Found 55 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Motilin receptor
(Homo sapiens (Human)) | BDBM50002694
(MOTILIN)Show SMILES [#6]-[#6]-[#6@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-c1ccccc1)-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6@@H](-[#6])-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@H](-[#6]-[#6]-[#16]-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6](-[#7])=O)-[#6](-[#8])=O |r| Show InChI InChI=1S/C120H188N34O35S/c1-9-64(6)97(152-114(184)86-31-22-53-154(86)117(187)96(63(4)5)151-99(169)70(123)56-66-23-12-10-13-24-66)115(185)150-84(57-67-25-14-11-15-26-67)113(183)153-98(65(7)155)116(186)149-83(58-68-32-34-69(156)35-33-68)101(171)135-60-91(161)136-75(39-45-93(163)164)105(175)147-82(55-62(2)3)111(181)145-77(37-43-88(125)158)106(176)140-73(29-20-51-132-119(128)129)103(173)146-80(48-54-190-8)110(180)142-76(36-42-87(124)157)107(177)144-79(41-47-95(167)168)108(178)139-72(28-17-19-50-122)102(172)143-78(40-46-94(165)166)109(179)141-74(30-21-52-133-120(130)131)104(174)148-85(59-90(127)160)112(182)138-71(27-16-18-49-121)100(170)134-61-92(162)137-81(118(188)189)38-44-89(126)159/h10-15,23-26,32-35,62-65,70-86,96-98,155-156H,9,16-22,27-31,36-61,121-123H2,1-8H3,(H2,124,157)(H2,125,158)(H2,126,159)(H2,127,160)(H,134,170)(H,135,171)(H,136,161)(H,137,162)(H,138,182)(H,139,178)(H,140,176)(H,141,179)(H,142,180)(H,143,172)(H,144,177)(H,145,181)(H,146,173)(H,147,175)(H,148,174)(H,149,186)(H,150,185)(H,151,169)(H,152,184)(H,153,183)(H,163,164)(H,165,166)(H,167,168)(H,188,189)(H4,128,129,132)(H4,130,131,133)/t64-,65+,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80+,81-,82-,83-,84-,85-,86-,96-,97-,98-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 0.360 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199368
((9R,12R,15S)-12-isopropyl-9-(4-methoxy-benzyl)-15-...)Show SMILES CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](Cc2ccc(OC)cc2)NCCOc2ccccc2CCCNC1=O)C(C)C Show InChI InChI=1S/C31H44N4O5/c1-5-9-25-29(36)33-17-8-11-23-10-6-7-12-27(23)40-19-18-32-26(20-22-13-15-24(39-4)16-14-22)30(37)35-28(21(2)3)31(38)34-25/h6-7,10,12-16,21,25-26,28,32H,5,8-9,11,17-20H2,1-4H3,(H,33,36)(H,34,38)(H,35,37)/t25-,26+,28+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199372
((9R,12R,15S)-12-isopropyl-9-naphthalen-1-ylmethyl-...)Show SMILES CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](Cc2cccc3ccccc23)NCCOc2ccccc2CCCNC1=O)C(C)C Show InChI InChI=1S/C34H44N4O4/c1-4-11-28-32(39)36-19-10-16-25-13-6-8-18-30(25)42-21-20-35-29(33(40)38-31(23(2)3)34(41)37-28)22-26-15-9-14-24-12-5-7-17-27(24)26/h5-9,12-15,17-18,23,28-29,31,35H,4,10-11,16,19-22H2,1-3H3,(H,36,39)(H,37,41)(H,38,40)/t28-,29+,31+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 8.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199359
((9R,12R,15S)-9-benzo[b]thiophen-3-ylmethyl-12-isop...)Show SMILES CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](Cc2csc3ccccc23)NCCOc2ccccc2CCCNC1=O)C(C)C Show InChI InChI=1S/C32H42N4O4S/c1-4-10-25-30(37)34-16-9-12-22-11-5-7-14-27(22)40-18-17-33-26(31(38)36-29(21(2)3)32(39)35-25)19-23-20-41-28-15-8-6-13-24(23)28/h5-8,11,13-15,20-21,25-26,29,33H,4,9-10,12,16-19H2,1-3H3,(H,34,37)(H,35,39)(H,36,38)/t25-,26+,29+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199397
((9R,12R,15S)-9-(4-hydroxy-benzyl)-12-isopropyl-15-...)Show SMILES CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](Cc2ccc(O)cc2)NCCOc2ccccc2CCCNC1=O)C(C)C Show InChI InChI=1S/C30H42N4O5/c1-4-8-24-28(36)32-16-7-10-22-9-5-6-11-26(22)39-18-17-31-25(19-21-12-14-23(35)15-13-21)29(37)34-27(20(2)3)30(38)33-24/h5-6,9,11-15,20,24-25,27,31,35H,4,7-8,10,16-19H2,1-3H3,(H,32,36)(H,33,38)(H,34,37)/t24-,25+,27+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 55 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199347
