Affinity Data by PubMed id=16250656

PubMed code 16250656

Found 4 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glucagon receptor (Homo sapiens (Human))	BDBM50075780 (4-[5-(4-Chloro-phenyl)-3-isopropyl-1H-pyrrol-2-yl]...) Show SMILES CC(C)c1cc([nH]c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacopeia Inc. Curated by ChEMBL					Assay Description Antagonist activity against glucagon receptor				J Med Chem 48: 6980-90 (2005) Article DOI: 10.1021/jm050563r BindingDB Entry DOI: 10.7270/Q2RV0N72
Pharmacopeia Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50075782 (4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-1H-pyrrol-2-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacopeia Inc. Curated by ChEMBL					Assay Description Inhibitiory activity against Mitogen-activated protein kinase 14, p38-alpha				J Med Chem 48: 6980-90 (2005) Article DOI: 10.1021/jm050563r BindingDB Entry DOI: 10.7270/Q2RV0N72
Pharmacopeia Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50071899 (4-[5-(4-Chloro-phenyl)-3-(4-fluoro-phenyl)-1H-pyrr...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacopeia Inc. Curated by ChEMBL					Assay Description Antagonist activity against glucagon receptor				J Med Chem 48: 6980-90 (2005) Article DOI: 10.1021/jm050563r BindingDB Entry DOI: 10.7270/Q2RV0N72
Pharmacopeia Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50071899 (4-[5-(4-Chloro-phenyl)-3-(4-fluoro-phenyl)-1H-pyrr...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacopeia Inc. Curated by ChEMBL					Assay Description Inhibitiory activity against Mitogen-activated protein kinase 14, p38-alpha				J Med Chem 48: 6980-90 (2005) Article DOI: 10.1021/jm050563r BindingDB Entry DOI: 10.7270/Q2RV0N72
Pharmacopeia Inc. Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%