10.7270/Q2WH2R6D
More data for this
Ligand-Target Pair
DNA topoisomerase 1


(Homo sapiens (Human))		BDBM50410152
PNG
(CHEMBL371047)
Show SMILES Oc1ccc(\C=C2\C(=O)Oc3ccccc23)cc1
Show InChI InChI=1S/C15H10O3/c16-11-7-5-10(6-8-11)9-13-12-3-1-2-4-14(12)18-15(13)17/h1-9,16H/b13-9+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.50E+5n/an/an/an/an/an/a



Kumamoto University

Curated by ChEMBL


Assay Description
Inhibitory concentration against DNA topoisomerase I activity

Bioorg Med Chem Lett 15: 2065-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.052
BindingDB Entry DOI: 10.7270/Q2WH2R6D
More data for this
Ligand-Target Pair
DNA topoisomerase 1


(Homo sapiens (Human))		BDBM50410164
PNG
(CHEMBL194829)
Show SMILES Oc1cccc(\C=C2\C(=O)Oc3ccccc23)c1
Show InChI InChI=1S/C15H10O3/c16-11-5-3-4-10(8-11)9-13-12-6-1-2-7-14(12)18-15(13)17/h1-9,16H/b13-9+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.62E+5n/an/an/an/an/an/a



Kumamoto University

Curated by ChEMBL


Assay Description
Inhibitory concentration against DNA topoisomerase I activity

Bioorg Med Chem Lett 15: 2065-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.052
BindingDB Entry DOI: 10.7270/Q2WH2R6D
More data for this
Ligand-Target Pair
DNA topoisomerase 2-alpha


(Homo sapiens (Human))		BDBM50410156
PNG
(CHEMBL195143)
Show SMILES Oc1ccc(\C=C2\C(=O)Oc3ccccc23)cc1O
Show InChI InChI=1S/C15H10O4/c16-12-6-5-9(8-13(12)17)7-11-10-3-1-2-4-14(10)19-15(11)18/h1-8,16-17H/b11-7+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.72E+5n/an/an/an/an/an/a



Kumamoto University

Curated by ChEMBL


Assay Description
Inhibitory concentration against DNA topoisomerase II activity

Bioorg Med Chem Lett 15: 2065-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.052
BindingDB Entry DOI: 10.7270/Q2WH2R6D
More data for this
Ligand-Target Pair
DNA topoisomerase 1


(Homo sapiens (Human))		BDBM50164888
PNG
(6-Hydroxy-3-[1-(4-hydroxy-phenyl)-meth-(E)-ylidene...)
Show SMILES Oc1ccc(\C=C2\C(=O)Oc3cc(O)ccc23)cc1
Show InChI InChI=1S/C15H10O4/c16-10-3-1-9(2-4-10)7-13-12-6-5-11(17)8-14(12)19-15(13)18/h1-8,16-17H/b13-7+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.07E+5n/an/an/an/an/an/a



Kumamoto University

Curated by ChEMBL


Assay Description
Inhibitory concentration against DNA topoisomerase I activity

Bioorg Med Chem Lett 15: 2065-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.052
BindingDB Entry DOI: 10.7270/Q2WH2R6D
More data for this
Ligand-Target Pair
DNA topoisomerase 2-alpha


(Homo sapiens (Human))		BDBM50410152
PNG
(CHEMBL371047)
Show SMILES Oc1ccc(\C=C2\C(=O)Oc3ccccc23)cc1
Show InChI InChI=1S/C15H10O3/c16-11-7-5-10(6-8-11)9-13-12-3-1-2-4-14(12)18-15(13)17/h1-9,16H/b13-9+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.27E+5n/an/an/an/an/an/a



Kumamoto University

Curated by ChEMBL


Assay Description
Inhibitory concentration against DNA topoisomerase II activity

Bioorg Med Chem Lett 15: 2065-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.052
BindingDB Entry DOI: 10.7270/Q2WH2R6D
More data for this
Ligand-Target Pair
DNA topoisomerase 2-alpha


(Homo sapiens (Human))		BDBM50410155
PNG
(CHEMBL372372)
Show SMILES COc1cc(\C=C2\C(=O)Oc3ccccc23)ccc1O
Show InChI InChI=1S/C16H12O4/c1-19-15-9-10(6-7-13(15)17)8-12-11-4-2-3-5-14(11)20-16(12)18/h2-9,17H,1H3/b12-8+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.51E+5n/an/an/an/an/an/a



Kumamoto University

Curated by ChEMBL


Assay Description
Inhibitory concentration against DNA topoisomerase II activity

Bioorg Med Chem Lett 15: 2065-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.052
BindingDB Entry DOI: 10.7270/Q2WH2R6D
More data for this
Ligand-Target Pair
DNA topoisomerase 1