((9R,12R,15S)-9-benzyl-12-isopropyl-15-propyl-6,7,8...)Show SMILES CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](Cc2ccccc2)NCCOc2ccccc2CCCNC1=O)C(C)C Show InChI InChI=1S/C30H42N4O4/c1-4-11-24-28(35)32-17-10-15-23-14-8-9-16-26(23)38-19-18-31-25(20-22-12-6-5-7-13-22)29(36)34-27(21(2)3)30(37)33-24/h5-9,12-14,16,21,24-25,27,31H,4,10-11,15,17-20H2,1-3H3,(H,32,35)(H,33,37)(H,34,36)/t24-,25+,27+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 57 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199353
((9R,12R,15S)-9-(4-hydroxy-benzyl)-15-isobutyl-12-i...)Show SMILES CC(C)C[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](Cc2ccc(O)cc2)NCCOc2ccccc2\C=C\CNC1=O)C(C)C |t:33| Show InChI InChI=1S/C31H42N4O5/c1-20(2)18-26-29(37)33-15-7-9-23-8-5-6-10-27(23)40-17-16-32-25(19-22-11-13-24(36)14-12-22)30(38)35-28(21(3)4)31(39)34-26/h5-14,20-21,25-26,28,32,36H,15-19H2,1-4H3,(H,33,37)(H,34,39)(H,35,38)/b9-7+/t25-,26+,28-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 62 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199373
((9R,12R,15S)-9-benzyl-12-isopropyl-15-propyl-6,7,8...)Show SMILES CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](Cc2ccccc2)NCCOc2ccccc2\C=C\CNC1=O)C(C)C |t:31| Show InChI InChI=1S/C30H40N4O4/c1-4-11-24-28(35)32-17-10-15-23-14-8-9-16-26(23)38-19-18-31-25(20-22-12-6-5-7-13-22)29(36)34-27(21(2)3)30(37)33-24/h5-10,12-16,21,24-25,27,31H,4,11,17-20H2,1-3H3,(H,32,35)(H,33,37)(H,34,36)/b15-10+/t24-,25+,27+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 78 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199396
((9R,12R,15S)-12-isopropyl-9-naphthalen-2-ylmethyl-...)Show SMILES CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](Cc2ccc3ccccc3c2)NCCOc2ccccc2CCCNC1=O)C(C)C Show InChI InChI=1S/C34H44N4O4/c1-4-10-28-32(39)36-18-9-14-26-12-7-8-15-30(26)42-20-19-35-29(33(40)38-31(23(2)3)34(41)37-28)22-24-16-17-25-11-5-6-13-27(25)21-24/h5-8,11-13,15-17,21,23,28-29,31,35H,4,9-10,14,18-20,22H2,1-3H3,(H,36,39)(H,37,41)(H,38,40)/t28-,29+,31+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 79 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199365
((E)-(9R,12R,15S)-9-(4-hydroxy-benzyl)-12-isopropyl...)Show SMILES CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](Cc2ccc(O)cc2)NCCOc2ccccc2\C=C\CNC1=O)C(C)C |t:32| Show InChI InChI=1S/C30H40N4O5/c1-4-8-24-28(36)32-16-7-10-22-9-5-6-11-26(22)39-18-17-31-25(19-21-12-14-23(35)15-13-21)29(37)34-27(20(2)3)30(38)33-24/h5-7,9-15,20,24-25,27,31,35H,4,8,16-19H2,1-3H3,(H,32,36)(H,33,38)(H,34,37)/b10-7+/t24-,25+,27+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 137 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199362
((9R,12R,15S)-15-benzyl-9-(4-hydroxy-benzyl)-12-iso...)Show SMILES CC(C)[C@H]1NC(=O)[C@@H](Cc2ccc(O)cc2)NCCOc2ccccc2\C=C\CNC(=O)[C@H](Cc2ccccc2)NC1=O |t:28| Show InChI InChI=1S/C34H40N4O5/c1-23(2)31-34(42)37-29(22-24-9-4-3-5-10-24)32(40)36-18-8-12-26-11-6-7-13-30(26)43-20-19-35-28(33(41)38-31)21-25-14-16-27(39)17-15-25/h3-17,23,28-29,31,35,39H,18-22H2,1-2H3,(H,36,40)(H,37,42)(H,38,41)/b12-8+/t28-,29+,31-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 185 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199394
((9R,12R,15S)-9-(4-hydroxy-benzyl)-12-isopropyl-15-...)Show SMILES CCC[C@@H]1NC(=O)[C@H](OC(=O)[C@@H](Cc2ccc(O)cc2)NCCOc2ccccc2CCCNC1=O)C(C)C Show InChI InChI=1S/C30H41N3O6/c1-4-8-24-28(35)32-16-7-10-22-9-5-6-11-26(22)38-18-17-31-25(19-21-12-14-23(34)15-13-21)30(37)39-27(20(2)3)29(36)33-24/h5-6,9,11-15,20,24-25,27,31,34H,4,7-8,10,16-19H2,1-3H3,(H,32,35)(H,33,36)/t24-,25+,27+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 192 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199364
