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PubMed code 17127067

Compile data set for download or QSAR
Found 21 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Matrix metalloproteinase-9


(Homo sapiens (Human))		BDBM8465
PNG
((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO |r|
Show InChI InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1
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n/an/a 5n/an/an/an/an/an/a



Instituto Superior T£cnico

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MMP9

Bioorg Med Chem 15: 1266-74 (2007)


Article DOI: 10.1016/j.bmc.2006.11.017
BindingDB Entry DOI: 10.7270/Q2P26ZZX
More data for this
Ligand-Target Pair
Dihydrofolate reductase


(Homo sapiens (Human))		BDBM18050
PNG
(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Show SMILES CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(cc1)C(=O)N[C@@H](CCC(O)=O)C(O)=O |r|
Show InChI InChI=1S/C20H22N8O5/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30)(H,32,33)(H4,21,22,23,26,27)/t13-/m0/s1
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n/an/a 9n/an/an/an/an/an/a



Instituto Superior T£cnico

Curated by ChEMBL


Assay Description
Inhibition of DHFR using dihydrofolic acid substrate

Bioorg Med Chem 15: 1266-74 (2007)


Article DOI: 10.1016/j.bmc.2006.11.017
BindingDB Entry DOI: 10.7270/Q2P26ZZX
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Matrix metalloproteinase-14


(Homo sapiens (Human))		BDBM8465
PNG
((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO |r|
Show InChI InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1
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n/an/a 23n/an/an/an/an/an/a



Instituto Superior T£cnico

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MMP14

Bioorg Med Chem 15: 1266-74 (2007)


Article DOI: 10.1016/j.bmc.2006.11.017
BindingDB Entry DOI: 10.7270/Q2P26ZZX
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))		BDBM8465
PNG
((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO |r|
Show InChI InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1
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n/an/a 24n/an/an/an/an/an/a



Instituto Superior T£cnico

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MMP2

Bioorg Med Chem 15: 1266-74 (2007)


Article DOI: 10.1016/j.bmc.2006.11.017
BindingDB Entry DOI: 10.7270/Q2P26ZZX
More data for this
Ligand-Target Pair
Dihydrofolate reductase


(Homo sapiens (Human))		BDBM18050
PNG
(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Show SMILES CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(cc1)C(=O)N[C@@H](CCC(O)=O)C(O)=O |r|
Show InChI InChI=1S/C20H22N8O5/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30)(H,32,33)(H4,21,22,23,26,27)/t13-/m0/s1
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n/an/a 35n/an/an/an/an/an/a



Instituto Superior T£cnico

Curated by ChEMBL


Assay Description
Inhibition of DHFR using folic acid substrate

Bioorg Med Chem 15: 1266-74 (2007)


Article DOI: 10.1016/j.bmc.2006.11.017
BindingDB Entry DOI: 10.7270/Q2P26ZZX
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Dihydrofolate reductase


(Homo sapiens (Human))		BDBM50199731
PNG
(CHEMBL244883 | methotrexate gamma-hydroxamic acid)
Show SMILES CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(cc1)C(=O)N[C@@H](CCC(=O)NO)C(O)=O
Show InChI InChI=1S/C20H23N9O5/c1-29(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(30)28-34/h2-5,8,13,34H,6-7,9H2,1H3,(H,25,31)(H,28,30)(H,32,33)(H4,21,22,23,26,27)/t13-/m0/s1
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n/an/a 70n/an/an/an/an/an/a



Instituto Superior T£cnico

Curated by ChEMBL


Assay Description
Inhibition of DHFR using dihydrofolic acid substrate

Bioorg Med Chem 15: 1266-74 (2007)


Article DOI: 10.1016/j.bmc.2006.11.017
BindingDB Entry DOI: 10.7270/Q2P26ZZX
More data for this
Ligand-Target Pair
Matrilysin


(Homo sapiens (Human))		BDBM8465
PNG
((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO |r|
Show InChI InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1
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n/an/a 100n/an/an/an/an/an/a



Instituto Superior T£cnico

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MMP7

Bioorg Med Chem 15: 1266-74 (2007)