(Homo sapiens (Human))		BDBM50410163
PNG
(CHEMBL364033)
Show SMILES Fc1ccc(\C=C2\C(=O)Oc3ccccc23)cc1
Show InChI InChI=1S/C15H9FO2/c16-11-7-5-10(6-8-11)9-13-12-3-1-2-4-14(12)18-15(13)17/h1-9H/b13-9+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.92E+5n/an/an/an/an/an/a



Kumamoto University

Curated by ChEMBL


Assay Description
Inhibitory concentration against DNA topoisomerase I activity

Bioorg Med Chem Lett 15: 2065-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.052
BindingDB Entry DOI: 10.7270/Q2WH2R6D
More data for this
Ligand-Target Pair
DNA topoisomerase 2-alpha


(Homo sapiens (Human))		BDBM50410157
PNG
(CHEMBL191658)
Show SMILES COc1ccc(\C=C2\C(=O)Oc3ccccc23)cc1
Show InChI InChI=1S/C16H12O3/c1-18-12-8-6-11(7-9-12)10-14-13-4-2-3-5-15(13)19-16(14)17/h2-10H,1H3/b14-10+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>4.00E+5n/an/an/an/an/an/a



Kumamoto University

Curated by ChEMBL


Assay Description
Inhibitory concentration against DNA topoisomerase II activity

Bioorg Med Chem Lett 15: 2065-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.052
BindingDB Entry DOI: 10.7270/Q2WH2R6D
More data for this
Ligand-Target Pair
DNA topoisomerase 2-alpha


(Homo sapiens (Human))		BDBM50164888
PNG
(6-Hydroxy-3-[1-(4-hydroxy-phenyl)-meth-(E)-ylidene...)
Show SMILES Oc1ccc(\C=C2\C(=O)Oc3cc(O)ccc23)cc1
Show InChI InChI=1S/C15H10O4/c16-10-3-1-9(2-4-10)7-13-12-6-5-11(17)8-14(12)19-15(13)18/h1-8,16-17H/b13-7+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>4.00E+5n/an/an/an/an/an/a



Kumamoto University

Curated by ChEMBL


Assay Description
Inhibitory concentration against DNA topoisomerase II activity

Bioorg Med Chem Lett 15: 2065-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.052
BindingDB Entry DOI: 10.7270/Q2WH2R6D
More data for this
Ligand-Target Pair
DNA topoisomerase 2-alpha


(Homo sapiens (Human))		BDBM50410160
PNG
(CHEMBL381195)
Show SMILES COc1ccc(\C=C2\C(=O)Oc3ccccc23)cc1O
Show InChI InChI=1S/C16H12O4/c1-19-15-7-6-10(9-13(15)17)8-12-11-4-2-3-5-14(11)20-16(12)18/h2-9,17H,1H3/b12-8+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>4.00E+5n/an/an/an/an/an/a



Kumamoto University

Curated by ChEMBL


Assay Description
Inhibitory concentration against DNA topoisomerase II activity

Bioorg Med Chem Lett 15: 2065-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.052
BindingDB Entry DOI: 10.7270/Q2WH2R6D
More data for this
Ligand-Target Pair
DNA topoisomerase 2-alpha


(Homo sapiens (Human))		BDBM50410163
PNG
(CHEMBL364033)
Show SMILES Fc1ccc(\C=C2\C(=O)Oc3ccccc23)cc1
Show InChI InChI=1S/C15H9FO2/c16-11-7-5-10(6-8-11)9-13-12-3-1-2-4-14(12)18-15(13)17/h1-9H/b13-9+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>4.00E+5n/an/an/an/an/an/a



Kumamoto University

Curated by ChEMBL


Assay Description
Inhibitory concentration against DNA topoisomerase II activity

Bioorg Med Chem Lett 15: 2065-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.052
BindingDB Entry DOI: 10.7270/Q2WH2R6D
More data for this
Ligand-Target Pair
DNA topoisomerase 2-alpha


(Homo sapiens (Human))		BDBM50410159
PNG
(CHEMBL426092)
Show SMILES Oc1ccc(\C=C2\C(=O)Oc3ccc(O)cc23)cc1
Show InChI InChI=1S/C15H10O4/c16-10-3-1-9(2-4-10)7-13-12-8-11(17)5-6-14(12)19-15(13)18/h1-8,16-17H/b13-7+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>4.00E+5n/an/an/an/an/an/a