((9R,12R,15S)-9-(4-hydroxy-benzyl)-12-methyl-15-pro...)Show SMILES CCC[C@@H]1NC(=O)[C@@H](C)NC(=O)[C@@H](Cc2ccc(O)cc2)NCCOc2ccccc2\C=C\CNC1=O |t:33| Show InChI InChI=1S/C28H36N4O5/c1-3-7-23-27(35)30-15-6-9-21-8-4-5-10-25(21)37-17-16-29-24(18-20-11-13-22(33)14-12-20)28(36)31-19(2)26(34)32-23/h4-6,8-14,19,23-24,29,33H,3,7,15-18H2,1-2H3,(H,30,35)(H,31,36)(H,32,34)/b9-6+/t19-,23+,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 196 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199392
((9R,12R,15S)-9-(4-hydroxy-benzyl)-15-isobutyl-12-i...)Show SMILES CC(C)C[C@@H]1N(C)C(=O)[C@H](NC(=O)[C@@H](Cc2ccc(O)cc2)NCCOc2ccccc2CCCNC1=O)C(C)C Show InChI InChI=1S/C32H46N4O5/c1-21(2)19-27-31(39)34-16-8-10-24-9-6-7-11-28(24)41-18-17-33-26(20-23-12-14-25(37)15-13-23)30(38)35-29(22(3)4)32(40)36(27)5/h6-7,9,11-15,21-22,26-27,29,33,37H,8,10,16-20H2,1-5H3,(H,34,39)(H,35,38)/t26-,27+,29-/m1/s1 | PDB
Reactome pathway
KEGG
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DrugBank
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PC sid
UniChem
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| Article
PubMed
| 222 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199346
((9R,12R,15S)-9-(1H-indol-3-ylmethyl)-12-isopropyl-...)Show SMILES CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NCCOc2ccccc2CCCNC1=O)C(C)C Show InChI InChI=1S/C32H43N5O4/c1-4-10-26-30(38)34-16-9-12-22-11-5-8-15-28(22)41-18-17-33-27(31(39)37-29(21(2)3)32(40)36-26)19-23-20-35-25-14-7-6-13-24(23)25/h5-8,11,13-15,20-21,26-27,29,33,35H,4,9-10,12,16-19H2,1-3H3,(H,34,38)(H,36,40)(H,37,39)/t26-,27+,29+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 255 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199390
((9R,12R,15R)-9-(4-Hydroxy-benzyl)-12-isopropyl-15-...)Show SMILES CCC[C@H]1NC(=O)[C@H](NC(=O)[C@@H](Cc2ccc(O)cc2)NCCOc2ccccc2\C=C\CNC1=O)C(C)C |t:32| Show InChI InChI=1S/C30H40N4O5/c1-4-8-24-28(36)32-16-7-10-22-9-5-6-11-26(22)39-18-17-31-25(19-21-12-14-23(35)15-13-21)29(37)34-27(20(2)3)30(38)33-24/h5-7,9-15,20,24-25,27,31,35H,4,8,16-19H2,1-3H3,(H,32,36)(H,33,38)(H,34,37)/b10-7+/t24-,25-,27-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 335 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199376
((9R,12R,15S)-9-(4-hydroxy-benzyl)-15-hydroxymethyl...)Show SMILES CC(C)[C@H]1NC(=O)[C@@H](Cc2ccc(O)cc2)NCCOc2ccccc2\C=C\CNC(=O)[C@H](CO)NC1=O |t:28| Show InChI InChI=1S/C28H36N4O6/c1-18(2)25-28(37)31-23(17-33)26(35)30-13-5-7-20-6-3-4-8-24(20)38-15-14-29-22(27(36)32-25)16-19-9-11-21(34)12-10-19/h3-12,18,22-23,25,29,33-34H,13-17H2,1-2H3,(H,30,35)(H,31,37)(H,32,36)/b7-5+/t22-,23+,25-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 650 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199378
((9R,12R,15S)-15-(4-amino-butyl)-9-(4-hydroxy-benzy...)Show SMILES CC(C)[C@H]1NC(=O)[C@@H](Cc2ccc(O)cc2)NCCOc2ccccc2\C=C\CNC(=O)[C@H](CCCCN)NC1=O |t:28| Show InChI InChI=1S/C31H43N5O5/c1-21(2)28-31(40)35-25(10-5-6-16-32)29(38)34-17-7-9-23-8-3-4-11-27(23)41-19-18-33-26(30(39)36-28)20-22-12-14-24(37)15-13-22/h3-4,7-9,11-15,21,25-26,28,33,37H,5-6,10,16-20,32H2,1-2H3,(H,34,38)(H,35,40)(H,36,39)/b9-7+/t25-,26+,28+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 664 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199349
