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PubMed code 16112861

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50172067
PNG
(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)
Show SMILES CS(=O)(=O)N1CCCc2cccc(N3CCN(CC3)C(=O)C(Cc3ccc(Cl)cc3)NC(=O)[C@H]3Cc4ccccc4CN3)c12
Show InChI InChI=1S/C33H38ClN5O4S/c1-44(42,43)39-15-5-9-24-8-4-10-30(31(24)39)37-16-18-38(19-17-37)33(41)29(20-23-11-13-27(34)14-12-23)36-32(40)28-21-25-6-2-3-7-26(25)22-35-28/h2-4,6-8,10-14,28-29,35H,5,9,15-22H2,1H3,(H,36,40)/t28-,29?/m1/s1
PDB

KEGG

UniProtKB/SwissProt

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GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
900n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [125I]-NDP MSH binding towards human melanocortin 4 receptor


Bioorg Med Chem Lett 15: 4459-62 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.035
BindingDB Entry DOI: 10.7270/Q2NV9HTH
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50172074
PNG
(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)
Show SMILES CS(=O)(=O)N1CCc2cccc(N3CCN(CC3)C(=O)C(Cc3ccc(Cl)cc3)NC(=O)[C@H]3Cc4ccccc4CN3)c12
Show InChI InChI=1S/C32H36ClN5O4S/c1-43(41,42)38-14-13-23-7-4-8-29(30(23)38)36-15-17-37(18-16-36)32(40)28(19-22-9-11-26(33)12-10-22)35-31(39)27-20-24-5-2-3-6-25(24)21-34-27/h2-12,27-28,34H,13-21H2,1H3,(H,35,39)/t27-,28?/m1/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
900n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [125I]-NDP MSH binding towards human melanocortin 4 receptor


Bioorg Med Chem Lett 15: 4459-62 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.035
BindingDB Entry DOI: 10.7270/Q2NV9HTH
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%