Article DOI: 10.1016/j.bmc.2006.11.017
BindingDB Entry DOI: 10.7270/Q2P26ZZX
More data for this
Ligand-Target Pair
Dihydrofolate reductase


(Homo sapiens (Human))		BDBM50199735
PNG
(CHEMBL388879 | methotrexate gamma-L-proline-hydrox...)
Show SMILES CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(cc1)C(=O)N[C@@H](CCC(=O)N1CCC[C@H]1C(=O)NO)C(O)=O
Show InChI InChI=1S/C25H30N10O6/c1-34(12-14-11-28-21-19(29-14)20(26)31-25(27)32-21)15-6-4-13(5-7-15)22(37)30-16(24(39)40)8-9-18(36)35-10-2-3-17(35)23(38)33-41/h4-7,11,16-17,41H,2-3,8-10,12H2,1H3,(H,30,37)(H,33,38)(H,39,40)(H4,26,27,28,31,32)/t16-,17-/m0/s1
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n/an/a 120n/an/an/an/an/an/a



Instituto Superior T£cnico

Curated by ChEMBL


Assay Description
Inhibition of DHFR using dihydrofolic acid substrate

Bioorg Med Chem 15: 1266-74 (2007)


Article DOI: 10.1016/j.bmc.2006.11.017
BindingDB Entry DOI: 10.7270/Q2P26ZZX
More data for this
Ligand-Target Pair
Dihydrofolate reductase


(Homo sapiens (Human))		BDBM50199735
PNG
(CHEMBL388879 | methotrexate gamma-L-proline-hydrox...)
Show SMILES CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(cc1)C(=O)N[C@@H](CCC(=O)N1CCC[C@H]1C(=O)NO)C(O)=O
Show InChI InChI=1S/C25H30N10O6/c1-34(12-14-11-28-21-19(29-14)20(26)31-25(27)32-21)15-6-4-13(5-7-15)22(37)30-16(24(39)40)8-9-18(36)35-10-2-3-17(35)23(38)33-41/h4-7,11,16-17,41H,2-3,8-10,12H2,1H3,(H,30,37)(H,33,38)(H,39,40)(H4,26,27,28,31,32)/t16-,17-/m0/s1
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n/an/a 130n/an/an/an/an/an/a



Instituto Superior T£cnico

Curated by ChEMBL


Assay Description
Inhibition of DHFR using folic acid substrate

Bioorg Med Chem 15: 1266-74 (2007)


Article DOI: 10.1016/j.bmc.2006.11.017
BindingDB Entry DOI: 10.7270/Q2P26ZZX
More data for this
Ligand-Target Pair
Dihydrofolate reductase


(Homo sapiens (Human))		BDBM50199733
PNG
(CHEMBL396296 | methotrexate gamma-L-phenylalanineh...)
Show SMILES CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(cc1)C(=O)N[C@@H](CCC(=O)N[C@@H](Cc1ccccc1)C(=O)NO)C(O)=O
Show InChI InChI=1S/C29H32N10O6/c1-39(15-18-14-32-25-23(33-18)24(30)36-29(31)37-25)19-9-7-17(8-10-19)26(41)35-20(28(43)44)11-12-22(40)34-21(27(42)38-45)13-16-5-3-2-4-6-16/h2-10,14,20-21,45H,11-13,15H2,1H3,(H,34,40)(H,35,41)(H,38,42)(H,43,44)(H4,30,31,32,36,37)/t20-,21-/m0/s1
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n/an/a 170n/an/an/an/an/an/a



Instituto Superior T£cnico

Curated by ChEMBL


Assay Description
Inhibition of DHFR using dihydrofolic acid substrate

Bioorg Med Chem 15: 1266-74 (2007)


Article DOI: 10.1016/j.bmc.2006.11.017
BindingDB Entry DOI: 10.7270/Q2P26ZZX
More data for this
Ligand-Target Pair
Dihydrofolate reductase