((E)-(3S,6R,9R)-9-(4-hydroxy-benzyl)-6-isopropyl-3-...)Show SMILES CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](Cc2ccc(O)cc2)NC\C=C\CCNC1=O)C(C)C |t:23| Show InChI InChI=1S/C24H36N4O4/c1-4-8-19-22(30)26-14-7-5-6-13-25-20(15-17-9-11-18(29)12-10-17)23(31)28-21(16(2)3)24(32)27-19/h5-6,9-12,16,19-21,25,29H,4,7-8,13-15H2,1-3H3,(H,26,30)(H,27,32)(H,28,31)/b6-5+/t19-,20+,21+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 701 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199361
((9R,12R,15S)-9-(4-hydroxy-benzyl)-12-isopropyl-15-...)Show SMILES CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](Cc2ccc(O)cc2)NCCOc2ccccc2CCNC1=O)C(C)C Show InChI InChI=1S/C29H40N4O5/c1-4-7-23-27(35)31-15-14-21-8-5-6-9-25(21)38-17-16-30-24(18-20-10-12-22(34)13-11-20)28(36)33-26(19(2)3)29(37)32-23/h5-6,8-13,19,23-24,26,30,34H,4,7,14-18H2,1-3H3,(H,31,35)(H,32,37)(H,33,36)/t23-,24+,26+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 982 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199360
((3S,6R,9R)-9-(4-hydroxy-benzyl)-6-isopropyl-3-prop...)Show SMILES CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](Cc2ccc(O)cc2)NCCCCCCCCNC1=O)C(C)C Show InChI InChI=1S/C27H44N4O4/c1-4-11-22-25(33)29-17-10-8-6-5-7-9-16-28-23(18-20-12-14-21(32)15-13-20)26(34)31-24(19(2)3)27(35)30-22/h12-15,19,22-24,28,32H,4-11,16-18H2,1-3H3,(H,29,33)(H,30,35)(H,31,34)/t22-,23+,24+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199351
((9R,12R,15S)-9-(4-hydroxy-benzyl)-12-isopropyl-15-...)Show SMILES CC(C)[C@H]1NC(=O)[C@@H](Cc2ccc(O)cc2)NCCOc2ccccc2\C=C\CNC(=O)[C@H](C)NC1=O |t:28| Show InChI InChI=1S/C28H36N4O5/c1-18(2)25-28(36)31-19(3)26(34)30-14-6-8-21-7-4-5-9-24(21)37-16-15-29-23(27(35)32-25)17-20-10-12-22(33)13-11-20/h4-13,18-19,23,25,29,33H,14-17H2,1-3H3,(H,30,34)(H,31,36)(H,32,35)/b8-6+/t19-,23+,25+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.39E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199363
((9R,12R,15S)-12-isopropyl-9-phenethyl-15-propyl-6,...)Show SMILES CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](CCc2ccccc2)NCCOc2ccccc2CCCNC1=O)C(C)C Show InChI InChI=1S/C31H44N4O4/c1-4-11-26-29(36)33-19-10-15-24-14-8-9-16-27(24)39-21-20-32-25(18-17-23-12-6-5-7-13-23)30(37)35-28(22(2)3)31(38)34-26/h5-9,12-14,16,22,25-26,28,32H,4,10-11,15,17-21H2,1-3H3,(H,33,36)(H,34,38)(H,35,37)/t25-,26+,28-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.49E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199377
((9R,12R,15S)-12-benzyl-9-(4-hydroxy-benzyl)-15-pro...)Show SMILES CCC[C@@H]1NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccc(O)cc2)NCCOc2ccccc2\C=C\CNC1=O |t:40| Show InChI InChI=1S/C34H40N4O5/c1-2-9-28-32(40)36-19-8-13-26-12-6-7-14-31(26)43-21-20-35-29(22-25-15-17-27(39)18-16-25)33(41)38-30(34(42)37-28)23-24-10-4-3-5-11-24/h3-8,10-18,28-30,35,39H,2,9,19-23H2,1H3,(H,36,40)(H,37,42)(H,38,41)/b13-8+/t28-,29+,30+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.52E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199389
((9R,12R,15S)-9-(4-hydroxy-benzyl)-12-isopropyl-15-...)Show SMILES CCC[C@@H]1OC(=O)[C@H](NC(=O)[C@@H](Cc2ccc(O)cc2)NCCOc2ccccc2CCCNC1=O)C(C)C Show InChI InChI=1S/C30H41N3O6/c1-4-8-26-29(36)32-16-7-10-22-9-5-6-11-25(22)38-18-17-31-24(19-21-12-14-23(34)15-13-21)28(35)33-27(20(2)3)30(37)39-26/h5-6,9,11-15,20,24,26-27,31,34H,4,7-8,10,16-19H2,1-3H3,(H,32,36)(H,33,35)/t24-,26+,27-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.88E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199352
((9R,13R,16S)-9-(4-hydroxy-benzyl)-13-isopropyl-16-...)Show SMILES CCC[C@@H]1NC(=O)[C@H](NNC(=O)[C@@H](Cc2ccc(O)cc2)NCCOc2ccccc2CCCNC1=O)C(C)C Show InChI InChI=1S/C30H43N5O5/c1-4-8-24-28(37)32-16-7-10-22-9-5-6-11-26(22)40-18-17-31-25(19-21-12-14-23(36)15-13-21)29(38)35-34-27(20(2)3)30(39)33-24/h5-6,9,11-15,20,24-25,27,31,34,36H,4,7-8,10,16-19H2,1-3H3,(H,32,37)(H,33,39)(H,35,38)/t24-,25+,27+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.37E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199382