Kumamoto University

Curated by ChEMBL


Assay Description
Inhibitory concentration against DNA topoisomerase II activity

Bioorg Med Chem Lett 15: 2065-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.052
BindingDB Entry DOI: 10.7270/Q2WH2R6D
More data for this
Ligand-Target Pair
DNA topoisomerase 2-alpha


(Homo sapiens (Human))		BDBM50410162
PNG
(CHEMBL193628)
Show SMILES CCOC(=O)Cc1ccc(\C=C2\C(=O)Oc3ccccc23)cc1
Show InChI InChI=1S/C19H16O4/c1-2-22-18(20)12-14-9-7-13(8-10-14)11-16-15-5-3-4-6-17(15)23-19(16)21/h3-11H,2,12H2,1H3/b16-11+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>4.00E+5n/an/an/an/an/an/a



Kumamoto University

Curated by ChEMBL


Assay Description
Inhibitory concentration against DNA topoisomerase II activity

Bioorg Med Chem Lett 15: 2065-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.052
BindingDB Entry DOI: 10.7270/Q2WH2R6D
More data for this
Ligand-Target Pair
DNA topoisomerase 2-alpha


(Homo sapiens (Human))		BDBM50410151
PNG
(CHEMBL381410)
Show SMILES Oc1ccc2OC(=O)\C(=C\c3ccccc3)c2c1
Show InChI InChI=1S/C15H10O3/c16-11-6-7-14-12(9-11)13(15(17)18-14)8-10-4-2-1-3-5-10/h1-9,16H/b13-8+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>4.00E+5n/an/an/an/an/an/a



Kumamoto University

Curated by ChEMBL


Assay Description
Inhibitory concentration against DNA topoisomerase II activity

Bioorg Med Chem Lett 15: 2065-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.052
BindingDB Entry DOI: 10.7270/Q2WH2R6D
More data for this
Ligand-Target Pair
DNA topoisomerase 2-alpha


(Homo sapiens (Human))		BDBM50410161
PNG
(CHEMBL191804)
Show SMILES O=C1Oc2ccccc2\C1=C/c1ccccc1
Show InChI InChI=1S/C15H10O2/c16-15-13(10-11-6-2-1-3-7-11)12-8-4-5-9-14(12)17-15/h1-10H/b13-10+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>4.00E+5n/an/an/an/an/an/a



Kumamoto University

Curated by ChEMBL


Assay Description
Inhibitory concentration against DNA topoisomerase II activity

Bioorg Med Chem Lett 15: 2065-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.052
BindingDB Entry DOI: 10.7270/Q2WH2R6D
More data for this
Ligand-Target Pair
DNA topoisomerase 2-alpha


(Homo sapiens (Human))		BDBM50410154
PNG
(CHEMBL370969)
Show SMILES [O-][N+](=O)c1ccc(\C=C2\C(=O)Oc3ccccc23)cc1
Show InChI InChI=1S/C15H9NO4/c17-15-13(12-3-1-2-4-14(12)20-15)9-10-5-7-11(8-6-10)16(18)19/h1-9H/b13-9+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>4.00E+5n/an/an/an/an/an/a



Kumamoto University

Curated by ChEMBL


Assay Description
Inhibitory concentration against DNA topoisomerase II activity

Bioorg Med Chem Lett 15: 2065-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.052
BindingDB Entry DOI: 10.7270/Q2WH2R6D
More data for this
Ligand-Target Pair
DNA topoisomerase 2-alpha


(Homo sapiens (Human))		BDBM50410164
PNG
(CHEMBL194829)
Show SMILES Oc1cccc(\C=C2\C(=O)Oc3ccccc23)c1
Show InChI InChI=1S/C15H10O3/c16-11-5-3-4-10(8-11)9-13-12-6-1-2-7-14(12)18-15(13)17/h1-9,16H/b13-9+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>4.00E+5n/an/an/an/an/an/a



Kumamoto University

Curated by ChEMBL


Assay Description
Inhibitory concentration against DNA topoisomerase II activity

Bioorg Med Chem Lett 15: 2065-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.052
BindingDB Entry DOI: 10.7270/Q2WH2R6D
More data for this
Ligand-Target Pair
DNA topoisomerase 1


(Homo sapiens (Human))		BDBM50410159
PNG
(CHEMBL426092)
Show SMILES Oc1ccc(\C=C2\C(=O)Oc3ccc(O)cc23)cc1
Show InChI InChI=1S/C15H10O4/c16-10-3-1-9(2-4-10)7-13-12-8-11(17)5-6-14(12)19-15(13)18/h1-8,16-17H/b13-7+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 5.55E+5n/an/an/an/an/an/a



Kumamoto University

Curated by ChEMBL


Assay Description
Inhibitory concentration against DNA topoisomerase I activity

Bioorg Med Chem Lett 15: 2065-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.052
BindingDB Entry DOI: 10.7270/Q2WH2R6D
More data for this
Ligand-Target Pair
DNA topoisomerase 1