(Homo sapiens (Human))		BDBM50199731
PNG
(CHEMBL244883 | methotrexate gamma-hydroxamic acid)
Show SMILES CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(cc1)C(=O)N[C@@H](CCC(=O)NO)C(O)=O
Show InChI InChI=1S/C20H23N9O5/c1-29(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(30)28-34/h2-5,8,13,34H,6-7,9H2,1H3,(H,25,31)(H,28,30)(H,32,33)(H4,21,22,23,26,27)/t13-/m0/s1
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n/an/a 170n/an/an/an/an/an/a



Instituto Superior T£cnico

Curated by ChEMBL


Assay Description
Inhibition of DHFR using folic acid substrate

Bioorg Med Chem 15: 1266-74 (2007)


Article DOI: 10.1016/j.bmc.2006.11.017
BindingDB Entry DOI: 10.7270/Q2P26ZZX
More data for this
Ligand-Target Pair
Dihydrofolate reductase


(Homo sapiens (Human))		BDBM50199733
PNG
(CHEMBL396296 | methotrexate gamma-L-phenylalanineh...)
Show SMILES CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(cc1)C(=O)N[C@@H](CCC(=O)N[C@@H](Cc1ccccc1)C(=O)NO)C(O)=O
Show InChI InChI=1S/C29H32N10O6/c1-39(15-18-14-32-25-23(33-18)24(30)36-29(31)37-25)19-9-7-17(8-10-19)26(41)35-20(28(43)44)11-12-22(40)34-21(27(42)38-45)13-16-5-3-2-4-6-16/h2-10,14,20-21,45H,11-13,15H2,1H3,(H,34,40)(H,35,41)(H,38,42)(H,43,44)(H4,30,31,32,36,37)/t20-,21-/m0/s1
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n/an/a 250n/an/an/an/an/an/a



Instituto Superior T£cnico

Curated by ChEMBL


Assay Description
Inhibition of DHFR using folic acid substrate

Bioorg Med Chem 15: 1266-74 (2007)


Article DOI: 10.1016/j.bmc.2006.11.017
BindingDB Entry DOI: 10.7270/Q2P26ZZX
More data for this
Ligand-Target Pair
Matrilysin


(Homo sapiens (Human))		BDBM50199734
PNG
(CHEMBL267603 | folate gamma-L-phenylalaninehydroxa...)
Show SMILES Nc1nc2ncc(CNc3ccc(cc3)C(=O)N[C@@H](CCC(=O)N[C@@H](Cc3ccccc3)C(=O)NO)C(O)=O)nc2c(=O)[nH]1
Show InChI InChI=1S/C28H29N9O7/c29-28-35-23-22(26(41)36-28)32-18(14-31-23)13-30-17-8-6-16(7-9-17)24(39)34-19(27(42)43)10-11-21(38)33-20(25(40)37-44)12-15-4-2-1-3-5-15/h1-9,14,19-20,30,44H,10-13H2,(H,33,38)(H,34,39)(H,37,40)(H,42,43)(H3,29,31,35,36,41)/t19-,20-/m0/s1
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n/an/a 1.50E+4n/an/an/an/an/an/a



Instituto Superior T£cnico

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MMP7

Bioorg Med Chem 15: 1266-74 (2007)


Article DOI: 10.1016/j.bmc.2006.11.017
BindingDB Entry DOI: 10.7270/Q2P26ZZX
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9


(Homo sapiens (Human))		BDBM50199733
PNG
(CHEMBL396296 | methotrexate gamma-L-phenylalanineh...)
Show SMILES CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(cc1)C(=O)N[C@@H](CCC(=O)N[C@@H](Cc1ccccc1)C(=O)NO)C(O)=O
Show InChI InChI=1S/C29H32N10O6/c1-39(15-18-14-32-25-23(33-18)24(30)36-29(31)37-25)19-9-7-17(8-10-19)26(41)35-20(28(43)44)11-12-22(40)34-21(27(42)38-45)13-16-5-3-2-4-6-16/h2-10,14,20-21,45H,11-13,15H2,1H3,(H,34,40)(H,35,41)(H,38,42)(H,43,44)(H4,30,31,32,36,37)/t20-,21-/m0/s1
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n/an/a 1.50E+4n/an/an/an/an/an/a