((9R,12R,15S)-9-(4-hydroxy-benzyl)-12-isopropyl-10,...)Show SMILES CC(C)[C@H]1NC(=O)[C@@H](Cc2ccc(O)cc2)NCCOc2ccccc2\C=C\CNC(=O)[C@H](CC(O)=O)NC1=O |t:28| Show InChI InChI=1S/C29H36N4O7/c1-18(2)26-29(39)32-23(17-25(35)36)27(37)31-13-5-7-20-6-3-4-8-24(20)40-15-14-30-22(28(38)33-26)16-19-9-11-21(34)12-10-19/h3-12,18,22-23,26,30,34H,13-17H2,1-2H3,(H,31,37)(H,32,39)(H,33,38)(H,35,36)/b7-5+/t22-,23+,26-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.55E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199391
((9R,12R,15S)-9-(4-hydroxy-benzyl)-12-isopropyl-8-m...)Show SMILES CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](Cc2ccc(O)cc2)N(C)CCOc2ccccc2CCCNC1=O)C(C)C Show InChI InChI=1S/C31H44N4O5/c1-5-9-25-29(37)32-17-8-11-23-10-6-7-12-27(23)40-19-18-35(4)26(20-22-13-15-24(36)16-14-22)30(38)34-28(21(2)3)31(39)33-25/h6-7,10,12-16,21,25-26,28,36H,5,8-9,11,17-20H2,1-4H3,(H,32,37)(H,33,39)(H,34,38)/t25-,26+,28+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.78E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199385
((9R,12R,15S)-9-(4-hydroxy-benzyl)-12-isopropyl-15-...)Show SMILES CCC[C@@H]1NC(=O)[C@H](NC[C@@H](Cc2ccc(O)cc2)NCCOc2ccccc2CCCNC1=O)C(C)C Show InChI InChI=1S/C30H44N4O4/c1-4-8-26-29(36)32-16-7-10-23-9-5-6-11-27(23)38-18-17-31-24(19-22-12-14-25(35)15-13-22)20-33-28(21(2)3)30(37)34-26/h5-6,9,11-15,21,24,26,28,31,33,35H,4,7-8,10,16-20H2,1-3H3,(H,32,36)(H,34,37)/t24-,26+,28-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199350
((9R,12R,15S)-9-cyclohexylmethyl-12-isopropyl-15-pr...)Show SMILES CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](CC2CCCCC2)NCCOc2ccccc2CCCNC1=O)C(C)C Show InChI InChI=1S/C30H48N4O4/c1-4-11-24-28(35)32-17-10-15-23-14-8-9-16-26(23)38-19-18-31-25(20-22-12-6-5-7-13-22)29(36)34-27(21(2)3)30(37)33-24/h8-9,14,16,21-22,24-25,27,31H,4-7,10-13,15,17-20H2,1-3H3,(H,32,35)(H,33,37)(H,34,36)/t24-,25+,27+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199388
((9R,12R,15S)-9,12-diisopropyl-15-propyl-6,7,8,9,11...)Show SMILES CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@H](NCCOc2ccccc2\C=C\CNC1=O)C(C)C)C(C)C |t:23| Show InChI InChI=1S/C26H40N4O4/c1-6-10-20-24(31)28-14-9-12-19-11-7-8-13-21(19)34-16-15-27-22(17(2)3)25(32)30-23(18(4)5)26(33)29-20/h7-9,11-13,17-18,20,22-23,27H,6,10,14-16H2,1-5H3,(H,28,31)(H,29,33)(H,30,32)/b12-9+/t20-,22+,23+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.57E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199383
(3-[(9R,12R,15S)-9-(4-hydroxy-benzyl)-10,13,16-trio...)Show SMILES CCC[C@@H]1NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](Cc2ccc(O)cc2)NCCOc2ccccc2\C=C\CNC1=O |t:37| Show InChI InChI=1S/C30H38N4O7/c1-2-6-23-28(38)32-16-5-8-21-7-3-4-9-26(21)41-18-17-31-25(19-20-10-12-22(35)13-11-20)30(40)34-24(29(39)33-23)14-15-27(36)37/h3-5,7-13,23-25,31,35H,2,6,14-19H2,1H3,(H,32,38)(H,33,39)(H,34,40)(H,36,37)/b8-5+/t23-,24+,25+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199357
((9S,12R,15R)-15-(4-hydroxy-benzyl)-12-isopropyl-9-...)Show SMILES CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](Cc2ccc(O)cc2)NCCCCc2ccccc2CCNC1=O)C(C)C Show InChI InChI=1S/C31H44N4O4/c1-4-9-26-29(37)33-19-17-24-11-6-5-10-23(24)12-7-8-18-32-27(20-22-13-15-25(36)16-14-22)30(38)35-28(21(2)3)31(39)34-26/h5-6,10-11,13-16,21,26-28,32,36H,4,7-9,12,17-20H2,1-3H3,(H,33,37)(H,34,39)(H,35,38)/t26-,27+,28+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199358