(Homo sapiens (Human))		BDBM50410155
PNG
(CHEMBL372372)
Show SMILES COc1cc(\C=C2\C(=O)Oc3ccccc23)ccc1O
Show InChI InChI=1S/C16H12O4/c1-19-15-9-10(6-7-13(15)17)8-12-11-4-2-3-5-14(11)20-16(12)18/h2-9,17H,1H3/b12-8+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 6.30E+5n/an/an/an/an/an/a



Kumamoto University

Curated by ChEMBL


Assay Description
Inhibitory concentration against DNA topoisomerase I activity

Bioorg Med Chem Lett 15: 2065-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.052
BindingDB Entry DOI: 10.7270/Q2WH2R6D
More data for this
Ligand-Target Pair
DNA topoisomerase 1


(Homo sapiens (Human))		BDBM50410160
PNG
(CHEMBL381195)
Show SMILES COc1ccc(\C=C2\C(=O)Oc3ccccc23)cc1O
Show InChI InChI=1S/C16H12O4/c1-19-15-7-6-10(9-13(15)17)8-12-11-4-2-3-5-14(11)20-16(12)18/h2-9,17H,1H3/b12-8+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 8.00E+5n/an/an/an/an/an/a



Kumamoto University

Curated by ChEMBL


Assay Description
Inhibitory concentration against DNA topoisomerase I activity

Bioorg Med Chem Lett 15: 2065-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.052
BindingDB Entry DOI: 10.7270/Q2WH2R6D
More data for this
Ligand-Target Pair
DNA topoisomerase 1


(Homo sapiens (Human))		BDBM50410151
PNG
(CHEMBL381410)
Show SMILES Oc1ccc2OC(=O)\C(=C\c3ccccc3)c2c1
Show InChI InChI=1S/C15H10O3/c16-11-6-7-14-12(9-11)13(15(17)18-14)8-10-4-2-1-3-5-10/h1-9,16H/b13-8+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 9.60E+5n/an/an/an/an/an/a



Kumamoto University

Curated by ChEMBL


Assay Description
Inhibitory concentration against DNA topoisomerase I activity

Bioorg Med Chem Lett 15: 2065-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.052
BindingDB Entry DOI: 10.7270/Q2WH2R6D
More data for this
Ligand-Target Pair
DNA topoisomerase 1


(Homo sapiens (Human))		BDBM50410162
PNG
(CHEMBL193628)
Show SMILES CCOC(=O)Cc1ccc(\C=C2\C(=O)Oc3ccccc23)cc1
Show InChI InChI=1S/C19H16O4/c1-2-22-18(20)12-14-9-7-13(8-10-14)11-16-15-5-3-4-6-17(15)23-19(16)21/h3-11H,2,12H2,1H3/b16-11+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+6n/an/an/an/an/an/a



Kumamoto University

Curated by ChEMBL


Assay Description
Inhibitory concentration against DNA topoisomerase I activity

Bioorg Med Chem Lett 15: 2065-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.052
BindingDB Entry DOI: 10.7270/Q2WH2R6D
More data for this
Ligand-Target Pair
DNA topoisomerase 1


(Homo sapiens (Human))		BDBM50410161
PNG
(CHEMBL191804)
Show SMILES O=C1Oc2ccccc2\C1=C/c1ccccc1
Show InChI InChI=1S/C15H10O2/c16-15-13(10-11-6-2-1-3-7-11)12-8-4-5-9-14(12)17-15/h1-10H/b13-10+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+6n/an/an/an/an/an/a



Kumamoto University

Curated by ChEMBL


Assay Description
Inhibitory concentration against DNA topoisomerase I activity

Bioorg Med Chem Lett 15: 2065-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.052
BindingDB Entry DOI: 10.7270/Q2WH2R6D
More data for this
Ligand-Target Pair
DNA topoisomerase 1


(Homo sapiens (Human))		BDBM50410157
PNG
(CHEMBL191658)
Show SMILES COc1ccc(\C=C2\C(=O)Oc3ccccc23)cc1
Show InChI InChI=1S/C16H12O3/c1-18-12-8-6-11(7-9-12)10-14-13-4-2-3-5-15(13)19-16(14)17/h2-10H,1H3/b14-10+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+6n/an/an/an/an/an/a



Kumamoto University

Curated by ChEMBL


Assay Description
Inhibitory concentration against DNA topoisomerase I activity

Bioorg Med Chem Lett 15: 2065-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.052
BindingDB Entry DOI: 10.7270/Q2WH2R6D
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%