Instituto Superior T£cnico

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MMP9

Bioorg Med Chem 15: 1266-74 (2007)


Article DOI: 10.1016/j.bmc.2006.11.017
BindingDB Entry DOI: 10.7270/Q2P26ZZX
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9


(Homo sapiens (Human))		BDBM50199734
PNG
(CHEMBL267603 | folate gamma-L-phenylalaninehydroxa...)
Show SMILES Nc1nc2ncc(CNc3ccc(cc3)C(=O)N[C@@H](CCC(=O)N[C@@H](Cc3ccccc3)C(=O)NO)C(O)=O)nc2c(=O)[nH]1
Show InChI InChI=1S/C28H29N9O7/c29-28-35-23-22(26(41)36-28)32-18(14-31-23)13-30-17-8-6-16(7-9-17)24(39)34-19(27(42)43)10-11-21(38)33-20(25(40)37-44)12-15-4-2-1-3-5-15/h1-9,14,19-20,30,44H,10-13H2,(H,33,38)(H,34,39)(H,37,40)(H,42,43)(H3,29,31,35,36,41)/t19-,20-/m0/s1
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n/an/a 2.20E+4n/an/an/an/an/an/a



Instituto Superior T£cnico

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MMP9

Bioorg Med Chem 15: 1266-74 (2007)


Article DOI: 10.1016/j.bmc.2006.11.017
BindingDB Entry DOI: 10.7270/Q2P26ZZX
More data for this
Ligand-Target Pair
Matrilysin


(Homo sapiens (Human))		BDBM50199733
PNG
(CHEMBL396296 | methotrexate gamma-L-phenylalanineh...)
Show SMILES CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(cc1)C(=O)N[C@@H](CCC(=O)N[C@@H](Cc1ccccc1)C(=O)NO)C(O)=O
Show InChI InChI=1S/C29H32N10O6/c1-39(15-18-14-32-25-23(33-18)24(30)36-29(31)37-25)19-9-7-17(8-10-19)26(41)35-20(28(43)44)11-12-22(40)34-21(27(42)38-45)13-16-5-3-2-4-6-16/h2-10,14,20-21,45H,11-13,15H2,1H3,(H,34,40)(H,35,41)(H,38,42)(H,43,44)(H4,30,31,32,36,37)/t20-,21-/m0/s1
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n/an/a 4.40E+4n/an/an/an/an/an/a



Instituto Superior T£cnico

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MMP7

Bioorg Med Chem 15: 1266-74 (2007)


Article DOI: 10.1016/j.bmc.2006.11.017
BindingDB Entry DOI: 10.7270/Q2P26ZZX
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))		BDBM50199733
PNG
(CHEMBL396296 | methotrexate gamma-L-phenylalanineh...)
Show SMILES CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(cc1)C(=O)N[C@@H](CCC(=O)N[C@@H](Cc1ccccc1)C(=O)NO)C(O)=O
Show InChI InChI=1S/C29H32N10O6/c1-39(15-18-14-32-25-23(33-18)24(30)36-29(31)37-25)19-9-7-17(8-10-19)26(41)35-20(28(43)44)11-12-22(40)34-21(27(42)38-45)13-16-5-3-2-4-6-16/h2-10,14,20-21,45H,11-13,15H2,1H3,(H,34,40)(H,35,41)(H,38,42)(H,43,44)(H4,30,31,32,36,37)/t20-,21-/m0/s1
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n/an/a 6.00E+4n/an/an/an/an/an/a



Instituto Superior T£cnico

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MMP2

Bioorg Med Chem 15: 1266-74 (2007)


Article DOI: 10.1016/j.bmc.2006.11.017
BindingDB Entry DOI: 10.7270/Q2P26ZZX
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))		BDBM50199734
PNG
(CHEMBL267603 | folate gamma-L-phenylalaninehydroxa...)
Show SMILES Nc1nc2ncc(CNc3ccc(cc3)C(=O)N[C@@H](CCC(=O)N[C@@H](Cc3ccccc3)C(=O)NO)C(O)=O)nc2c(=O)[nH]1
Show InChI InChI=1S/C28H29N9O7/c29-28-35-23-22(26(41)36-28)32-18(14-31-23)13-30-17-8-6-16(7-9-17)24(39)34-19(27(42)43)10-11-21(38)33-20(25(40)37-44)12-15-4-2-1-3-5-15/h1-9,14,19-20,30,44H,10-13H2,(H,33,38)(H,34,39)(H,37,40)(H,42,43)(H3,29,31,35,36,41)/t19-,20-/m0/s1
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n/an/a 6.50E+4n/an/an/an/an/an/a