((8R,11R,14S)-8-(4-hydroxy-benzyl)-11-isopropyl-14-...)Show SMILES CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](Cc2ccc(O)cc2)NCCc2ccccc2CCCCNC1=O)C(C)C Show InChI InChI=1S/C31H44N4O4/c1-4-9-26-29(37)33-18-8-7-12-23-10-5-6-11-24(23)17-19-32-27(20-22-13-15-25(36)16-14-22)30(38)35-28(21(2)3)31(39)34-26/h5-6,10-11,13-16,21,26-28,32,36H,4,7-9,12,17-20H2,1-3H3,(H,33,37)(H,34,39)(H,35,38)/t26-,27+,28+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199366
((9R,12R,15S)-8-acetyl-9-(4-hydroxy-benzyl)-12-isop...)Show SMILES CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](Cc2ccc(O)cc2)N(CCOc2ccccc2CCCNC1=O)C(C)=O)C(C)C Show InChI InChI=1S/C32H44N4O6/c1-5-9-26-30(39)33-17-8-11-24-10-6-7-12-28(24)42-19-18-36(22(4)37)27(20-23-13-15-25(38)16-14-23)31(40)35-29(21(2)3)32(41)34-26/h6-7,10,12-16,21,26-27,29,38H,5,8-9,11,17-20H2,1-4H3,(H,33,39)(H,34,41)(H,35,40)/t26-,27+,29+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6.39E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199374
((E/Z)-(9R,12R,15S)-9-(4-hydroxy-benzyl)-12-isoprop...)Show SMILES CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](Cc2ccc(O)cc2)NCCCc2ccccc2\C=C/CCNC1=O)C(C)C |c:32| Show InChI InChI=1S/C32H44N4O4/c1-4-10-27-30(38)34-19-8-7-13-24-11-5-6-12-25(24)14-9-20-33-28(21-23-15-17-26(37)18-16-23)31(39)36-29(22(2)3)32(40)35-27/h5-7,11-13,15-18,22,27-29,33,37H,4,8-10,14,19-21H2,1-3H3,(H,34,38)(H,35,40)(H,36,39)/b13-7-/t27-,28+,29+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199393
((E/Z)-(8R,11R,14S)-8-(4-Hydroxy-benzyl)-11-isoprop...)Show SMILES CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](Cc2ccc(O)cc2)NCCc2ccccc2\C=C\CNC1=O)C(C)C |t:31| Show InChI InChI=1S/C30H40N4O4/c1-4-8-25-28(36)32-17-7-11-22-9-5-6-10-23(22)16-18-31-26(19-21-12-14-24(35)15-13-21)29(37)34-27(20(2)3)30(38)33-25/h5-7,9-15,20,25-27,31,35H,4,8,16-19H2,1-3H3,(H,32,36)(H,33,38)(H,34,37)/b11-7+/t25-,26+,27+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 9.73E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199370
((7R,10R,13S)-7-(4-hydroxy-benzyl)-10-isopropyl-13-...)Show SMILES CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](Cc2ccc(O)cc2)NCc2ccccc2CCCCNC1=O)C(C)C Show InChI InChI=1S/C30H42N4O4/c1-4-9-25-28(36)31-17-8-7-11-22-10-5-6-12-23(22)19-32-26(18-21-13-15-24(35)16-14-21)29(37)34-27(20(2)3)30(38)33-25/h5-6,10,12-16,20,25-27,32,35H,4,7-9,11,17-19H2,1-3H3,(H,31,36)(H,33,38)(H,34,37)/t25-,26+,27+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199386
((9R,12R,15S)-9-(4-amino-butyl)-12-isopropyl-15-pro...)Show SMILES CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](CCCCN)NCCOc2ccccc2\C=C\CNC1=O)C(C)C |t:28| Show InChI InChI=1S/C27H43N5O4/c1-4-10-22-25(33)30-16-9-12-20-11-5-6-14-23(20)36-18-17-29-21(13-7-8-15-28)26(34)32-24(19(2)3)27(35)31-22/h5-6,9,11-12,14,19,21-22,24,29H,4,7-8,10,13,15-18,28H2,1-3H3,(H,30,33)(H,31,35)(H,32,34)/b12-9+/t21-,22+,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199355
(3-((9R,12R,15S)-12-isopropyl-10,13,16-trioxo-15-pr...)Show SMILES CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](CCC(O)=O)NCCOc2ccccc2\C=C\CNC1=O)C(C)C |t:28| Show InChI InChI=1S/C26H38N4O6/c1-4-8-20-24(33)28-14-7-10-18-9-5-6-11-21(18)36-16-15-27-19(12-13-22(31)32)25(34)30-23(17(2)3)26(35)29-20/h5-7,9-11,17,19-20,23,27H,4,8,12-16H2,1-3H3,(H,28,33)(H,29,35)(H,30,34)(H,31,32)/b10-7+/t19-,20+,23-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199348
