Affinity Data by PubMed id=16643021

PubMed code 16643021

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50259746 ((4-Hydroxyphenyl)ethyl trans-ferulate \| CHEMBL4812...) Show SMILES COc1cc(\C=C\C(=O)OCCc2ccc(O)cc2)ccc1O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.76E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells by liquid scintillation counting				J Nat Prod 69: 536-41 (2006) Article DOI: 10.1021/np050301s BindingDB Entry DOI: 10.7270/Q2ST7PM1
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50071370 ((3R,8S)-falcarindiol \| (3R,8S,)-heptadeca-1,9-dien...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.18E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells by liquid scintillation counting				J Nat Prod 69: 536-41 (2006) Article DOI: 10.1021/np050301s BindingDB Entry DOI: 10.7270/Q2ST7PM1
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50250299 ((9Z,11S,16R)-dihydroxyoctadeca-9,17-dien-12,14-diy...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.18E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells by liquid scintillation counting				J Nat Prod 69: 536-41 (2006) Article DOI: 10.1021/np050301s BindingDB Entry DOI: 10.7270/Q2ST7PM1
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50241315 ((Z)-3-butylideneisobenzofuran-1(3H)-one \| CHEMBL24...) Show SMILES CCC\C=C1/OC(=O)c2ccccc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.27E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells by liquid scintillation counting				J Nat Prod 69: 536-41 (2006) Article DOI: 10.1021/np050301s BindingDB Entry DOI: 10.7270/Q2ST7PM1
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50259759 ((S)-8-hydroxy-1-methoxy-, Z-9-heptadecene-4,6-diyn...) Show SMILES CCCCCCC\C=C/[C@H](O)C#CC#CC(=O)CCOC \|r\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells by liquid scintillation counting				J Nat Prod 69: 536-41 (2006) Article DOI: 10.1021/np050301s BindingDB Entry DOI: 10.7270/Q2ST7PM1
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%