Instituto Superior T£cnico

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MMP2

Bioorg Med Chem 15: 1266-74 (2007)


Article DOI: 10.1016/j.bmc.2006.11.017
BindingDB Entry DOI: 10.7270/Q2P26ZZX
More data for this
Ligand-Target Pair
Matrix metalloproteinase-14


(Homo sapiens (Human))		BDBM50199733
PNG
(CHEMBL396296 | methotrexate gamma-L-phenylalanineh...)
Show SMILES CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(cc1)C(=O)N[C@@H](CCC(=O)N[C@@H](Cc1ccccc1)C(=O)NO)C(O)=O
Show InChI InChI=1S/C29H32N10O6/c1-39(15-18-14-32-25-23(33-18)24(30)36-29(31)37-25)19-9-7-17(8-10-19)26(41)35-20(28(43)44)11-12-22(40)34-21(27(42)38-45)13-16-5-3-2-4-6-16/h2-10,14,20-21,45H,11-13,15H2,1H3,(H,34,40)(H,35,41)(H,38,42)(H,43,44)(H4,30,31,32,36,37)/t20-,21-/m0/s1
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n/an/a 7.00E+4n/an/an/an/an/an/a



Instituto Superior T£cnico

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MMP14

Bioorg Med Chem 15: 1266-74 (2007)


Article DOI: 10.1016/j.bmc.2006.11.017
BindingDB Entry DOI: 10.7270/Q2P26ZZX
More data for this
Ligand-Target Pair
Matrix metalloproteinase-14


(Homo sapiens (Human))		BDBM50199734
PNG
(CHEMBL267603 | folate gamma-L-phenylalaninehydroxa...)
Show SMILES Nc1nc2ncc(CNc3ccc(cc3)C(=O)N[C@@H](CCC(=O)N[C@@H](Cc3ccccc3)C(=O)NO)C(O)=O)nc2c(=O)[nH]1
Show InChI InChI=1S/C28H29N9O7/c29-28-35-23-22(26(41)36-28)32-18(14-31-23)13-30-17-8-6-16(7-9-17)24(39)34-19(27(42)43)10-11-21(38)33-20(25(40)37-44)12-15-4-2-1-3-5-15/h1-9,14,19-20,30,44H,10-13H2,(H,33,38)(H,34,39)(H,37,40)(H,42,43)(H3,29,31,35,36,41)/t19-,20-/m0/s1
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n/an/a 8.00E+4n/an/an/an/an/an/a



Instituto Superior T£cnico

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MMP14

Bioorg Med Chem 15: 1266-74 (2007)


Article DOI: 10.1016/j.bmc.2006.11.017
BindingDB Entry DOI: 10.7270/Q2P26ZZX
More data for this
Ligand-Target Pair
Matrilysin


(Homo sapiens (Human))		BDBM50199731
PNG
(CHEMBL244883 | methotrexate gamma-hydroxamic acid)
Show SMILES CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(cc1)C(=O)N[C@@H](CCC(=O)NO)C(O)=O
Show InChI InChI=1S/C20H23N9O5/c1-29(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(30)28-34/h2-5,8,13,34H,6-7,9H2,1H3,(H,25,31)(H,28,30)(H,32,33)(H4,21,22,23,26,27)/t13-/m0/s1
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n/an/a 1.00E+5n/an/an/an/an/an/a



Instituto Superior T£cnico

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MMP7

Bioorg Med Chem 15: 1266-74 (2007)


Article DOI: 10.1016/j.bmc.2006.11.017
BindingDB Entry DOI: 10.7270/Q2P26ZZX
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%