((8R,11R,14S)-8-(4-hydroxy-benzyl)-11-isopropyl-14-...)Show SMILES CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](Cc2ccc(O)cc2)NCCc2ccccc2CCCNC1=O)C(C)C Show InChI InChI=1S/C30H42N4O4/c1-4-8-25-28(36)32-17-7-11-22-9-5-6-10-23(22)16-18-31-26(19-21-12-14-24(35)15-13-21)29(37)34-27(20(2)3)30(38)33-25/h5-6,9-10,12-15,20,25-27,31,35H,4,7-8,11,16-19H2,1-3H3,(H,32,36)(H,33,38)(H,34,37)/t25-,26+,27+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199379
((E/Z)-(8R,11R,14S)-8-(4-hydroxy-benzyl)-11-isoprop...)Show SMILES CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](Cc2ccc(O)cc2)NCCc2ccccc2\C=C/CCNC1=O)C(C)C |c:31| Show InChI InChI=1S/C31H42N4O4/c1-4-9-26-29(37)33-18-8-7-12-23-10-5-6-11-24(23)17-19-32-27(20-22-13-15-25(36)16-14-22)30(38)35-28(21(2)3)31(39)34-26/h5-7,10-16,21,26-28,32,36H,4,8-9,17-20H2,1-3H3,(H,33,37)(H,34,39)(H,35,38)/b12-7-/t26-,27+,28+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199384
((9R,12R,15S)-12-isopropyl-9-methyl-15-propyl-6,7,8...)Show SMILES CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](C)NCCOc2ccccc2\C=C\CNC1=O)C(C)C |t:24| Show InChI InChI=1S/C24H36N4O4/c1-5-9-19-23(30)26-13-8-11-18-10-6-7-12-20(18)32-15-14-25-17(4)22(29)28-21(16(2)3)24(31)27-19/h6-8,10-12,16-17,19,21,25H,5,9,13-15H2,1-4H3,(H,26,30)(H,27,31)(H,28,29)/b11-8+/t17-,19+,21-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199381
((9S,12R,15S)-9-(4-hydroxy-benzyl)-12-isopropyl-15-...)Show SMILES CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NCCOc2ccccc2\C=C\CNC1=O)C(C)C |t:32| Show InChI InChI=1S/C30H40N4O5/c1-4-8-24-28(36)32-16-7-10-22-9-5-6-11-26(22)39-18-17-31-25(19-21-12-14-23(35)15-13-21)29(37)34-27(20(2)3)30(38)33-24/h5-7,9-15,20,24-25,27,31,35H,4,8,16-19H2,1-3H3,(H,32,36)(H,33,38)(H,34,37)/b10-7+/t24-,25-,27+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199371
((E/Z)-(10S,13R,16R)-16-(4-hydroxy-benzyl)-13-isopr...)Show SMILES CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](Cc2ccc(O)cc2)NCCCc2ccccc2\C=C\CNC1=O)C(C)C |t:32| Show InChI InChI=1S/C31H42N4O4/c1-4-9-26-29(37)33-19-8-13-24-11-6-5-10-23(24)12-7-18-32-27(20-22-14-16-25(36)17-15-22)30(38)35-28(21(2)3)31(39)34-26/h5-6,8,10-11,13-17,21,26-28,32,36H,4,7,9,12,18-20H2,1-3H3,(H,33,37)(H,34,39)(H,35,38)/b13-8+/t26-,27+,28+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199354
((9S,12R,15R)-15-(4-hydroxy-benzyl)-12-isopropyl-9-...)Show SMILES CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](Cc2ccc(O)cc2)NCCCc2ccccc2CCNC1=O)C(C)C Show InChI InChI=1S/C30H42N4O4/c1-4-8-25-28(36)32-18-16-23-10-6-5-9-22(23)11-7-17-31-26(19-21-12-14-24(35)15-13-21)29(37)34-27(20(2)3)30(38)33-25/h5-6,9-10,12-15,20,25-27,31,35H,4,7-8,11,16-19H2,1-3H3,(H,32,36)(H,33,38)(H,34,37)/t25-,26+,27+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199367
((9R,12R,15S)-9-(4-hydroxy-benzyl)-12-hydroxymethyl...)Show SMILES CCC[C@@H]1NC(=O)[C@@H](CO)NC(=O)[C@@H](Cc2ccc(O)cc2)NCCOc2ccccc2\C=C\CNC1=O |t:34| Show InChI InChI=1S/C28H36N4O6/c1-2-6-22-26(35)30-14-5-8-20-7-3-4-9-25(20)38-16-15-29-23(17-19-10-12-21(34)13-11-19)27(36)32-24(18-33)28(37)31-22/h3-5,7-13,22-24,29,33-34H,2,6,14-18H2,1H3,(H,30,35)(H,31,37)(H,32,36)/b8-5+/t22-,23+,24+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199395
((S)-2-((R)-2-((R)-2-(2-(2-((E)-3-acetamidoprop-1-e...)Show SMILES CCC[C@H](NC(=O)[C@H](NC(=O)[C@@H](Cc1ccc(O)cc1)NCCOc1ccccc1\C=C\CNC(C)=O)C(C)C)C(N)=O Show InChI InChI=1S/C32H45N5O6/c1-5-9-26(30(33)40)36-32(42)29(21(2)3)37-31(41)27(20-23-13-15-25(39)16-14-23)35-18-19-43-28-12-7-6-10-24(28)11-8-17-34-22(4)38/h6-8,10-16,21,26-27,29,35,39H,5,9,17-20H2,1-4H3,(H2,33,40)(H,34,38)(H,36,42)(H,37,41)/b11-8+/t26-,27+,29+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199375
((10S,13R,16R)-16-(4-hydroxy-benzyl)-13-isopropyl-1...)Show SMILES CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](Cc2ccc(O)cc2)NCCCc2ccccc2CCCNC1=O)C(C)C Show InChI InChI=1S/C31H44N4O4/c1-4-9-26-29(37)33-19-8-13-24-11-6-5-10-23(24)12-7-18-32-27(20-22-14-16-25(36)17-15-22)30(38)35-28(21(2)3)31(39)34-26/h5-6,10-11,14-17,21,26-28,32,36H,4,7-9,12-13,18-20H2,1-3H3,(H,33,37)(H,34,39)(H,35,38)/t26-,27+,28+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199380
((9R,12R,15S)-12-isopropyl-9-phenyl-15-propyl-6,7,8...)Show SMILES CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@H](NCCOc2ccccc2CCCNC1=O)c1ccccc1)C(C)C Show InChI InChI=1S/C29H40N4O4/c1-4-11-23-27(34)31-17-10-15-21-12-8-9-16-24(21)37-19-18-30-26(22-13-6-5-7-14-22)29(36)33-25(20(2)3)28(35)32-23/h5-9,12-14,16,20,23,25-26,30H,4,10-11,15,17-19H2,1-3H3,(H,31,34)(H,32,35)(H,33,36)/t23-,25+,26+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199369
((9R,12S,15S)-9-(4-hydroxy-benzyl)-12-isopropyl-15-...)Show SMILES CCC[C@@H]1NC(=O)[C@@H](NC(=O)[C@@H](Cc2ccc(O)cc2)NCCOc2ccccc2\C=C\CNC1=O)C(C)C |t:32| Show InChI InChI=1S/C30H40N4O5/c1-4-8-24-28(36)32-16-7-10-22-9-5-6-11-26(22)39-18-17-31-25(19-21-12-14-23(35)15-13-21)29(37)34-27(20(2)3)30(38)33-24/h5-7,9-15,20,24-25,27,31,35H,4,8,16-19H2,1-3H3,(H,32,36)(H,33,38)(H,34,37)/b10-7+/t24-,25+,27-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199387
((9R,12R,15S)-9-(4-hydroxy-benzyl)-12-isopropyl-11-...)Show SMILES CCC[C@@H]1NC(=O)[C@@H](C(C)C)N(C)C(=O)[C@@H](Cc2ccc(O)cc2)NCCOc2ccccc2CCCNC1=O Show InChI InChI=1S/C31H44N4O5/c1-5-9-25-29(37)33-17-8-11-23-10-6-7-12-27(23)40-19-18-32-26(20-22-13-15-24(36)16-14-22)31(39)35(4)28(21(2)3)30(38)34-25/h6-7,10,12-16,21,25-26,28,32,36H,5,8-9,11,17-20H2,1-4H3,(H,33,37)(H,34,38)/t25-,26+,28+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199356
((S)-2-((R)-2-((R)-2-amino-3-(4-hydroxyphenyl)propa...)Show SMILES CCC[C@H](NC(=O)[C@H](NC(=O)[C@H](N)Cc1ccc(O)cc1)C(C)C)C(N)=O Show InChI InChI=1S/C19H30N4O4/c1-4-5-15(17(21)25)22-19(27)16(11(2)3)23-18(26)14(20)10-12-6-8-13(24)9-7-12/h6-9,11,14-16,24H,4-5,10,20H2,1-3H3,(H2,21,25)(H,22,27)(H,23,26)/t14-,15+,16-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]motilin from human MOTR |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199368
((9R,12R,15S)-12-isopropyl-9-(4-methoxy-benzyl)-15-...)Show SMILES CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](Cc2ccc(OC)cc2)NCCOc2ccccc2CCCNC1=O)C(C)C Show InChI InChI=1S/C31H44N4O5/c1-5-9-25-29(36)33-17-8-11-23-10-6-7-12-27(23)40-19-18-32-26(20-22-13-15-24(39-4)16-14-22)30(37)35-28(21(2)3)31(38)34-25/h6-7,10,12-16,21,25-26,28,32H,5,8-9,11,17-20H2,1-4H3,(H,33,36)(H,34,38)(H,35,37)/t25-,26+,28+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Activity at human MOTR expressed in CHO cells assessed as inhibition of motilin-induced calcium release |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50199365
((E)-(9R,12R,15S)-9-(4-hydroxy-benzyl)-12-isopropyl...)Show SMILES CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](Cc2ccc(O)cc2)NCCOc2ccccc2\C=C\CNC1=O)C(C)C |t:32| Show InChI InChI=1S/C30H40N4O5/c1-4-8-24-28(36)32-16-7-10-22-9-5-6-11-26(22)39-18-17-31-25(19-21-12-14-23(35)15-13-21)29(37)34-27(20(2)3)30(38)33-24/h5-7,9-15,20,24-25,27,31,35H,4,8,16-19H2,1-3H3,(H,32,36)(H,33,38)(H,34,37)/b10-7+/t24-,25+,27+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 74 | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc.
Curated by ChEMBL
| Assay Description
Activity at human MOTR expressed in CHO cells assessed as inhibition of motilin-induced calcium release |
J Med Chem 49: 7190-7 (2006)
Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH |
More data for this
Ligand-Target Pair | |
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